ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death

Han, Jaeseok, Back, Sung Hoon, Hur, Junguk, Lin, Yu-Hsuan, Gildersleeve, Robert, Shan, Jixiu, Yuan, Celvie L., Krokowski, Dawid +5 more·2013·Nature Cell Biology

Cited by (1,000)

Items 301–400 of 1,000

  1. Chop / Ddit3 depletion in β cells alleviates ER stress and corrects hepatic steatosis in mice
    Jing Yong, Vishal S. Parekh, Shannon M. Reilly, Jonamani Nayak, Zhouji Chen, Cynthia Lebeaupin, Insook Jang, Jiangwei Zhang, Thazha P. Prakash, Hong Sun et al. · 2021 · Science Translational Medicine
  2. ATP increases within the lumen of the endoplasmic reticulum upon intracellular Ca2+release
    Neelanjan Vishnu, Muhammad Jadoon Khan, Felix Karsten, Lukas N. Groschner, Markus Waldeck‐Weiermair, René Rost, Seth Hallström, Hiromi Imamura, Wolfgang F. Graier, Roland Malli · 2013 · Molecular Biology of the Cell
  3. At the Crossing of ER Stress and MAMs: A Key Role of Sigma-1 Receptor?
    Benjamin Delprat, Lucie Crouzier, Tsung‐Ping Su, Tangui Maurice · 2019 · Advances in experimental medicine and biology
  4. Activation of volume-sensitive outwardly rectifying chloride channel by ROS contributes to ER stress and cardiac contractile dysfunction: involvement of CHOP through Wnt
    Mingzhi Shen, Lin Qi Wang, B Wang, T Wang, Guodong Yang, Liangliang Shen, T Wang, Xiaolan Guo, Ying Liu, Yunlong Xia et al. · 2014 · Cell Death and Disease
  5. Expression of the Neuronal tRNA n-Tr20 Regulates Synaptic Transmission and Seizure Susceptibility
    Mridu Kapur, Archan Ganguly, Gabor Nagy, Scott I. Adamson, Jeffrey H. Chuang, Wayne N. Frankel, Susan L. Ackerman · 2020 · Neuron
  6. Mitochondrial dysfunction abrogates dietary lipid processing in enterocytes
    Chrysanthi Moschandrea, Vangelis Kondylis, Ioannis Evangelakos, Marija Herholz, Farina Schneider, Christina Schmidt, Ming Hui Yang, Sandra Ehret, Markus Heine, Michelle Y. Jaeckstein et al. · 2023 · Nature
  7. Regulatory crosstalk within the mammalian unfolded protein response
    Joseph W. Brewer · 2013 · Cellular and Molecular Life Sciences
  8. The Emerging Roles of Viroporins in ER Stress Response and Autophagy Induction during Virus Infection
    To Sing Fung, Jaume Torres, Ding Xiang Liu · 2015 · Viruses
  9. Up-regulation of endoplasmic reticulum stress induced genes of the unfolded protein response in the liver of periparturient dairy cows
    Denise K. Geßner, Gloria Schlegel, Robert Ringseis, F. J. Schwarz, Klaus Eder · 2014 · BMC Veterinary Research
  10. Unfolded protein response in hepatitis C virus infection
    Shiu‐Wan Chan · 2014 · Frontiers in Microbiology
  11. Protein synthesis inhibition and GADD34 control IFN‐β heterogeneous expression in response to dsRNA
    Alexandre Dalet, Rafael José Argüello, Alexis J. Combes, Lionel Spinelli, Sébastien Jaeger, Mathieu Fallet, Thien‐Phong Vu Manh, Andreia V. Mendes, Jessica Perego, Marisa Reverendo et al. · 2017 · The EMBO Journal
  12. The eIF2α Kinase GCN2 Modulates Period and Rhythmicity of the Circadian Clock by Translational Control of Atf4
    Salil Saurav Pathak, Dong Liu, Tianbao Li, Nuria de Zavalía, Lei Zhu, Jin Li, Karthikeyan Ramanujam, Tommy Alain, Andrew C. Liu, Kai-Florian Storch et al. · 2019 · Neuron
