CCR3 is a target for age-related macular degeneration diagnosis and therapy
Takeda, Atsunobu, Baffi, Judit Z., Kleinman, Mark E., Cho, Won Gil, Nozaki, Miho, Yamada, Kiyoshi, Kaneko, Hiroki, Albuquerque, Romulo J. C., Dridi, Sami, Saito, Kuniharu, Raisler, Brian J., Budd, Steven J., Geisen, Pete, Munitz, Ariel, Ambati, Balamurali K., Green, Martha G., Ishibashi, Tatsuro, Wright, John D., Humbles, Alison A., Gerard, Craig J., Ogura, Yuichiro, Pan, Yuzhen, Smith, Justine R., Grisanti, Salvatore, Hartnett, M. Elizabeth, Rothenberg, Marc E., Ambati, Jayakrishna·2009·Nature
Cited by (260)
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- Reactive Oxygen Species in Plasma Medical Science (PAM and Cancer Therapy)2018 · Elsevier eBooks
- Surgical strategies for AMDBoris V. Stanzel, Frank Gerhard Holz · 2012 · Elsevier eBooks
- New light on allergy receptorMaria B. Grant · 2009 · Nature
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- Seeing the potential of targeting CCR3Katie Kingwell · 2009 · Nature Reviews Drug Discovery
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- The Role of The Oxidative Stress Product Carboxyethylpyrrole in Innate ImmunityAli M. Saeed · 2014
- Nanomaterials for Optical ImagingAnil V. Wagh, Ruchi Malik, Benedict Law · 2011 · Wiley eBooks
- What Is the Role of CCR3 in Choroidal Neovascularization?Yiwen Li, Deqiang Huang, Xin Xia, Zhengying Wang, Lingyu Luo, Rong Wen · 2011 · Advances in experimental medicine and biology
- Retinal neovascularization and its therapeutic agentsShinsuke Nakamura, Masamitsu Shimazawa, Hideaki Hara · 2010 · Folia Pharmacologica Japonica
- Age-related macular degeneration: the protective effects of omega-3 fatty acids as anti-inflammatory agentsJingsheng Tuo · 2010 · Expert Review of Ophthalmology
- A highly specific biomarker for early diagnosis and treatment of neovascular age-related macular degeneration.Khalil Ghasemi Falavarjani · 2010 · PubMed Central
- Research Highlight CCR3: Shedding New Light on a Dark Problem?A. Brett Mason, Josephine Hoh · 2014
- Studio di polimorfismi in geni coinvolti in patologie oculari angioproliferativeGenny Buson · 2011 · Padua Research Archive (University of Padova)
- Antiangiogenic Agents and Photodynamic TherapyAtul Kumar, Sumithra Mohanraj, Kavitha Duraipandi, Anuradha V. Pai · 2016 · Springer eBooks
- A Revised Hemodynamic Theory of Age-RelatedBradley D. Gelfand, Jayakrishna Ambati · 2016
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- Chemokine in der AugenheilkundeTim Bleul, Günther Schlunck, Thomas Reinhard, Thabo Lapp · 2017 · Der Ophthalmologe
- Eosinophils on trialJames Edward Pease, Timothy John Williams · 2018 · Clinical & Experimental Allergy
- Protein Microarrays: Valuable Tools for Ocular Diseases ResearchMaría Garranzo‐Asensio, Ana Montero‐Calle, Guillermo Solís‐Fernández, Rodrigo Barderas, Ana Guzmán‐Aránguez · 2019 · Current Medicinal Chemistry
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- [Javel's ophthalmometer, modified to corneal microscope].B VARGA · 1951 · PubMed
- Cyclops2009 · Canadian Journal of Ophthalmology
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- Treatments for age-related macular degeneration and novel options using CCR3 antagonistsJie Xu · 2024 · Highlights in Science Engineering and Technology
- Vascular endothelial-specific loss of TGF-beta signaling as a model for choroidal neovascularization and central nervous system vascular inflammationYanshu Wang, Amir Rattner, Zhongming Li, Philip M. Smallwood, Jeremy Nathans · 2025 · eLife
