The DOI matches its Crossref record; 96 of the 96 references it cites were found in a registry or an index.
Pharmacogenomics in the clinic
Open accessAbstract
After decades of discovery, inherited variations have been identified in approximately 20 genes that affect about 80 medications and are actionable in the clinic. And some somatically acquired genetic variants direct the choice of 'targeted' anticancer drugs for individual patients. Current efforts that focus on the processes required to appropriately act on pharmacogenomic variability in the clinic are moving away from discovery and towards implementation of an evidenced-based strategy for improving the use of medications, thereby providing a cornerstone for precision medicine.
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Cites
ClinVar: public archive of relationships among sequence variation and human phenotype
Landrum, M. J., Lee, J. M., Riley, G. R., Jang, W., Rubinstein, W. S., Church, D. M., & Maglott, D. R. (2014) · Nucleic Acids Research · doi:10.1093/nar/gkt1113 · Cited by 3,516
HLA-B*5701 Screening for Hypersensitivity to Abacavir
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Pharmacogenomics Knowledge for Personalized Medicine
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Nelson, G., Bakkum-Gamez, J., Kalogera, E., Glaser, G., Altman, A., Meyer, L. A., Taylor, J. S., Iniesta, M., Lasala, J., Mena, G., et al. (2019) · International Journal of Gynecological Cancer · doi:10.1136/ijgc-2019-000356 · Cited by 758
Pharmacogenomics of GPCR Drug Targets
Hauser, A. S., Chavali, S., Masuho, I., Jahn, L. J., Martemyanov, K. A., Gloriam, D. E., & Babu, M. M. (2018) · Cell · doi:10.1016/j.cell.2017.11.033 · Cited by 616
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Abul-Husn, N. S., & Kenny, E. E. (2019) · Cell · doi:10.1016/j.cell.2019.02.039 · Cited by 355
Variant interpretation: functional assays to the rescue
Starita, L. M., Ahituv, N., Dunham, M. J., Kitzman, J. O., Roth, F. P., Seelig, G., Shendure, J., & Fowler, D. M. (2017) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2017.07.014 · Cited by 381
Metadata
- Authors
- Relling, M. V., & Evans, W. E.
- Venue
- Nature
- Published
- 2015-10
- Volume
- 526
- Issue
- 7573
- Pages
- 343-350
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W1896195310
- Cited by
- 904
- References
- 96
- FWCI
- 77.65
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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