Zinc-finger nucleases as a novel therapeutic strategy for targeting hepatitis B virus DNAs

Cradick, Thomas J, Keck, Kathy, Bradshaw, Shannon, Jamieson, Andrew C, McCaffrey, Anton P·2010·Molecular Therapy

Cited by (185)

Items 101–185 of 185

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  2. Zinc finger nucleases: Tailor-made for gene therapy
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  3. HER2+ Breast Cancer Therapy: By CPP-ZFN Mediated Targeting of mTOR?
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  4. Chronic hepatitis B: Are we close to a cure?
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  5. Neuroprotective therapies in glaucoma: II. Genetic nanotechnology tools
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  6. Interplay between hepatitis B virus and the innate immune responses: implications for new therapeutic strategies
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  8. Advances in Nanoparticle Drug Delivery Systems for Anti-Hepatitis B Virus Therapy: A Narrative Review
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  9. Genome editing technologies to fight infectious diseases
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  10. CRISPR/Cas9 and Genome Editing for Viral Disease—Is Resistance Futile?
    Harshana S. De Silva Feelixge, Daniel Stone, Pavitra Roychoudhury, Martine Aubert, Keith R. Jerome · 2018 · ACS Infectious Diseases
  11. Novel therapeutic approaches for hepatitis B virus covalently closed circular DNA
    Motoko Ohno, Motoyuki Otsuka, Takahiro Kishikawa, Takeshi Yoshikawa, Akemi Takata, Kazuhiko Koike · 2015 · World Journal of Gastroenterology
  12. Eradication Strategies for Chronic Hepatitis B Infection
    Eleanor M. P. Wilson, Lydia Tang, Shyam Kottilil · 2016 · Clinical Infectious Diseases
  13. Genome Engineering in Human Cells
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  14. A T7 Endonuclease I Assay to Detect Talen-Mediated Targeted Mutation of HBV cccDNA
    Kristie M. Bloom, Abdullah Ely, Patrick B. Arbuthnot · 2016 · Methods in molecular biology
  15. Persistence of Hepatitis B Virus Infection: A Multi-Faceted Player for Hepatocarcinogenesis
    Suchandrima Ghosh, Anannya Chakraborty, Soma Banerjee · 2021 · Frontiers in Microbiology
  16. Epigenetic regulation of covalently closed circular DNA minichromosome in hepatitis B virus infection
    Zhaoning Wang, Weiwei Wang, Lanfeng Wang · 2020 · Biophysics Reports
  17. Identity of zinc finger nucleases with specificity to herpes simplex virus type II genomic DNA: Novel HSV-2 vaccine/therapy precursors
    Wayengera, Misaki · 2011 · Theoretical Biology and Medical Modelling
  18. Search for a cure for chronic hepatitis B infection: How close are we?
    Wah Wah Phyo · 2015 · World Journal of Hepatology
  19. Gene therapeutic approaches to inhibit hepatitis B virus replication
    Maren Gebbing · 2014 · World Journal of Hepatology
  20. Transcription Activator-Like Effector (TALE) Nucleases and Repressor TALEs for Antiviral Gene Therapy
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  21. Research progress in hepatitis B virus covalently closed circular DNA
    Xiaodong Zhang, Yufei Wang, Guang Yang · 2021 · Cancer Biology and Medicine
  22. Role of hepatitis B virus in development of hepatocellular carcinoma: Focus on covalently closed circular DNA
    Claryssa Bianca, Elizabeth Sidhartha, Claudio Tiribelli, Korri Elvanita El-Khobar, Caecilia Hapsari Ceriapuri Sukowati · 2022 · World Journal of Hepatology
  23. High-Throughput Cellular Screening of Engineered Nuclease Activity Using the Single-Strand Annealing Assay and Luciferase Reporter
    Thomas James Cradick, Christopher J. Antico, Gang Bao · 2014 · Methods in molecular biology
  24. Recent developments with advancing gene therapy to treat chronic infection with hepatitis B virus
    Mohube Betty Maepa, Ridhwaanah Jacobs, Fiona T. van den Berg, Patrick B. Arbuthnot · 2020 · Current Opinion in HIV and AIDS
  25. Antiviral therapy of persistent viral infection using genome editing
    Frank Buchholz, Joachim Hauber · 2016 · Current Opinion in Virology
  26. New directions in hepatitis B therapy research
    Marta Lewandowska, Anna Piekarska · 2017 · Clinical and Experimental Hepatology
  27. Genome Editing with Crispr-Cas9 Systems: Basic Research and Clinical Applications
    Anna Meiliana, Nurrani Mustika Dewi, Andi Wijaya · 2017 · The Indonesian Biomedical Journal
  28. Antiviral Activities of Zn2+ Ions for Viral Prevention, Replication, Capsid Protein in Intracellular Proliferation of Viruses
