An integrin β3-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition

Seguin, Laetitia, Kato, Shumei, Franovic, Aleksandra, Camargo, M. Fernanda, Lesperance, Jacqueline, Elliott, Kathryn C., Yebra, Mayra, Mielgo, Ainhoa +12 more·2014·Nature Cell Biology

DOI 10.1038/ncb2953

Cited by (374)

Items 101–200 of 374

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Caiyun Wang, Tao Wang, Dacheng Lv, Ling Li, Jinnan Yue, Hong-Zhuan Chen, Lu Xu · 2019 · Molecular Cancer Therapeutics
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Heidi L. Reesink, Ryan M. Sutton, Carolyn R. Shurer, Ryan P. Peterson, Julie S. Tan, Jin Su, Matthew J. Paszek, Alan J. Nixon · 2017 · Stem Cell Research & Therapy
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Anthony J. Saviola, Patrick D. Burns, Ashis Kumar Mukherjee, Stephen P. Mackessy · 2016 · International Journal of Biological Macromolecules
Novel and Alternative Targets Against Breast Cancer Stemness to Combat Chemoresistance
Sangita Sridharan, Cory M. Howard, Augustus M. C. Tilley, Boopathi Subramaniyan, Amit Kumar Tiwari, Randall J. Ruch, Dayanidhi Raman · 2019 · Frontiers in Oncology
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Wei Wei, Michael T. Lewis · 2015 · Endocrine Related Cancer
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Alyssa D. Schwartz, Lauren E. Barney, Lauren Jansen, Thuy V. Nguyen, Christopher L. Hall, Aaron S. Meyer, Shelly R. Peyton · 2017 · Integrative Biology
A concise review on the current understanding of pancreatic cancer stem cells
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Haibo Cheng, Xiaoyin Ge, Shiqin Zhuo, Yanan Gao, Bo Zhu, Junfeng Zhang, Wenbin Shang, Dakang Xu, Weihong Ge, Liyun Shi · 2018 · Frontiers in Pharmacology
TRAIL-Mediated Apoptosis in Breast Cancer Cells Cultured as 3D Spheroids
Siddarth Chandrasekaran, Jocelyn R. Marshall, James A. Messing, Jong‐Wei Hsu, Michael R. King · 2014 · PLoS ONE
RKIP-Mediated Chemo-Immunosensitization of Resistant Cancer Cells via Disruption of the NF-κB/Snail/YY1/RKIP Resistance-Driver Loop
Benjamin Bonavida · 2014 · Critical Reviews™ in Oncogenesis
Ras Dimer Formation as a New Signaling Mechanism and Potential Cancer Therapeutic Target
Mo Chen, Alec Peters, Tao Huang, Xiaolin Nan · 2015 · Mini-Reviews in Medicinal Chemistry
Integrin alphavbeta3 enhances β-catenin signaling in acute myeloid leukemia harboring Fms-like tyrosine kinase-3 internal tandem duplication mutations: implications for microenvironment influence on sorafenib sensitivity
Hai Yi, Dongfeng Zeng, Zhaohua Shen, Jun Liao, Xiaoguo Wang, Yao Z. Liu, Xi Zhang, Peiyan Kong · 2016 · Oncotarget
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Qi Sun, Jacqueline Lesperance, Hiromi Inoue Wettersten, Elaine Luterstein, Yoko S. DeRose, Alana L. Welm, David A. Cheresh, Jay S. Desgrosellier · 2017 · Journal of Clinical Investigation
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Sunil J. Advani, Maria F. Camargo, Laetitia Seguin, Ainhoa Mielgo, Sudarshan Anand, Angel M. Hicks, Joseph A. Aguilera, Aleksandra Franovic, Sara M. Weis, David A. Cheresh · 2015 · Nature Communications
CD51 correlates with the TGF-beta pathway and is a functional marker for colorectal cancer stem cells
Jing Wang, Bin Zhang, Hao‐Xiang Wu, Junchao Cai, Xin Yuan Sui, Yuni Wang, Haoyang Li, Yuan Qiu, Tong Wang, Zhitao Chen et al. · 2016 · Oncogene
N-Glycosylation of integrin α5 acts as a switch for EGFR-mediated complex formation of integrin α5β1 to α6β4
Qinglei Hang, Tomoya Isaji, Sicong Hou, Ying Zhou, Tomohiko Fukuda, Jianguo Gu · 2016 · Scientific Reports