- Vascular endothelial-specific loss of TGF-beta signaling as a model for choroidal neovascularization and central nervous system vascular inflammationYanshu Wang, Amir Rattner, Zhongming Li, Philip M. Smallwood, Jeremy Nathans · 2025 · eLife
- Additional file 1 of Aqueous humor cytokine levels through microarray analysis and a sub-analysis based on optical coherence tomography in wet age-related macular degeneration patientsJoo, Jin-Ho, Hyejee Kim, Shin, Jae-Ho, Sang Woong Moon · 2021 · Figshare
- Additional file 7 of Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brainAimée Parker, Stefano Romano, Rebecca Ansorge, Aboelnour, Asmaa, Le Gall, Gwenaelle, George M. Savva, Matthew G. Pontifex, Andrea Telatin, Baker, David, Emily J. Jones et al. · 2022 · Figshare
- Additional file 5 of Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brainAimée Parker, Stefano Romano, Rebecca Ansorge, Aboelnour, Asmaa, Le Gall, Gwenaelle, George M. Savva, Matthew G. Pontifex, Andrea Telatin, Baker, David, Emily J. Jones et al. · 2022 · Figshare
- Additional file 3 of Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brainAimée Parker, Stefano Romano, Rebecca Ansorge, Aboelnour, Asmaa, Le Gall, Gwenaelle, George M. Savva, Matthew G. Pontifex, Andrea Telatin, Baker, David, Emily J. Jones et al. · 2022 · Figshare
- Additional file 6 of Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brainAimée Parker, Stefano Romano, Rebecca Ansorge, Aboelnour, Asmaa, Le Gall, Gwenaelle, George M. Savva, Matthew G. Pontifex, Andrea Telatin, Baker, David, Emily J. Jones et al. · 2022 · Figshare
- Additional file 2 of Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brainAimée Parker, Stefano Romano, Rebecca Ansorge, Aboelnour, Asmaa, Le Gall, Gwenaelle, George M. Savva, Matthew G. Pontifex, Andrea Telatin, Baker, David, Emily J. Jones et al. · 2022 · Figshare
- Additional file 4 of Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brainAimée Parker, Stefano Romano, Rebecca Ansorge, Aboelnour, Asmaa, Le Gall, Gwenaelle, George M. Savva, Matthew G. Pontifex, Andrea Telatin, Baker, David, Emily J. Jones et al. · 2022 · Figshare
- Evolving roles of drug delivery systems for non-invasive treatment of neovascular age-related macular degeneration: advances and challengesNunnarpas Yongvongsoontorn, Joo Eun Chung, Motoichi Kurisawa · 2026 · Journal of Drug Delivery Science and Technology
- Nouveaux mécanismes génétiques expliquant les vitréorétinopathies héréditaires et génération d’un modèle murin de la maladie de Wagner par approche CRISPR/Cas9Cyril Burin des Roziers · 2017
- People living with lower extremity peripheral artery disease demonstrate vascular regenerative cell deficiencies: The PAD-VRCE CardioLink-17 studyJohn H. Casey, Michael Moroney, Hwee Teoh, Aishwarya Krishnaraj, Adrian Quan, Yi Pan, Fallon Dennis, Arianna Z He, Brady Park, Raj Verma et al. · 2026 · JVS Vascular Science
- Quantum Dots in Ocular Surface: A Systematic ReviewSidra Sarwat, Mark D. P. Willcox, Fiona Jane Stapleton, Maitreyee Roy · 2026 · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology
- Leukocytes and age-related macular degenerationNicolai Sandau, Bryan R. Gorman, Jiao Luo, NS Peachey, Børge Grønne Nordestgaard, Anne Tybjærg‐Hansen, Jesper Qvist Thomassen, Sudha K. Iyengar, Ruth Frikke‐Schmidt · 2026 · European Journal of Epidemiology
- Disorders and diseases of the nervous systemAhmed El-hashash, Asha Rao, Manal El-Sawaf, Hirendra Banerjee · 2026 · Elsevier eBooks
- BindingDB Entry 50040685: Chemokine receptor antagonists.BindingDB · 2013 · UC San Diego