Clonal diversity of recurrently mutated genes in myelodysplastic syndromes

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Items 101–200 of 284

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2. NPM1-Mutated Myeloid Neoplasms with <20% Blasts: A Really Distinct Clinico-Pathologic Entity?
   Fabio Forghieri, Vincenzo Nasillo, Ambra Paolini, Francesca Bettelli, Valeria Pioli, Davide Giusti, Andrea Gilioli, Corrado Colasante, Gloria Acquaviva, Giovanni Riva et al. · 2020 · International Journal of Molecular Sciences
3. High concordance of genomic and cytogenetic aberrations between peripheral blood and bone marrow in myelodysplastic syndrome (MDS)
   A M Mohamedali, Joop A. Gäken, Momin Ahmed, F MALIK, Alexander Smith, S Best, Syed A. Mian, Terry J. Gaymes, Robin M. Ireland, Austin Gladston Kulasekararaj et al. · 2015 · Leukemia
4. Lymphohematopoietic cancers induced by chemicals and other agents and their implications for risk evaluation: An overview
   David A. Eastmond, Nagalakshmi Keshava, Babasaheb R. Sonawane · 2014 · Mutation Research/Reviews in Mutation Research
5. ARID1A mutations and expression loss in non-small cell lung carcinomas: clinicopathologic and molecular analysis
   Yin Pun Hung, Amanda J. Redig, Jason L. Hornick, Lynette Marie Sholl · 2020 · Modern Pathology
6. Somatic mutations and epigenetic abnormalities in myelodysplastic syndromes
   Raphaël Itzykson, Olivier Kosmider, Pierre Fenaux · 2013 · Best Practice & Research Clinical Haematology
7. Asian Population Is More Prone to Develop High-Risk Myelodysplastic Syndrome, Concordantly with Their Propensity to Exhibit High-Risk Cytogenetic Aberrations
   Yan Jiang, Jean‐Richard Eveillard, Marie‐Anne Couturier, Benoît Soubise, Jian‐Min Chen, Sujun Gao, Audrey Basinko, Fréderic Morel, Nathalie Douet‐Guilbert, Marie‐Bérengère Troadec · 2021 · Cancers
8. Failure to Detect Mutations in U2AF1 due to Changes in the GRCh38 Reference Sequence
   Christopher A. Miller, Jason Walker, Travis Lee Jensen, William F. Hooper, Robert S. Fulton, Jeffrey S. Painter, Mikkael Aaron Sekeres, Timothy James Ley, David H. Spencer, Johannes B. Goll et al. · 2022 · Journal of Molecular Diagnostics
9. Prognostic models in myelodysplastic syndromes
   Rafael L. Bejar · 2013 · Hematology
10. Genetic Hierarchy of Acute Myeloid Leukemia: From Clonal Hematopoiesis to Molecular Residual Disease
    Jean‐Alain Martignoles, François Delhommeau, Pierre Hirsch · 2018 · International Journal of Molecular Sciences
11. Knockdown of HSPA9 induces TP53-dependent apoptosis in human hematopoietic progenitor cells
    Tuoen Liu, Kilannin Krysiak, Cara Lunn Shirai, Sanghyun Peter Kim, Jin Shao, Matthew Ndonwi, Matthew J. Walter · 2017 · PLoS ONE
12. Alterations of cohesin complex genes in acute myeloid leukemia: differential co-mutations, clinical presentation and impact on outcome
    Jan‐Niklas Eckardt, Sebastian Stasik, Christoph Röllig, Tim Sauer, Sebastian Scholl, Andreas Hochhaus, Martina Margrit Crysandt, Tim H. Brümmendorf, Ralph Naumann, Björn Steffen et al. · 2023 · Blood Cancer Journal
13. The prognostic significance of global aberrant alternative splicing in patients with myelodysplastic syndrome
