Telomerase directly regulates NF-κB-dependent transcription

Ghosh, Arkasubhra, Saginc, Gaye, Leow, Shi Chi, Khattar, Ekta, Shin, Eun Myong, Yan, Ting Dong, Wong, Marc, Zhang, Zhizhuo +7 more·2012·Nature Cell Biology

DOI 10.1038/ncb2621

Cited by (378)

Items 201–300 of 378

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Telomerase activity in the occurrence and progression of oral squamous cell carcinoma
Yuji Miyazaki, Noriaki Yoshida, Tadashige Nozaki, Harumi Inoue, Kentaro Kikuchi, Kaoru Kusama · 2015 · Journal of Oral Science
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Telomerase Biogenesis and Activities from the Perspective of Its Direct Interacting Partners
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Human Telomerase Reverse Transcriptase Promotes the Epithelial to Mesenchymal Transition in Lung Cancer Cells by Enhancing c-MET Upregulation
Ram Raj Prasad, Deepak Kumar Mishra, Manoj Kumar, Pramod Kumar Yadava · 2021 · Heliyon
Exosomal telomerase transcripts reprogram the microRNA transcriptome profile of fibroblasts and partially contribute to CAF formation
Daniela Likonen, Maria Pinchasi, Einat Beery, Zinab Sarsor, Lorenzo Federico Signorini, Asia Gervits, Roded Sharan, Meir Lahav, Pia Raanani, Orit Uziel · 2022 · Scientific Reports
Triptolide inhibits transcription of hTERT through down-regulation of transcription factor specificity protein 1 in primary effusion lymphoma cells
Cong Long, Jingchao Wang, Wei Guo, Huan Wang, Chao Wang, Yu Liu, Xiaoping Sun · 2015 · Biochemical and Biophysical Research Communications
TERT rs2736100T/G polymorphism upregulates interleukin 6 expression in non-small cell lung cancer especially in adenocarcinoma
Fuxia Wang, Ping Fu, Yixin Pang, Chengxiang Liu, Zhulin Shao, Jingyan Zhu, Jie Li, Ti Wang, Xia Zhang, Jie Liu · 2014 · Tumor Biology
Telomerase reverse transcriptase induced thyroid carcinoma cell proliferation through PTEN/AKT signaling pathway
Hao Zhang, Ning Hu · 2018 · Molecular Medicine Reports
Inflammation-associated genomic instability in cancer
Khian Hong Pua, Chen Li Chew, David Philip Lane, Vinay Tergaonkar · 2019 · Genome Instability & Disease
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Short and dysfunctional telomeres protect from allergen‐induced airway inflammation
Sergio Piñeiro‐Hermida, Paula Martínez, Marı́a A. Blasco · 2021 · Aging Cell
Overexpression of the telomerase holoenzyme induces EMT and tumorigenesis of HPV‐immortalized keratinocytes
Aibing Wang, Dan Zhou, Ewa Krawczyk, Tuanjie Li, Vera Simić, Jie Li Lu, Xuefeng Liu, Richard Schlegel, Hang Yuan · 2023 · Journal of Medical Virology
Genes directly regulated by NF-κB in human hepatocellular carcinoma HepG2
Wei Dai, Jian Wu, Shuyan Zhang, Bingjie Shi, Xinhui Xu, Danyang Wang, Jinke Wang · 2017 · The International Journal of Biochemistry & Cell Biology
NF-κB promotes the stem-like properties of leukemia cells by activation of LIN28B
Jianbiao Zhou, Jing-Yuan Chooi, Ying Qing Ching, Jessie Yiying Quah, Sabrina Hui Min Toh, Yvonne Ng, Tuan Zea Tan, Wee Joo Chng · 2018 · World Journal of Stem Cells
Eukaryotic initiation factor 3, subunit C silencing inhibits cell proliferation and promotes apoptosis in human ovarian cancer cells
Fang Wen, Zhang-Ying Wu, Lei Nie, Qi-Zhu Zhang, Yuankun Qin, Zunlun Zhou, Jin-Jian Wu, Xing Zhao, Jun Rong Tan, Darrell R. Sawmiller et al. · 2019 · Bioscience Reports
TERT Expression Induces Resistance to BRAF and MEK Inhibitors in BRAF-Mutated Melanoma In Vitro
Julie Delyon, A. Vallet, Mélanie Bernard-Cacciarella, Isabelle Kuzniak, Coralie Reger de Moura, Baptiste Louveau, Fanélie Jouenne, Samia Mourah, Célèste Lebbé, Nicolas Dumaz · 2023 · Cancers
TERT upregulation promotes cell proliferation via degradation of p21 and increases carcinogenic potential
Masako Mishima, Atsushi Takai, Haruhiko Takeda, Eriko Iguchi, Shigeharu Nakano, Yosuke Fujii, Masayuki Ueno, Takahiko Ito, Mari Teramura, Yuji Eso et al. · 2024 · The Journal of Pathology
The associations of TERT-CLPTM1L variants and TERT mRNA expression with the prognosis of early stage non-small cell lung cancer
