The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Nuclear export dynamics of RNA–protein complexes
Open accessAbstract
The central dogma of molecular biology — DNA makes RNA makes proteins — is a flow of information that in eukaryotes encounters a physical barrier: the nuclear envelope, which encapsulates, organizes and protects the genome. Nuclear-pore complexes, embedded in the nuclear envelope, regulate the passage of molecules to and from the nucleus, including the poorly understood process of the export of RNAs from the nucleus. Recent imaging approaches focusing on single molecules have provided unexpected insight into this crucial step in the information flow. This review addresses the latest studies of RNA export and presents some models for how this complex process may work.
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Cites
Macromolecular crowding: an important but neglected aspect of the intracellular environment
Ellis, R. J. (2001) · Current Opinion in Structural Biology · doi:10.1016/s0959-440x(00)00172-x · Cited by 1,153
A Conserved mRNA Export Machinery Coupled to pre-mRNA Splicing
Reed, R., & Hurt, E. (2002) · Cell · doi:10.1016/s0092-8674(02)00627-x · Cited by 400
Cited by
Regulation of mammalian cell differentiation by long non‐coding RNAs
Hu, W., Alvarez‐Dominguez, J. R., & Lodish, H. F. (2012) · EMBO reports · doi:10.1038/embor.2012.145 · Cited by 309
Long non-coding RNAs: modulators of nuclear structure and function
Bergmann, J. H., & Spector, D. L. (2014) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2013.08.005 · Cited by 256
Subcellular mRNA kinetic modeling reveals nuclear retention as rate-limiting
(2024) · doi:10.1038/s44320-024-00073-2 · Cited by 14
Metadata
- Authors
- Grünwald, D., Singer, R. H., & Rout, M.
- Venue
- Nature
- Published
- 2011-07
- Volume
- 475
- Issue
- 7356
- Pages
- 333-341
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W1963670734
- Cited by
- 190
- References
- 2
- FWCI
- 8.82
- Type
- journal article
- Language
- en
- Open access
- green
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