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Potential use of biomarkers in acute kidney injury: report and summary of recommendations from the 10th Acute Dialysis Quality Initiative consensus conference
Open accessAbstract
Over the last decade there has been considerable progress in the discovery and development of biomarkers of kidney disease, and several have now been evaluated in different clinical settings. While there is a growing literature on the performance of various biomarkers in clinical studies, there is limited information on how these biomarkers would be utilized by clinicians to manage patients with acute kidney injury (AKI). Recognizing this gap in knowledge, we convened the 10th Acute Dialysis Quality Initiative (ADQI) meeting to review the literature on biomarkers in AKI and their application in clinical practice. We asked an international group of experts to assess four broad areas for biomarker utilization for AKI: risk assessment, diagnosis and staging; differential diagnosis; prognosis and management and novel physiological techniques including imaging. This article provides a summary of the key findings and recommendations of the group, to equip clinicians to effectively use biomarkers in AKI.
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Cited by
The definition of acute kidney injury and its use in practice
Thomas, M. E., Blaine, C., Dawnay, A., Devonald, M. A. J., Ftouh, S., Laing, C., Latchem, S., Lewington, A., Milford, D. V., & Ostermann, M. (2015) · Kidney International · doi:10.1038/ki.2014.328 · Cited by 722
Ostermann, M., Zarbock, A., Goldstein, S., Kashani, K., Macedo, E., Murugan, R., Bell, M., Forni, L., Guzzi, L., Joannidis, M., et al. (2020) · JAMA Network Open · doi:10.1001/jamanetworkopen.2020.19209 · Cited by 677
Self-citationCalzavacca, P., Licari, E., & Bellomo, R. (2010) · Surgical Intensive Care Medicine · doi:10.1007/978-0-387-77893-8_38 · Cited by 533
Recovery after Acute Kidney Injury
Kellum, J. A., Sileanu, F. E., Bihorac, A., Hoste, E. A. J., & Chawla, L. S. (2017) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201604-0799oc · Cited by 520
Self-citationSepsis-Associated Acute Kidney Injury
Manrique-Caballero, C. L., Del Rio-Pertuz, G., & Gomez, H. (2021) · Critical Care Clinics · doi:10.1016/j.ccc.2020.11.010 · Cited by 312
Metadata
- Authors
- Murray, P. T., Mehta, R. L., Shaw, A., Ronco, C., Endre, Z., Kellum, J. A., Chawla, L. S., Cruz, D., Ince, C., & Okusa, M. D.
- Venue
- Kidney International
- Publisher
- Elsevier BV
- Published
- 2014-03
- Volume
- 85
- Issue
- 3
- Pages
- 513-521
- ISSN
- 0085-2538 (ISSN-L)
- OpenAlex
- W1970454678
- Cited by
- 420
- References
- 0
- FWCI
- 25.41
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Potential use of biomarkers in acute kidney injury: report and summary of recommendations from the 10th Acute Dialysis Quality Initiative consensus conference. https://app.cochat.ai/papers/10.1038/ki.2013.374
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- Murray, P. T., Mehta, R. L., Shaw, A., Ronco, C., Endre, Z., Kellum, J. A., Chawla, L. S., Cruz, D., Ince, C., & Okusa, M. D. (2014). Potential use of biomarkers in acute kidney injury: report and summary of recommendations from the 10th Acute Dialysis Quality Initiative consensus conference. Kidney International. https://doi.org/10.1038/ki.2013.374
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