Foxk proteins repress the initiation of starvation-induced atrophy and autophagy programs

Bowman, Christopher John, Ayer, Donald E., Dynlacht, Brian David·2014·Nature Cell Biology

DOI 10.1038/ncb3062

Cited by (154)

Items 101–154 of 154

Loss of Fam60a, a Sin3a subunit, results in embryonic lethality and is associated with aberrant methylation at a subset of gene promoters
Ryo Nabeshima, Osamu Nishimura, Takako Maeda, Natsumi Shimizu, Takahiro Ide, Kenta Yashiro, Yasuo Sakai, Chikara Meno, Mitsutaka Kadota, Hidetaka Shiratori et al. · 2018 · eLife
Gene expression profiling of skeletal myogenesis in human embryonic stem cells reveals a potential cascade of transcription factors regulating stages of myogenesis, including quiescent/activated satellite cell-like gene expression
Michael Shelton, Morten Ritso, Jun Liu, Daniel O’Neil, Avetik Kocharyan, Michael A. Rudnicki, William L. Stanford, Ilona Sylvia Skerjanc, Alexandre Blais · 2019 · PLoS ONE
The potential of targeting Sin3B and its associated complexes for cancer therapy
David John Cantor, Gregory David · 2017 · Expert Opinion on Therapeutic Targets
FOXK1 regulates malignant progression and radiosensitivity through direct transcriptional activation of CDC25A and CDK4 in esophageal squamous cell carcinoma
Xiaoxu Li, Juntao Lu, Lei Liu, Fei Li, Tongxin Xu, Liying Chen, Zhaoyang Yan, Yan Li, Wei Guo · 2023 · Scientific Reports
MIR663AHG as a competitive endogenous RNA regulating TGF‐β‐induced epithelial proliferation and epithelial–mesenchymal transition in benign prostate hyperplasia
Shiyu Tong, Miao Mo, Xiheng Hu, Longxiang Wu, Minfeng Chen, Cheng Zhao · 2023 · Journal of Biochemical and Molecular Toxicology
Melatonin inhibits HCC progression through regulating the alternative splicing of NEMO
Lu Bai, Siwen Sun, Wenmei Su, Chaoqun Chen, Yuesheng Lv, Jinrui Zhang, Jinyao Zhao, Man Li, Yangfan Qi, Wenjing Zhang et al. · 2022 · Frontiers in Pharmacology
Prognostic Value of the FOXK Family Expression in Patients with Locally Advanced Rectal Cancer Following Neoadjuvant Chemoradiotherapy
Yiyi Zhang, Meifang Xu, Jianhua Chen, Kui Chen, Jinfu Zhuang, Yuanfeng Yang, Xing Liu, Guoxian Guan · 2020 · OncoTargets and Therapy
Forkhead box K1 regulates the malignant behavior of gastric cancer by inhibiting autophagy
Yixuan Wang, Wensheng Qiu, Ning Liu, Libin Sun, Zhao Liu, Shasha Wang, Peng Wang, Shihai Liu, Jing Lv · 2020 · Annals of Translational Medicine
Transcriptome Sequencing Analysis Reveals Dynamic Changes in Major Biological Functions during the Early Development of Clearhead Icefish, Protosalanx chinensis
Xuemei Tang, Shulun Jiang, Henglin Wang, Yanfeng Zhou, Fei Peng, Xizhao Zhang, Yifan Zhou, Shiyue Guo, Yang You · 2022 · Fishes
Epigenomics analysis of miRNA cis-regulatory elements in pig muscle and fat tissues
Mingyang Hu, Renzhuo Kuang, Yaping Guo, Ruixian Ma, Ye Hou, Yueyuan Xu, Xiaolong Qi, Daoyuan Wang, Honghong Zhou, Youcai Xiong et al. · 2022 · Genomics
Suppression of the long non-coding RNA LINC01279 triggers autophagy and apoptosis in lung cancer by regulating FAK and SIN3A
