Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells

Pastor, William A., Pape, Utz J., Huang, Yun, Henderson, Hope R., Lister, Ryan, Ko, Myunggon, McLoughlin, Erin M., Brudno, Yevgeny, Mahapatra, Sahasransu, Kapranov, Philipp, Tahiliani, Mamta, Daley, George Q., Liu, X. Shirley, Ecker, Joseph R., Milos, Patrice M., Agarwal, Suneet, Rao, Anjana·2011·Nature

DOI 10.1038/nature10102

Cited by (814)

Items 401–500 of 814

Electrochemical biosensor for detection of DNA hydroxymethylation based on glycosylation and alkaline phosphatase catalytic signal amplification
Yunlei Zhou, Zhiqing Yang, Xue Li, Yue Wang, Huanshun Yin, Shiyun Ai · 2015 · Electrochimica Acta
The Involvement of 5-Hydroxymethylcytosine in Active DNA Demethylation in Mice1
Peng Zhang, Li Su, Zhongwei Wang, Sheng Zhang, Jiyu Guan, Yue Chen, Yupeng Yin, Fei Gao, Bo Tang, Ziyi Li · 2012 · Biology of Reproduction
A highly efficient fluorescence-based switch-on detection method of 5-formyluracil in DNA
Chaoxing Liu, Yuqi Chen, Yafen Wang, Fan Wu, Xiong Zhang, Wei Yang, Jiaqi Wang, Yi Chen, Zhiyong He, Guangrong Zou et al. · 2017 · Nano Research
Stem Cell Plasticity in Development and Cancer: Epigenetic Origin of Cancer Stem Cells
Mansi Shah, Cinzia Allegrucci · 2012 · Sub-cellular biochemistry/Subcellular biochemistry
Hydroxylation mediates chromatin demethylation
Y.-i. Tsukada · 2012 · The Journal of Biochemistry
Constitutional trisomy 8 mosaicism as a model for epigenetic studies of aneuploidy
Josef Davidsson, Srinivas Veerla, Bertil Johansson · 2013 · Epigenetics & Chromatin
5-Methylcytosine and Its Derivatives
Bi‐Feng Yuan · 2014 · Advances in clinical chemistry
oxBS-MLE: an efficient method to estimate 5-methylcytosine and 5-hydroxymethylcytosine in paired bisulfite and oxidative bisulfite treated DNA
Zongli Xu, Jack A. Taylor, Yuet‐Kin Leung, Shuk‐Mei Ho, Liang Niu · 2016 · Bioinformatics
Accurate quantification of 5-Methylcytosine, 5-Hydroxymethylcytosine, 5-Formylcytosine, and 5-Carboxylcytosine in genomic DNA from breast cancer by chemical derivatization coupled with ultra performance liquid chromatography- electrospray quadrupole time of flight mass spectrometry analysis
Mengzhe Guo, Xiao Li, Liyan Zhang, Dantong Liu, Wencheng Du, Dengyang Yin, Nan Lyu, Guangyu Zhao, Cheng Guo, Daoquan Tang · 2017 · Oncotarget
Tet2 Regulates Osteoclast Differentiation by Interacting with Runx1 and Maintaining Genomic 5-Hydroxymethylcytosine (5hmC)
Yajing Chu, Zhigang Zhao, David Sant, Ganqian Zhu, Sarah Merin Greenblatt, Lin Liu, Jinhuan Wang, Zeng Cao, Jeanette Cheng Tho, Chen Shi et al. · 2018 · Genomics Proteomics & Bioinformatics
Environmental exposures, stem cells, and cancer
Tasha Thong, Chanese A. Forté, Evan M. Hill, Justin A. Colacino · 2019 · Pharmacology & Therapeutics
Electrochemical biosensor for hydroxymethylated DNA detection and β-glucosyltransferase activity assay based on enzymatic catalysis triggering signal amplification
Huanshun Yin, Zhiqing Yang, Haiyan Wang, Yunlei Zhou, Shiyun Ai · 2016 · Sensors and Actuators B Chemical
Profiling of oxBS-450K 5-hydroxymethylcytosine in human placenta and brain reveals enrichment at imprinted loci
José Ramón Hernández Mora, Marta Sánchez-Delgado, Paolo Petazzi, Sebastián Morán, Manel Esteller, Isabel Iglesias‐Platas, David Monk · 2017 · Epigenetics
Advances in measuring DNA methylation
