Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 365

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Hox protein mutation and macroevolution of the insect body plan

Ronshaugen, Matthew, McGinnis, Nadine, McGinnis, William·2002·Nature
DOI 10.1038/nature716
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1038/nature716

Cites

1 of 1 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 1 references

Research works printed but not linked: 23

  1. Goldschmidt, R. The Material Basis of Evolution (Yale Univ. Press, New Haven, Connecticut, 1940)
  2. Lewis, E. B. A gene complex controlling segmentation in Drosophila. Nature 276, 565–570 (1978) · DOI
  3. Carroll, S. B., Grenier, J. K. & Weatherbee, S. D. From DNA to Diversity (Blackwell Science, London, 2001)
  4. Boore, J. L., Collins, T. M., Stanton, D., Daehler, L. L. & Brown, W. M. Deducing the pattern of arthropod phylogeny from mitochondrial DNA rearrangements. Nature 376, 163–165 (1995) · DOI · Paper page
  5. Friedrich, M. & Tautz, D. Ribosomal DNA phylogeny of the major extant arthropod classes and the evolution of myriapods. Nature 376, 165–167 (1995) · DOI · Paper page
  6. Regier, J. C. & Shultz, J. W. Molecular phylogeny of the major arthropod groups indicates polyphyly of crustaceans and a new hypothesis for the origin of hexapods. Mol. Biol. Evol. 14, 902–913 (1997) · DOI
  7. Averof, M. & Akam, M. Hox genes and the diversification of insect and crustacean body plans. Nature 376, 420–423 (1995) · DOI · Paper page
  8. Averof, M. & Patel, N. Crustacean appendage evolution associated with changes in Hox gene expression. Nature 388, 682–686 (1997) · DOI · Paper page
  9. Panganiban, G., Sebring, A., Nagy, L. & Carroll, S. The development of crustacean limbs and the evolution of arthropods. Science 270, 1363–1366 (1995) · DOI · Paper page
  10. Abzhanov, A. & Kaufman, T. C. Crustacean (malacostracan) Hox genes and the evolution of the arthropod trunk. Development 127, 2239–2249 (2000) · DOI
  11. Li, X. & McGinnis, W. Activity regulation of Hox proteins, a mechanism for altering functional specificity in development and evolution. Proc. Natl Acad. Sci. USA 96, 6802–6807 (1999) · DOI
  12. Gonzalez-Reyes, A. & Morata, G. The developmental effect of overexpressing a Ubx product in Drosophila embryos is dependent on its interactions with other homeotic products. Cell 61, 515–522 (1990) · DOI
  13. Mann, R. S. & Hogness, D. S. Functional dissection of Ultrabithorax protein in D. melanogaster. Cell 60, 597–610 (1990) · DOI · Paper page
  14. Grenier, J. K. & Carroll, S. B. Functional evolution of the Ultrabithorax protein. Proc. Natl Acad. Sci. USA 97, 704–709 (2000) · DOI
  15. Vachon, G. et al. Homeotic genes of the bithorax complex repress limb development in the abdomen of the Drosophila embryo through the target gene Distal-less. Cell 71, 437–450 (1992) · DOI · Paper page
  16. Chan, S. & Mann, R. S. The segment identity functions of Ultrabithorax are contained within its homeo domain and carboxy-terminal sequences. Genes Dev. 7, 796–811 (1993) · DOI
  17. Galant, R. & Carroll, S. B. Evolution of a transcriptional repression domain in an insect Hox protein. Nature advance online publication, 6 February 2002 (DOI 10.1038/nature717). · DOI · Paper page
  18. Fiol, C. J., Mahrenholz, A. M., Wang, Y., Boeske, R. W. & Roach, P. J. Formation of protein kinase recognition sites by covalent modification of the substrate. J. Biol. Chem. 262, 14042–14048 (1987) · DOI · Paper page
  19. Jaffe, L., Ryoo, H. & Mann, R. S. A role for phosphorylation by casein kinase II in modulating Antennapedia activity in Drosophila. Genes Dev. 11, 1327–1340 (1997) · DOI
  20. Fienberg, A. A. et al. Phylogenetically conserved CK-II phosphorylation site of the murine homeodomain protein Hoxb-6. J. Exp. Zool. 285, 76–84 (1999) · DOI
  21. Li, C. & Manley, J. L. Allosteric regulation of Even-skipped repression activity by phosphorylation. Mol. Cell 3, 77–86 (2000) · DOI
  22. Grenier, J. K., Garber, T. L., Warren, R., Whitington, P. M. & Carroll, S. Evolution of the entire arthropod Hox gene set predated the origin and radiation of the onychophoran/arthropod clade. Curr. Biol. 7, 547–553 (1997) · DOI
  23. Kelsh, R. R. O. J. W., White, R. A. H. & Akam, M. Homeotic gene expression in the locust Schistocerca: An antibody that detects conserved epitopes in ultrabithorax and abdominal-A proteins. Dev. Genet. 15, 19–31 (1994) · DOI

Cited by

See all 365

Metadata

Authors
Ronshaugen, M., McGinnis, N., & McGinnis, W.
Venue
Nature
Publisher
Springer Science and Business Media LLC
Published
2002-02
Volume
415
Issue
6874
Pages
914-917
ISSN
  • 0028-0836 (ISSN-L)
  • 1476-4687
DOI
10.1038/nature716
OpenAlex
W2151364836
Cited by
365
References
1
FWCI
10.04
Type
journal article
Language
en
Open access
closed
Licence
www.springer.com/tdm (tdm)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Hox protein mutation and macroevolution of the insect body plan. https://app.cochat.ai/papers/10.1038/nature716
The paper
Ronshaugen, M., McGinnis, N., & McGinnis, W. (2002). Hox protein mutation and macroevolution of the insect body plan. Nature. https://doi.org/10.1038/nature716

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.