Streptococcus thermophilus CRISPR-cas9 systems enable specific editing of the human genome

Müller, Maximilian, Lee, Ciaran M, Gasiunas, Giedrius, Davis, Timothy H, Cradick, Thomas J, Siksnys, Virginijus, Bao, Gang, Cathomen, Toni +1 more·2016·Molecular Therapy

Cited by (254)

Items 201–254 of 254

  1. Rewriting the script: gene therapy and genome editing for von Willebrand Disease
    Alastair Barraclough, Isabel Bär, Tirsa T van Duijl, Karin Fijnvandraat, Jeroen C.J. Eikenboom, Frank W.G. Leebeek, Ruben Bierings, Jan Voorberg, Despoina Trasanidou · 2025 · Frontiers in Genome Editing
  2. Tapping into the Unsung Potential of CRISPR/CAS Technology in Agriculture
    Rao Saad Rehman, Mujahid Ali, Syed Ali Zafar, Muhammad Ahmad, Asad Nadeem Pasha, Hassan Bashir, Faiza Rashid, Mubashar Hussain · 2022 · Asian Journal of Biochemistry Genetics and Molecular Biology
  3. Versatile and robust genome editing with Streptococcus thermophilus CRISPR1-Cas9
    Daniel Agudelo, Sophie Carter, Minja Velimirovic, Alexis Duringer, Sébastien Levesque, Jean-François Rivest, Jérémy Loehr, Mathilde Mouchiroud, Denis Cyr, Paula J. Waters et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  4. Massively parallel quantification of CRISPR editing in cells by TRAP-seq enables better design of Cas9, ABE, CBE gRNAs of high efficiency and accuracy
    Xi Xiang, Kunli Qu, Xue Liang, Xiaoguang Pan, Jun Wang, Peng Han, Zhanying Dong, Lijun Liu, Jiayan Zhong, Tao Ma et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  5. How CRISPR Is Revolutionizing the Generation of New Models for Cancer Research
    Francisco J. Sánchez Rivera, Lukas E. Dow · 2023 · Cold Spring Harbor Perspectives in Medicine
  6. CRISPR/Cas-mediated genome editing: playing a versatile role in mitigating the challenges of sustainable rice improvement
    Byomkesh Dash, Sudhansu Sekhar Bhuyan, Raj Kishore Sahoo, Nibedita Swain, Kishor Jeughale, Suman Sarkar, Ramlakhan Verma, Chidambaranathan Parameswaran, B. N. Devanna, Sanghamitra Samantaray · 2025 · 3 Biotech
  7. Protein Engineering of DNA-Dependent Enzymes
    Anna V. Yudkina, Dmitry O. Zharkov · 2020 · Advances in experimental medicine and biology
  8. CRISPR-Cas orthologs and variants
    Margaret E. Scollan · 2021 · Elsevier eBooks
  9. Off-Target Effects of Crop Genome Editing and Its Minimization
    Ali Movahedi, Bahram Barati, Shuang Wang, Hui Wei, Honghua Ruan, Qiang Zhuge · 2022 · Springer eBooks
  10. CRISPR/Cas Mediated Genome Editing for Improving Stress Resilience in Plants
    Deepu Pandita · 2023 · Environmental science and engineering
  11. CRISPR/Cas9 Vector Construction for Gene Knockout
    Markus Freudhofmaier, Jacob W. Hoyle, Fatemeh Maghuly · 2024 · Methods in molecular biology
  12. Engineering of Cas9 for improved functionality
    Dhvani Sandip Vora, Jaspreet Kaur Dhanjal, Durai Sundar · 2020 · Elsevier eBooks
  13. Using of bioinformatic software methods for determining PAM sequences by analyzing of CRISPR sites
    Elena Maslovskaya, Д. В. Сосин, Aleksey A. Frolov, Ivan Pavlenko, Vladislav Zhadaev, Mihail Lebedev, Yaroslav Leonov, Nikita Ivashchenko, Viktoriya Sapozhnikova, Yulia Shaltaeva · 2020 · Procedia Computer Science
