Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis

Cited by (444)

Items 101–200 of 444

  1. Liver Tropism in Cancer: The Hepatic Metastatic Niche
    Ainhoa Mielgo, Michael C. Schmid · 2019 · Cold Spring Harbor Perspectives in Medicine
  2. The reciprocal regulation between host tissue and immune cells in pancreatic ductal adenocarcinoma: new insights and therapeutic implications
    Xiaomeng Liu, Jin Xu, Bo Zhang, Jiang Liu, Chen Liang, Qingcai Meng, Jie Hua, Xianjun Yu, Si Shi · 2019 · Molecular Cancer
  3. Progranulin mediates immune evasion of pancreatic ductal adenocarcinoma through regulation of MHCI expression
    Phyllis F. Cheung, Jiajin Yang, Rui Fang, Arianna Borgers, Kirsten Krengel, Anne Stoffel, Kristina Althoff, Chi Wai Yip, Elaine Hon-Lam Siu, Linda W.C. Ng et al. · 2022 · Nature Communications
  4. Single cell deciphering of progression trajectories of the tumor ecosystem in head and neck cancer
    Z. L. Liu, Xiangyan Meng, Rujuan Bao, M. Y. Shen, J. J. Sun, W. D. Chen, Fei‐Fei Liu, Yue He · 2024 · Nature Communications
  5. Pro-tumorigenic functions of macrophages at the primary, invasive and metastatic tumor site
    Elaheh Nasrollahzadeh, Sepideh Razi, Mahsa Keshavarz‐Fathi, Massimiliano Mazzone, Nima Rezaei · 2020 · Cancer Immunology Immunotherapy
  6. Macrophages direct cancer cells through a LOXL2-mediated metastatic cascade in pancreatic ductal adenocarcinoma
    Marta Alonso‐Nocelo, Laura Ruíz-Cañas, Patricia Sancho, Kıvanç Görgülü, Sonia Alcalá, Coral Pedrero, Mireia Vallespinós, Juan Carlos López-Gil, Marina Ochando, Elena García-García et al. · 2022 · Gut
  7. The multifaceted role of periostin in priming the tumor microenvironments for tumor progression
    Dan Cui, Zhengjie Huang, Yingfu Liu, Gaoliang Ouyang · 2017 · Cellular and Molecular Life Sciences
  8. The fibrotic and immune microenvironments as targetable drivers of metastasis
    Luke Boulter, Esme Bullock, Zeanap Mabruk, Valerie G. Brunton · 2020 · British Journal of Cancer
  9. Liver Immune Microenvironment and Metastasis from Colorectal Cancer-Pathogenesis and Therapeutic Perspectives
    Xuezhen Zeng, Simon E. Ward, Jingying Zhou, Alfred S.L. Cheng · 2021 · Cancers
  10. Blockade of insulin-like growth factors increases efficacy of paclitaxel in metastatic breast cancer
    Lucy Ireland, Almudena Santos, Fiona Campbell, Carlos R. Figueiredo, Dean E. Hammond, Lesley G. Ellies, Ulrike Weyer-Czernilofsky, Thomas Bogenrieder, Michael C. Schmid, Ainhoa Mielgo · 2018 · Oncogene
  11. Microglial Progranulin: Involvement in Alzheimer’s Disease and Neurodegenerative Diseases
    Mendsaikhan, Anarmaa, Tooyama, Ikuo, Walker, Douglas G. · 2019 · Cells
  12. Innate and acquired immune surveillance in the postdissemination phase of metastasis
    Hugo González Velozo, Isabella Robles, Zena Werb · 2017 · FEBS Journal
  13. Targeting Tumor-Associated Macrophages to Increase the Efficacy of Immune Checkpoint Inhibitors: A Glimpse into Novel Therapeutic Approaches for Metastatic Melanoma
    Claudia Ceci, Maria Grazia Atzori, Pedro Miguel Lacal, Grazia Graziani · 2020 · Cancers
  14. Characteristics of pre-metastatic niche: the landscape of molecular and cellular pathways
    Hao Wang, Junjie Pan, Livnat Barsky, Jule Caroline Jacob, Yan Zheng, Chao Gao, Shun Wang, Wenwei Zhu, Haoting Sun, Lu Lu et al. · 2021 · Molecular Biomedicine
  15. Liver sinusoidal endothelial cell ICAM-1 mediated tumor/endothelial crosstalk drives the development of liver metastasis by initiating inflammatory and angiogenic responses
    Aitor Benedicto, Alba Herrero, Irene Romayor, Joana Márquez, Bård H. Smedsrød, Elvira Olaso, Beatriz Arteta · 2019 · Scientific Reports
  16. Macrophage-fibroblast JAK/STAT dependent crosstalk promotes liver metastatic outgrowth in pancreatic cancer
    Meirion Raymant, Yuliana Astuti, Laura Álvaro‐Espinosa, Daniel M. Green, Valeria Quaranta, Gaia Bellomo, Mark A. Glenn, Vatshala Chandran-Gorner, Daniel H. Palmer, Christopher Michael Halloran et al. · 2024 · Nature Communications
  17. Macrophage diversity in cancer dissemination and metastasis
    Alberto Mantovani, Federica Marchesi, Diletta Di Mitri, Cecília Garlanda · 2024 · Cellular and Molecular Immunology
  18. Bone Marrow Mesenchymal Stromal Cell-Derived Periostin Promotes B-ALL Progression by Modulating CCL2 in Leukemia Cells
    Zhenling Ma, Xueli Zhao, Mingjiao Deng, Zhengjie Huang, Jing Wang, Yi Wu, Dan Cui, Yingfu Liu, Rushi Liu, Gaoliang Ouyang · 2019 · Cell Reports
  19. Bifidobacterium adolescentis orchestrates CD143 + cancer‐associated fibroblasts to suppress colorectal tumorigenesis by Wnt signaling‐regulated GAS1
    Shujie Chen, Lina Fan, Yifeng Lin, Yadong Qi, Chaochao Xu, Qiwei Ge, Ying Zhang, Qiwen Wang, Dingjiacheng Jia, Lan Wang et al. · 2023 · 癌症:英文版
  20. Tumor-associated macrophage-secreted 14-3-3ζ signals via AXL to promote pancreatic cancer chemoresistance
    Gabriele D’Errico, