Widespread splicing changes in human brain development and aging
Mazin, Pavel, Xiong, Jieyi, Liu, Xiling, Yan, Zheng, Zhang, Xiaoyu, Li, Mingshuang, He, Liu, Somel, Mehmet +11 more·2013·Molecular Systems Biology
Cited by (223)
Items 201–223 of 223
- The combination of differential expression and differential network connectivity analyses identifies RNA splicing and processing as common pathways altered with age across human tissuesCaio M.P.F. Batalha, André Fujita, Nadja Cristhina de Souza-Pinto · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Resolving chromatin interaction and transcriptional networks in mammalian nucleiYajie Zhu · 2024
- Isoswitching in human brain development and agingBeril Erdogdu, Hyun Joo Ji, Zoe Rudnick, Mihaela Pertea, Steven L. Salzberg · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Alternative splicing and the aging brain in AfrAbia: New frontiers in dementia researchSuliyat Abiodun Aremu · 2025 · IBRO Neuroscience Reports
- QKI ensures splicing fidelity during cardiogenesis by engaging the U6 tri-snRNP to activate splicing at weak 5ʹ splice sitesMaureen V. Akinyi, Wenjie Yao, Jakub Zeman, Clara Hipp, Deniz Bartsch, Laurence Heaven, Charlotte A. Le Roux, Anne C Starner, Fei Yuan, Mason D. Bartels et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- scBrainScope: cross-species multidimensional brain atlasSiying Qin, Yuexi Yang, Haoyu Wang, Mengrou Li, Yushan Deng, Yangfeng Chen, Changxiao Li, Lingmin Peng, Linlin Xu, Xiwen Qiu et al. · 2025 · Nucleic Acids Research
- Additional file 1 of Nuclear speckle specific hnRNP D-like prevents age- and AD-related cognitive decline by modulating RNA splicingZhang, Qingyang, Zhang, Juan, Ye, Jin, Li, Xiaohui, Liu, Hongda, Ma, Xiaolin, Chao Wang, He, Keqiang, Zhang, Wei, Yuan, Ji et al. · 2021 · Figshare
- Additional file 3 of Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usageEmma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne · 2024 · Figshare
- Additional file 2 of Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usageEmma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne · 2024 · Figshare
- Additional file 6 of Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usageEmma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne · 2024 · Figshare
- Additional file 7 of Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usageEmma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne · 2024 · Figshare
- Additional file 1 of Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usageEmma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne · 2024 · Figshare
- Additional file 8 of Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usageEmma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne · 2024 · Figshare
- Additional file 4 of Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usageEmma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne · 2024 · Figshare
- Additional file 5 of Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usageEmma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne · 2024 · Figshare
- A combination of differential expression and network connectivity analyses identifies a common set of RNA splicing and processing genes altered with age across human tissuesCaio M.P.F. Batalha, André Fujita, Nadja Cristhina de Souza-Pinto · 2025 · Aging
- Brain aging mediates region-specific transcriptomic alterationsAdel B Alharbi · 2026 · Biosystems
- Locus-specific LINE-1 mRNA expression reflects cell-type- and stimulus-specific senescence statesMinh N. Tran, Sihan Liu, Melody Baddoo, Emily C. Stow, Sudesh K Srivastav, Victoria P. Belancio · 2026 · Nucleic Acids Research
- Elevated intron retention implicates neuroinflammation in brains of individuals with alcohol use disorderRu-Dong Li, Jill L. Reiter, Season K. Wyatt-Johnson, Chuan-Peng Dong, C. Smith, Nick Green, Hong-Yu Gao, S. R. Hauser, M. Kapoor, Julia Stevens et al. · 2026 · Brain Communications
- Alternative splicing dysregulation in CAG repeat expansion diseasesAsmer Aliyeva, John D. Cleary, Hannah K. Shorrock, J. Andrew Berglund · 2026 · Trends in Neurosciences
- RNA dysregulation as a determinant of aging and neurodegenerative vulnerabilitySawyer Randles, Gene Wei-Ming Yeo · 2026 · Trends in Cell Biology
- Caloric restriction drives age-dependent and integrated remodeling of RNA processing and lipid composition in mouse brainSpencer Tye, Josef P. Clark, Andrew Engeler, Anshit Singh, Rozalyn M. Anderson, Timothy W. Rhoads · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- IsoGraph resolves coordinated transcript choice and gene abundance in the aging human brainAlexis Bennett, Elisa Kain Johnson, Kynon JM Benjamin · 2026 · bioRxiv (Cold Spring Harbor Laboratory)