Physiological Promoters Reduce the Genotoxic Risk of Integrating Gene Vectors

LMO2 -Associated Clonal T Cell Proliferation in Two Patients after Gene Therapy for SCID-X1

Hacein-Bey-Abina, S., Von Kalle, C., Schmidt, M., McCormack, M. P., Wulffraat, N., Leboulch, P., Lim, A., Osborne, C. S., Pawliuk, R., Morillon, E., et al. (2003) · Science · doi:10.1126/science.1088547 · Cited by 3,587

Plat-E: an efficient and stable system for transient packaging of retroviruses

MORITA, S., Kojima, T., & Kitamura, T. (2000) · Gene Therapy · doi:10.1038/sj.gt.3301206 · Cited by 1,660

Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1

Ott, M., Schmidt, M., Schwarzwaelder, K., Stein, S., Siler, U., Koehl, U., Glimm, H., Kühlcke, K., Schilz, A. J., Kunkel, H., et al. (2006) · Nature Medicine · doi:10.1038/nm1393 · Cited by 1,189

The protein CTCF is required for the enhancer blocking activity of vertebrate insulators

Bell, A. C., West, A. G., & Felsenfeld, G. (1999) · Cell · doi:10.1016/s0092-8674(00)81967-4 · Cited by 1,101

Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration

Montini, E., Cesana, D., Schmidt, M., Sanvito, F., Ponzoni, M., Bartholomae, C. C., Sergi, L. S., Benedicenti, F., Ambrosi, A., Serio, C. D., et al. (2006) · Nature Biotechnology · doi:10.1038/nbt1216 · Cited by 709

Murine Leukemia Induced by Retroviral Gene Marking

Li, Z., Düllmann, J., Schiedlmeier, B., Schmidt, M., Kalle, C. V., Meyer, J., Forster, M., Stocking, C., Wahlers, A., Frank, O., et al. (2002) · Science · doi:10.1126/science.1068893 · Cited by 653

The Basic Science of Oncology

Tannock, I. F., Hill, R. P., & Carey, R. W. (1989) · Plastic & Reconstructive Surgery · doi:10.1097/00006534-198905000-00037 · Cited by 473

Cell-culture assays reveal the importance of retroviral vector design for insertional genotoxicity

Modlich, U., Bohne, J., Schmidt, M., Kalle, C. V., Knöß, S., Schambach, A., & Baum, C. (2006) · Blood · doi:10.1182/blood-2005-08-024976 · Cited by 326

Clonal Dominance of Hematopoietic Stem Cells Triggered by Retroviral Gene Marking

Kustikova, O. S., Fehse, B., Modlich, U., Yang, M., Düllmann, J., Kamino, K., Neuhoff, N. V., Schlegelberger, B., Li, Z., & Baum, C. (2005) · Science · doi:10.1126/science.1105063 · Cited by 323

Genotoxicity of Retroviral Integration In Hematopoietic Cells

Nienhuis, A. W., Dunbar, C. E., & Sorrentino, B. P. (2006) · Molecular Therapy · doi:10.1016/j.ymthe.2006.03.001 · Cited by 301

Insertion of myeloid-active elements into the human cytomegalovirus major immediate early promoter is not sufficient to drive its activation upon infection of undifferentiated myeloid cells

Qin, Q., Lee, S. H., Liang, R., & Kalejta, R. F. (2013) · Virology · doi:10.1016/j.virol.2013.10.011 · Cited by 9

Towards in vivo amplification: Overcoming hurdles in the use of hematopoietic stem cells in transplantation and gene therapy.

Nagree, M. S., López-Vásquez, L., & Medin, J. A. (2015) · PubMed · doi:10.4252/wjsc.v7.i11.1233 · Cited by 11

Safety and Efficacy of Retroviral and Lentiviral Vectors for Gene Therapy

Cesana, D., Volpin, M., Secanechia, Y. N. S., & Montini, E. (2017) · Springer eBooks · doi:10.1007/978-3-319-53457-2_2 · Cited by 9

Tracking of Specific Integrant Clones in Dogs Treated with Foamy Virus Vectors

Ohmine, K., Li, Y., Bauer, T. R., Hickstein, D. D., & Russell, D. W. (2010) · Human Gene Therapy · doi:10.1089/hum.2010.072 · Cited by 9