Z Chen, J Wang, Yun Bai, Shan Wang, Xiaojian Yin, J Xiang, Xiaoiao Li, Meian He, X Zhang, Tangchun Wu et al. · 2016 · Cancer Gene Therapy
PINX1 and TERT Are Required for TNF-α–Induced Airway Smooth Muscle Chemokine Gene Expression
Karl Deacon, Alan J. Knox · 2018 · The Journal of Immunology
Telomerase is required for glomerular renewal in kidneys of adult mice
Margo Montandon, Tynhinane Hamidouche, Lucile Yart, Lou C. Duret, Catherine Pons, Nicolas Soubeiran, Mélanie Pousse, Ludovic Cervera, Valérie Vial, Julien Fassy et al. · 2022 · npj Regenerative Medicine
Role of Telomeres and Telomerase in Parkinson's Disease—A New Theranostics?
Balachandar Vellingiri, Kiruthika Balasubramani, Mahalaxmi Iyer, Neethu Raj, Ajay Elangovan, Kwonwoo Song, Han Cheol Yeo, Namitha Jayakumar, Masako Kinoshita, Thangarasu Ravimanickam et al. · 2023 · Advanced Biology
Association of TERT Polymorphisms with Clinical Outcome of Non-Small Cell Lung Cancer Patients
Xueying Zhao, Shiming Wang, Junjie Wu, Xiaoying Li, Xun Wang, Zhiqiang Gao, Wenting Wu, Haijian Wang, Jiucun Wang, Ji Qian et al. · 2015 · PLoS ONE
Telomere length in peripheral blood lymphocytes related to genetic variation in telomerase, prognosis and clinicopathological features in breast cancer patients
Michal Kroupa, Sivaramakrishna P. Rachakonda, Veronika Polakova Vymetalkova, Kristýna Tomášová, Václav Liška, Soňa Vodenková, Andrea Čumová, Andrea Rössnerová, Ľudmila Vodičková, Kari Hemminki et al. · 2020 · Mutagenesis
TERT Promoter Mutations Increase Sense and Antisense Transcription from the TERT Promoter
François Hafezi, Lisa Jaxel, Morgane Lemaire, Jonathan D. Turner, Danielle Perez-Bercoff · 2021 · Biomedicines
Telomere Reprogramming and Cellular Metabolism: Is There a Link?
Maria P. Rubtsova, Д. А. Никишин, M. Yu. Vyssokikh, Maria S. Koriagina, Andrey V. Vasiliev, Olga А. Dontsova · 2024 · International Journal of Molecular Sciences
Geographic and Viral Etiology Patterns of TERT Promoter and CTNNB1 Exon 3 Mutations in Hepatocellular Carcinoma: A Comprehensive Review
Mariana Leonardo Terra, Thaís Barbosa Ferreira Sant’Anna, José Júnior França de Barros, Natalia Motta Araujo · 2025 · International Journal of Molecular Sciences
The Regulation of ROS‐ and BECN1‐Mediated Autophagy by Human Telomerase Reverse Transcriptase in Glioblastoma
Xuelu Ding, Ziyang Nie, Zhaoyuan She, Xue Bai, Qiuhui Yang, Feng Wang, Fei Wang, Xin Geng · 2021 · Oxidative Medicine and Cellular Longevity
TERT Promoter Mutations and rs2853669 Polymorphism: Useful Markers for Clinical Outcome Stratification of Patients With Oral Cavity Squamous Cell Carcinoma
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Relationship between telomere length and the prognosis of breast cancer based on estrogen receptor status: A Mendelian randomization study
Yilun Li, Li Ma · 2022 · Frontiers in Oncology
Tert promotes cardiac regenerative repair after MI through alleviating ROS-induced DNA damage response in cardiomyocyte
Xiaomin Wei, Yilin Zhou, Enge Shao, Xiaoran Shi, Yuan Han, Yeshen Zhang, Guoquan Wei, Hao Zheng, Senlin Huang, Yanmei Chen et al. · 2024 · Cell Death Discovery
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Gabriele Christine Saretzki · 2022 · Stem Cells
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Short-Term TERT Inhibition Impairs Cellular Proliferation via a Telomere Length-Independent Mechanism and Can Be Exploited as a Potential Anticancer Approach
Aamir Amin, Marzia Morello, Maria Raffaella Petrara, Beatrice Rizzo, Francesco Argenton, Anita De Rossi, Silvia Giunco · 2023 · Cancers
Noncanonical functions of telomerase and telomeres in viruses‐associated cancer
Sara Rasouli, Aleksandra Dakic, Qi‐En Wang, Darrion Mitchell, Dukagjin M. Blakaj, Nagireddy Putluri, Jenny Li, Xuefeng Liu · 2024 · Journal of Medical Virology
Non-Canonical TERT Activity Initiates Osteogenesis in Calcific Aortic Valve Disease
Cuevas, Rolando A., Hortells, Luis, Chu, Claire C., Wong, Ryan, Crane, Alex, Boufford, Camille K., Regan, Cailyn, Moorhead, William J., Bashline, Michael J., Parwal, Aneesha et al. · 2025 · Circulation Research