Jiancong Wu, Xiaobi Huang, Xiaofang Li, Honglian Zhou, Xiaorao Chen, Yongyang Chen, Yudong Guo, Jian Hua Huang, Hanqing Huang, Zhong Huang et al. · 2024 · Discover Oncology
FOXK2 transcription factor and its roles in tumorigenesis (Review)
Zhaojun Wang, Xinling Liu, Zhanju Wang, Zhenbo Hu · 2022 · Oncology Letters
Emerging roles of FOXK2 in cancers and metabolic disorders
Xiaoke Xing, Xiangyong Que, Sihao Zheng, Shuxian Wang, Qibin Song, Yi Yao, Pingfeng Zhang · 2024 · Frontiers in Oncology
O-GlcNAcylation of FOXK1 co-opts BAP1 to orchestrate the E2F pathway and promotes oncogenesis
2025
FRET‐Based Sensor Zebrafish Reveal Muscle Cells Do Not Undergo Apoptosis in Starvation or Natural Aging‐Induced Muscle Atrophy
Jia Hao, Renfei Wu, Hongmei Yang, Kathy Qian Luo · 2025 · Advanced Science
Depletion of Foxk transcription factors causes genome-wide transcriptional misregulation and developmental arrest in zebrafish embryos
Fan‐Suo Geng, Elisa de la Calle‐Mustienes, José Luis Gómez-Skármeta, Ryan Lister, Ozren Bogdanović · 2020 · PubMed Central
Autophagy in Cancer: A Metabolic Perspective
Sweta Sikder, Atanu Mondal, Chandrima Das, Tapas Kumar Kundu · 2022 · Sub-cellular biochemistry/Subcellular biochemistry
CangFu Daotan decoction improves polycystic ovarian syndrome by downregulating FOXK1
Chenye Wang, Jia Yu, Caifei Ding, Chun-Yue Chen · 2023 · Gynecological Endocrinology
FoxK1 associated gene regulatory network in hepatic insulin action and its relationship to FoxO1 and insulin receptor mediated transcriptional regulation
P. Allu, M. Cardamone, Antonio S. Gomes, Alessandra Dall'agnese, Carly T. Cederquist, Hui Pan, J. Dreyfuss, S. Enerbäck, C. R. Kahn · 2023 · Molecular Metabolism
O-GlcNAcylation of FOXK1 orchestrates the E2F pathway and promotes oncogenesis
Masclef, Louis, Ahmed, Oumaima, Iannantuono, Nicholas, Gagnon, Jessica, Gushul-Leclaire, Mila, Boulay, Karine, Estavoyer, Benjamin, Echbicheb, Mohamed, Poy, Marty, Ali Boubacar, Kalidou et al. · 2024
A20’s linear ubiquitin–binding motif restrains pathogenic activation of Th17 cells and IL-22–driven enteritis
Christopher Bowman, Dorothea Stibor, Xiaofei Sun, Hiromichi Shimizu, Emily Yamashita, Nika Lenci, Rommel Advincula, Min Cheol Kim, Jessie A. Turnbaugh, Yang Sun et al. · 2025 · Journal of Clinical Investigation
Transcriptional and epigenetic regulation of autophagy: mechanisms, disease relevance and therapeutic opportunities
Jieun Seo, Seo‐Young Park, Dong Chul Lee, Wonbeak Yoo, Yong Ryoul Yang, Hwi Won Seo, Jong Lyul Park, Jae‐Yeol Joo, Kyung Chan Park, Sangwon Byun · 2026 · Signal Transduction and Targeted Therapy
Danshensu methyl ester enhances autophagy to attenuate pulmonary fibrosis by targeting lncIAPF–HuR complex
Qi Zhu, Jing Wang, Yunxia Ji, Jianlin Luan, Dayong Yue, Weili Liu, Hongbo Li, Jinjin Zhang, Guiwu Qu, Changjun Lv et al. · 2022 · Frontiers in Pharmacology
Foxk2 Enhances Adipogenic Differentiation by Relying on the Transcriptional Activation of Peroxisome Proliferator‐Activated Receptor Gamma
