The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Rapid lentiviral transduction preserves the engraftment potential of Fanca(−/−) hematopoietic stem cells
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The success of gene therapy approaches to FA in a clinical setting has been limited by a combination of factors, including the paucity of autologous CD34+ cells available as targets for gene correction, reservations about the use of cytoreductive therapy to “make space” for the autologous graft, and potentially defective engraftment of FA HSC following prolonged in vitro processing[33–35].”
From Finding the needle in the hay stack: Hematopoietic stem cells in Fanconi anemia (2009) · cites this paper as [33]
In the citing paper
“We demonstrated significantly enhanced engraftment of transduced long term repopulating HSCs following rapid lentiviral transduction transduction[33].”
From Finding the needle in the hay stack: Hematopoietic stem cells in Fanconi anemia (2009) · cites this paper as [33]
In the citing paper
“Ex vivo gene transfer into HSC of gene targeted FA mice has been shown to correct the cellular FA phenotype at the level of long term repopulating stem cells [33,60–62].”
From Finding the needle in the hay stack: Hematopoietic stem cells in Fanconi anemia (2009) · cites this paper as [33]
In the citing paper
“We recently reported the advantages of rapid lentiviral over conventional gammaretroviral transduction in a murine model of FA type A[33].”
From Finding the needle in the hay stack: Hematopoietic stem cells in Fanconi anemia (2009) · cites this paper as [33]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Stem Cell Collection and Gene Transfer in Fanconi Anemia
Kelly, P. F., Radtke, S., Kalle, C. V., Balcik, B., Bohn, K., Mueller, R., Schuesler, T., Haren, M., Reeves, L., Cancelas, J. A., et al. (2007) · Molecular Therapy · doi:10.1038/sj.mt.6300033 · Cited by 180
Self-citation
Research works printed but not linked: 45
- Taniguchi, 2006, Molecular pathogenesis of Fanconi anemia: recent progress, Blood, 107, 4223, 10.1182/blood-2005-10-4240 · DOI
- Smogorzewska, 2007, Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair, Cell, 129, 289, 10.1016/j.cell.2007.03.009 · DOI
- Kutler, 2003, A 20-year perspective on the International Fanconi Anemia Registry (IFAR), Blood, 101, 1249, 10.1182/blood-2002-07-2170 · DOI · Paper page
- Rosenberg, 2005, Risk of head and neck squamous cell cancer and death in patients with Fanconi anemia who did and did not receive transplants, Blood, 105, 67, 10.1182/blood-2004-04-1652 · DOI
- Farzin, 2007, Matched sibling donor haematopoietic stem cell transplantation in Fanconi anaemia: an update of the Cincinnati Children's experience, Br J Haematol, 136, 633, 10.1111/j.1365-2141.2006.06460.x · DOI · Paper page
- Wagner, 2007, Unrelated donor bone marrow transplantation for the treatment of Fanconi anemia, Blood, 109, 2256, 10.1182/blood-2006-07-036657 · DOI · Paper page
- Liu, 1997, Retroviral mediated gene transfer of the Fanconi anemia complementation group C gene to hematopoietic progenitors of group C patients, Hum Gene Ther, 8, 1715, 10.1089/hum.1997.8.14-1715 · DOI
- Yamada, 2003, Phenotype correction of Fanconi anemia group A hematopoietic stem cells using lentiviral vector, Mol Ther, 8, 600, 10.1016/S1525-0016(03)00223-5 · DOI · Paper page
- Galimi, 2002, Gene therapy of Fanconi anemia: preclinical efficacy using lentiviral vectors, Blood, 100, 2732, 10.1182/blood-2002-04-1245 · DOI · Paper page
- Rio, 2002, In vitro phenotypic correction of hematopoietic progenitors from Fanconi anemia group A knockout mice, Blood, 100, 2032, 10.1182/blood.V100.6.2032 · DOI