F2A sequence linking MGMTP140K and MDR1 in a bicistronic lentiviral vector enables efficient chemoprotection of haematopoietic stem cells

Maier, P., Heckmann, D., Spier, I., Laufs, S., Zucknick, M., Allgayer, H., Früehauf, S., Zeller, W. J., & Wenz, F. K. (2012) · Cancer Gene Therapy · doi:10.1038/cgt.2012.67 · Cited by 9

IND-Enabling Studies for a Clinical Trial to Genetically Program a Persistent Cancer-Targeted Immune System

Puig-Saus, C., Parisi, G., García-Díaz, Á., Krystofinski, P. E., Sandoval, S., Zhang, R., Champhekar, A. S., McCabe, J. G., Cheung-Lau, G. C., Truong, N. A., et al. (2018) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-18-0963 · Cited by 9

Gene Therapy

Worgall, S., & Crystal, R. G. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-398358-9.00034-3 · Cited by 12

Improving the Assessment of Risk Factors Relevant to Potential Carcinogenicity of Gene Therapies: A Consensus Article

Klapwijk, J. C., Río-Espínola, A. D., Libertini, S., Collin, P., Fellows, M. D., Jobling, S., Lynch, A. M., Martus, H., Vickers, C. A., Zeller, A., et al. (2024) · Human Gene Therapy · doi:10.1089/hum.2024.033 · Cited by 9

Construction of stable producer cells to make high‐titer lentiviral vectors for dendritic cell‐based vaccination

Lee, C.-L., Chou, M., Dai, B., Liang, X., & Wang, P. (2011) · Biotechnology and Bioengineering · doi:10.1002/bit.24413 · Cited by 8

Clonal dynamics studied in cultured induced pluripotent stem cells reveal major growth imbalances within a few weeks

Brenière‐Letuffe, D., Shibamiya, A., Hansen, A., Thomas Eschenhagen, A., Fehse, B., Riecken, K., & Stenzig, J. (2018) · Stem Cell Research & Therapy · doi:10.1186/s13287-018-0893-2 · Cited by 9

Expression of a large coding sequence: Gene therapy vectors for Ataxia Telangiectasia

Hirch, T., Brander, N., Schenk, F., Pollmann, S., Reichenbach, J., Schubert, R., & Modlich, U. (2023) · Scientific Reports · doi:10.1038/s41598-023-46332-4 · Cited by 8

Use of the piggyBac Transposon to Create Stable Packaging Cell Lines for the Production of Clinical-Grade Self-Inactivating γ-Retroviral Vectors

Feldman, S. A., Xu, H., Black, M. A., Park, T. S., Robbins, P. F., Kochenderfer, J. N., Morgan, R. A., & Rosenberg, S. A. (2014) · Human Gene Therapy Methods · doi:10.1089/hgtb.2014.071 · Cited by 8

Cardiomyocyte Progenitor Cells as a Functional Gene Delivery Vehicle for Long-Term Biological Pacing

Végh, A. M. D., den Haan, A. D., Ortega, L. C., Verkerk, A. O., Sluijter, J. P. G., Bakker, D., van Amersfoorth, S. C. M., van Veen, T. A. B., Klerk, M., Seppen, J., et al. (2019) · Molecules · doi:10.3390/molecules24010181 · Cited by 8

Neonatal Intravenous Injection of a Gammaretroviral Vector Has a Low Incidence of Tumor Induction in Mice

Tittiger, M. E., Ma, X., Xu, L., & Ponder, K. P. (2008) · Human Gene Therapy · doi:10.1089/hum.2008.070 · Cited by 8

Improved functionality and potency of next generation BinMLV viral vectors toward safer gene therapy

Looveren, D. V., Giacomazzi, G., Thiry, I., Sampaolesi, M., & Gijsbers, R. (2021) · Molecular Therapy — Methods & Clinical Development · doi:10.1016/j.omtm.2021.07.003 · Cited by 7

Quantification of the dynamics of population heterogeneities in CHO cultures with stably integrated fluorescent markers

Möller, J., Rosenberg, M., Riecken, K., Pörtner, R., Zeng, A., & Jandt, U. (2020) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-020-02401-5 · Cited by 7

