Cited by 8Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration MechanismsDementia and Cognitive Impairment Research

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Special issue on neurodegenerative diseases and their therapeutic approaches

Open access
Kim, Jungsu, Mook-Jung, Inhee·2015·Experimental & Molecular Medicine

Abstract

Aging is the strongest risk factor for most neurodegenerative disorders, such as Alzheimer’s disease (AD), Parkinson’s disease, Huntington’s disease and amyotrophic lateral sclerosis. As the aging population is increasing, these neurodegenerative disorders are becoming major social issues in many countries. Interestingly, these diseases share a common pathological phenotype; the accumulation of misfolded and aggregated proteins in the brain. Mounting evidence suggests that there are mechanistic links between toxic protein aggregation and neurodegenerative diseases. With a better understanding of the pathogenesis of these disorders, discovery efforts for disease-modifying therapeutics have markedly increased in recent years. This special issue, titled ‘Neurodegenerative diseases and their therapeutic approaches’, discusses the underlying pathogenic mechanisms and therapeutic implications for AD and other age-associated neurodegenerative disorders.

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Crossref · 10.1038/emm.2015.13

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Metadata

Authors
Kim, J., & Mook-Jung, I.
Affiliations
Mayo Clinic (US)
Venue
Experimental & Molecular Medicine
Published
2015-03-13
Volume
47
Issue
3
Pages
e146-e146
ISSN
  • 1226-3613 (ISSN-L)
  • 2092-6413
OpenAlex
W2021281334
Cited by
8
References
1
Citations by year
2026: 2 · 2024: 1 · 2023: 2 · 2022: 1 · 2020: 1 · 2015: 1
Type
journal article
Language
en
Open access
Locations
  • Experimental & Molecular Medicine (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (submittedVersion, cc-by-nc-nd)
  • PubMed Central (submittedVersion, cc-by-nc-nd)
Funders
  • Seoul National University
  • College of Medicine, Seoul National University
Topics
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
  • Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Keywords
neurodegenerative diseases, Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, aging, protein aggregation, protein misfolding, disease-modifying therapy, pathogenesis
MeSH terms
Humans, Neurodegenerative Diseases

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