    Yang, Yi-Tsung, Chiu, Yu-Chiao, Kao, Chein-Jun, Hou, Hsin-An, Lin, Chien-Chin, Tsai, Cheng-Hong, Tseng, Mei-Hsuan, Chou, Wen-Chien, Tien, Hwei-Fang · 2018 · Blood Cancer Journal
14. The Genetic Basis and Expanding Role of Molecular Analysis in the Diagnosis, Prognosis, and Therapeutic Design for Myelodysplastic Syndromes
    Grant E. Nybakken, Adam Bagg · 2014 · Journal of Molecular Diagnostics
15. Chromatin structure in cancer
    Meng Wang, Benjamin D. Sunkel, William C. Ray, Benjamin Z. Stanton · 2022 · BMC Molecular and Cell Biology
16. Recent advances in myelodysplastic syndromes: Molecular pathogenesis and its implications for targeted therapies
    Hironori Harada, Yuka Harada · 2015 · Cancer Science
17. Short telomere length and its correlation with gene mutations in myelodysplastic syndrome
    Sang Mee Hwang, Seon Young Kim, Jung Ah Kim, Hee-Sue Park, Si Nae Park, Kyongok Im, Kwantae Kim, Sung‐Min Kim, Dong Soon Lee · 2016 · Journal of Hematology & Oncology
18. Hallmarks of Splicing Defects in Cancer: Clinical Applications in the Era of Personalized Medicine
    Mohammad Alinoor Rahman, Farhana Nasrin, Sonali Bhattacharjee, Saikat Nandi · 2020 · Cancers
19. Therapy-Related Myeloid Neoplasms: Complex Interactions among Cytotoxic Therapies, Genetic Factors, and Aberrant Microenvironment
    Deepak Singhal, Monika Kutyna, Christopher Norman Hahn, Mithun Vinod Shah, Devendra Hiwase · 2024 · Blood Cancer Discovery
20. Splicing factor gene mutations in the myelodysplastic syndromes: impact on disease phenotype and therapeutic applications
    Andrea Pellagatti, Jacqueline Boultwood · 2016 · Advances in Biological Regulation
21. Molecular pathogenesis of disease progression in MLL-rearranged AML
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22. The Challenging World of Cytopenias: Distinguishing Myelodysplastic Syndromes From Other Disorders of Marrow Failure
    Amy Elizabeth Dezern, Mikkael Aaron Sekeres · 2014 · The Oncologist
23. Regulation and Dysregulation of Chromosome Structure in Cancer
    Denes Hnisz, Jurian Schuijers, Charles H. Li, Richard A. Young · 2017 · Annual Review of Cancer Biology
24. Implications of mutational spectrum in myelodysplastic syndromes based on targeted next-generation sequencing
    Yuanyuan Xu, Yan Li, Qingyu Xu, Yuelong Chen, Yu Jing, Yu Jing, Liping Dou, Jian Bo, Guangyuan Hou, Jing Guo et al. · 2017 · Oncotarget
25. Splicing factor mutant myelodysplastic syndromes: Recent advances
    Andrea Pellagatti, Jacqueline Boultwood · 2019 · Advances in Biological Regulation
26. The RNA binding protein FgRbp1 regulates specific pre-mRNA splicing via interacting with U2AF23 in Fusarium
    Minhui Wang, Tianling Ma, Haixia Wang, Jianzhao Liu, Yun Chen, Won‐Bo Shim, Zhonghua Ma · 2021 · Nature Communications
27. Comparison of myeloid blast counts and variant allele frequencies of gene mutations in myelodysplastic syndrome with excess blasts and secondary acute myeloid leukemia
    Xueyan Chen, Megan K. D. Othus, Brent Lee Wood, Roland B. Walter, Pamela Sue Becker, Mary‐Elizabeth M. Percival, Janis L. Abkowitz, Frederick R. Appelbaum, Elihu H. Estey · 2020 · Leukemia & lymphoma/Leukemia and lymphoma
28. Implications of Tumor Clonal Heterogeneity in the Era of Next-Generation Sequencing
    Meagan A. Jacoby, Eric James Duncavage, Matthew J. Walter · 2015 · Trends in cancer