  14. The Use of CRISPR Technologies for Crop Improvement in Maize
    Joshua K. Young, Pierluigi Barone, Stephen L. Gasior, Spencer Jones, Vesna Djukanovic, Marissa K. Simon · 2022 · Springer eBooks
  15. Reengineering of the CRISPR/Cas System
    Zulqurnain Khan, Tahmina Sattar, Maria Siddique, Zulfiqar Ali, Asif Ali Khan, Syed Ovais Aftab, Muhammad Zubair Ghouri, Qaisar Sultan, Nauman Gulzar, Farooq Ahmad · 2022 · Springer eBooks
  16. Machine-Learning-Inferred and Energy-Landscape-Guided Analyses Reveal Kinetic Determinants of CRISPR/Cas9 Gene Editing
    Lei Jin, Risi Liyanage, Dongsheng Duan, Shi‐Jie Chen · 2026 · PRX Life
  17. How Genomic and Structural Context Could Shape JAK-STAT Variant Pathogenicity
    Markus Hoffmann, Hye‐Kyung Lee · 2026 · Twin Research and Human Genetics
  18. The future of pediatric gene therapy: CRISPR-Cas9, AI, and personalized medicine
    Yinping Pan, Jian Ding, W Wang, Dexin Xu, Jihuan Fan, Wenbin Zhang · 2026 · Pediatric Research
  19. IMPROVING THE FUNCTION OF CRISPR-CAS9 FOR GENOME EDITING THERAPY: EDITING THE EDITOR
    Alva Sahiri Alexander Supit · 2017 · Jurnal Bioteknologi & Biosains Indonesia (JBBI)
  20. Emerging strategies to minimize the off-target effects in CRISPR/Cas9 system
    Chengpei Ouyang · 2024 · International Conference on Biological Engineering and Medical Science (ICBioMed)
  21. Using CRISPR-Cas9 Genome Editing to Enhance Cell Based Therapies for the Treatment of Diabetes Mellitus
    Nicole A. J. Krentz, Francis C. Lynn · 2016 · Springer eBooks
  22. Engineering of Human-Induced Pluripotent Stem Cells for Precise Disease Modeling
    Paweł Lisowski · 2018 · Springer eBooks
  23. Green Fluorescent Protein Tagged Polycistronic Reporter System Reveals Functional Editing Characteristics of CRISPR-Cas
    Fayu Yang, Hao Zhang, Shuo Cai, Kiran Imtiaz, Mingchun Li, Mi Wang, Yingchun Liu, Feiqun Xue, Lifang Zhang, Feng Gu · 2022 · The CRISPR Journal
  24. Expanding the Scope of Base Editing in Crops Using Cas9 Variants
    Rukmini Mishra, Muntazir Mushtaq, Raj Kumar Joshi · 2022 · Springer eBooks
  25. Specificity of CRISPR‐Cas9 Gene Editing
    Niklas Selfjord, Alexandra Madsen, Pınar Akçakaya · 2022 · Wiley eBooks
  26. DeepEmbCas9: Cas9 coevolution and sgRNA structural information for CRISPR-Cas9 cleavage activity prediction
    Jeffrey Kelvin Mak, Péter Mináry · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  27. Genomeditierung in der Zell- und Gentherapie
    Jan Pruszak, Maximilian Müller, Saskia König, Toni Cathomen · 2017 · Transfusionsmedizin
  28. Uspostava rekombinantnih mišjih embrionalnih matičnih stanica u svrhu istraživanja fleksibilnosti DNA
    Ivan Mikičić · 2018
  29. Genome Editing Technologies: From Bench Side to Bedside
    Fulya Yaylacıoğlu Tuncay, Pervin Dinçer · 2018 · Acta Medica
  30. Genetic modification in CPVT patient specific induced pluripotent stem cells with CRISPR/Cas9
    Maximilian Zimmermann · 2019
  31. Interrogating genome function using CRISPR tools: a narrative review
    Xingjie Ren, Maya Asami Takagi, Yin Shen · 2020 · Journal of Bio-X Research
  32. Genome editing and RNA interference technologies in plants
    Tej Man Tamang, Tayebeh Kakeshpour, Ying Hu, Zhao Peng, Qingyu Wu · 2021 · Elsevier eBooks
