Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60

Sun, Yingli, Jiang, Xiaofeng, Xu, Ye, Ayrapetov, Marina K., Moreau, Lisa A., Whetstine, Johnathan R., Price, Brendan D.·2009·Nature Cell Biology
DOI 10.1038/ncb1982

Cited by (455)

Items 401–455 of 455

  1. Dynamic balance of H3K9me2 heterochromatin by CoREST-2 and RE-1 in growing neurons
    José F. Drube, Andrés M. Cardozo Gizzi, Victoria Rozés‐Salvador, Imanol Martínez, Danilo G. Ceschin, Laureano Giordano, Lucas Serniotti, Laura Gastaldi, M. Virginia Remedi, Ana Lis Moyano et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  2. Interferon Dependent Immune Memory during HSV-1 Neuronal Latency Results in Increased H3K9me3 and Restriction of Reactivation by ATRX
    Abigail L. Whitford, Gaelle E Auguste, Alison K. Francois, Chris Boutell, Clint L. Miller, Sarah E. Dremel, Anna Ruth Cliffe · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  3. IDENTIFICATION OF NOVEL FANCD2 INTERACTING PROTEINS VIA IMMUNOPRECIPITATION AND MASS SPECTROMETRY
    Paul A. Azzinaro · 2014
  4. Spy1 Regulation of the DNA Damage Response; Checkpoint Activation and Cellular Senescence
    Espanta Jalili · 2013
  5. The regulation of RNA Polymerase I-mediated transcription in forebrain neurons.
    Scott C. Smith · 2012
  6. Altered DNA methylation of repetitive elements may explain the modified risk of cervical intraepithelial neoplasia (CIN) associated with genetic polymorphisms of the folate metabolic pathway in the US post folic acid fortification era
    Suguna Badiga · ProQuest Demo Repository
  7. COMMENTARY Cross Talk between Ubiquitination and Demethylation
    Xiaodong Huang, Vishva M. Dixit · 2016
  8. Familial and Somatic Mutations of Histone-Modifying Enzymes in Cancer
    Chenyi Liu, Lincoln David Stein · 2013 · Springer eBooks
  9. Biochemical and structural studies of dosage compensation members : MSL1, MSL3, and MOF from Drosophila melanogaster
    Kent Conrad Klemmer · 2010 · University Library - University of Saskatchewan (University of Saskatchewan)
  10. Defining a role for TPX2 in the nucleus – Regulation of the DNA damage response
    Gernot Neumayer · 2013 · Libraries and Cultural Resources (University of Calgary)
  11. Variation, Modification, and Reorganization of Broken Chromatin
    Timothy C. Humphrey, Jessica A. Downs, Anna L. Chambers · 2016 · Elsevier eBooks
  12. Structural and Functional Characterization of the Tip60 Chromodomain
    Sifa Arrafi · 2017 · HARVEST (University of Saskatchewan)
  13. Role of VHL in DNA double-strand break repair and genomic instability in renal cell carcinoma
    Julie L. Metcalf · 2013 · TSpace (University of Toronto)
  14. UHRF1 and the DNA Damage Response
    Helena Sumantrai Mistry · 2012 · TSpace (University of Toronto)
  15. The Molecular Basis of Histone Methylation
    Lidong Sun, Jia Fang · 2017 · Cancer drug discovery and develogment/Cancer drug discovery and development
  16. DNA and Histone Methylation in Brain Cancer
    S. C. Lee, Young Zoon Kim · 2017 · Cancer drug discovery and develogment/Cancer drug discovery and development
  17. Characterization of a H4K20ME2 Methyl-Binding Domain in the Fanconi Anemia Protein FANCD2
    Karissa L. Paquin · 2017
  18. The NuA4 acetyltransferase and non-canonical chromatin-associated MRN/ATM activity temporally define senescence-associated secretory programs
    Nicolas Malaquin, Audrey Carrier-Leclerc, Aurélie Martinez, Mireille Dessureault, Sabrina Ghadaouia, Jean‐Philippe Coppé, Stéphanie Nadeau, Guillaume B. Cardin, Judith Campisi, Françis Rodier · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  19. Nuevas funciones de la quinasa humana VRK1 en la respuesta al daño en el ADN y la estructura de la cromatina
    Ignacio Campillo Marcos · 2019
  20. Mitigation of Injury from Myocardial Infarction by TH1834, an Inhibitor of the Acetyltransferase Tip60
    Xinrui Wang, Tina C. Wan, Katherine Kulik, Amelia Lauth, Brian C. Smith, John Lough, John A. Auchampach · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  21. Faculty Opinions recommendation of Oncometabolites suppress DNA repair by disrupting local chromatin signalling.