29. Mutational profiling in patients with MDS: Ready for every-day use in the clinic?
    Ulrike Bacher, Alexander Kohlmann, Torsten Haferlach · 2014 · Best Practice & Research Clinical Haematology
30. Molecular mechanisms of the progression of myelodysplastic syndrome to secondary acute myeloid leukaemia and implication for therapy
    Chunli Dan, Jianxiang Chi, Li Wang · 2015 · Annals of Medicine
31. Prognostic value of SRSF2 mutations in patients with de novo myelodysplastic syndromes: A meta-analysis
    Xue Yan Zheng, Zhi Zhan, Duolan Naren, Jing Li, Tianyou Yan, Yuping Gong · 2017 · PLoS ONE
32. Impact of chromosome alterations, genetic mutations and clonal hematopoiesis of indeterminate potential (CHIP) on the classification and risk stratification of MDS
    Bani Bandana Ganguly, Debasis Banerjee, M B Agarwal · 2017 · Blood Cells Molecules and Diseases
33. Splicing factor mutations in the myelodysplastic syndromes: target genes and therapeutic approaches
    Richard Neil Armstrong, Violetta Steeples, Shalini Singh, Andrea Sanchi, Jacqueline Boultwood, Andrea Pellagatti · 2017 · Advances in Biological Regulation
34. Dynamics of Genome Alterations in Crohn's Disease–Associated Colorectal Carcinogenesis
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35. Myelodysplastic Syndrome-Associated SRSF2 Mutations Cause Splicing Changes by Altering Binding Motif Sequences
    So Masaki, Shun Ikeda, Asuka Hata, Yusuke Shiozawa, Ayana Kon, Seishi Ogawa, Kenji Suzuki, Fumihiko Hakuno, Shin‐Ichiro Takahashi, Naoyuki Kataoka · 2019 · Frontiers in Genetics
36. Genetic Predisposition to Myelodysplastic Syndrome in Clinical Practice
    Kristen E. Schratz, Amy Elizabeth Dezern · 2020 · Hematology/Oncology Clinics of North America
37. Sequential azacitidine plus lenalidomide in previously treated elderly patients with acute myeloid leukemia and higher risk myelodysplastic syndrome
    Rupa Narayan, Jacqueline Suen Garcia, Mary‐Elizabeth M. Percival, Caroline Berube, Steven E. Coutre, Jason R. Gotlib, Peter L. Greenberg, Michaela Liedtke, Rhonda Hewitt, Kathleen Regan et al. · 2015 · Leukemia & lymphoma/Leukemia and lymphoma
38. Genetics of Myelodysplastic Syndromes
    Caner Saygin, Lucy A. Godley · 2021 · Cancers
39. Genomic tools in acute myeloid leukemia: From the bench to the bedside
    Brian S. White, John F. DiPersio · 2014 · Cancer
40. TET2 expression level and 5-hydroxymethylcytosine are decreased in refractory cytopenia of childhood
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41. Prognostic value of U2AF1 mutant in patients with de novo myelodysplastic syndromes: a meta-analysis
    Hui‐Fang Wang, Nanchen Zhang, Xia Wu, Xue Yan Zheng, Yantao Ling, Yuping Gong · 2019 · Annals of Hematology
42. Myelodysplastic syndromes in the United States: an update for clinicians
    Jesse D. Troy, Ehab L. Atallah, Julia Turbiner Geyer, Wael Saber · 2014 · Annals of Medicine
43. Peripheral blood cell‐free DNA is an alternative tumor DNA source reflecting disease status in myelodysplastic syndromes
    Yasuhíro Suzuki, Akihiro Tomita, Fumika Nakamura, Chisako Iriyama, Mizuho Shirahata‐Adachi, Kazuyuki Shimada, Akimi Akashi, Yuichi Ishikawa, Norio Kaneda, Hitoshi Kiyoi · 2016 · Cancer Science
44. Myeloablative conditioning regimens with combined of haploidentical and cord blood transplantation for myelodysplastic syndrome patients
    Ke Peng, X-B Bao, X-H Hu, Jian Zhuang, X-J Wu, Yujuan Liu, X-F. He, Dapeng Wu, S-L Xue, Xiao Ma · 2017 · Bone Marrow Transplantation
45. Targeting TP53 Mutations in Myelodysplastic Syndromes
    Anthony Michael Hunter, David Andrew Sallman · 2019 · Hematology/Oncology Clinics of North America
46. Convergent Clonal Evolution of Signaling Gene Mutations Is a Hallmark of Myelodysplastic Syndrome Progression
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47. Discriminating myelodysplastic syndrome and other myeloid malignancies from non-clonal disorders by multiparametric analysis of automated cell data
    Seon Young Kim, Yumi Park, Hyunjin Kim, Jimyung Kim, Gye Cheol Kwon, Sun Hoe Koo · 2018 · Clinica Chimica Acta
48. Co-occurrence of cohesin complex and Ras signaling mutations during progression from myelodysplastic syndromes to secondary acute myeloid leukemia
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49. The genetics of myelodysplastic syndromes and the opportunities for tailored treatments
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50. The evolving role of next generation sequencing in myelodysplastic syndromes
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51. Retroviral insertional mutagenesis identifies the del(5q) genes, CXXC5, TIFAB and ETF1, as well as the Wnt pathway, as potential targets in del(5q) myeloid neoplasms
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52. SF3B1 mutant myelodysplastic syndrome: Recent advances
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53. Comprehensive analysis of genetic factors predicting overall survival in Myelodysplastic syndromes
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54. Causes of Clonal Hematopoiesis: a Review
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55. Perspective on how to approach molecular diagnostics in acute myeloid leukemia and myelodysplastic syndromes in the era of next-generation sequencing