Shan Zhang, Yanru You, Ran Li, Mingcong Li, Yachong Li, Hairui Yuan, Jie Zhou, Ruonan Zhen, Ying Liu, Baoli Wang et al. · 2025 · Journal of Cellular and Molecular Medicine
Foxk1 stimulates adipogenic differentiation via a peroxisome proliferator‐activated receptor gamma 2‐dependent mechanism
Shan Zhang, Yanru You, Yachong Li, Hairui Yuan, Jie Zhou, Lijie Tian, Ying Liu, Baoli Wang, Endong Zhu · 2023 · The FASEB Journal
FOXK1 promotes hormonally responsive breast carcinogenesis by suppressing apoptosis
Minghui Zhao, Tingyao Ma, Zhaohan Zhang, Yu Wang, Xilin Wang, Wenjuan Wang, Xiaohong Chen, Ran Gao, Lin Shan · 2024 · Animal Models and Experimental Medicine
The role of FOXK2 – FBXO32 in breast cancer tumorigenesis: Insights into ribosome‐associated pathways
Fuben Liao, Jinjin Zhu, Junju He, Zheming Liu, Yi Yao, Qibin Song · 2024 · Thoracic Cancer
Unveiling roles of NGLY1 in cellular homeostasis and related diseases
Chenxi Zhan, Xuye Zhao, Yaoxin Wei, Renqiang Yang, Nianlong Yan · 2025 · Cellular Signalling
Antiviral Activity of Eugenol Against Largemouth Bass Ranavirus Through Regulation of Autophagy and Apoptosis In Vitro and In Vivo
Yewen Wang, Lifang Cao, Leshan Ruan, Xingyu Chen, Chunhui Song, Shina Wei, Yunchang Xie · 2025 · Microorganisms
AMPK signaling in autophagy induction
Bishnu Prasad Behera, Sujit K. Bhutia · 2023 · Elsevier eBooks
FoxK1 and FoxK2 cooperate with ORF45 to promote late lytic replication of Kaposi’s sarcoma-associated herpesvirus
Qingyang Chen, Xiaojuan Li, Li Quan, Rihong Zhou, Xiangpeng Liu, Lu Cheng, Ronit Sarid, Ersheng Kuang · 2024 · Journal of Virology
Sex-specific skeletal muscle gene expression responses to exercise reveal novel direct mediators of insulin sensitivity change
Sisi Ma, Monica J. Hubal, Matthew C. Morris, Leanna M. Ross, Kim M. Huffman, Christopher G. Vann, Nadia Moore, Elizabeth R. Hauser, Akshay Bareja, Rong Jiang et al. · 2025 · NAR Molecular Medicine
Ambroxol induces myeloma cell death by inhibiting autophagy
Yutaka Hattori, Hiromu Sugiyama, Yamato Miyashita, Shinsuke Shibata, Taiga Okaue, Yoshinao Matsumoto, Taketo Yamada, Tomofumi Yamamoto, Takashi Yamaguchi, Kohei Yamazaki et al. · 2025 · Blood Neoplasia
FOXK2 in skeletal muscle development: a new pathogenic gene for congenital myopathy with ptosis
Peixuan Wu, Nan Song, Yang Xiang, Zhe Tao, Bing Mao, Ruochen Guo, Xin Wang, Dan Wu, Zhenzhen Zhang, Xin Chen et al. · 2025 · EMBO Molecular Medicine
Lysine-rich rice enhanced muscle growth and development in young rats
Pui Kit Suen, Lizhen Zheng, Qingqing Yang, Wan Sheung Mak, Wan Yu Pak, Kyoung Hoon Mo, Man-ling Chan, Qiaoquan Liu, Ling Qin, Samuel S. M. Sun · 2025 · European Journal of Nutrition
THE RETURN OF THE NUCLEUS - EPIGENETIC REGULATION OF AUTOPHAGY
Jens Füllgrabe · 2015 · Figshare
Avaliação da expressão de retrovírus endógenos humanos em pacientes com neuroblastoma.
Danielle Ferreira e Silva · 2016
Genome-wide search for quantitative trait loci (QTL) and genes for increased growth and improved fatty acid content in salt tolerant tilapia (oreochromis spp.)
