Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors

He, Weihai, Miao, Frederick J.-P., Lin, Daniel C.-H., Schwandner, Ralf T., Wang, Zhulun, Gao, Jinhai, Chen, Jin-Long, Tian, Hui +1 more·2004·Nature

DOI 10.1038/nature02488

Cited by (909)

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Emer E. Hackett, Frederick J. Sheedy · 2020 · Frontiers in Cellular and Infection Microbiology
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