- Liu, 1999, Engraftment of hematopoietic progenitor cells transduced with the Fanconi anemia group C gene (FANCC), Hum Gene Ther, 10, 2337, 10.1089/10430349950016988 · DOI · Paper page
- Li, 2005, Ex vivo culture of Fancc−/− stem/progenitor cells predisposes cells to undergo apoptosis, and surviving stem/progenitor cells display cytogenetic abnormalities and an increased risk of malignancy, Blood, 105, 3465, 10.1182/blood-2004-06-2483 · DOI · Paper page
- Miller, 1990, Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection, Mol Cell Biol, 10, 4239, 10.1128/MCB.10.8.4239 · DOI · Paper page
- Reiser, 1996, Transduction of nondividing cells using pseudotyped defective high- titer HIV type 1 particles, Proc Natl Acad Sci USA, 93, 15266, 10.1073/pnas.93.26.15266 · DOI · Paper page
- Kurre, 2006, Rapid 1-hour transduction of whole bone marrow leads to long-term repopulation of murine recipients with lentivirus-modified hematopoietic stem cells, Gene Ther, 13, 369, 10.1038/sj.gt.3302659 · DOI
- Mostoslavsky, 2005, Efficiency of transduction of highly purified murine hematopoietic stem cells by lentiviral and oncoretroviral vectors under conditions of minimal in vitro manipulation, Mol Ther, 11, 932, 10.1016/j.ymthe.2005.01.005 · DOI
- Cheng, 2000, Mice with a targeted disruption of the Fanconi anemia homolog Fanca, Hum Mol Genet, 9, 1805, 10.1093/hmg/9.12.1805 · DOI · Paper page
- Haneline, 1999, Loss of FancC function results in decreased hematopoietic stem cell repopulating ability, Blood, 94, 1, 10.1182/blood.V94.1.1.413k03_1_8 · DOI
- Navarro, 2006, Hematopoietic dysfunction in a mouse model for Fanconi anemia group D1, Mol Ther, 14, 525, 10.1016/j.ymthe.2006.05.018 · DOI
- Xu-Welliver, 1998, Isolation of human O6-alkylguanine-DNA alkyltransferase mutants highly resistant to inactivation by O6-benzylguanine, Cancer Res, 58, 1936
- Zielske, 2003, In vivo selection of MGMT(P140K) lentivirus-transduced human NOD/SCID repopulating cells without pretransplant irradiation conditioning, J Clin Invest, 112, 1561, 10.1172/JCI200317922 · DOI
- Sawai, 2001, Protection and in vivo selection of hematopoietic stem cells using temozolomide, O6-benzylguanine, and an alkyltransferase-expressing retroviral vector, Mol Ther, 3, 78, 10.1006/mthe.2000.0223 · DOI
- Ragg, 2000, Direct reversal of DNA damage by mutant methyltransferase protein protects mice against dose-intensified chemotherapy and leads to in vivo selection of hematopoietic stem cells, Cancer Res, 60, 5187
- Milsom, 2007, Live and let die: in vivo selection of gene-modified hematopoietic stem cells via MGMT-mediated chemoprotection, DNA Repair (Amst), 6, 1210, 10.1016/j.dnarep.2007.03.020 · DOI
- Chandra, 2005, A rapid method for retrovirus-mediated identification of complementation groups in Fanconi anemia patients, Mol Ther, 12, 976, 10.1016/j.ymthe.2005.04.021 · DOI
- Gross, 2002, Reverse mosaicism in Fanconi anemia: natural gene therapy via molecular self-correction, Cytogenet Genome Res, 98, 126, 10.1159/000069805 · DOI · Paper page
- Gregory, 2001, Somatic mosaicism in Fanconi anemia: evidence of genotypic reversion in lymphohematopoietic stem cells, Proc Natl Acad Sci USA, 98, 2532, 10.1073/pnas.051609898 · DOI
- Freie, 1996, Correction of Fanconi anemia type C phenotypic abnormalities using a clinically suitable retroviral vector infection protocol, Cell Transplant, 5, 385, 10.1016/0963-6897(95)02022-5 · DOI
- Haneline, 2003, Retroviral-mediated expression of recombinant Fancc enhances the repopulating ability of Fancc−/− hematopoietic stem cells and decreases the risk of clonal evolution, Blood, 101, 1299, 10.1182/blood-2002-08-2404 · DOI