Lentiviral vector system for coordinated constitutive and drug controlled tetracycline-regulated gene co-expression

Stahlhut, M., Schwarzer, A., Eder, M., Yang, M., Li, Z., Morgan, M. A., Schambach, A., & Kustikova, O. S. (2015) · Biomaterials · doi:10.1016/j.biomaterials.2015.06.022 · Cited by 7

Tightly regulated ‘all-in-one’ lentiviral vectors for protection of human hematopoietic cells from anticancer chemotherapy

Lachmann, N., Brennig, S., Hillje, R., Schermeier, H., Phaltane, R., Dahlmann, J., Gruh, I., Heinz, N., Schiedlmeier, B., Baum, C., et al. (2015) · Gene Therapy · doi:10.1038/gt.2015.61 · Cited by 7

Genotoxicity Assay for Gene Therapy Vectors in Tumor Prone Cdkn2a−/− Mice

Montini, E., & Cesana, D. (2012) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/b978-0-12-386509-0.00009-0 · Cited by 8

Preclinical development of lentiviral vector gene therapy for Diamond-Blackfan anemia syndrome

Bhoopalan, S. V., Mayuranathan, T., Liu, N., Mayberry, K. D., Yao, Y., Zhang, J., Métais, J., Yan, K., Throm, R. E., Ellis, S. R., et al. (2024) · Molecular Therapy · doi:10.1016/j.ymthe.2024.12.020 · Cited by 7

Human cancer-targeted immunity via transgenic hematopoietic stem cell progeny

Nowicki, T. S., Deen, N. N. A., Peters, C. W., Comı́n-Anduix, B., Medina, E., Puig-Saus, C., Baselga-Carretero, I., Kaplan‐Lefko, P. J., Macabali, M. H., Garcilazo, I. P., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-60816-z · Cited by 6

Analysis of Self-Inactivating Lentiviral Vector Integration Sites and Flanking Gene Expression in Human Peripheral Blood Progenitor Cells After Alkylator Chemotherapy

Grund, N., Maier, P., Giordano, F. A., Appelt, J. U., Zucknick, M., Li, L., Wenz, F. K., Zeller, W. J., Früehauf, S., Allgayer, H., et al. (2010) · Human Gene Therapy · doi:10.1089/hum.2009.116 · Cited by 6

Assessing the Risk of T-cell Malignancies in Mouse Models of SCID-X1

Sorrentino, B. P. (2010) · Molecular Therapy · doi:10.1038/mt.2010.69 · Cited by 6

Transgene Site-Specific Integration: Problems and Solutions

Bire, S., & Rouleux‐Bonnin, F. (2012) · Topics in current genetics · doi:10.1007/978-94-007-4531-5_1 · Cited by 6

Chemoprotection of murine hematopoietic cells by combined gene transfer of cytidine deaminase (CDD) and multidrug resistance 1 gene (MDR1)

Brennig, S., Lachmann, N., Buchegger, T., Hetzel, M., Schambach, A., & Moritz, T. (2015) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-015-0260-4 · Cited by 5

Disclosing the Parameters Leading to High Productivity of Retroviral Producer Cells Lines: Evaluating Random Versus Targeted Integration

Bandeira, V., Tomás, H. A., Alici, E., Carrondo, M. J. T., & Coroadinha, A. S. (2017) · Human Gene Therapy Methods · doi:10.1089/hgtb.2016.149 · Cited by 5

Changing Blue Fluorescent Protein to Green Fluorescent Protein Using Chemical RNA Editing as a Novel Strategy in Genetic Restoration

Vu, L. T., Nguyen, T. T. K., Alam, S., Sakamoto, T., Fujimoto, K., Suzuki, H., & Tsukahara, T. (2015) · Chemical Biology & Drug Design · doi:10.1111/cbdd.12592 · Cited by 5

Was cDNA Sequences Modulate Transgene Expression of Was Promoter-Driven Lentiviral Vectors

Toscano, M. G., Benabdellah, K., Muñoz, P., Frecha, C. A., Cobo, M., & Martı́n, F. (2009) · Human Gene Therapy · doi:10.1089/hum.2009.118 · Cited by 5

