Affibody molecules as engineered protein drugs

Frejd, Fredrik Y, Kim, Kyu-Tae·2017·Experimental & Molecular Medicine

DOI 10.1038/emm.2017.35

Cited by (226)

Items 201–226 of 226

N-terminal cysteine as minimalistic handle for dual, site-selective bioconjugation: application to an anti-HER2 affibody reveals synergy of two conjugated drugs
Ana Novak, Florian Kersaudy, Sylvie Berger, Séverine Morisset‐Lopez, François Lefoulon, Carlo Pifferi, Vincent Aucagne · 2023 · ChemRxiv
Physicochemical Stimulus-Responsive Systems Targeted with Antibody Derivatives
Rezvan Mohammadi, Sepideh Ghani, Roghaye Arezumand, Shohreh Farhadi, Yalda Khazaei‐Poul, Bahram Kazemi, Fatemeh Yarian, Somaye Noruzi, Abbas Alibakhshi, Mahsa Jalili et al. · 2023 · Current Molecular Medicine
Bioinspired, Biomimetic Nanomedicines
Şenay Hamarat Şanlıer, Ayça Erek, Habibe Yılmaz · 2023 · Recent advances in biotechnology
Non-invasive HER2 detection in ovarian and breast cancer xenografts with 99m Tc-(HE) 3 Z HER2:V2
Xianwen Hu, Hongyu Hu, Dandan Li, Pan Wang, Jiong Cai · 2024 · Research Square
Engineering the Mechanical Stability of a Therapeutic Affibody/PD-L1 Complex by Anchor Point Selection
Byeongseon Yang, Diego E. B. Gomes, Zhaowei Liu, Mariana Sá Santos, Jiajun Li, Rafael C. Bernardi, Michael A. Nash · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
Mn(II)-alapú diagnosztikai szerek: az alapkutatástól a célzott diagnosztikai eljárásokig
Balázs Váradi, Gergő Zoltán Sajtos, Károly Brezovcsik, Zoltán Szűcs, Stefan Eugen Szedlacsek, Gábor Nagy, Gyula Tircsó · 2024 · Scientia et Securitas
High-binding affinity nanobody against SARS-CoV-2 XBB.1.5: Computational-based protein engineering
Phoomintara Longsompurana, Napat Kongtaworn, Rungtiva P. Poo-arporn, Thanyada Rungrotmongkol · 2025 · Journal of Metals Materials and Minerals
Functional Assays for Screening Protein Biotherapeutics
Maureen H. Beresini, Kelly M. Loyet · 2025
Pharmacophore-driven antibody discovery on the yeast surface
Manjie Huang, Sean J. Williams, Vikas D. Trivedi, Nikhil U. Nair, James A. Van Deventer · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
Versatile fluorescent homobifunctional crosslinkers: expedient synthesis and application to di-affibody constructs for specific HER2+ cancer cell recognition
Eric Kaya, Fabienne Fasani, Carlo Pifferi, Catherine Grillon, Vincent Aucagne, Josef Hamáček · 2025 · Bioorganic & Medicinal Chemistry
Diffusion of Affibody molecules in extracellular matrix mimetic hydrogels and the effect of albumin binding
Julia Parlow, Anna Sandegren, Rezan Güler, Ida Karlberg, Fredrik Y. Frejd, Helen Sjögren, Per Hansson · 2025 · International Journal of Biological Macromolecules
Investigating probe-receptor interactions and enhancing fluorescence guided surgery with fluorescence lifetime imaging and NF-800 in HER-2 positive esophageal adenocarcinoma
Francesca La Cava, Francesca Arena, Daniele Faletto, Margherita Iaboni, Federico Crivellin, Alessia Cordaro, Miriam Roberto, Federica Pozzi, Francesco Fersini, Giovanni Valbusa et al. · 2025 · Scientific Reports
Additional file 1 of Engineering PD-1-targeted small protein variants for in vitro diagnostics and in vivo PET imaging
Joanna Maria Mierzwicka, Hana Petroková, Leona Raskova Kafkova, Petr Kosztyu, Jiří Černý, Milan Kuchař, Petřík, Miloš, Kateřina Dvořáková Bendová, Kristýna Krasulová, Yaroslava Groza et al. · 2024 · Figshare
Libraries of dynamic peptides based on reversible native chemical ligation
Cristian-Victor Reţe · 2018 · theses.fr (ABES)
New Generations of Antibodies and Scaffold Proteins as a Way to Create Highly Selective Conjugates for Oncology
I.V. Shulcheva, A. B. Ulitin · 2026 · Biomedical Chemistry Research and Methods
Developing treatment strategies to optimize outcomes in patients with psoriatic arthritis
Fadi Kharouf, Aiman Arraf, Vinod Chandran · 2026 · Expert Review of Clinical Pharmacology
One-Pot Orthogonal Dual Functionalization of mi3 Self-Assembling Protein Nanoparticles via Sortase A and SpyCatcher/SpyTag Ligation
Liqiang Wei, Hongfei Wang, Chunyue Du, Antony Kam, Shining Loo · 2026 · Bioconjugate Chemistry
Bis‐ S ‐Glycosylation of Disulfides
Shiyang Xu, Fei Hu, Shuoyingjie Wang, W H Wang, Y Li, Zhiyao He, Rong Tian, Xia Zhang, Yingwei Wang, Dawen Niu · 2026 · Angewandte Chemie
Integrating Tumor Targeting and Half-Life Extension into a Dual-Surfaced Single-Domain ADAPT Protein
Emma Larsson, Moeen Ud‐din, Athanasios Bitzios, Enrique Recasens Pérez-Vera, Hanna Tegel, Anna Orlova, Толмачев Владимир Максимилианович, Anzhelika Vorobyeva, Sophia Hober · 2026 · Molecular Pharmaceutics
Optimization of Affibody Affinity to Improve Distribution in Tumor Models
Bryce M. Bower, Gabrielle M. Ho, Sven A. Saemundsson, Andrew P. Goodwin, Jennifer N. Cha · 2026 · Biomacromolecules
Theranostics: integrating diagnostics and therapy for precision medicine and personalized healthcare
Kushagra Khanna, Pankaj Kumar, Mogana Sundari Rajagopal, Marwan Abdelmahmoud Abdelkarim Maki, Najwan Khaleel Jubair, Wan Hamirul Bahrin Wan Kamal, Siti Mohd Janib · 2026 · Health and Technology
EGFR Specific Affibody for Diagnostic Detection and Therapeutic Targeting of Thyroid Cancer Cells
Nastaran Masoudi-Khoram, Mahboobeh Nazari, Mohammad E. Khamseh, Sara Cheraghi · 2026 · Research Square
Antibody Discovery and Therapeutics in Spondyloarthritis: Recent Advances and Future Directions
Kwai Wei Chan, Ghee Chong Koo, Che Kang Lim · 2026 · Antibodies
Affibody-based approaches as potential therapeutics for breast cancer: mechanisms, applications, and future perspectives
Yao Ru, Keghon Kasparian, Yidong Zhou, Qiang Sun, Armando E. Giuliano, Bo Pan, Shengxi Chen, Xiaojiang Cui · 2026 · Cell investigation.
Computational design and translational development of TCR-mimic scFv antibodies for peptide-HLA neoantigen targeting
Sarfaraz K. Niazi, Matthias Magoola, Zamara Mariam · 2026 · npj Drug Discovery.
BindingDB Entry 50018699: Non-covalent albumin-binding ligands for extending the circulating half-life of small biotherapeutics.
BindingDB · 2024 · UC San Diego