Ruixia Sun, Ping Zhu · 2021 · Blood Science
Whole-Genome Sequencing of 5-Hydroxymethylcytosine at Base Resolution by Bisulfite-Free Single-Step Deamination with Engineered Cytosine Deaminase
Neng‐Bin Xie, Min Wang, Wei Chen, Tong‐Tong Ji, Xia Guo, Fang‐Yin Gang, Ya-Feng Wang, Yu‐Qi Feng, Liang Yuan, Weimin Ci et al. · 2023 · ACS Central Science
Boronic acid-mediated polymerase chain reaction for gene- and fragment-specific detection of 5-hydroxymethylcytosine
Chao Zhao, Hailin Wang, Bailin Zhao, Cuiping Li, Ruichuan Yin, Maoyong Song, Baodong Liu, Zhen Liu, Guibin Jiang · 2014 · Nucleic Acids Research
A Knockin Reporter Allows Purification and Characterization of mDA Neurons from Heterogeneous Populations
Ninuo Xia, Fang Fang, Pengbo Zhang, Jun Cui, Chhavy Tep-Cullison, Tim Hamerley, Hyun Joo Lee, Theo D. Palmer, Brian B. Bothner, Jin Hyung Lee et al. · 2017 · Cell Reports
5-Hydroxymethylcytosine: Far Beyond the Intermediate of DNA Demethylation
Kaixi Zheng, Zhengbing Lyu, Jianqing Chen, Guodong Chen · 2024 · International Journal of Molecular Sciences
Epigenetics of human asthma and allergy: promises to keep.
Avery DeVries, Donata Vercelli · 2013 · PubMed
Hypersensitive quantification of global 5-hydroxymethylcytosine by chemoenzymatic tagging
Tamar Shahal, Omri Koren, Gabi Shefer, Naftali Stern, Yuval Ebenstein · 2018 · Analytica Chimica Acta
Bisulfite-free and single-nucleotide resolution sequencing of DNA epigenetic modification of 5-hydroxymethylcytosine using engineered deaminase
Neng‐Bin Xie, Min Wang, Tong‐Tong Ji, Xia Guo, Jiang-Hui Ding, Bi‐Feng Yuan, Yu‐Qi Feng · 2022 · Chemical Science
Loss of 5-hydroxymethylcytosine induces chemotherapy resistance in hepatocellular carcinoma via the 5-hmC/PCAF/AKT axis
Xiao-Jun Guo, Xiaoyong Huang, Xuan Yang, Jia‐Cheng Lu, Chuanyuan Wei, Chao Gao, Yan-Zi Pei, Yi Chen, Qi‐Man Sun, Jiabin Cai et al. · 2023 · Cell Death and Disease
Epigenetic modifications in mouse cerebellar Purkinje cells: effects of aging, caloric restriction, and overexpression of superoxide dismutase 1 on 5-methylcytosine and 5-hydroxymethylcytosine
Roy Lardenoije, Daniël van den Hove, Thomas S.J. Vaessen, Artemis Iatrou, Koen P.V. Meuwissen, Britt T.J. van Hagen, Günter Kenis, Harry W.M. Steinbusch, Christoph Schmitz, Bart P. F. Rutten · 2015 · Neurobiology of Aging
Epigenetic modifier alpha-ketoglutarate modulates aberrant gene body methylation and hydroxymethylation marks in diabetic heart
Rohini Dhat, Dattatray Mongad, Sivarupa Raji, Silpa Arkat, Nitish R. Mahapatra, Nishant Singhal, Sandhya L. Sitasawad · 2023 · Epigenetics & Chromatin
Enzymatic DNA oxidation: mechanisms and biological significance
Guoliang Xu, Colum P. Walsh · 2014 · BMB Reports
A validated quantitative liquid chromatography–tandem quadrupole mass spectrometry method for monitoring isotopologues to evaluate global modified cytosine ratios in genomic DNA
Makoto Tsuji, Hironori Matsunaga, Daisuke Jinno, Hiroki Tsukamoto, Naoto Suzuki, Yoshihisa Tomioka · 2014 · Journal of Chromatography B
The expanding scope and impact of epigenetic cytosine modifications
Monica Yun Liu, Jamie E. DeNizio, Emily K. Schutsky, Rahul M. Kohli · 2016 · Current Opinion in Chemical Biology
Erasure of Tet-Oxidized 5-Methylcytosine by a SRAP Nuclease
Soo-Mi Kweon, Bing Zhu, Yibu Chen, L. Aravind, Shuang-yong Xu, Douglas E. Feldman · 2017 · Cell Reports