Quest for safety at AAValon

Montini, E. (2011) · Blood · doi:10.1182/blood-2011-02-321984 · Cited by 5

Chemoprotection by Transfer of Resistance Genes

Budak-Alpdoǧan, T., & Bertino, J. R. (2009) · Methods in molecular biology · doi:10.1007/978-1-59745-561-9_34 · Cited by 5

Meta-Analysis and Optimization of the In Vitro Immortalization Assay for Safety Assessment of Retroviral Vectors in Gene Therapy

Bastone, A. L., John-Neek, P., Dziadek, V., Mansel, F., Hagedorn, M., Fleischauer, J., Weigel, B., Paul, G., Schambach, A., & Rothe, M. (2025) · Human Gene Therapy · doi:10.1089/hum.2024.221 · Cited by 4

TALEN-mediated intron editing of HSPCs enables transgene expression restricted to the myeloid lineage

Seclén, E., Jang, J. C., Lawal, A. O., Pulicani, S., Boyne, A. R., Tkach, D., Juillerat, A., Duchateau, P. N., & Valton, J. (2024) · Molecular Therapy · doi:10.1016/j.ymthe.2024.04.001 · Cited by 4

Monitoring for Potential Adverse Effects of Prenatal Gene Therapy: Genotoxicity Analysis In Vitro and on Small Animal Models Ex Vivo and In Vivo

Themis, M. (2012) · Methods in molecular biology · doi:10.1007/978-1-61779-873-3_16 · Cited by 4

Retrovirus mediated hematopoietic gene therapy: A European regulatory perspective with special focus on the situation in Germany

Voelkel, C., Lührmann, A., Baum, C., & von der Leyen, H. E. (2010) · CyberLeninK (CyberLeninka) · Cited by 4

The cHS4 Chromatin Insulator Reduces the Rate of Retroviral Vector-Mediated Gene Dysregulation Associated with Aberrant Vector Transcription

Zhou, X., Liu, Q., Wang, D., Zhang, X., Emery, D. W., & Li, C. L. (2017) · Cytogenetic and Genome Research · doi:10.1159/000464315 · Cited by 3

Gene delivery using AAV8 in vivo for disease stabilization in a bimodal gene therapy approach for the treatment of ADA-deficient SCID

Carbonaro-Sarracino, D. A., Chun, K. M., Clark, D. N., Kaufman, M. L., Jin, X., Wang, X., & Kohn, D. B. (2021) · Molecular Therapy — Methods & Clinical Development · doi:10.1016/j.omtm.2021.02.007 · Cited by 3

T-cell neoplasias and secondary malignancies after CAR-T cell therapy: current knowledge, risk factors, and implications from CAR-T engineering strategies

Maurer, K., & Jacobson, C. (2025) · Leukemia and Lymphoma · doi:10.1080/10428194.2025.2460043 · Cited by 4

Development of gene therapy: potential in severe combined immunodeficiency due to adenosine deaminase deficiency

Montiel-Equihua, C., Thrasher, A. J., & Gaspar, H. B. (2009) · Stem Cells and Cloning Advances and Applications · doi:10.2147/sccaa.s5570 · Cited by 3

Recent Advances and Improvements in the Biosafety of Gene Therapy

Sivalingam, J., & Lian, O. (2011) · InTech eBooks · doi:10.5772/21733 · Cited by 3

Gene Therapy for Erythroid Metabolic Inherited Diseases

García-Gómez, M., Bustamante, O. Q., García, M., Navarro, S., Garate, Z., & Jose, C. (2013) · InTech eBooks · doi:10.5772/52531 · Cited by 2

Properties of Mesenchymal Stem Cells to Consider for Cancer Cell Therapy

Stagg, J., & Pommey, S. (2009) · Springer eBooks · doi:10.1007/978-90-481-3040-5_5 · Cited by 2

Insertional Mutagenesis in Hematopoietic Cells: Lessons Learned from Adverse Events in Clinical Gene Therapy Trials

Müller, L., Milsom, M. D., & Williams, D. A. (2010) · Springer eBooks · doi:10.1007/978-1-4419-7656-7_6 · Cited by 2

Lentiviral Gene Therapy of Chronic Granulomatous Disease: Functional Assessment of Universal and Tissue-Specific Promoters

Yuan, H.-K., Wu, X., Liu, H., & Chang, L. (2022) · Human Gene Therapy · doi:10.1089/hum.2022.140 · Cited by 2