    Tsuneo Ishida · 2018 · World Scientific News
  29. New Treatment Options in Chronic Hepatitis B: How Close Are We to Cure?
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  30. Genomic medicine in hepatology: mechanisms and liver treatment strategies
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  31. Hepatitis B Virus
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  32. Targeting Hepatitis B Virus DNA Using Designer Gene Editors
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  33. Hepatitis B Virus Epsilon (ε) RNA Element: Dynamic Regulator of Viral Replication and Attractive Therapeutic Target
    Lukasz T. Olenginski, Solomon K. Attionu, Erica N. Henninger, Regan M. LeBlanc, Andrew P. Longhini, Theodore Kwaku Dayie · 2023 · Viruses
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    Sudhanshu P. Raikwar, Apoorva S Raikwar, Shyam Sunder Chaurasia, Rajiv R. Mohan · 2016 · World Journal of Translational Medicine
  35. TALENs Targeting HBV: Designer Endonuclease Therapies for Viral Infections
    Nicholas D. Weber, Daniel Stone, Keith R. Jerome · 2013 · Molecular Therapy
  36. Molecular epidemiology of hepatitis B virus (HBV) in Ethiopia: A review article
    Ayenew Assefa, Molla Getie, Birhanu Getie, Taklo Simeneh Yazie, Aklesya Enkobahry · 2024 · Infection Genetics and Evolution
  37. Prospects of viral vector-mediated delivery of sequences encoding anti-HBV designer endonucleases
    Ridhwaanah Jacobs, Prashika Singh, Tiffany S. Smith, Patrick B. Arbuthnot, Mohube Betty Maepa · 2022 · Gene Therapy
  38. Recent Advances in Developing Nucleic Acid-Based HBV Therapy
    Musa D. Marimani, Justin Hean, Kristie M. Bloom, Abdullah Ely, Patrick B. Arbuthnot · 2013 · Future Microbiology
  39. Liver transplantation and hepatitis B virus infection
    Albert C. Y. Chan, James Fung, Chung Mau Lo · 2016 · Current Opinion in Organ Transplantation
  40. Novel therapies and potential therapeutic targets in the management of chronic hepatitis B
    Joao M. Serigado, Manhal J. Izzy, Harmit S. Kalia · 2017 · European Journal of Gastroenterology & Hepatology
  41. DNA Detection Technology Using Zinc Finger Protein
    Takenori Kumagai Koichi Abe, Wataru Yoshida · 2015 · Journal of Microbial & Biochemical Technology
  42. Recent advances in therapeutic recruitment of mammalian RNAi and bacterial CRISPR-Cas DNA interference pathways as emerging antiviral strategies
    Wei-Xin Chin, Swee Kim Ang, Justin Jang Hann Chu · 2016 · Drug Discovery Today
  43. Meganucleases and Their Biomedical Applications
    Rafael Molina, Guillermo Montoya, Jesús Prìeto · 2011 · Encyclopedia of Life Sciences
  44. Progress and prospects of engineered sequence-specific DNA modulating technologies for the management of liver diseases
    Samantha Nicholson · 2015 · World Journal of Hepatology
  45. Engineered Meganucleases for Genome Engineering Purposes
    Jean Charles Epinat, George H. Silva, Frédéric Pâques, Julianne N. P. Smith, Philippe N. Duchateau · 2012 · Topics in current genetics
  46. Meganuclease-mediated Virus Self-cleavage Facilitates Tumor-specific Virus Replication
    Engin Gürlevik, Peter Schache, Anneliese Goez, Arnold Kloos, Norman Woller, Nina Armbrecht, Michael Peter Manns, Stefan Kubicka, Florian Kühnel · 2013 · Molecular Therapy
  47. Engineering Sequence-Specific DNA Binding Proteins for Antiviral Gene Editing
    Patrick B. Arbuthnot · 2015 · Elsevier eBooks
  48. Inhibitor-Based Therapeutics for Treatment of Viral Hepatitis
    Debajit Dey, Manidipa Banerjee · 2016 · Journal of Clinical and Translational Hepatology
  49. Recent Advances in Use of Gene Therapy to Treat Hepatitis B Virus Infection
    Kristie M. Bloom, Abdullah Ely, Patrick B. Arbuthnot · 2015 · Advances in experimental medicine and biology
  50. Extrachromosomal Circular DNA: A Mobile Genetic Element Shaping Host Biology
    Shun Yao, Oliver W. Chung, Ling Wang, ZZ Zhao Zhang · 2025 · Annual Review of Cell and Developmental Biology
  51. Disrupting Viral Persistence: CRISPR /Cas9‐Based Strategies for Hepatitis B and C Treatment, and Challenges
    Meng‐Fan Li, Akmal Zubair, Safa Wdidi, Shan He · 2026 · Journal of Cellular and Molecular Medicine
  52. Overview of gene editing strategies against HBV
    Zak T. Janetzki, Laura C. McCoullough, Peter A. Revill, Margaret Littlejohn · 2026 · Antiviral Research
  53. AAV Immunotoxicity: Implications in Anti-HBV Gene Therapy
    Ridhwaanah Jacobs, Dennis Makafui Dogbey, Njabulo Mnyandu, Keila Neves, Stefan Barth, Patrick B. Arbuthnot, Mohube Betty Maepa · 2023 · Microorganisms
  54. Genome editing for the treatment of tumorigenic viral infections and virus-related carcinomas
    Lan Yu, Xun Tian, Chun Gao, Ping Wu, Liming Wang, Bei Feng, Xiaomin Li, Hui Wang, Ding Ma, Zheng Hu · 2018 · Frontiers of Medicine
  55. From bench to bedside: stem cell therapy as a transformative approach against HIV
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  56. Treatment of infectious diseases by in vivo gene editing
    Yuxuan Wu, Haokun Zhang · 2023 · National Science Open
  57. Lipid Nanoparticle-Encapsulated TALEN-Encoding mRNA Inactivates Hepatitis B Virus Replication in Cultured Cells and Transgenic Mice
    Tiffany S. Smith, Prashika Singh, Ridhwaanah Bhana, Dylan Kairuz, Kristie M. Bloom, Mohube Betty Maepa, Abdullah Ely, Patrick B. Arbuthnot · 2025 · Viruses
  58. Genome editing with programmable site-specific nucleases
    Takashi Yamamoto, Naoaki Sakamoto, Tetsushi Sakuma · 2014 · Uirusu
  59. Tratamiento actual y nuevas terapias contra la infección crónica por el virus de la Hepatitis B
    Simón Gallo Echeverri, César Caraballo, Mateo Orozco Marín, Octavio Germán Muñoz · 2017 · Revista Colombiana de Gastroenterología