DNA demethylation is a driver for chick retina regeneration
Agustín Luz-Madrigal, Erika Grajales‐Esquivel, Jared A. Tangeman, Sarah Kosse, Lin Liu, Kai Wang, Andrew Fausey, Chun Liang, Panagiotis A. Tsonis, Katia Del Rio‐Tsonis · 2020 · Epigenetics
TET1 and 5-Hydroxymethylation Preserve the Stem Cell State of Mouse Trophoblast
Claire E. Senner, Stephanie Chrysanthou, Sarah Burge, Haiyan Lin, Miguel Ramos Branco, Myriam Hemberger · 2020 · Stem Cell Reports
TET1 upregulation drives cancer cell growth through aberrant enhancer hydroxymethylation of HMGA2 in hepatocellular carcinoma
Kiyokazu Shirai, Genta Nagae, M. Seki, Yotaro Kudo, Asuka Kamio, Akimasa Hayashi, Atsushi Okabe, Satoshi Ota, Shuichi Tsutsumi, Takanori Fujita et al. · 2021 · Cancer Science
Epigenetic Modification of PD-1/PD-L1-Mediated Cancer Immunotherapy against Melanoma
Hikaru Nanamori, Yu Sawada · 2022 · International Journal of Molecular Sciences
Altered hydroxymethylome in the substantia nigra of Parkinson’s disease
Shishi Min, Qian Xu, Lixia Qin, Yujing Li, Ziyi Li, Chao Chen, Hao Wu, Junhai Han, Xiongwei Zhu, Peng Jin et al. · 2022 · Human Molecular Genetics
Higher 5-hydroxymethylcytosine identifies immortal DNA strand chromosomes in asymmetrically self-renewing distributed stem cells
Yang Hoon Huh, Justin Delgado Cohen, James L. Sherley · 2013 · Proceedings of the National Academy of Sciences
Genome-wide antagonism between 5-hydroxymethylcytosine and DNA methylation in the adult mouse brain
Junjie U. Guo, Keith E. Szulwach, Yijing Su, Yujing Li, Bing Yao, Zihui Xu, Joo Heon Shin, Bing Xie, Yuan Gao, Guo‐li Ming et al. · 2014 · Frontiers in Biology
5-Hydroxymethylcytosine in E-box motifs ACAT|GTG and ACAC|GTG increases DNA-binding of the B-HLH transcription factor TCF4
Syed Khund-Sayeed, Ximiao He, Timothy R Holzberg, Jun Wang, Divya Rajagopal, Shriyash Upadhyay, Stewart R. Durell, Sanjit Mukherjee, Matthew T. Weirauch, Robert B. Rose et al. · 2016 · Integrative Biology
Current and Emerging Technologies for the Analysis of the Genome-Wide and Locus-Specific DNA Methylation Patterns
Jörg Tost · 2016 · Advances in experimental medicine and biology
H2A.B facilitates transcription elongation at methylated CpG loci
Yibin Chen, Qiang Chen, Richard C. McEachin, James D. Cavalcoli, Xiaochun Yu · 2014 · Genome Research
A dynamic multi-compartmental model of DNA methylation with demonstrable predictive value in hematological malignancies
Andrew Peter McGovern, Benjamin E. Powell, Timothy J. T. Chevassut · 2012 · Journal of Theoretical Biology
DNA hypermethylation of alternatively spliced and repeat sequences in humans
Andigoni Malousi, Sofia Kouidou · 2012 · Molecular Genetics and Genomics
TET family regulates the embryonic pluripotency of porcine preimplantation embryos by maintaining the DNA methylation level of NANOG
Kyungjun Uh, Junghyun Ryu, Kayla Farrell, Noah Wax, Kiho Lee · 2020 · Epigenetics
Tight correlation of 5-hydroxymethylcytosine and Polycomb marks in health and disease
Michael C. Haffner, Laxmi Gurunatham Pellakuru, Susmita Ghosh, Tamara Levin Lotan, William G. Nelson, Angelo De Marzo, Srinivasan Yegnasubramanian · 2013 · Cell Cycle
Fast and precise detection of DNA methylation with tetramethylammonium-filled nanopore
Ying Wang, Yani Zhang, Yanli Guo, Xiaofeng Kang · 2017 · Scientific Reports
OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide
Hugo Sepúlveda, Xiang Li, Leo J. Arteaga-Vazquez, Isaac F. López-Moyado, Melina Brunelli, Lot Hernández-Espinosa, Xiaojing Yue, J. Carlos Angel, Caitlin Brown, Zhen Dong et al. · 2025 · Nature Structural & Molecular Biology
Cytosine modifications in the honey bee (Apis mellifera) worker genome
Erik M. K. Rasmussen, Gro Vang Amdam · 2015 · Frontiers in Genetics
Methylation-Demethylation Dynamics: Implications of Changes in Acute Kidney Injury
Anubhav Chakraborty, Pragasam Viswanathan · 2018 · Analytical Cellular Pathology
The Role of DNA Methylation and DNA Methyltransferases in Cancer
Daniel J. Weisenberger, Ranjani Lakshminarasimhan, Gangning Liang · 2022 · Advances in experimental medicine and biology
Epigenetics and chromatin dynamics: a review and a paradigm for functional disorders
T. Ordog, Sabriya A. Syed, Yujiro Hayashi, David T. Asuzu · 2012 · Neurogastroenterology & Motility
Epigenetic Regulation of Stem Cells
Anton Wutz · 2013 · Advances in experimental medicine and biology
Real-time dynamics of methyl-CpG-binding domain protein 3 and its role in DNA demethylation by fluorescence correlation spectroscopy
Yi Cui, Il-Hoon Cho, Basudev Chowdhury, Joseph Irudayaraj · 2013 · Epigenetics
Ten-eleven translocation 1 dysfunction reduces 5‑hydroxymethylcytosine expression levels in gastric cancer cells
Kuo‐Chiang Wang, Chi‐Hsiang Kang, Chung‐Yu Tsai, Nan–Hua Chou, Ya‑Ting Tu, Guancheng Li, Hing‐Chung Lam, Shiuh‐Inn Liu, Po‐Min Chang, Yan‐Hwai Lin et al. · 2017 · Oncology Letters
Mutant IDH : A Targetable Driver of Leukemic Phenotypes Linking Metabolism, Epigenetics and Transcriptional Regulation
Garrett-Bakelman, Francine E, Melnick, Ari M · 2016 · Epigenomics
The Association between Long-Term DDT or DDE Exposures and an Altered Sperm Epigenome—a Cross-Sectional Study of Greenlandic Inuit and South African VhaVenda Men
Ariane Lismer, Xiaojian Shao, Marie-Charlotte Dumargne, Christine Lafleur, Romain Lambrot, Donovan Chan, Gunnar Vase Toft, Jens Peter Bonde, Amanda J MacFarlane, Riana Bornman et al. · 2024 · Environmental Health Perspectives
The Epigenome in Pluripotency and Differentiation
Rathi D. Thiagarajan, Robert E. Morey, Louise Chang Laurent · 2014 · Epigenomics
Active DNA demethylation in mammalian preimplantation embryos: new insights and new perspectives
Junying Ma, Xuefang Liang, H. Schatten, Qing‐Yuan Sun · 2012 · Molecular Human Reproduction
Assessment of ‘one-step’ versus ‘sequential’ embryo culture conditions through embryonic genome methylation and hydroxymethylation changes
Juliette Salvaing, Nathalie Peynot, Mohammed Bedhane, S. Veniel, Emilie Pellier, Claire Boulesteix, Nathalie Beaujean, Nathalie Daniel, Véronique Duranthon · 2016 · Human Reproduction
Precise genomic mapping of 5-hydroxymethylcytosine via covalent tether-directed sequencing
Povilas Gibas, Milda Narmontė, Zdislav Staševskij, Juozas Gordevičius, Saulius Klimašauskas, Edita Kriukienė · 2020 · PLoS Biology
5-Hydroxymethylcytosine-Mediated DNA Demethylation in Stem Cells and Development
Wenjia Sun, Min‐Xin Guan, Xuekun Li · 2014 · Stem Cells and Development
A critical appraisal of tools available for monitoring epigenetic changes in clinical samples from patients with myeloid malignancies