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Jessica Marinaccio, Erica Rossi, Emanuela Micheli, Ion Udroiu, Nicoló Baranzini, Gaia Marcolli, Antonella Sgura · 2025 · PLoS Genetics
Molecular and immunological paradigms of hepatocellular carcinoma: Special reference to therapeutic approaches
Ayano Kabashima, Shu Shimada, Masahiro Shimokawa, Yoshimitsu Akiyama, Minoru Tanabe, Shinji Tanaka · 2020 · Journal of Hepato-Biliary-Pancreatic Sciences
SIRT1 regulates the localization and stability of telomerase protein by direct interaction
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Yongpeng Zhang, Caiyun Zhang, Chunlei Zhang, Xueqiong Bin, Jinghan Jiang, Changbao Huang · 2023 · Journal of Psychiatric Research
Telomerase inhibitors induce mitochondrial oxidation and DNA damage-dependent cell death rescued by Bcl-2/Bcl-xL
Aparna Geetha Jayaprasad, Aneesh Chandrasekharan, Srinivas Jyothi, S.M. John Sam, Thankayyan Retnabai Santhoshkumar, M. Radhakrishna Pillai · 2024 · International Journal of Biological Macromolecules
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Donald K. E. D. Detchou, Umaru Barrie · 2024 · Neurosurgical Review
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Zhiqian Zhang, Changli Zhong, Taixian Yuan, Xiaoyan Zhou, Min Zhao, Husun Qian, Wei Cheng, Tingmei Chen · 2018 · Methods and Applications in Fluorescence
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Interleukin 8 is a biomarker of telomerase inhibition in cancer cells
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Zane Svikle, Leonora Pahirko, Līga Zariņa, Kristīne Baumane, Deimantė Kardonaitė, Lina Radzevičienė, Laura Daugintytė-Petrušienė, Vilma Jūratė Balčiūnienė, Rasa Verkauskienė, Angelina Tiščuka et al. · 2022 · Journal of Clinical Medicine
TERT inhibition leads to reduction of IL ‐6 expression induced by palmitic acid and interferes with the protective effects of tibolone in an astrocytic cell model
Yeimy González‐Giraldo, Angie V. Garzón‐Benitez, Diego A. Forero, George Emilio Barreto · 2019 · Journal of Neuroendocrinology
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Fang Zhou, Hongjun Wei, Aiping Ding, Wensheng Qiu, Lingxin Feng, Quan Zhou, Jun Liang, Lu Yue · 2013 · Clinical and Translational Science
Helicobacter pylori Induces a Novel NF-kB/LIN28A/let-7a/hTERT Axis to Promote Gastric Carcinogenesis
Shen Li, Jiping Zeng, Lin Ma, Shuyan Li, Chunyan Chen, Jihui Jia, Xiuming Liang · 2020 · Molecular Cancer Research
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Pam S. Ellis, Raquel Rua Martins, Emily J Thompson, Asma Farhat, Stephen A. Renshaw, Catarina Martins Henriques · 2022 · Immunity & Ageing
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Vasileios Kordinas, George I. Tsirpanlis, Chryssoula Nicolaou, Margarita Zoga, Anastasios Ioannidis, Vasiliki Ioannidou, Sotiris Bersimis, Christina Petrihou, Lefkothea Savva, N.J. Legakis et al. · 2015 · Cellular & Molecular Biology Letters
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Telomere length sensitive regulation of interleukin receptor 1 type 1 (IL1R1) by the shelterin protein TRF2 modulates immune signalling in the tumour microenvironment
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TERT expression is associated with metastasis from thin primaries, exhausted CD4+ T cells in melanoma and with DNA repair across cancer entities
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Pharmacological preconditioning by TERT inhibitor BIBR1532 confers neuronal ischemic tolerance through TERT‐mediated transcriptional reprogramming
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Telomere length sensitive regulation of interleukin receptor 1 type 1 (IL1R1) by the shelterin protein TRF2 modulates immune signalling in the tumour microenvironment
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PITX1 protein interacts with ZCCHC10 to regulate hTERT mRNA transcription
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