Long Terminal Repeats of Gammaretroviruses Retain Stable Expression after Integration Retargeting

Miklík, D., Slavková, M., Kučerová, D., Mekadim, C., Mrázek, J., & Hejnar, J. (2024) · Viruses · doi:10.3390/v16101518 · Cited by 2

Development of murine leukemia virus-based retroviral vectors with a minimum possibility of cis-activation

Jang, J., Lee, J.-T., Lee, K., Kim, S., Kim, S., Yoon, K., & Kim, S. (2010) · Gene Therapy · doi:10.1038/gt.2010.135 · Cited by 2

Retroviral Integration Target Site Selection

Ciuffi, A., & Bushman, F. D. (2011) · Wiley eBooks · doi:10.1002/9781118015377.ch5 · Cited by 2

Therapeutic antibody delivery: vector tools to boost efficacy and affordability

Chiyyeadu, A., Khan, B., Ehrhardt, K., Büning, H., Morgan, M. A., & Schambach, A. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1714390 · Cited by 1

Clinical Grade Lentiviral Vectors

Kochan, G. T., Escors, D., Stephenson, H. N., & Breckpot, K. (2012) · SpringerBriefs in biochemistry and molecular biology · doi:10.1007/978-3-0348-0402-8_5 · Cited by 2

Gene Therapy in the Clinics: Shifting Into the Next Gear

Ogris, M. (2013) · Therapeutic Delivery · doi:10.4155/tde.13.109 · Cited by 1

Regulated promoters

Geurts, J., van den Berg, W. B., & van de Loo, F. A. J. (2010) · Springer eBooks · doi:10.1007/978-3-0346-0165-8_10 · Cited by 1

Gene Therapy of Liver Disease with Lentiviral Vectors Preclinical Studies in Models of Crigler-Najjar Disease and Hepatitis C

van der Wegen, P. (2009)

Intracellular Expression of Peptides

Wichmann, C. W., Becker, Y., & Grez, M. (2009) · doi:10.1002/9783527626830.ch6

MURINE PGK PROMOTER IN A LENTIVIRAL VECTOR IN CANINE LEUKOCYTE ADHESION DEFICIENCY AND IN HUMAN LAD-1 CD34 + CELLS IN NSG MICE

Hunter, M. J., Choi, U., Tuschong, L. M., Zhao, H., Koontz, S. M., Kapoor, V., Persons, D. A., Malech, H. L., & Hickstein, D. D. (2012) · Gene Therapy and Regulation · doi:10.1142/s156855861250001x

Desarrollo de vectores lentivirales para terapia génica del síndrome de Hiper-IgM ligado al cromosoma X (X-HIGM1)

Romero, Z. G. (2009) · Institutional Repository of the University of Granada (University of Granada)

Cell-Based Gene Therapy

Geiger, S. (2015) · WORLD SCIENTIFIC eBooks · doi:10.1142/9789814616799_0014

Gene Therapy for Primary Immune Deficiencies

Kohn, D. B. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-405546-9.00059-5

Non-invasive nanosensor monitoring of mRNA expression for regenerative medicine application

Wiraja, C. (2017) · doi:10.32657/10356/72855

Foamy virus vector integration and application in gene therapy

Sweeney, N. P. (2015) · Spiral (Imperial College London) · doi:10.25560/50704

Gene Therapy for Nonmalignant Hematology

Wang, X., & Rivière, I. (2018) · Advances and controversies in hematopoietic transplantation and cell therapy · doi:10.1007/978-3-319-54368-0_14

HEMATOPOIETIC STEM CELL GENE THERAPY FOR INHERITED MONOGENIC DISEASES AND ITS IMPLICATIONS FOR FUTURE GENE THERAPY TRIALS IN TURKEY

Aerts‐Kaya, F., Güney-Esken, G., & Erol, Ö. D. (2019) · Trakya University Journal of Natural Sciences · doi:10.23902/trkjnat.483402

Gene therapy

Rivat, C., Thrasher, A. J., & Gaspar, H. B. (2013) · Elsevier eBooks · doi:10.1016/b978-0-7234-3691-1.00099-4