- Cavazzana-Calvo, 2000, Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease, Science, 288, 669, 10.1126/science.288.5466.669 · DOI · Paper page
- Gaspar, 2004, Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped γ-retroviral vector, Lancet, 364, 2181, 10.1016/S0140-6736(04)17590-9 · DOI
- Aiuti, 2002, Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning, Science, 296, 2410, 10.1126/science.1070104 · DOI · Paper page
- Neff, 2005, Polyclonal chemoprotection against temozolomide in a large-animal model of drug resistance gene therapy, Blood, 105, 997, 10.1182/blood-2004-08-3169 · DOI
- Li, 2004, Continuous in vivo infusion of interferon-γ (IFN-γ) preferentially reduces myeloid progenitor numbers and enhances engraftment of syngeneic wild-type cells in Fancc−/− mice, Blood, 104, 1204, 10.1182/blood-2004-03-1094 · DOI
- Si, 2006, Continuous in vivo infusion of interferon-γ (IFN-γ) enhances engraftment of syngeneic wild-type cells in Fanca−/− and Fancg−/− mice, Blood, 108, 4283, 10.1182/blood-2006-03-007997 · DOI
- Cattoglio, 2007, Hot spots of retroviral integration in human CD34+ hematopoietic cells, Blood, 110, 1770, 10.1182/blood-2007-01-068759 · DOI
- Dull, 1998, A third-generation lentivirus vector with a conditional packaging system, J Virol, 72, 8463, 10.1128/JVI.72.11.8463-8471.1998 · DOI · Paper page
- Schambach, 2006, Equal potency of γ-retroviral and lentiviral SIN vectors for expression of O6-methylguanine-DNA methyltransferase in hematopoietic cells, Mol Ther, 13, 391, 10.1016/j.ymthe.2005.08.012 · DOI
- Schambach, 2006, Woodchuck hepatitis virus post-transcriptional regulatory element deleted from X protein and promoter sequences enhances retroviral vector titer and expression, Gene Ther, 13, 641, 10.1038/sj.gt.3302698 · DOI
- Crone, 1994, Mutations in human O6-alkylguanine-DNA alkyltransferase imparting resistance to O6-benzylguanine, Cancer Res, 54, 6221
- Naldini, 1996, In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector, Science, 272, 263, 10.1126/science.272.5259.263 · DOI · Paper page
- Geiger, 1998, Globin gene expression is reprogrammed in chimeras generated by injecting adult hematopoietic stem cells into mouse blastocysts, Cell, 93, 1055, 10.1016/S0092-8674(00)81210-6 · DOI
- Hanenberg, 1996, Colocalization of retrovirus and target cells on specific fibronectin fragments increases genetic transduction of mammalian cells, Nat Med, 2, 876, 10.1038/nm0896-876 · DOI
- Villella, 2005, Real-time PCR: an effective tool for measuring transduction efficiency in human hematopoietic progenitor cells, Mol Ther, 11, 483, 10.1016/j.ymthe.2004.10.017 · DOI
- Will, 2007, Importance of murine study design for testing toxicity of retroviral vectors in support of phase I trials, Mol Ther, 15, 782, 10.1038/sj.mt.6300083 · DOI
Cited by
Finding the needle in the hay stack: Hematopoietic stem cells in Fanconi anemia
Müller, L. U. W., & Williams, D. A. (2009) · Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis · doi:10.1016/j.mrfmmm.2009.03.010 · Cited by 31
Self-citationLeukemic survival factor SALL4 contributes to defective DNA damage repair
Wang, F., Gao, C., Lu, J., Tatetsu, H., Williams, D. A., Müller, L. U., Cui, W., & Chai, L. (2016) · Oncogene · doi:10.1038/onc.2016.146 · Cited by 17
Self-citation
Metadata
- Authors
- Müller, L. U., Milsom, M. D., Kim, M.-O., Schambach, A., Schuesler, T., & Williams, D. A.
- Venue
- Molecular Therapy
- Publisher
- Elsevier BV
- Published
- 2008-06
- Volume
- 16
- Issue
- 6
- Pages
- 1154-1160
- ISSN
- 1525-0016
- Cited by
- 32
- References
- 1
- Language
- en
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review