  13. Sestrin2: multifaceted functions, molecular basis, and its implications in liver diseases
    Chunfeng Lu, Yiming Jiang, Wenxuan Xu, Xiaofeng Bao · 2023 · Cell Death and Disease
  14. Cellular Dormancy in Cancer: Mechanisms and Potential Targeting Strategies
    Hye-Young Min, Ho‐Young Lee · 2023 · Cancer Research and Treatment
  15. Endoplasmic reticulum stress in hepatic steatosis and inflammatory bowel diseases
    Beichu Guo, Zihai Li · 2014 · Frontiers in Genetics
  16. FET family fusion oncoproteins target the SWI/SNF chromatin remodeling complex
    Malin Lindén, Christer Thomsen, Pernilla Grundevik, Emma Jonasson, Daniel Andersson, Rikard Runnberg, Soheila Dolatabadi, Christoffer Vannas, Manuel Luna Santamaría, Henrik Fagman et al. · 2019 · EMBO Reports
  17. Proteomics Reveals Scope of Mycolactone-mediated Sec61 Blockade and Distinctive Stress Signature
    Jean‐David Morel, Anja Paatero, Jiajie Wei, Jonathan Wilson Yewdell, Laure Guenin‐Macé, Delphi Van Haver, Francis Impens, Natalia Pietrosemoli, Ville O. Paavilainen, Caroline Demangel · 2018 · Molecular & Cellular Proteomics
  18. Sodium butyrate mitigates type 2 diabetes by inhibiting PERK-CHOP pathway of endoplasmic reticulum stress
    Yimeng Hu, Jie Liu, Yin Yuan, Jing Chen, Siyuan Cheng, Huawei Wang, Yancheng Xu · 2018 · Environmental Toxicology and Pharmacology
  19. Pyroptosis in the Retinal Neurovascular Unit: New Insights Into Diabetic Retinopathy
    Chunren Meng, Chufeng Gu, Shuai He, Tong Su, Thashi Lhamo, Deji Draga, Qinghua Qiu · 2021 · Frontiers in Immunology
  20. Farnesol activates the intrinsic pathway of apoptosis and the ATF4-ATF3-CHOP cascade of ER stress in human T lymphoblastic leukemia Molt4 cells
    Joung Hyuck Joo, Eiichiro Ueda, Carl D. Bortner, Xiao-Ping Yang, Grace Liao, Anton M. Jetten · 2015 · Biochemical Pharmacology
  21. Modulation of the unfolded protein response impedes tumor cell adaptation to proteotoxic stress: a PERK for hepatocellular carcinoma therapy
    Yves‐Paul Vandewynckel, Debby Laukens, Eliene Bogaerts, Annelies Paridaens, Anja Van den Bussche, Xavier Verhelst, Christophe Van Steenkiste, Benedicte Descamps, Christian Vanhove, Louis J. Libbrecht et al. · 2014 · Hepatology International
  22. Proteotoxic Stress and Cell Death in Cancer Cells
    Claudio Brancolini, Luca Iuliano · 2020 · Cancers
  23. Chronic stress disrupts the homeostasis and progeny progression of oligodendroglial lineage cells, associating immune oligodendrocytes with prefrontal cortex hypomyelination
    Alexandros G. Kokkosis, Miguel M. Madeira, Matthew Mullahy, Stella E. Tsirka · 2022 · Molecular Psychiatry
  24. 25-Hydroxycholesterol Activates the Integrated Stress Response to Reprogram Transcription and Translation in Macrophages
    Norihito Shibata, Aaron F. Carlin, Nathanael J. Spann, Kaoru Saijo, Christopher S. Morello, Jeffrey G. McDonald, Casey E. Romanoski, Mano Ram Maurya, Minna Unelma Kaikkonen, Michael T. Y. Lam et al. · 2013 · Journal of Biological Chemistry
  25. Insights into the Molecular Mechanisms of NRF2 in Kidney Injury and Diseases
    Da-Wei Lin, Yung‐Chien Hsu, Cheng‐Chih Chang, Ching‐Chuan Hsieh, Chun‐Liang Lin · 2023 · International Journal of Molecular Sciences