  33. Genetic engineering in plants using CRISPRs
    Andriy Bilichak · 2021 · Elsevier eBooks
  34. Faculty Opinions recommendation of Therapeutic strategies for duchenne muscular dystrophy: an update.
    Maida B. Taylor · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  35. Mechanisms to investigate the nervous system : genetic engineering with adeno-associated viruses
    Tess Torregrosa · 2020
  36. CRISPR Cas
    Saša Šviković · 2022 · Wiley eBooks
  37. Genome Editing Is Revolutionizing Crop Improvement
    Rukmini Mishra, Raj Kumar Joshi, Kaijun Zhao · 2022 · Springer eBooks
  38. Molecular Mechanisms of Type II CRISPR ‐ Cas Systems
    Tautvydas Karvelis, Virginijus Šikšnys · 2022 · Wiley eBooks
  39. CRISPR/Cas9, a decade of genome editing tools to fix the DNA
    L. Santos · 2022 · Science Reviews Biology
  40. Plant Genome Editing
    Naoki Wada, Yuriko Osakabe, Keishi Osakabe · 2022 · CABI eBooks
  41. Role of stem cell engineering and or gene-editing technologies in eye diseases degeneration, and therapy
    Marwa Daghsni · 2023 · Elsevier eBooks
  42. The engineered single guide RNA structure as a biomarker for gene-editing reagent exposure
    Emmarie C. Ryan, Leslie M. Huggins, Joshua D. Podlevsky · 2023 · Scientific Reports
  43. Additional file 2 of Expanding the CRISPR/Cas genome-editing scope in Xenopus tropicalis
    Zhaoying Shi, Hao Jiang, Guang‐Hui Liu, Songyuan Shi, Xuan Zhang, Yonglong Chen · 2022 · Figshare
  44. Gene Editing in ErbB/HER Family-Mediated Cancer Immunology
    Ling Yin · 2025 · Genetics.
  45. Development of new increased fidelity SpCas9 variants
    Péter István Kulcsár · 2019
  46. Directed mutagenesis vis-à-vis crispr/cas in improving medicinal plants: a review and bibliometric analysis
    Poulomi Sen, Rounaq Ansari, Avishek Chatterjee, Bipradeep Mondal, Sudip Sengupta, Subhadwip Ghorai, Suvojit Bose, Soham Hazra · 2025 · Journal of Crop Science and Biotechnology
  47. Additional file 1 of Expanding the CRISPR/Cas genome-editing scope in Xenopus tropicalis
    Zhaoying Shi, Jiang, Hao, Guanghui Liu, Songyuan Shi, Zhang, Xuan, Yonglong Chen · 2022 · Figshare
  48. Single‐molecule DNA flow‐stretch assays for high‐throughput DNA –protein interaction studies
    Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, P. Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus · 2026 · FEBS Open Bio
  49. Engineering the genome of minimal bacteria using CRISPR/Cas9 tools
    Ιason Τsarmpopoulos · 2017
  50. Inhibition du récepteur d’aryl hydrocarbone pour optimiser les thérapies anticancéreuses à base de lymphocytes T
    Valentine De Castro · 2024 · theses.fr (ABES)
  51. CRISPR Epigenome Editing of IL1R1 Expression of Neurons that Innervate the Temporomandibular Joint or Knee Causes Reduced Sensitization to Osteoarthritic Environment
    Joshua D. Stover, Robby D. Bowles, Yenisel Cruz‐Almeida, Robert M. Caudle, Kyle D. Allen, Armen N. Akopian, Benjamin Russell Arenkiel, Başak Dönertaş Ayaz, Yangjin Bae, Bruna Balbino de Paula et al. · 2026 · Annals of Biomedical Engineering
  52. CRISPR Interference to Inhibit Oncogenes for Cancer Therapy
    Bin Guo · 2026 · International Journal of Molecular Sciences
  53. Practical design of gRNA: AI combined with CRISPR
    Paulo A. Zaini · 2026 · Elsevier eBooks
  54. CRISPR/Cas9 in soybean research: a measured leap toward genetic refinement
    Smrutirekha Sahu, Pandian Rajendran, Sanket Arunrao Ghumde, Diksha Prakash, Shikha Dixit, Deepak Pawar, Dharavath Nagaraju, Vinutha T, Sandeep B. Adavi, Palaiyur Nanjappan Sivalingam et al. · 2026 · Frontiers in Genome Editing