Kirsten Grønbæk, Carsten Müller‐Tidow, Giovanni Perini, Sören Lehmann, Marianne Bach Treppendahl, Ken Mills, Christoph Plass, Brigitte Schlegelberger, on behalf of the European Genomics and Epigenomics Study on MDS and AML (EuGESMA), COST Action BM0801 · 2012 · Haematologica
Application of N-Halogeno-N-sodiobenzenesulfonamide Reagents to the Selective Detection of 5-Methylcytosine in DNA Sequences
Tianlu Wang, Tingting Hong, Tun Tang, Qianqian Zhai, Xiwen Xing, Wuxiang Mao, Xiaolong Zheng, Liang Xu, Jinjun Wu, Xiaocheng Weng et al. · 2013 · Journal of the American Chemical Society
5-Formylcytosine is an activating epigenetic mark for RNA Pol III during zygotic reprogramming
Eleftheria Parasyraki, Medhavi Mallick, Victoria Hatch, Viviana Vastolo, Michael U. Musheev, Emil Karaulanov, Alexander V. Gopanenko, Simon Moxon, María Méndez-Lago, Dandan Han et al. · 2024 · Cell
TWIST1 induces MMP3 expression through up-regulating DNA hydroxymethylation and promotes catabolic responses in human chondrocytes
Joe Hasei, Takeshi Teramura, Toshiyuki Takehara, Yuta Onodera, Takuro Horii, Merissa Olmer, Izuho Hatada, Kanji Fukuda, Toshifumi Ozaki, Martin Lotz et al. · 2017 · Scientific Reports
Engineered Split-TET2 Enzyme for Inducible Epigenetic Remodeling
Minjung Lee, Jia Li, Yi Liang, Guolin Ma, Jixiang Zhang, Lian He, Yuliang Liu, Qian Li, Minyong Li, Deqiang Sun et al. · 2017 · Journal of the American Chemical Society
DNA methylation plays important roles in retinal development and diseases
Jing Wu, Linlin Liu, Miao Cao, Ang Hu, Die Hu, Yan Luo, Hui Wang, Jianing Zhong · 2021 · Experimental Eye Research
DNA Hydroxymethylation in Smoking-Associated Cancers
Ahmad Besarati Nia, Amanda Caceres, Stella Tommasi · 2022 · International Journal of Molecular Sciences
Enhanced photoactivity of CdS nanorods by MXene and ZnSnO3: Application in photoelectrochemical biosensor for the effect of environmental pollutants on DNA hydroxymethylation in wheat tissues
Yulin Zheng, Yunlei Zhou, Xiaoting Cui, Huanshun Yin, Shiyun Ai · 2022 · Materials Today Chemistry
5‐hydroxymethylcytosine marks postmitotic neural cells in the adult and developing vertebrate central nervous system
Nicolas Diotel, Yohann Mérot, Pascal Coumailleau, M. Guéguen, Aurélien A. Sérandour, Gilles Salbert, Olivier Kah · 2016 · The Journal of Comparative Neurology
Control over single-cell distribution of G1 lengths by WNT governs pluripotency
Jiwon Jang, Dasol Han, Mahdi Golkaram, Morgane Audouard, Guojing Liu, Daniel C. Bridges, Stefan Hellander, Alex Chialastri, Siddharth S. Dey, Linda Ruth Petzold et al. · 2019 · PLoS Biology
5-Hydroxymethylcytosine modifications in circulating cell-free DNA: frontiers of cancer detection, monitoring, and prognostic evaluation
Danjun Song, Zhou Zhang, Jiaping Zheng, Weidong Zhang, Jiabin Cai · 2025 · Biomarker Research
Brain 5-hydroxymethylcytosine alterations are associated with Alzheimer’s disease neuropathology
Jinying Zhao, Tongjun Gu, Cheng Gao, Guanhong Miao, Helena Palma‐Gudiel, Lei Yu, Jingyun Yang, Yanling Wang, Yujing Li, Jung-Hwa Lim et al. · 2025 · Nature Communications
Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells
Xavier Tekpli, Alfonso Urbanucci, Adnan Hashim, Cathrine Broberg Vågbø, Robert Lyle, Marianne Kristiansen Kringen, Anne Cathrine Staff, Ingunn Dybedal, Ian Geoffrey Mills, Arne Klungland et al. · 2016 · Epigenetics & Chromatin