  26. tRF-Gln-CTG-026 ameliorates liver injury by alleviating global protein synthesis
    Sunyang Ying, Pengcheng Li, Jiaqiang Wang, Kaiqiong Chen, Yu Zou, Moyu Dai, Kai Xu, Guihai Feng, Changjian Zhang, Haiping Jiang et al. · 2023 · Signal Transduction and Targeted Therapy
  27. Mitochondrial dysfunction induces SESN 2 gene expression through Activating Transcription Factor 4
    Alisa A. Garaeva, Irina E. Kovaleva, Peter M. Chumakov, Alexandra G. Evstafieva · 2016 · Cell Cycle
  28. Pleiotropic Effects of Tocotrienols and Quercetin on Cellular Senescence: Introducing the Perspective of Senolytic Effects of Phytochemicals
    Malavolta, Marco, Pierpaoli, Elisa, Giacconi, Robertina, Costarelli, Laura, Piacenza, Francesco, Basso, Andrea, Cardelli, Maurizio, Provinciali, Mauro · 2016 · Current Drug Targets
  29. Reactivation of cAMP Pathway by PDE4D Inhibition Represents a Novel Druggable Axis for Overcoming Tamoxifen Resistance in ER-positive Breast Cancer
    Rasmi Rekha Mishra, Nevin Belder, Suhail A. Ansari, Merve Kayhan, Hilal Bal, Umar Raza, Pelin Gulizar Ersan, Ünal Metin Tokat, Erol Eyüpoğlu, Özge Saatci et al. · 2018 · Clinical Cancer Research
  30. OMA1 mediates local and global stress responses against protein misfolding in CHCHD10 mitochondrial myopathy
    Mario Karam Shammas, Xiaoping Huang, Beverly P Wu, Evelyn Fessler, Insung Y. Song, Nicholas Randolph, Yan Li, Christopher K. E. Bleck, Danielle Springer, Carl Fratter et al. · 2022 · Journal of Clinical Investigation
  31. Oxidative Stress: A Suitable Therapeutic Target for Optic Nerve Diseases?
    Francesco Buonfiglio, Elsa Wilma Böhm, Norbert Pfeiffer, Adrian Gericke · 2023 · Antioxidants
  32. 3D reconstruction of murine mitochondria reveals changes in structure during aging linked to the MICOS complex
    Zer Vue, Edgar Garza Lopez, Kit Neikirk, Prasanna Katti, Larry Vang, Heather K. Beasley, Jianqiang Shao, Andrea Gail Marshall, Amber Crabtree, Alexandria C. Murphy et al. · 2023 · Aging Cell
  33. Mammalian integrated stress responses in stressed organelles and their functions
    Hao-jun Lu, Nirmala Koju, Rui Sheng · 2024 · Acta Pharmacologica Sinica
  34. ATF5 regulates β-cell survival during stress
    Christine A. Juliana, Juxiang Yang, Andrea V. Rozo, Austin L. Good, David Groff, Shu-Zong Wang, Michael R. Green, Doris A. Stoffers · 2017 · Proceedings of the National Academy of Sciences
  35. Nanosecond Pulsed Electric Fields Induce Endoplasmic Reticulum Stress Accompanied by Immunogenic Cell Death in Murine Models of Lymphoma and Colorectal Cancer
    Alessandra Rossi, Olga N. Pakhomova, Peter A. Mollica, Maura Casciola, Uma M. Mangalanathan, Andrei G. Pakhomov, Claudia Muratori · 2019 · Cancers
  36. Endoplasmic Reticulum Stress Signaling and the Pathogenesis of Hepatocarcinoma
    Juncheng Wei, Deyu Fang · 2021 · International Journal of Molecular Sciences
  37. The Unfolded Protein Responses in Health, Aging, and Neurodegeneration: Recent Advances and Future Considerations
    Andrew P. K. Wodrich, Andrew W. Scott, Arvind Kumar Shukla, Brent T. Harris, Edward Giniger · 2022 · Frontiers in Molecular Neuroscience
  38. The Common Cellular Events in the Neurodegenerative Diseases and the Associated Role of Endoplasmic Reticulum Stress