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Derya Kabacaoğlu, Dietrich Alexander Ruess, Jiaoyu Ai, Hana Algül · 2019 · Cancers
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Ilaria Casari, Justin Andrew Howard, Eunice Eugenia Robless, Marco Falasca · 2021 · Cancer Letters
Non-canonical integrin signaling activates EGFR and RAS-MAPK-ERK signaling in small cell lung cancer
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Shoujie Chai, Xia Xu, Yongfang Wang, You Zhou, Chenchen Zhang, Yiming Yang, Ying Yang, Haiyan Xu, Rongzhen Xu, Kai Wang · 2015 · Oncotarget
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Quanhui Zhang, Junping Yang, Jie Bai, Jianzhuang Ren · 2018 · Cancer Science
Small extracellular vesicles modulated by αVβ3 integrin induce neuroendocrine differentiation in recipient cancer cells
Fabio Quaglia, Shiv Ram Krishn, George Gaby Daaboul, Srawasti Sarker, Raffaella Pippa, Josep M. Domingo Domenech, Gaurav Kumar, Paolo M. Fortina, Peter A. McCue, William Kevin Kelly et al. · 2020 · Journal of Extracellular Vesicles
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Qinglei Hang, Tomoya Isaji, Sicong Hou, Sanghun Im, Tomohiko Fukuda, Jianguo Gu · 2015 · Journal of Biological Chemistry
Quantitative biophysical analysis defines key components modulating recruitment of the GTPase KRAS to the plasma membrane
Bindu Lakshman, Simon A. J. Messing, Eva M. Schmid, Jeffrey D. Clogston, William Gillette, Dominic Esposito, Bailey D. Kessing, Daniel A. Fletcher, Dwight V. Nissley, Frank P. McCormick et al. · 2018 · Journal of Biological Chemistry
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Igor Tvaroška, Stanislav Kozmon, Juraj Kóňa · 2023 · Cells
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Qing Hua Guo, Yizi Jin, Mingxi Lin, Cheng Zeng, Jian Zhang · 2024 · Life Sciences
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Wenjie Wang, Mengyao Wu, Meng Shen, Qiaoming Zhi, Zeyi Liu, FEI-RAN GONG, MIN TAO, Wei Li · 2015 · International Journal of Oncology
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FOXD1 and Gal-3 Form a Positive Regulatory Loop to Regulate Lung Cancer Aggressiveness
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Avβ3 integrin: Pathogenetic role in osteotropic tumors
Luigia Stefania Stucci, Marco Tucci, Anna Maria Passarelli, Franco Silvestris · 2015 · Critical Reviews in Oncology/Hematology
Therapeutic Potential of a Novel αvβ3 Antagonist to Hamper the Aggressiveness of Mesenchymal Triple Negative Breast Cancer Sub-Type
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Bone sialoprotein‐αvβ3 integrin axis promotes breast cancer metastasis to the bone
Li Wang, Lijie Song, Juan Li, Yan Wang, Chuanhong Yang, Xiaomei Kou, Bin Xiao, Wei Zhang, Linhai Li, Shuwen Liu et al. · 2019 · Cancer Science
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Matthew Kyle Hadden, Anubhav Mittal, Jaswinder Singh Samra, Hala Zreiqat, Sumit Sahni, Yogambha Ramaswamy · 2020 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
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Deepak Raj, Alexandra Aicher, Christopher Heeschen · 2015 · Stem Cells
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Recent progress on curcumin-based therapeutics: a patent review (2012-2016). Part I: Curcumin
Rita Maria Concetta Di Martino, Barbara Luppi, Alessandra Bisi, Silvia Gobbi, Angela Rampa, Angela Abruzzo, Federica Belluti · 2016 · Expert Opinion on Therapeutic Patents
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