Interrogating Key Positions of Size-Reduced TALE Repeats Reveals a Programmable Sensor of 5-Carboxylcytosine
Sara Maurer, Mario Gieß, Oliver Koch, Daniel Summerer · 2016 · ACS Chemical Biology
A sensitive signal-off electrogenerated chemiluminescence biosensing method for the discrimination of DNA hydroxymethylation based on glycosylation modification and signal quenching from ferroceneboronic acid
Yuling Zhang, Yan Li, Yingying Wei, Huiping Sun, Huan Wang · 2017 · Talanta
Epigenetic Regulation of Circadian Clocks and Its Involvement in Drug Addiction
Lamis Saad, Jean Zwiller, Andries Kalsbeek, Patrick Anglard · 2021 · Genes
A genome-wide screen reveals new regulators of the 2-cell-like cell state
Nikhil Gupta, Lounis Yakhou, Julien Richard Albert, Anaelle Azogui, Laure Ferry, Olivier Kirsh, Fumihito Miura, Sarah Battault, Kosuke Yamaguchi, Marthe Laisné et al. · 2023 · Nature Structural & Molecular Biology
Methods for Cancer Epigenome Analysis
Raman P. Nagarajan, Shaun D. Fouse, Robert J.A. Bell, J Costello · 2012 · Advances in experimental medicine and biology
Promises and challenges of anticancer drugs that target the epigenome
Inge Verbrugge, Ricky W. Johnstone, Michael L Bots · 2011 · Epigenomics
Genome-wide expression of non-coding RNA and global chromatin modification
Rukui Zhang, Lan Zhang, Wenqiang Yu · 2011 · Acta Biochimica et Biophysica Sinica
Filtrating colorectal cancer associated genes by integrated analyses of global DNA methylation and hydroxymethylation in cancer and normal tissue
Ming Li, Fei Gao, Yudong Xia, Yi Tang, Wei Zhao, Congcong Jin, Huijuan Luo, Junwen Wang, Qingshu Li, Yalan Wang · 2016 · Scientific Reports
UHRF2 regulates local 5-methylcytosine and suppresses spontaneous seizures
Yidan Liu, Bin Zhang, Xiaoyu Meng, Matthew J. Korn, Jack M. Parent, Lin‐Yu Lu, Xiaochun Yu · 2017 · Epigenetics
Thioether Macrocyclic Peptides Selected against TET1 Compact Catalytic Domain Inhibit TET1 Catalytic Activity
Kosuke Nishio, Roman Belle, Takayuki Katoh, Akane Kawamura, Toru Sengoku, Kazuharu Hanada, Noboru Ohsawa, Mikako Shirouzu, Shigeyuki Yokoyama, Hiroaki Suga · 2018 · ChemBioChem
Effects of 5-Hydroxymethylcytosine Epigenetic Modification on the Stability and Molecular Recognition of VEGF i-Motif and G-Quadruplex Structures
Rhianna K. Morgan, Michael M. Molnar, Harshul Batra, Bethany Summerford, Randy M. Wadkins, Tracy Ann Brooks · 2018 · Journal of Nucleic Acids
Methods for Detection and Mapping of Methylated and Hydroxymethylated Cytosine in DNA
Кисиль Ольга Валерьевна, Alexander V. Sergeev, Anna V. Bacheva, Maria I. Zvereva · 2024 · Biomolecules
Biological and Biochemical Modulation of DNA Methylation
Raymond Lo, Rosanna Weksberg · 2014 · Epigenomics
Epigenetic mapping of the somatotropic axis in Nile tilapia reveals differential DNA hydroxymethylation marks associated with growth
Ioannis Konstantinidis, Dafni Anastasiadi, Pål Sætrom, Artem Nedoluzhko, Robin Mjelle, Tomasz Podgorniak, Francesc Piferrer, Jorge M. O. Fernandes · 2021 · Genomics
The promoter methylomes of monochorionic twin placentas reveal intrauterine growth restriction-specific variations in the methylation patterns
Zhiming He, Hanlin Lu, Huijuan Luo, Fei Gao, Tong Wang, Yu Gao, Qun Fang, Junwen Wang · 2016 · Scientific Reports
Investigating 5-Hydroxymethylcytosine (5hmC): The State of the Art