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56. The clinical use of DNA methyltransferase inhibitors in myelodysplastic syndromes
    Abdallah Abou Zahr, Ehab Saad Aldin, Lisa Barbarotta, Nikolai Alexandrovich Podoltsev, Amer Methqal Zeidan · 2015 · Expert Review of Anticancer Therapy
57. Prognostic value and clinical feature of SF3B1 mutations in myelodysplastic syndromes: A meta-analysis
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58. Gene mutations and clonal architecture in myelodysplastic syndromes and changes upon progression to acute myeloid leukaemia and under treatment
    Juliane M. Stosch, Anezka Heumüller, Christoph Niemöller, Sabine Bleul, Maja Rothenberg‐Thurley, Julian Riba, Nathalie Renz, Katarzyna Szarc vel Szic, Dietmar Pfeifer, Marie Follo et al. · 2018 · British Journal of Haematology
59. Splicing factor mutations in the myelodysplastic syndromes: Role of key aberrantly spliced genes in disease pathophysiology and treatment
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60. Reduced levels of Hspa9 attenuate Stat5 activation in mouse B cells
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61. Cell Marker Accordion: interpretable single-cell and spatial omics annotation in health and disease
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62. Biomarkers in Acute Myeloid Leukemia: Leveraging Next Generation Sequencing Data for Optimal Therapeutic Strategies
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63. Genetic Testing in Acute Myeloid Leukemia and Myelodysplastic Syndromes
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64. The high frequency of the U2AF1 S34Y mutation and its association with isolated trisomy 8 in myelodysplastic syndrome in Asians, but not in Caucasians
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65. Impact of mutational studies on the diagnosis and the outcome of high-risk myelodysplastic syndromes and secondary acute myeloid leukemia patients treated with 5-azacytidine
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66. Allogeneic stem cell transplantation in myelodysplastic syndromes
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67. New Insights into the Pathogenesis of MDS and the rational therapeutic opportunities
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68. Acquired copy number alterations of miRNA genes in acute myeloid leukemia are uncommon
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69. Does a Diagnosis of Myelogenous Leukemia Require 20% Marrow Myeloblasts, and Does <5% Marrow Myeloblasts Represent a Remission? The History and Ambiguity of Arbitrary Diagnostic Boundaries in the Understanding of Myelodysplasia
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70. New Insight Into the Biology, Risk Stratification, and Targeted Treatment of Myelodysplastic Syndromes
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71. Mutational Spectrum of Fanconi Anemia Associated Myeloid Neoplasms
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72. Molecular Pathways in Clonal Hematopoiesis: From the Acquisition of Somatic Mutations to Transformation into Hematologic Neoplasm
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73. Whole-exome sequencing in del(5q) myelodysplastic syndromes in transformation to acute myeloid leukemia
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74. Clinical implications of somatic mutations in aplastic anemia and myelodysplastic syndrome in genomic age
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75. Targeted next‐generation sequencing using a multigene panel in myeloid neoplasms: Implementation in clinical diagnostics
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76. Navigating the contested borders between myelodysplastic syndrome and acute myeloid leukemia
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77. Treatment of Older Patients with High-Risk Myelodysplastic Syndromes (MDS): The Emerging Role of Allogeneic Hematopoietic Stem Cell Transplantation (Allo HSCT)
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79. Myelodysplastic syndromes: Biological and therapeutic consequences of the evolving molecular aberrations landscape
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80. A clinical, histopathological, and molecular study of two cases of VEXAS syndrome without a definitive myeloid neoplasm
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81. Molecular Genetic Biomarkers in Myeloid Malignancies
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82. The 5q deletion size in myeloid malignancies is correlated to additional chromosomal aberrations and to TP53 mutations
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85. The incidence, risk factors, and survival of acute myeloid leukemia secondary to myelodysplastic syndrome: A population‐based study
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92. The Prognostic Value of Early Detection of Minimal Residual Disease as Defined by Flow Cytometry and Gene Mutation Clearance for Myelodysplastic Syndrome Patients After Myeloablative Allogeneic Hematopoietic Stem-Cell Transplantation
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