Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity
Garinis, George A., Uittenboogaard, Lieneke M., Stachelscheid, Heike, Fousteri, Maria, van Ijcken, Wilfred, Breit, Timo M., van Steeg, Harry, Mullenders, Leon H. F. +5 more·2009·Nature Cell Biology
DOI 10.1038/ncb1866
Cited by (137)
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- Perinatal Obesity Sensitizes for Premature Kidney Aging SignalingJaco Selle, K. Bohl, K. Höpker, R. Wilke, K. Dinger, P. Kasper, B. Abend, B. Schermer, R. Müller, C. Kurschat et al. · 2023 · International Journal of Molecular Sciences
- Decreased hepatic thyroid hormone signaling in systemic and liver-specific but not brain-specific accelerated aging due to DNA repair deficiency in miceSander Barnhoorn, Marcel E. Meima, Robin Patrick Peeters, Veerle Darras, Selmar Leeuwenburgh, Jan H.J. Hoeijmakers, Wilbert P. Vermeij, W. Edward Visser · 2023 · European Thyroid Journal
- Improved health by combining dietary restriction and promoting muscle growth in DNA repair‐deficient progeroid miceWilbert P. Vermeij, Khalid Alyodawi, Ivar van Galen, Jennie L. Von der Heide, María B. Birkisdóttir, Lisanne J. van’t Sant, Rutger A. Ozinga, Daphne S. J. Komninos, Kimberly Smit, Yvonne Rijksen et al. · 2024 · Journal of Cachexia Sarcopenia and Muscle
- Loss of Ercc1 Results in a Time- and Dose-Dependent Reduction of Proliferating Early Hematopoietic ProgenitorsJudith Verhagen-Oldenampsen, Jurgen R. Haanstra, Paulina M. H. van Strien, Marijke G. Valkhof, Ivo P. Touw, Marieke v. Lindern · 2012 · Anemia
- Relationship Between DNA Damage and Energy Metabolism: Evidence from DNA Repair Deficiency SyndromesSarah C. Vose, James R. Mitchell · 2011 · InTech eBooks
- Omics Approaches for Identifying Physiological Adaptations to Genome Instability in AgingDiletta Edifizi, Björn Schumacher · 2017 · International Journal of Molecular Sciences
- Nuclear DNA Damage and AgeingKyriacos Agathangelou, Zisis Apostolou, George A. Garinis · 2018 · Sub-cellular biochemistry/Subcellular biochemistry
- Longevity through DNA damage toleranceLaia Castells‐Roca, Michael M Mueller, Björn Schumacher · 2015 · Cell Cycle
- Life can be stressful without ATRMark O’Driscoll · 2009 · Nature Genetics
- Research Progress on Aging MechanismsQiang Wang, Fengjuan Zhou, Wenmei Xie, Xiaorong Zhao, Xuan Liu · 2016 · Advances in Aging Research
- Active transcriptomic and proteomic reprogramming in theC. elegansnucleotide excision repair mutant xpa-1Henok Kassahun, Hilde Loge Nilsen · 2013 · Worm
- Hormesis running hot and coldArturo Bujarrabal-Dueso, Björn Schumacher · 2016 · Cell Cycle
- In memoriam Olivier Toussaint – Stress-induced premature senescence and the role of DNA damageAlexander Bürkle · 2017 · Mechanisms of Ageing and Development
- From Genome to Geroscience: How DNA Damage Shapes Systemic DeclineAthanasios Siametis, George A. Garinis · 2025 · BioEssays
- Nucleotide ExcisionRepair in CaenorhabditiselegansHannes Lansand, Wim Vermeulen · 2011
- Genome Stability in Caenorhabditis elegansMatthias Rieckher, Amanda Franqueira Cardoso Lopes, Björn Schumacher · 2016 · Elsevier eBooks
- Aberrant DNA glycosylase-initiated repair pathway of free radicals in-duced DNA damage: implications for age-related diseases and natural agingBakhyt T. Matkarimov, Murat K. Saparbaev · 2017 · Biopolymers and Cell
