Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity

Garinis, George A., Uittenboogaard, Lieneke M., Stachelscheid, Heike, Fousteri, Maria, van Ijcken, Wilfred, Breit, Timo M., van Steeg, Harry, Mullenders, Leon H. F. +5 more·2009·Nature Cell Biology

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Items 101–137 of 137

  1. XPF interacts with TOP2B for R-loop processing and DNA looping on actively transcribed genes
    Georgia Chatzinikolaou, Kalliopi Stratigi, Athanasios Siametis, Evi Goulielmaki, Alexia Akalestou-Clocher, Ioannis Tsamardinos, Pantelis Topalis, Caroline A. Austin, Britta A. M. Bouwman, Nicola Crosetto et al. · 2023 · Science Advances
  2. Effects of compound heterozygosity at the Xpd locus on cancer and ageing in mouse models
    Marieke van de Ven, Jaan‐Olle Andressoo, Gijsbertus T. J. van der Horst, Jan H.J. Hoeijmakers, James R. Mitchell · 2012 · DNA repair
  3. Targeting transcription-coupled nucleotide excision repair overcomes resistance in chronic lymphocytic leukemia
    Gregor Lohmann, Elena L. Vasyutina, Johannes Bloehdorn, Nina Reinart, Jennifer I. Schneider, V. V. Suresh Babu, Gero Knittel, Giuliano Crispatzu, Petra Mayer, Christian Prinz et al. · 2016 · Leukemia
  4. Perinatal Obesity Sensitizes for Premature Kidney Aging Signaling
    Jaco Selle, K. Bohl, K. Höpker, R. Wilke, K. Dinger, P. Kasper, B. Abend, B. Schermer, R. Müller, C. Kurschat et al. · 2023 · International Journal of Molecular Sciences
  5. Decreased hepatic thyroid hormone signaling in systemic and liver-specific but not brain-specific accelerated aging due to DNA repair deficiency in mice
    Sander Barnhoorn, Marcel E. Meima, Robin Patrick Peeters, Veerle Darras, Selmar Leeuwenburgh, Jan H.J. Hoeijmakers, Wilbert P. Vermeij, W. Edward Visser · 2023 · European Thyroid Journal
  6. Improved health by combining dietary restriction and promoting muscle growth in DNA repair‐deficient progeroid mice
    Wilbert P. Vermeij, Khalid Alyodawi, Ivar van Galen, Jennie L. Von der Heide, María B. Birkisdóttir, Lisanne J. van’t Sant, Rutger A. Ozinga, Daphne S. J. Komninos, Kimberly Smit, Yvonne Rijksen et al. · 2024 · Journal of Cachexia Sarcopenia and Muscle
  7. Loss of Ercc1 Results in a Time- and Dose-Dependent Reduction of Proliferating Early Hematopoietic Progenitors
    Judith Verhagen-Oldenampsen, Jurgen R. Haanstra, Paulina M. H. van Strien, Marijke G. Valkhof, Ivo P. Touw, Marieke v. Lindern · 2012 · Anemia
  8. Relationship Between DNA Damage and Energy Metabolism: Evidence from DNA Repair Deficiency Syndromes
    Sarah C. Vose, James R. Mitchell · 2011 · InTech eBooks
  9. Omics Approaches for Identifying Physiological Adaptations to Genome Instability in Aging
    Diletta Edifizi, Björn Schumacher · 2017 · International Journal of Molecular Sciences
  10. Nuclear DNA Damage and Ageing
    Kyriacos Agathangelou, Zisis Apostolou, George A. Garinis · 2018 · Sub-cellular biochemistry/Subcellular biochemistry
  11. Longevity through DNA damage tolerance
    Laia Castells‐Roca, Michael M Mueller, Björn Schumacher · 2015 · Cell Cycle
  12. Life can be stressful without ATR
    Mark O’Driscoll · 2009 · Nature Genetics
  13. Research Progress on Aging Mechanisms
    Qiang Wang, Fengjuan Zhou, Wenmei Xie, Xiaorong Zhao, Xuan Liu · 2016 · Advances in Aging Research
  14. Active transcriptomic and proteomic reprogramming in theC. elegansnucleotide excision repair mutant xpa-1
    Henok Kassahun, Hilde Loge Nilsen · 2013 · Worm
  15. Hormesis running hot and cold
    Arturo Bujarrabal-Dueso, Björn Schumacher · 2016 · Cell Cycle
  16. In memoriam Olivier Toussaint – Stress-induced premature senescence and the role of DNA damage
    Alexander Bürkle · 2017 · Mechanisms of Ageing and Development
  17. From Genome to Geroscience: How DNA Damage Shapes Systemic Decline
    Athanasios Siametis, George A. Garinis · 2025 · BioEssays
  18. Nucleotide ExcisionRepair in Caenorhabditiselegans