    Soo‐Jeong Kim, Doo Kyung Kim, Seho Jeong, Jaemin Lee · 2022 · International Journal of Molecular Sciences
  39. Endoplasmic reticulum stress in diseases
    Yingying Liu, Chunling Xu, Renjun Gu, Ruiqin Han, Ziyun Li, Xianrong Xu · 2024 · MedComm
  40. Concerning influences of micro/nano plastics on female reproductive health: focusing on cellular and molecular pathways from animal models to human studies
    Hasti Balali, Ali Morabbi, Mohammad Karimian · 2024 · Reproductive Biology and Endocrinology
  41. Melatonin Relieves Busulfan-Induced Spermatogonial Stem Cell Apoptosis of Mouse Testis by Inhibiting Endoplasmic Reticulum Stress
    Yanhua Cui, Lipeng Ren, Bo Li, Jia Fang, Yuanxin Zhai, Xin He, Enqi Du, Yi‐Liang Miao, Jinlian Hua, Sha Peng · 2017 · Cellular Physiology and Biochemistry
  42. Mitoxantrone triggers immunogenic prostate cancer cell death via p53-dependent PERK expression
    Changlin Li, Hui Sun, Wei Wei, Qiuzi Liu, Ying Zhang, Ying Zhang, Fangchao Liu, Chenchen Li, Chenchen Li, Kaicheng Ying et al. · 2020 · Cellular Oncology
  43. Systematic Transmission Electron Microscopy‐Based Identification and 3D Reconstruction of Cellular Degradation Machinery
    Kit Neikirk, Zer Vue, Prasanna Katti, Ben I. Rodriguez, Salem Omer, Jianqiang Shao, Trace A. Christensen, Edgar Garza Lopez, Andrea Gail Marshall, Caroline B. Palavicino‐Maggio et al. · 2023 · Advanced Biology
  44. Endoplasmic Reticulum Stress in the Diabetic Kidney, the Good, the Bad and the Ugly
    Robyn A. Cunard · 2015 · Journal of Clinical Medicine
  45. Thrombospondin 1 protects pancreatic β-cells from lipotoxicity via the PERK–NRF2 pathway
    Daniel Andrade Cunha, Monia Cito, Per‐Ola Carlsson, Jean‐Marie Vanderwinden, Jeffery D. Molkentin, Marco Bugliani, Piero Marchetti, Decio Laks Eizirik, Miriam Cnop · 2016 · Cell Death and Differentiation
  46. An integrated stress response via PKR suppresses HER2+ cancers and improves trastuzumab therapy
    Cédric Darini, Nour Ghaddar, Catherine Chabot, Gloria Assaker, Siham Sabri, Shuo Wang, Jothilatha Krishnamoorthy, Marguerite Buchanan, Adriana Aguilar‐Mahecha, Bassam Abdulkarim et al. · 2019 · Nature Communications
  47. Herpesviruses and the Unfolded Protein Response
    Benjamin P. Johnston, Craig McCormick · 2019 · Viruses
  48. LncRNA GOLGA2P10 is induced by PERK/ATF4/CHOP signaling and protects tumor cells from ER stress-induced apoptosis by regulating Bcl-2 family members
    Mengzhi Wu, Tao Fu, Jin-Xi Chen, Yingying Lin, Jin-E Yang, Shi‐Mei Zhuang · 2020 · Cell Death and Disease
  49. Crosstalk between autophagy and insulin resistance: evidence from different tissues
    Asie Sadeghi, Maryam Niknam, Mohammad Amin Momeni‐Moghaddam, Maryam Shabani, Hamid Aria, Alireza Bastin, Maryam Teimouri, Reza Meshkani, Hamed Akbari · 2023 · European journal of medical research
  50. Ribosome Elongation Stall Directs Gene-specific Translation in the Integrated Stress Response
    Sara K. Young-Baird, Lakshmi Reddy Palam, Cheng Wu, Matthew S. Sachs, Ronald C. Wek · 2016 · Journal of Biological Chemistry
  51. Regulation of the unfolded protein response through ATF4 and FAM129A in prostate cancer