    Sophie E. Polo, Beatrice Rondinelli · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  22. Faculty Opinions recommendation of TIP60 represses activation of endogenous retroviral elements.
    Cheng‐Ming Chiang · 2018 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  23. Oncometabolites, epigenetic marks, and DNA repair
    Jonathan Dow, Peter M. Glazer · 2022 · Elsevier eBooks
  24. DNA damage and histone modifications
    Hieu T. Van, Margarida Almeida Santos · 2022 · Elsevier eBooks
  25. RepairSwitch: simultaneous functional assessment of homologous recombination vs end joining DNA repair pathways in living cells
    Ruchama Chaya Steinberg, Jianyong Liu, Ajay M. Vaghasia, Hugh Giovinazzo, Minh‐Tam Pham, Dimitri Tselenchuk, Roshan V. Chikarmane, Michael C. Haffner, William G. Nelson, Srinivasan Yegnasubramanian · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  26. Reactive oxygen species-induced global DNA hypomethylation in bladder cancer is mediated via increased formation of 8-hydroxy-2'-deoxyguanosine
    Patcharawalai Whongsiri, Chanchai Boonla, Siriporn Chuchawankul, Depicha Jindatip · 2017
  27. The Role of Post-translational Modifications in Cancer
    Carson Cohen, Todd R. Lewis, Rongsheng E. Wang · 2025 · Springer eBooks
  28. Sperm H3K9me3 levels are associated with embryo developmental dynamics and biochemical pregnancy in IVF patients with normozoospermia
    Kaylee Holleman, Eva Sophie van Marion, Cindy Eleveld, Elise A. Ferreira, Maria P. H. Koster, Joop S.E. Laven, Willy M. Baarends, Raymond A. Poot, Esther B. Baart · 2025 · Reproductive Biology and Endocrinology
  29. Localisation et fonction de CHK2 en mitose
    Guillaume Chouinard · 2012 · Papyrus : Institutional Repository (Université de Montréal)
  30. Sirtuins as a Double-Edged Sword in Cancer: From Molecular Mechanisms to Therapeutic Opportunities
    Núria Sima, Laia Bosch‐Presegué, Alejandro Vaquero · 2014 · Springer eBooks
  31. Oncogenic chromodomain mutations allosterically impair TIP60 acetyltransfearse function preventing activation of DNA repair genes under genotoxic stress
    Himanshu Gupta, Aarushi Bansal, Ashish K. Gupta · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  32. Rôle du complexe Claspine-Timeless-Tipin dans le maintien de la stabilité du génome au cours de la réplication
    Julien N Bianco · 2010 · theses.fr (ABES)
  33. Unveiling the UFMylation Pathway: Implications in Neurodegenerative Diseases
    Yi-Rong Dong, Jin-Rong Wang, Yang Yang, Qiu-Zhu Chen, Yueqi Jiang, Xing Yang, Mei-Chuan Zhou, Shou-Peng Cao, Sen-Xiang Zeng, Caixia Zang et al. · 2026 · Journal of Molecular Biology
  34. Etude de la réparation des cassures double-brin de l'ADN dans les cellules souches du muscle squelettique et leurs progéniteurs
    Leyla Vahidi Ferdousi · 2014 · theses.fr (ABES)
  35. Comprendre et perturber le choix de la voie de réparation des cassures double brin de l'ADN pour augmenter l'efficacité et la sélectivité des agents anticancéreux génotoxiques
    Pauline Chanut · 2017 · theses.fr (ABES)
  36. Stabilité du génome et rôle des INGs dans la réponse aux dommages de l'ADN
    Audrey Mouche · 2017 · theses.fr (ABES)
  37. Le suppresseur de tumeur HIC1 est une nouvelle cible directe de la kinase ATM et un acteur multifonctionnel de la réponse cellulaire aux cassures double brin (DSBs) de l’ADN
