Engineering and Selection of Shuffled AAV Genomes: A New Strategy for Producing Targeted Biological Nanoparticles

Li, Wuping, Asokan, Aravind, Wu, Zhijian, Van Dyke, Terry, DiPrimio, Nina, Johnson, Jarrod S, Govindaswamy, Lakshmanan, Agbandje-McKenna, Mavis +6 more·2008·Molecular Therapy
DOI 10.1038/mt.2008.100

Cited by (261)

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  3. Gene Therapy Today and Tomorrow
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  22. Gene- and Cell-Based Therapy for Cardiovascular Disease
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  23. 4.33 Engineering Viruses For Gene Therapy
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  25. Engineered Bioactive Molecules
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    H. Miao, Carol · 2012 · Journal of Genetic Syndromes & Gene Therapy
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  28. The State of the Art and Future of Gene Medicines
    Frank Jacobs, Stephanie C. Gordts, Bart De Geest · 2013 · Wiley eBooks
  29. Strategies for improving adeno-associated viral infection of airway epithelial cells
    David D. Dickey · 2012
  30. Obstacles and Circumvention Strategies for Hematopoietic Stem Cell Transduction by Recombinant Adeno-associated Virus Vectors
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  31. Rapidly evolving adeno-associated virus vectors: increasing possibility of gene therapy with custom-made vectors
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  35. Genetic Modification of Adeno-Associated Virus Capsid for Enhanced Motor Neuron Delivery and Retrograde Transport
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  36. Engineering magnetic viral nanoheaters for targeted hyperthermia treatment of cancer
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  38. Canadian Journal of Cardiology Symposium Review Targeted Gene Therapy for the Treatment of Heart Failure
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  39. Modulation of adeno-associated virus transduction by the promyelocytic leukemia protein, arsenic trioxide, and proteasome inhibitors
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  40. The Role of Assembly-Activating Protein in the Capsid Assembly of Different Adeno-Associated Virus Serotypes
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  41. Chemical Modulation of AAV Trafficking
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  42. [Use of a new peroral anticoryza drug. Experience in the industrial medical practice].
    G Schäfer · 1971 · PubMed
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  44. RNA interference therapy for the Spinocerebellar ataxias
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  46. Understanding mechanisms of Adeno-associated virus vector transduction through pharmacological and biological approaches
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  47. AAV-Nrf2 Mediated Rescue of Oxidative Stress in Mouse Models
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  49. Advances in Overcoming Immune Responses following Hemophilia Gene
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  52. Faculty Opinions recommendation of A myocardium tropic adeno-associated virus (AAV) evolved by DNA shuffling and in vivo selection.
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  53. Cryo-EM reveals how adeno-associated virus engages its receptor AAVR and an investigation of the GPR108 ectodomain
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  54. Selection and characterization of targeted vector capsids from random adeno-associated virus type 2 (AAV-2) display peptide libraries
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  55. An Expanded Toolbox for Versatile Chemical Editing of Adeno‐Associated Virus
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  56. Adeno-associated virus (AAV) mediated advanced therapeutic interventions for inherited and non-inherited cardiac disorders
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  58. Développement d'un traitement de thérapie génique pour la glycogénose de type III
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  59. Distinct YY dinucleotide periodicity in adeno-associated virus DNA
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  60. Development of AAV vectors for the therapy of autoimmune and inflammatory diseases
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  61. TREATMENTS (NON-ANTIEPILEPTIC DRUGS) | Viral Vector Approaches for Antiepileptic Gene Therapy
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