  60. Perspectives of TLR2 agonist use in the road map to HBV cure.
    R. Pieterman, D. Durantel, Hla Janssen, D. Sprengers, S. Buschow · 2026 · Antiviral Research
  61. Bio-applications Derived from Site-Directed Genome Modification Technologies
    Christophe Delenda, Sébastien Paris, Sylvain Arnould, Edward Balbirnie, Jean‐Pierre Cabaniols · 2012 · Topics in current genetics
  62. Cellular Therapies: Gene Editing and Next-Gen CAR T Cells
    Thomas James Cradick · 2016 · Springer eBooks
  63. AVANÇOS NA TERAPIA GENÉTICA PARA TRATAMENTO DE DOENÇAS HEREDITÁRIAS
    Camilla Radimack Santos de Souza, Anna Beatriz Alcântara de Azevêdo Silva, Victória Maso Panassol, Ellis Neide Alves Carneiro, Gabriel Corsino de Paula, João Victor Freitas do Nascimento, Ana Carolina Messias de Souza Ferreira da Costa, Edenilze Teles Romeiro, Ana Paula Pancere Sandre, Rodrigo Rodrigues Damas Filho · 2023 · Revista Ibero-Americana de Humanidades, Ciências e Educação
  64. Gene Therapy and Gene Editing
    Niloofar Bazazzadegan, Mandana Hasanzad, Seyedeh Sedigheh Abedini · 2024 · Springer eBooks
  65. The role of the enzyme systems of the organism in the development of chronic liver diseases
    В. А. Прищепенко, G. I. Yupatov, В. К. Окулич · 2018 · Russian Journal of Evidence-Based Gastroenterology
  66. Application of Gene-Editing Technologies in Embryos and Their Potential for Gene Therapy
    Cristina Eguizábal, Núria Montserrat, Juan Carlos Izpisúa Belmonte · 2018 · Elsevier eBooks
  67. HBV Polymerase as a Target for Development of Anti-HBV Drugs
    S.B. Bhise · 2018 · Elsevier eBooks
  68. HBV enfeksiyonunun tedavisinde CRISPR / Cas9 gen düzenleme sisteminin kullanımı
    Medine Karadag Alpaslan · 2020 · Gene Editing
  69. Virology and Pathogenesis of Hepatitis B
    Antonio Bertoletti, Julie Lucifora, Fabien Zoulim · 2018 · Elsevier eBooks
  70. How to Clear HBV cccDNA: CRISPR/Cas9 Might Be Promising
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  71. Genetic Engineering as a Driver for Biotechnological Developments and Cloning Tools to Improve Industrial Microorganisms
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  72. Improving Zinc Finger Nucleases - Strategies for Increasing Gene Editing Activities and Evaluating Off-Target Effects
    Cherie L. Ramirez · 2012 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
  73. Recombinant Pegylated first and third generation adenovirus vectors for delivery of anti-Hepatitis B virus RNA interference effectors
    Carol E. Crowther · 2014 · University of the Witwatersrand, Johannesburg Institutional Repository on DSpace (University of the Witwatersrand, Johannesburg)
  74. Gene Correction Technology and Its Impact on Viral Research and Therapy
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  75. Progress of genome editing approaches towards gene therapy
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  76. Recent advances in hepatitis B research and drug development
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  77. Genetic characterizations and epigenetic interference to better understand and fight occult Hepatitis B virus infection
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  78. Application of CRISPR/Cas9 in Treating Hepatitis B Virus
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  79. Immune Tolerance and Hepatitis B
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  80. Host factors involved in HBV cccDNA formation and transcription
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  81. Synthetic mRNA Gene Therapies and Hepatotropic Non-viral Vectors for the Treatment of Chronic HBV Infections
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