    Sonia Paget · 2016 · theses.fr (ABES)
  38. UHRF1 inhibitors targeting the epigenetic patterns in cancer cells
    Liliyana Zaayter · 2018 · theses.fr (ABES)
  39. Role of thrombopoietin in DNA repair an genomic integrity in hematopoietic stem cells
    Daniela Barbieri · 2017 · theses.fr (ABES)
  40. Double strand break repair within constitutive heterochromatin
    Aikaterini Tsouroula · 2017 · theses.fr (ABES)
  41. Multiscale analysis of poly-ADP-ribosylation dependent chromatin remodeling mechanisms at DNA breaks
    Théo Lebeaupin · 2017 · theses.fr (ABES)
  42. DNA double-strand break formation and signalling in response to transcription-blocking topoisomerase I complexes
    Agnese Cristini · 2015 · theses.fr (ABES)
  43. Interaction mechanisms of epigenetic integrator UHRF1 with TIP60 acetyltransferase
    Waseem Ashraf · 2018 · theses.fr (ABES)
  44. Inhibition of UHRF1 protein by epigenetic partners and epi-drugs
    Tanveer Ahmad · 2019 · theses.fr (ABES)
  45. Maintien de l'hétérochromatine en réponse aux dommages à l'ADN dans des cellules de mammifères
    Anna Fortuny · 2019 · theses.fr (ABES)
  46. Role of Lamin B1 dysregulation in two Enabling Forces of Cancer : Genome Instability and Inflammation
    Paula Fontanilla-Ramirez · 2020 · theses.fr (ABES)
  47. Interplay between facultative heterochromatin and the DNA double-strand break repair response
    Enrico Pobega · 2023 · theses.fr (ABES)
  48. The Chromatin‐Modifying Protein RCOR2 / CoREST2 Safeguards Axon‐Dendrite Growth and Microtubule Stability in Brain Neurons
    Carlos Wilson, Victoria Rozés‐Salvador, José F. Drube, Andrés M. Cardozo Gizzi, Jerónimo Salguero, Ana Lis Moyano, Alfredo Cáceres · 2026 · Journal of Neurochemistry
  49. The RNA-binding protein RALY promotes ATM activation by stabilizing Tip60
    Bo Yao, Kailiang Zhao, Ning Yu, Ning Wang, Yinian Chang, Linzhu Luo, Fang Wang, Yide Mei · 2026 · Oncogene
  50. Nuclear amphiregulin and lamin A contribute to genomic stability and the response to replication stress via regulation of heterochromatin
    Tianqi Jiang, Aiman A. Zein, M.A. Christine Pratt · 2026 · Oncogene
  51. Chromatin Modifications Orchestrate DNA Repair Pathway Choice: Epigenetics Strategies for Enhancing CRISPR –Cas9‐Mediated Knock‐In Efficiency
    Xin Chen, Shan Qin, Ce Yang, Zhiyao Xing, Chong Liu, Xingchen Zhang, Xi Wu, Xueren Li, Yanhua Gong, Zichuan Liu · 2026 · Cell Proliferation
  52. Variation, modification, and reorganization of broken chromatin
    T.C. Humphrey, J.A. Downs, A.L. Chambers · 2016 · Elsevier eBooks
  53. Dynamic regulation of H3K9 modifications in cancer: pathogenesis and targeted therapies
    Yuanyuan Xu, Qihui Wu, Yuxiu Zhang, Jitong Zhao, Xiaodan Fu, Anqi Li, Yimin Li · 2026 · Biomarker Research
  54. Loss of KAT5-dependent H2A.Z acetylation provokes chromosomal instability in recurrent pregnancy loss
    Shilei Bi, Yongjie Chen, Lizi Zhang, Jiahui Zhang, Yijing Wang, Baoying Huang, Shanze Li, Lijun Huang, Yifan Wang, Huarong Wang et al. · 2026 · Science Advances
  55. Rational Design, Synthesis, and Evaluation of Inhibitors for the HIV-1 TAT Interacting Protein Tip60
    Liza Ngo · 2022 · Digital Archive @ GSU