    Nora Pällmann, Marte Livgård, Martina Tesikova, Hatice Zeynep Nenseth, Erman Akkuş, Jørgen Sikkeland, Yixin Jin, Doğukan Koç, Omer F. Kuzu, Manohar Pradhan et al. · 2019 · Oncogene
  52. Unfolded protein response in colorectal cancer
    Jingjing Huang, Huayang Pan, Jinge Wang, Tong Wang, Xiaoyan Huo, Yong Ma, Zhao‐Yang Lu, Bei Sun, Hongchi Jiang · 2021 · Cell & Bioscience
  53. Acetylsalicylic acid and salicylic acid present anticancer properties against melanoma by promoting nitric oxide-dependent endoplasmic reticulum stress and apoptosis
    Priscila Ausina, Jéssica Ristow Branco, Thainá M. Demaria, Amanda M. Esteves, João Gabriel Bernardo Leandro, Alan Clavelland Ochioni, Ana Paula Miranda Mendonça, Fernando Lucas Palhano, Marcus Fernandes de Oliveira, Wassim G. Abou-Kheir et al. · 2020 · Scientific Reports
  54. RIPK1 promotes death receptor-independent caspase-8-mediated apoptosis under unresolved ER stress conditions
    Yann Estornes, Miguel Aguileta, C Dubuisson, J De Keyser, Vera Goossens, Kristof Kersse, Afshin Samali, Peter Vandenabeele, Mathieu J.M. Bertrand · 2014 · Cell Death and Disease
  55. A novel autoregulatory loop between the Gcn2-Atf4 pathway and L-Proline metabolism controls stem cell identity
    Cristina D’Aniello, Annalisa Fico, Laura Casalino, Ombretta Guardiola, Gabriele Di Napoli, Federica Cermola, Dario De Cesare, Rosarita Tatè, Gilda Cobellis, Eduardo Jorge Patriarca et al. · 2015 · Cell Death and Differentiation
  56. Chemical stresses fail to mimic the unfolded protein response resulting from luminal load with unfolded polypeptides
    Timothy Jan Bergmann, Ilaria Fregno, Fiorenza Fumagalli, Andrea Rinaldi, Francesco Bertoni, Paul J. Boersema, Paola Picotti, Maurizio Molinari · 2018 · Journal of Biological Chemistry
  57. Heme Oxygenases: Cellular Multifunctional and Protective Molecules against UV-Induced Oxidative Stress
    Shida Chen, Xiaoyu Wang, Muhammad Farrukh Nisar, Mao Lin, Julia Li Zhong · 2019 · Oxidative Medicine and Cellular Longevity
  58. Intra-tumoral hypoxia promotes CD8+ T cell dysfunction via chronic activation of integrated stress response transcription factor ATF4
    Coral del Mar Alicea Pauneto, Brian Riesenberg, Evelyn J. Gandy, Andrew S. Kennedy, Genevieve Clutton, Jessica W. Hem, Katie E. Hurst, Elizabeth G. Hunt, Jarred Michael Green, Brian C. Miller et al. · 2025 · Immunity
  59. Impairment of stress granule assembly via inhibition of the eIF2alpha phosphorylation sensitizes glioma cells to chemotherapeutic agents
    Fabrício de Almeida Souza Vilas Boas, Aristóbolo M. Silva, Lirlandia Pires Sousa, Kátia Maciel Lima, Juliana P. Vago, Lucas Felipe Fernandes Bittencourt, Arthur Estanislau Dantas, Dawidson Assis Gomes, Márcia Carvalho Vilela, Mauro Martins Teixeira et al. · 2016 · Journal of Neuro-Oncology
  60. Autophagy and cancer cell metabolism
    Cara M. Anderson, Kay F. Macleod · 2019 · International review of cytology
  61. Biomimetic Metal−Organic Frameworks as Targeted Vehicles to Enhance Osteogenesis
    Na Liang, Na Ren, Zhichao Feng, Zhaoyang Sun, Mengwei Dong, Wenhan Wang, Feng Liu, Chunhui Sun, Weijia Zhou, Zhiqing Xing et al. · 2022 · Advanced Healthcare Materials
  62. Sex differences in islet stress responses support female β cell resilience