Grace Lin · 2018
Suppression of the Long Non-Coding RNA LINC01279 Triggers Autophagy and Apoptosis in Lung Cancer by Regulating FAK and SIN3A
Wenmei Su, Jiancong Wu, Xiaobi Huang, Xiaofang Li, Honglian Zhou, Xiaorao Chen, Yongyang Chen, Jian Hua Huang, Hanqing Huang, Zhong Huang et al. · 2022 · Research Square
Research Progress of FOXK1 in Malignant Tumors
娇马 · 2023 · Advances in Clinical Medicine
Targeting FOXK2 in triple-negative breast cancer: Role of the P53/MCAS1/miR-211–5p regulatory axis
Zankai Wu, Yanting Zhang, Dandan Xiang, Tian Li, Yiping Gong, Qibin Song, Jin Hu · 2025 · Functional & Integrative Genomics
FOXK2 gene expression in cancer: Potential regulatory mechanisms and clinical implications
Renata Ivo Vasconcelos, Luciana da Torre Carneiro, Raquel Ciuvalschi Maia, Thaís Hancio, Gabriela Nestal de Moraes · 2025 · Genes & Diseases
Dual mechanism of autophagy gene repression by PHF23 and therapeutic potential of its inhibition in protein aggregation disorders
Seon Ah Choi, Jaebeom Kim, Young Suk Yu, Jaemin Kim, Se In Kim, Hamin Bae, Junhee Kwon, Keun Il Kim, Sung Hee Baek · 2025 · Nucleic Acids Research
A C-terminal cytoplasmic retention motif and nuclear localization signal regulates nuclear import of TP53INP2
Birendra Kumar Shrestha, Eva Sjøttem, Hallvard Lauritz Olsvik, Isaac Odonkor, Aud Øvervatn, Hanne Britt Brenne, Jack‐Ansgar Bruun, Trond Lamark, Terje Johansen · 2024 · Journal of Cell Science
Additional file 1 of Prediction of enhancer–promoter interactions using the cross-cell type information and domain adversarial neural network
Fang Jing, ShaoWu Zhang, Zhang, Shihua · 2020 · Figshare
Counteracting FOX proteins epigenetically control the herpesvirus lytic-latent balance
Yuhang Xiang, Xiyuan Yang, Juncheng Zhang, Fujun Hou, Yue Cheng Deng, Hui Fu, Hyung Suk Oh, Qiongyan Wang, Siyu Chen, Zeyu Sun et al. · 2026 · Nature Communications
pCancer and FOXK2 (Forkhead Box K2): Oncogenic and Tumor-Suppressive Roles of FOXK2 in Cancer
Şeyda Akın, İbrahim Ozturk, Ceylan Hepokur · 2026 · Biochemical Genetics
Identification and Validation of FOXK1-Related Biomarkers in Diabetic Retinopathy
Xin Li, He Long, Shaomin Peng · 2026 · International Journal of General Medicine
Biochemical characterization of mTORC1 regulation by glutamine metabolism
Clément Bodineau · 2020 · theses.fr (ABES)
Rôles de FOXO3 dans la réponse cellulaire au stress et la neurodégénérescence au cours de la maladie Parkinson
Baptiste Texier · 2024 · theses.fr (ABES)
Therapeutic targeting of the PRMT6/FOXK1 axis restores lipid homeostasis and ameliorates hepatic steatosis and steatohepatitis in mice
Yang Sun, Tao Chen, Lei Zhang, Jinlin Duan, Junyan Xue, Wentao Huang, Jian-Zhong Di, Yonglong Zhang · 2026 · Acta Pharmaceutica Sinica B
Lineage master regulator and cancer-selective partner transcription factors rewire 3D genome topology for tumor-specific gene control
N. Jung, V. Lopez-Pajares, L. Donohue, M. Guo, Suhas Srinivasan, Z. Siprashvili, P. Khavari · 2026 · Science Advances
AKT Phosphorylation of FOXK2 at Ser398 Impacts Breast Cancer Cell Growth and Viability
Luis A. Carneiro, J. M. R. C. Nunes, Giuliana De Gregoriis, Bruna dos Santos Mendonça, Wallace Martins de Araújo, Raquel Ciuvalschi Maia, Eric W.‐F. Lam, Renato Sampaio Carvalho, Marcelo Alex Carvalho, Andrew D Sharrocks et al. · 2026 · The FASEB Journal
Stress hyperglycemia impairs FOXK2-dependent macrophage cardiac repair after myocardial infarction
Huizhen Lv, Zening Liu, Suli Feng, Wennan Liu, Yifan Guo, Kaiwen Bao, Xilin Shen, Yongle Li, Xin Zhou, Ding Ai et al. · 2026 · Cell Reports