494. Hematopoietic Stem Cell Gene Therapy for Cystinosis

(2013) · Molecular Therapy · doi:10.1016/s1525-0016(16)34829-8

Hematopoietic Stem Cell Gene Therapy Alleviates Disease Phenotypes in a Murine Model of Danon DiseasePreprint

Chen, C., Hashem, S. I., Sharma, J., Manso, A. M., Bushway, P., Duran, J. M., Gault, E. C., Gu, Y., Nigenda, J. R. C., Soto‐Hermida, A., et al. (2022) · Research Square · doi:10.21203/rs.3.rs-1921280/v1

Long Terminal Repeats of Gammaretroviruses Retain Stable Expression After Integration Retargeting or Knock-In into the Restrictive Chromatin of Lamina-Associated DomainsPreprint

Miklík, D., Slavková, M., Kučerová, D., Mekadim, C., Mrázek, J., & Hejnar, J. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.05.30.596639

Clinic viral diagnostics, viral vaccines, and advanced immunology

Upreti, S., & Samant, M. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-15241-2.00007-7

Dyskeratosis congenita future: Hematopoietic stem cell transplantation or gene therapy?

Manoochehrabadi, S., Behfar, M., Ahmadvand, M., & Hamidieh, A. A. (2024) · Gene Reports · doi:10.1016/j.genrep.2024.102072

Short-Term Follow-Up Study on the Efficacy and Safety of Intravitreal Bevacizumab for Macular Edema Secondary to Retinal Venous Occlusions

Kandukuri, R., Lakshmi, S., & Kanth, V. D. (2025) · Cureus · doi:10.7759/cureus.88773

Enhanced transcriptional insulation of lentiviral vectors using “sequence-upgraded polyA long terminal repeats” or “supA-LTRs”

Wright, J., Alberts, B. M., Quiles, M. L. M., Guarino, A., Chipchase, D., Clarkson, N. G., Mitrophanous, K. A., & Farley, D. C. (2025) · Molecular Therapy Advances · doi:10.1016/j.omta.2025.201654

Optimisation de la biosécurité du vecteur transposon piggyBac pour le transfert de gène : utilisation des ARN messagers et des insulateurs.

Bire, S. (2011) · theses.fr (ABES) · doi:10.70675/d08a1dbaz7701z4841zb7fczb5ce3a066e87

Optimisation de la stratégie de thérapie génique par vecteur lentiviral pour la β-thalassémie

Giorgi, M. (2019) · theses.fr (ABES) · doi:10.70675/041f272dz23faz452bzb352z46cf95acb76d

Development and application of non-integrating lentiviral vectors for gene therapy

Apolonia, L. (2009) · UCL Discovery (University College London)

Cell-culture assays reveal the importance of retroviral vector design for insertional genotoxicity

Modlich, U., Bohne, J., Schmidt, M., Kalle, C. V., Knöß, S., Schambach, A., & Baum, C. (2006) · Blood · doi:10.1182/blood-2005-08-024976 · Cited by 326

Promoters and insulators: creating a safer integrating vector

Weber, E. L. (2015) · University of Southern California Digital Library · doi:10.25549/usctheses-m587

Insertional Transformation of Hematopoietic Cells by Self-inactivating Lentiviral and Gammaretroviral Vectors

Modlich, U., Navarro, S., Zychlinski, D., Maetzig, T., Knoess, S., Brugman, M. H., Schambach, A., Charrier, S., Galy, A., Thrasher, A. J., et al. (2009) · Molecular Therapy · doi:10.1038/mt.2009.179 · Cited by 387

Transcriptional Enhancers Induce Insertional Gene Deregulation Independently From the Vector Type and Design

Maruggi, G., Porcellini, S., Facchini, G., Perna, S. K., Cattoglio, C., Sartori, D., Ambrosi, A., Schambach, A., Baum, C., Bonini, C., et al. (2009) · Molecular Therapy · doi:10.1038/mt.2009.51 · Cited by 81

Uncovering and Dissecting the Genotoxicity of Self-inactivating Lentiviral Vectors In Vivo

Cesana, D., Ranzani, M., Volpin, M., Bartholomae, C., Duros, C., Artus, A., Merella, S., Benedicenti, F., Sergi Sergi, L., Sanvito, F., et al. (2014) · Molecular Therapy · doi:10.1038/mt.2014.3 · Cited by 189