    George P. Brownrigg, Yi Han Xia, Chieh Min Jamie Chu, Su Wang, Charlotte F. Chao, Jiashuo Aaron Zhang, Søs Skovsø, Evgeniy Panzhinskiy, Xiaoke Hu, James D. Johnson et al. · 2023 · Molecular Metabolism
  63. Transcription Factor ATF4 Induces NLRP1 Inflammasome Expression during Endoplasmic Reticulum Stress
    Andrea D’Osualdo, Veronica G. Anania, Kebing Yu, Jennie Rebecca Lill, Randal J. Kaufman, Shu‐ichi Matsuzawa, John C. Reed · 2015 · PLoS ONE
  64. Combination treatment with triptolide and hydroxycamptothecin synergistically enhances apoptosis in A549 lung adenocarcinoma cells through PP2A-regulated ERK, p38 MAPKs and Akt signaling pathways
    Guanmin Meng, Wei Wang, Kequn Chai, SUWEN YANG, Fangqiong Li, KAI JIANG · 2015 · International Journal of Oncology
  65. The endoplasmic reticulum: A hub of protein quality control in health and disease
    Lisa Vincenz‐Donnelly, Mark S. Hipp · 2017 · Free Radical Biology and Medicine
  66. Neuroprotection by eIF2α-CHOP inhibition and XBP-1 activation in EAE/optic neuritiss
    Haoliang Huang, Linqing Miao, Feisi Liang, Xiaodong Liu, Lin Xu, Xiuyin Teng, Wang Qizhao, William H. Ridder, Kenneth S. Shindler, Yang Sun et al. · 2017 · Cell Death and Disease
  67. ER-associated degradation preserves hematopoietic stem cell quiescence and self-renewal by restricting mTOR activity
    Lu Liu, Ayaka Inoki, Kelly Fan, Fengbiao Mao, Guojun Shi, Xi Jin, Meiling Zhao, Gina M. Ney, Morgan Jones, Shengyi Sun et al. · 2020 · Blood
  68. Biphasic regulation of glutamine consumption by WNT during osteoblast differentiation
    Shen, Leyao, Sharma, Deepika, Yu, Yilin, Long, Fanxin, Karner, Courtney · 2020 · Journal of Cell Science
  69. Curcumin promotes cancer-associated fibroblasts apoptosis via ROS-mediated endoplasmic reticulum stress
    Yanqiong Zeng, Qingdi Du, Zhiwei Zhang, Jing Ma, Le Han, Yuanyuan Wang, Linpu Yang, Ning Tao, Zhihai Qin · 2020 · Archives of Biochemistry and Biophysics
  70. ROS and Endoplasmic Reticulum Stress in Pulmonary Disease
    Xiangning Cui, Yang Zhang, Yingdong Lu, Mi Xiang · 2022 · Frontiers in Pharmacology
  71. Balancing energy and protein homeostasis at ER-mitochondria contact sites
    Amado Carreras‐Sureda, Guido Kroemer, César Cárdenas, Claudio A. Hetz · 2022 · Science Signaling
  72. PERK signaling promotes mitochondrial elongation by remodeling membrane phosphatidic acid
    Valerie Perea, Christian M. Cole, Justine Lebeau, Vivian Dolina, Kelsey R Baron, Aparajita Madhavan, Jeffery W. Kelly, Danielle Ann Grotjahn, R. Luke Wiseman · 2023 · The EMBO Journal
  73. Specific activation of the integrated stress response uncovers regulation of central carbon metabolism and lipid droplet biogenesis
    Katherine Labbè, Lauren LeBon, Bryan King, Ngoc Vu, Emily H. Stoops, Nina Ly, Austin E. Y. T. Lefebvre, Phillip Seitzer, Swathi Krishnan, Jin‐Mi Heo et al. · 2024 · Nature Communications
  74. The integrated stress response in neurodegenerative diseases
    Maria Astrid Bravo-Jimenez, Shivangi Sharma, Soheila Karimi‐Abdolrezaee · 2025 · Molecular Neurodegeneration
  75. Plasticity of the mammalian integrated stress response