- Inactivation of hepatic ATRX in Atrx Foxg1cre mice prevents reversal of aging-like phenotypes by thyroxineMegan E. Rowland, Yan Jiang, Frank Beier, Nathalie G. Bérubé · 2018 · Aging
- Genome stability in Caenorhabditis elegansIgor Kovalchuk · 2021 · Elsevier eBooks
- Molecular Mechanisms of Learning, Memory and AgingNils Zuiderveen Borgesius · 2011
- The Omics of AgingIsmene Karakasilioti, Άννα Ιωαννίδου, George A. Garinis · 2014 · Wiley eBooks
- Consequences of Interstrand Crosslinks in Hematopoiesis: Tipping the balance between senescence and proliferationJudith Verhagen-Oldenampsen · 2013 · EUR Research Repository (Erasmus University Rotterdam)
- Fractal and textural analysis of nuclear chromatin structural complexity in postnatal development and agingIgor V. Pantic · 2013
- The insulin-like growth factor 1 axis in prognosis and treatment of breast cancerHermien Hartog · 2014 · University of Groningen research database (University of Groningen / Centre for Information Technology)
- Developing Methods to Validate Tissue Specific Growth Hormone Receptor Knockout Mouse ModelsMeredith J. Sigman · 2011 · OhioLink ETD Center (Ohio Library and Information Network)
- A pedagogical strategy addressing an unmet need: Making the biology of aging an accessible part of interdisciplinary gerontology educationDavid J. Waters, Gerald C. Hyner, Kenneth F. Ferraro · 2017 · Gerontology & Geriatrics Education
- Interactions between DNA damage and metabolismAna Guevara · 2020
- Faculty Opinions recommendation of The thyroid hormone receptor β induces DNA damage and premature senescence.Pilar Santisteban · 2014 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Faculty Opinions recommendation of UCHL3 Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling TDP1 Proteostasis.Scott H. Kaufmann · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Additional file 2 of Fasting before living-kidney donation: effect on donor well-being and postoperative recovery: study protocol of a multicenter randomized controlled trialChristiaan A. J. Oudmaijer, Robert C. Minnee, Pol, R. A., van den Boogaard, W. M. C., Komninos, D. S. J., van de Wetering, J., van Heugten, M. H., Hoorn, E. J., Sanders, J. S. F., Jan H.J. Hoeijmakers et al. · 2022 · Figshare
- Additional file 3 of Fasting before living-kidney donation: effect on donor well-being and postoperative recovery: study protocol of a multicenter randomized controlled trialChristiaan A. J. Oudmaijer, Robert C. Minnee, Pol, R. A., van den Boogaard, W. M. C., Komninos, D. S. J., van de Wetering, J., van Heugten, M. H., Hoorn, E. J., Sanders, J. S. F., Jan H.J. Hoeijmakers et al. · 2022 · Figshare
- Additional file 1 of Fasting before living-kidney donation: effect on donor well-being and postoperative recovery: study protocol of a multicenter randomized controlled trialChristiaan A. J. Oudmaijer, Robert C. Minnee, Pol, R. A., van den Boogaard, W. M. C., Komninos, D. S. J., van de Wetering, J., van Heugten, M. H., Hoorn, E. J., Sanders, J. S. F., Jan H.J. Hoeijmakers et al. · 2022 · Figshare
- Facilitation of STK19 in transcription coupled nuclear excision repair (TC-NER): Mechanisms, interactions, and genome stabilitySohom Naskar, Nitika Mahajan, Nawaneetan Sriraman, Ankita Sarkar, Koustav Sarkar · 2026 · Human Gene
- Mechanisms of spontaneous loss of heterozygosity in adult stem cellsLara Al-Zoubi · 2020 · theses.fr (ABES)