    Hannes Lansand, Wim Vermeulen · 2011
  19. Genome Stability in Caenorhabditis elegans
    Matthias Rieckher, Amanda Franqueira Cardoso Lopes, Björn Schumacher · 2016 · Elsevier eBooks
  20. Aberrant DNA glycosylase-initiated repair pathway of free radicals in-duced DNA damage: implications for age-related diseases and natural aging
    Bakhyt T. Matkarimov, Murat K. Saparbaev · 2017 · Biopolymers and Cell
  21. Inactivation of hepatic ATRX in Atrx Foxg1cre mice prevents reversal of aging-like phenotypes by thyroxine
    Megan E. Rowland, Yan Jiang, Frank Beier, Nathalie G. Bérubé · 2018 · Aging
  22. Genome stability in Caenorhabditis elegans
    Igor Kovalchuk · 2021 · Elsevier eBooks
  23. Molecular Mechanisms of Learning, Memory and Aging
    Nils Zuiderveen Borgesius · 2011
  24. The Omics of Aging
    Ismene Karakasilioti, Άννα Ιωαννίδου, George A. Garinis · 2014 · Wiley eBooks
  25. Consequences of Interstrand Crosslinks in Hematopoiesis: Tipping the balance between senescence and proliferation
    Judith Verhagen-Oldenampsen · 2013 · EUR Research Repository (Erasmus University Rotterdam)
  26. Fractal and textural analysis of nuclear chromatin structural complexity in postnatal development and aging
    Igor V. Pantic · 2013
  27. The insulin-like growth factor 1 axis in prognosis and treatment of breast cancer
    Hermien Hartog · 2014 · University of Groningen research database (University of Groningen / Centre for Information Technology)
  28. Developing Methods to Validate Tissue Specific Growth Hormone Receptor Knockout Mouse Models
    Meredith J. Sigman · 2011 · OhioLink ETD Center (Ohio Library and Information Network)
  29. A pedagogical strategy addressing an unmet need: Making the biology of aging an accessible part of interdisciplinary gerontology education
    David J. Waters, Gerald C. Hyner, Kenneth F. Ferraro · 2017 · Gerontology & Geriatrics Education
  30. Interactions between DNA damage and metabolism
    Ana Guevara · 2020
  31. Faculty Opinions recommendation of The thyroid hormone receptor β induces DNA damage and premature senescence.
    Pilar Santisteban · 2014 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  32. Faculty Opinions recommendation of UCHL3 Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling TDP1 Proteostasis.
    Scott H. Kaufmann · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  33. Additional file 2 of Fasting before living-kidney donation: effect on donor well-being and postoperative recovery: study protocol of a multicenter randomized controlled trial
    Christiaan A. J. Oudmaijer, Robert C. Minnee, Pol, R. A., van den Boogaard, W. M. C., Komninos, D. S. J., van de Wetering, J., van Heugten, M. H., Hoorn, E. J., Sanders, J. S. F., Jan H.J. Hoeijmakers et al. · 2022 · Figshare
  34. Additional file 3 of Fasting before living-kidney donation: effect on donor well-being and postoperative recovery: study protocol of a multicenter randomized controlled trial
    Christiaan A. J. Oudmaijer, Robert C. Minnee, Pol, R. A., van den Boogaard, W. M. C., Komninos, D. S. J., van de Wetering, J., van Heugten, M. H., Hoorn, E. J., Sanders, J. S. F., Jan H.J. Hoeijmakers et al. · 2022 · Figshare
  35. Additional file 1 of Fasting before living-kidney donation: effect on donor well-being and postoperative recovery: study protocol of a multicenter randomized controlled trial
    Christiaan A. J. Oudmaijer, Robert C. Minnee, Pol, R. A., van den Boogaard, W. M. C., Komninos, D. S. J., van de Wetering, J., van Heugten, M. H., Hoorn, E. J., Sanders, J. S. F., Jan H.J. Hoeijmakers et al. · 2022 · Figshare
  36. Facilitation of STK19 in transcription coupled nuclear excision repair (TC-NER): Mechanisms, interactions, and genome stability
    Sohom Naskar, Nitika Mahajan, Nawaneetan Sriraman, Ankita Sarkar, Koustav Sarkar · 2026 · Human Gene
  37. Mechanisms of spontaneous loss of heterozygosity in adult stem cells
    Lara Al-Zoubi · 2020 · theses.fr (ABES)