    Chien-Wen Chen, David J. Papadopoli, Krzysztof J. Szkop, Bo‐Jhih Guan, Mohammed R. Alzahrani, Jing Wu, Raul Jobava, Mais M. Asraf, Dawid Krokowski, Anastassios Vourekas et al. · 2025 · Nature
  76. ATF4 licenses C/EBPβ activity in human mesenchymal stem cells primed for adipogenesis
    Daniel M. Cohen, Kyoung‐Jae Won, Nha Nguyen, Mitchell A. Lazar, Christopher S. Chen, David J. Steger · 2015 · eLife
  77. GRP78-targeting subtilase cytotoxin sensitizes cancer cells to photodynamic therapy
    Małgorzata Firczuk, Magdalena Gabrysiak, Joanna Barankiewicz, Antoni Domagała, Dominika Nowis, Marek Kujawa, Ewa A. Jankowska-Steifer, Małgorzata Wachowska, Eliza Głodkowska‐Mrówka, Bárbara Korsak et al. · 2013 · Cell Death and Disease
  78. Salubrinal protects against rotenone-induced SH-SY5Y cell death via ATF4-parkin pathway
    Liang Wu, Na Luo, Hong-Rui Zhao, Qing Gao, Jie Lu, Yang Pan, Jingping Shi, You‐Yong Tian, Yingdong Zhang · 2014 · Brain Research
  79. Inhibition of nonsense-mediated RNA decay by ER stress
    Zhelin Li, John K. Vuong, Min Zhang, Cheryl Stork, Sika Zheng · 2016 · RNA
  80. XBP1-KLF9 Axis Acts as a Molecular Rheostat to Control the Transition from Adaptive to Cytotoxic Unfolded Protein Response
    Emily E. Fink, Sudha Moparthy, Archis Bagati, Anna Bianchi, Brittany C. Lipchick, David W. Wolff, Matthew V. Roll, Jianmin Wang, Song Liu, Andrei V. Bakin et al. · 2018 · Cell Reports
  81. Pharmacological Manipulation of Translation as a Therapeutic Target for Chronic Pain
    Muhammad Saad Yousuf, Stephanie I. Shiers, James J. Sahn, Theodore John Price · 2020 · Pharmacological Reviews
  82. Mechanism of Decision Making between Autophagy and Apoptosis Induction upon Endoplasmic Reticulum Stress
    Orsolya Kapuy · 2024 · International Journal of Molecular Sciences
  83. An inhibitor of HIV-1 protease modulates constitutive eIF2α dephosphorylation to trigger a specific integrated stress response
    Aude De Gassart, Bojan Bujisic, Léa Zaffalon, Laurent Arthur Decosterd, Antonia Di Micco, Gianluca Frera, Rémy Tallant, Fabio Martinon · 2015 · Proceedings of the National Academy of Sciences
  84. Tauopathy-Associated PERK Alleles are Functional Hypomorphs that Increase Neuronal Vulnerability to ER Stress
    Shauna H. Yuan, Nobuhiko Hiramatsu, Qing Liu, Xuehan Sun, David Lenh, Priscilla Chan, Karen Chiang, Edward H. Koo, Aimee Kao, Irene Litvan et al. · 2018 · Human Molecular Genetics
  85. Promoter demethylation of the asparagine synthetase gene is required for ATF4-dependent adaptation to asparagine depletion
    Jie Jiang, Sankalp Srivastava, Gretchen L. Seim, Natalya N. Pavlova, Bryan King, Lihua Zou, Chi Zhang, Minghua Zhong, Hui Feng, Reuben Kapur et al. · 2019 · Journal of Biological Chemistry
  86. Hexokinase domain-containing protein-1 in metabolic diseases and beyond
    Joseph Louis Zapater, Kristen Lednovich, Md. Wasim Khan, Carolina M. Pusec, Brian Thomas Layden · 2021 · Trends in Endocrinology and Metabolism
  87. Tumor progression and the different faces of the PERK kinase
    Dariusz Pytel, Ireneusz Majsterek, John Alan Diehl · 2015 · Oncogene
  88. The endoplasmic reticulum and unfolded protein response in the control of mammalian recombinant protein production
