Cited by 4,010Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

The DOI matches its Crossref record; 99 of the 100 references it cites were found in a registry or an index.

Progress and challenges in translating the biology of atherosclerosis

Abstract

Atherosclerosis is a chronic disease of the arterial wall, and a leading cause of death and loss of productive life years worldwide. Research into the disease has led to many compelling hypotheses about the pathophysiology of atherosclerotic lesion formation and of complications such as myocardial infarction and stroke. Yet, despite these advances, we still lack definitive evidence to show that processes such as lipoprotein oxidation, inflammation and immunity have a crucial involvement in human atherosclerosis. Experimental atherosclerosis in animals furnishes an important research tool, but extrapolation to humans requires care. Understanding how to combine experimental and clinical science will provide further insight into atherosclerosis and could lead to new clinical applications.

Overview

Integrity signals

Registry

Crossref · 10.1038/nature10146

Cites

99 of 99 references verified0 citation errors · 0 not checkable

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Verification

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Citations

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Metadata

Authors
Libby, P., Ridker, P. M., & Hansson, G. K.
Affiliations
  • Brigham and Women's Hospital (US)
  • Karolinska University Hospital (SE)
Corresponding author
Libby, Peter
Venue
Nature
Published
2011-05
Volume
473
Issue
7347
Pages
317-325
ISSN
  • 0028-0836 (ISSN-L)
  • 1476-4687
OpenAlex
W2033896075
Cited by
4,010
References
100
Citations by year
2026: 169 · 2025: 235 · 2024: 252 · 2023: 249 · 2022: 283 · 2021: 342 · 2020: 299 · 2019: 264 · 2018: 271 · 2017: 304 · 2016: 271 · 2015: 286 · 2014: 258 · 2013: 232 · 2012: 230
FWCI
22.29
Type
journal article
Language
en
Open access
closed
Locations
  • Nature (publishedVersion)
  • PubMed (publishedVersion)
  • RePEc: Research Papers in Economics (submittedVersion)
Topics
  • Life Sciences › Immunology and Microbiology › Immunology › Atherosclerosis and Cardiovascular Diseases
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Cholesterol and Lipid Metabolism
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
Keywords
atherosclerosis, atherosclerotic plaque formation, lipoprotein oxidation, inflammation, immunity, animal models, animal-to-human extrapolation, myocardial infarction, stroke, translational research
MeSH terms
Animals, Humans, Inflammation, Cholesterol, HDL, Cholesterol, LDL, Triglycerides, Atherosclerosis, Lipid Metabolism

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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

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