A regulated auxin minimum is required for seed dispersal in Arabidopsis
Open accessAbstract
Local hormone maxima are essential for the development of multicellular structures and organs. For example, steroid hormones accumulate in specific cell types of the animal fetus to induce sexual differentiation and concentration peaks of the plant hormone auxin direct organ initiation and mediate tissue patterning. Here we provide an example of a regulated local hormone minimum required during organogenesis. Our results demonstrate that formation of a local auxin minimum is necessary for specification of the valve margin separation layer where Arabidopsis fruit opening takes place. Consequently, ectopic production of auxin, specifically in valve margin cells, leads to a complete loss of proper cell fate determination. The valve margin identity factor INDEHISCENT (IND) is responsible for forming the auxin minimum by coordinating auxin efflux in separation-layer cells. We propose that the simplicity of formation and maintenance make local hormone minima particularly well suited to specify a small number of cells such as the stripes at the valve margins.
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A regulated auxin minimum is required to establish the valve margin, a boundary zone essential for Arabidopsis fruit opening.
“In contrast, Sorefan et al. (2009) showed that a regulated auxin minimum is required to establish the valve margin, a boundary zone that is essential for Arabidopsis fruit opening.”
From <i>Divide et impera</i>: boundaries shape the plant body and initiate new meristems (2016) · cites this paper as Sorefan et al., 2009
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Research works printed but not linked: 4
- Roeder, A. H. K. & Yanofsky, M. F. in The Arabidopsis Book (eds Somerville, C. R. & Meyerowitz, E. M.) doi:10.1199/tab.0075 (Am. Soc. Plant Biol., 2006). · DOI
- Wisniewska, J. et al. PIN localization directs auxin flow in plants. Science 312, 883 (2006).
- Cutler, S. R., Ehrhardt, D. W., Griffitts, J. S. & Somerville, C. R. Random GFP:cDNA fusions enable visualization of subcellular structures in cells of Arabidopsis at a high frequency. Proc. Natl Acad. Sci. USA 97, 3718-3723 (2000).
- Han, S. & Kim, D. AtRTPrimer: database for Arabidopsis genome-wide homogeneous and specific RT-PCR primer-pairs. BMC Bioinformatics 7, 179 (2006).
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Wang, Q., Kohlen, W., Rossmann, S., Vernoux, T., & Theres, K. (2014) · The Plant Cell · doi:10.1105/tpc.114.123059 · Cited by 172 · see citing works
“However, in the reproductive stage, axillary branches are initiated evenly (Stirnberg et al., 1999, 2002) or in a basipetal sequence (Hempel and Feldman, 1994) at close proximity to the SAM.”
BackgroundInfluential<i>Divide et impera</i>: boundaries shape the plant body and initiate new meristems
Wang, Q., Hasson, A., Rossmann, S., & Theres, K. (2016) · New Phytologist · doi:10.1111/nph.13641 · Cited by 106 · see citing works
- Authors
- Sorefan, K., Girin, T., Liljegren, S. J., Ljung, K., Robles, P., Galván-Ampudia, C. S., Offringa, R., Friml, J., Yanofsky, M. F., & Østergaard, L.
- Affiliations
- John Innes Centre (GB)
- University of North Carolina at Chapel Hill (US)
- Umeå Plant Science Centre (SE)
- Universitat de Miguel Hernández d'Elx (ES)
- Leiden University (NL)
- University of California San Diego (US)
- Corresponding author
- Østergaard, Lars
- Venue
- Nature
- Published
- 2009-05
- Volume
- 459
- Issue
- 7246
- Pages
- 583-586
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W1968706891
- Cited by
- 289
- References
- 0
- Citations by year
- 2026: 5 · 2025: 18 · 2024: 14 · 2023: 9 · 2022: 8 · 2021: 11 · 2020: 12 · 2019: 17 · 2018: 15 · 2017: 15 · 2016: 14 · 2015: 25 · 2014: 27 · 2013: 26 · 2012: 26
- FWCI
- 29.55
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion, cc-by-nc)
- HAL (submittedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Ghent University Academic Bibliography (Ghent University) (submittedVersion)
- Funders
- National Science Foundation
- Fonds Wetenschappelijk Onderzoek
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek
- Directorate for Biological Sciences
- Biotechnology and Biological Sciences Research Council (BBS/E/J/00000613)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Molecular Biology Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Parasitism and Resistance
- Keywords
- seed dispersal, fruit dehiscence, auxin efflux carriers, separation layer, cell fate specification, Arabidopsis thaliana, transcription factors
- MeSH terms
- Biological Transport, Fruit, Indoleacetic Acids, Seeds, Protein Serine-Threonine Kinases, Arabidopsis, Gene Expression Regulation, Plant, Membrane Transport Proteins, Arabidopsis Proteins, Basic Helix-Loop-Helix Transcription Factors, Basic Helix-Loop-Helix Proteins
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