    Hirra Hussain, Rodrigo Maldonado‐Agurto, Alan James Dickson · 2014 · Biotechnology Letters
  89. Regulation of PERK–eIF2α signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes
    Minqing Jiang, Lei Liu, Xuelian He, Haibo Wang, Wensheng Lin, Huimin Wang, Sung Ok Yoon, Teresa L. Wood, Qing Richard Lu · 2016 · Nature Communications
  90. Sodium Channel Subunit SCNN1B Suppresses Gastric Cancer Growth and Metastasis via GRP78 Degradation
    Yun Qian, Chi Chun Wong, Jiaying Xu, Huarong Chen, Yanquan Zhang, Wei Kang, Hua Wang, Li Zhang, Weilin Li, Eagle SH Chu et al. · 2017 · Cancer Research
  91. Upregulation of tryptophanyl-tRNA synthethase adapts human cancer cells to nutritional stress caused by tryptophan degradation
    Isabell Adam, Dyah Laksmi Dewi, Joram Mooiweer, Ahmed Sadik, Soumya R. Mohapatra, Bianca Berdel, Melanie Keil, Jana K. Sonner, Kathrin Thedieck, Adam J. Rose et al. · 2018 · OncoImmunology
  92. Unraveling the Molecular Nexus between GPCRs, ERS, and EMT
    Niti Kumari, Somrudee Reabroi, Brian J. North · 2021 · Mediators of Inflammation
  93. Trib3 Is Elevated in Parkinson's Disease and Mediates Death in Parkinson's Disease Models
    Pascaline Aimé, Xiaotian Sun, Neela Zareen, Apeksha Rao, Z. Berman, Laura A. Volpicelli‐Daley, Paulette Bernd, John F. Crary, O. A. Levy, Lloyd A. Greene · 2015 · Journal of Neuroscience
  94. The Pathogenic Role of Persistent Milk Signaling in mTORC1- and Milk- MicroRNA-Driven Type 2 Diabetes Mellitus
    Bodo Clemens Melnik · 2015 · Current Diabetes Reviews
  95. C/EBP-Homologous Protein (CHOP) in Vascular Smooth Muscle Cells Regulates Their Proliferation in Aortic Explants and Atherosclerotic Lesions
    Alex‐Xianghua Zhou, Xiaobo Wang, Chyuan Sheng Lin, Jaeseok Han, Jing Yong, Marissa J. Nadolski, Jan Borén, Randal J. Kaufman, Ira A. Tabas · 2015 · Circulation Research
  96. A Homeostatic Shift Facilitates Endoplasmic Reticulum Proteostasis through Transcriptional Integration of Proteostatic Stress Response Pathways
    Liam Baird, Tadayuki Tsujita, Eri H. Kobayashi, Ryo Funayama, Takeshi Nagashima, Keiko Nakayama, Masayuki P. Yamamoto · 2016 · Molecular and Cellular Biology
  97. Ilamycin E, a natural product of marine actinomycete, inhibits triple-negative breast cancer partially through ER stress-CHOP-Bcl-2
    Wenhui Zhou, Huan Fang, Wu Qiuju, Xinye Wang, Rong Liu, Fubin Li, Ji Xiao, Lin Yuan, Zhongmei Zhou, Junying Ma et al. · 2019 · International Journal of Biological Sciences
  98. Drosophila as a model for unfolded protein response research
    Hyung Don Ryoo · 2015 · BMB Reports
  99. A Novel Dual Kinase Function of the RET Proto-oncogene Negatively Regulates Activating Transcription Factor 4-mediated Apoptosis
    Rozita Bagheri‐Yarmand, Krishna Murari Sinha, Anupama E. Gururaj, Zamal Ahmed, Yasmeen Q. Rizvi, Su‐Chen Huang, John Edward Ladbury, Oliver Bögler, Michelle D. Williams, Gilbert J. Cote et al. · 2015 · Journal of Biological Chemistry
  100. Celastrol induces unfolded protein response-dependent cell death in head and neck cancer
    Andrew M. Fribley, Justin Robert Miller, Amy L. Brownell, Danielle M. Garshott, Qinghua Zeng, Tyler E. Reist, Neha Narula, Peter Cai, Yue Xi, Michael U. Callaghan et al. · 2014 · Experimental Cell Research