Widespread splicing changes in human brain development and aging

Mazin, Pavel, Xiong, Jieyi, Liu, Xiling, Yan, Zheng, Zhang, Xiaoyu, Li, Mingshuang, He, Liu, Somel, Mehmet +11 more·2013·Molecular Systems Biology

Cited by (223)

Items 201–223 of 223

  1. The combination of differential expression and differential network connectivity analyses identifies RNA splicing and processing as common pathways altered with age across human tissues
    Caio M.P.F. Batalha, André Fujita, Nadja Cristhina de Souza-Pinto · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  2. Resolving chromatin interaction and transcriptional networks in mammalian nuclei
    Yajie Zhu · 2024
  3. Isoswitching in human brain development and aging
    Beril Erdogdu, Hyun Joo Ji, Zoe Rudnick, Mihaela Pertea, Steven L. Salzberg · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  4. Alternative splicing and the aging brain in AfrAbia: New frontiers in dementia research
    Suliyat Abiodun Aremu · 2025 · IBRO Neuroscience Reports
  5. QKI ensures splicing fidelity during cardiogenesis by engaging the U6 tri-snRNP to activate splicing at weak 5ʹ splice sites
    Maureen V. Akinyi, Wenjie Yao, Jakub Zeman, Clara Hipp, Deniz Bartsch, Laurence Heaven, Charlotte A. Le Roux, Anne C Starner, Fei Yuan, Mason D. Bartels et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  6. scBrainScope: cross-species multidimensional brain atlas
    Siying Qin, Yuexi Yang, Haoyu Wang, Mengrou Li, Yushan Deng, Yangfeng Chen, Changxiao Li, Lingmin Peng, Linlin Xu, Xiwen Qiu et al. · 2025 · Nucleic Acids Research
  7. Additional file 1 of Nuclear speckle specific hnRNP D-like prevents age- and AD-related cognitive decline by modulating RNA splicing
    Zhang, Qingyang, Zhang, Juan, Ye, Jin, Li, Xiaohui, Liu, Hongda, Ma, Xiaolin, Chao Wang, He, Keqiang, Zhang, Wei, Yuan, Ji et al. · 2021 · Figshare
  8. Additional file 3 of Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usage
    Emma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne · 2024 · Figshare
  9. Additional file 2 of Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usage
    Emma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne · 2024 · Figshare
  10. Additional file 6 of Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usage
    Emma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne · 2024 · Figshare
  11. Additional file 7 of Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usage
    Emma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne · 2024 · Figshare
  12. Additional file 1 of Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usage
    Emma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne · 2024 · Figshare
  13. Additional file 8 of Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usage
    Emma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne · 2024 · Figshare
  14. Additional file 4 of Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usage
    Emma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne · 2024 · Figshare
  15. Additional file 5 of Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usage
    Emma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne · 2024 · Figshare
  16. A combination of differential expression and network connectivity analyses identifies a common set of RNA splicing and processing genes altered with age across human tissues
    Caio M.P.F. Batalha, André Fujita, Nadja Cristhina de Souza-Pinto · 2025 · Aging
  17. Brain aging mediates region-specific transcriptomic alterations
    Adel B Alharbi · 2026 · Biosystems
  18. Locus-specific LINE-1 mRNA expression reflects cell-type- and stimulus-specific senescence states
    Minh N. Tran, Sihan Liu, Melody Baddoo, Emily C. Stow, Sudesh K Srivastav, Victoria P. Belancio · 2026 · Nucleic Acids Research
  19. Elevated intron retention implicates neuroinflammation in brains of individuals with alcohol use disorder
    Ru-Dong Li, Jill L. Reiter, Season K. Wyatt-Johnson, Chuan-Peng Dong, C. Smith, Nick Green, Hong-Yu Gao, S. R. Hauser, M. Kapoor, Julia Stevens et al. · 2026 · Brain Communications
  20. Alternative splicing dysregulation in CAG repeat expansion diseases
    Asmer Aliyeva, John D. Cleary, Hannah K. Shorrock, J. Andrew Berglund · 2026 · Trends in Neurosciences
  21. RNA dysregulation as a determinant of aging and neurodegenerative vulnerability
    Sawyer Randles, Gene Wei-Ming Yeo · 2026 · Trends in Cell Biology
  22. Caloric restriction drives age-dependent and integrated remodeling of RNA processing and lipid composition in mouse brain
    Spencer Tye, Josef P. Clark, Andrew Engeler, Anshit Singh, Rozalyn M. Anderson, Timothy W. Rhoads · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  23. IsoGraph resolves coordinated transcript choice and gene abundance in the aging human brain
    Alexis Bennett, Elisa Kain Johnson, Kynon JM Benjamin · 2026 · bioRxiv (Cold Spring Harbor Laboratory)