Colm E. Nestor, James P. Reddington, Mikael Benson, Richard R. Meehan · 2013 · Methods in molecular biology
Unraveling the genetic underpinnings of myeloproliferative neoplasms and understanding their effect on disease course and response to therapy: Proceedings from the 6th international post‐ASH symposium
Omar Ibrahim Abdel-Wahab, Animesh Dev Pardanani, Olivier Bernard, Guido Finazzi, John D. Crispino, Heinz Gisslinger, Róbert Královics, Olatoyosi M. Odenike, Kapil N. Bhalla, Vikas K Gupta et al. · 2012 · American Journal of Hematology
miR‐29c‐3p regulates TET2 expression and inhibits autophagy process in Parkinson's disease models
Ruili Wang, Jie Yao, Fuhua Gong, Songsheng Chen, Ya He, Chunting Hu, Chen Li · 2021 · Genes to Cells
Zinc Finger Protein 618 Regulates the Function of UHRF2 (Ubiquitin-like with PHD and Ring Finger Domains 2) as a Specific 5-Hydroxymethylcytosine Reader
Yidan Liu, Bin Zhang, Henry Kuang, Gautam Korakavi, Lin‐Yu Lu, Xiaochun Yu · 2016 · Journal of Biological Chemistry
Multiple Functions of Ten-eleven Translocation 1 during Tumorigenesis
Yiping Tian, Yimin Zhu, Xiaohui Sun, Maode Lai · 2016 · Chinese Medical Journal
Phosphorylation of Tet3 by cdk5 is critical for robust activation of BRN2 during neuronal differentiation
Vinay Kumar Rao, Swarnaseetha Adusumalli, Guo-Hong Tham, Wei‐Qi Lin, Binbin Han, Touati Benoukraf, Guoliang Xu, Chin‐Tong Ong · 2019 · Nucleic Acids Research
Evidence for novel epigenetic marks within plants
Asaad M. Mahmood, Jim M. Dunwell · 2019 · Global Medical Genetics
The role of TET-mediated DNA hydroxymethylation in prostate cancer
Elien Smeets, Andy G. Lynch, Stefan Preković, Thomas Van den Broeck, Lisa Moris, Christine Helsen, Steven Joniau, Frank Claessens, Charlie E. Massie · 2017 · Molecular and Cellular Endocrinology
DNA 5-Hydroxymethylation in Human Adipose Tissue Differs Between Subcutaneous and Visceral Adipose Tissue Depots
Kerstin Rohde, Maria Keller, Michael Stümvoll, Arne Dietrich, Matthias Blüher, Yvonne Böttcher · 2015 · Epigenomics
Epigenetics and Heart Failure
Syeda Shegufta Ameer, Mohammad Bakhtiar Hossain, Ralph Knöll · 2020 · International Journal of Molecular Sciences
Hydroxymethylation-Specific Ligation-Mediated Single Quantum Dot-Based Nanosensors for Sensitive Detection of 5-Hydroxymethylcytosine in Cancer Cells
Ziyue Wang, Huimin Yuan, Dongling Li, Juan Hu, Jian‐Ge Qiu, Chun‐yang Zhang · 2022 · Analytical Chemistry
TET3-mediated DNA oxidation is essential for intestinal epithelial cell response to stressors
Edward A. Gonzalez, Yue Liu, Dahui Wang, Maciej Jeziorek, Sheila Bandyopadhyay, Anjana Rao, Nan Gao, Jean‐Pierre Etchegaray · 2023 · Proceedings of the National Academy of Sciences
Active DNA demethylation of developmental cis -regulatory regions predates vertebrate origins
Ksenia Skvortsova, Stéphanie Bertrand, Danila Voronov, Paul E. Duckett, Samuel E. Ross, Marta Silvia Magri, Ignacio Maeso, Robert J. Weatheritt, José Luis Gómez-Skármeta, Maria Ina Arnone et al. · 2022 · Science Advances
Inducible disruption of Tet genes results in myeloid malignancy, readthrough transcription, and a heterochromatin-to-euchromatin switch
Hiroshi Yuita, Isaac F. López-Moyado, Hyeongmin Jeong, Arthur Xiuyuan Cheng, James P Scott-Browne, Jungeun An, Toshinori Nakayama, Atsushi Onodera, Myunggon Ko, Anjana Rao · 2023 · Proceedings of the National Academy of Sciences