Independence of familial transmission of mania and depression: results of the NIMH family study of affective spectrum disorders

Merikangas, K R; Cui, L; Heaton, L; Nakamura, E; Roca, C; Ding, J; Qin, H; Guo, W; Yao-Shugart, Y; Zarate, C; Angst, J

doi:10.1038/mp.2013.116

Independence of familial transmission of mania and depression: results of the NIMH family study of affective spectrum disorders

The goal of this study is to investigate the familial transmission of the spectrum of bipolar disorder in a nonclinical sample of probands with a broad range of manifestations of mood disorders. The sample included a total of 447 probands recruited from a clinically enriched community screening a…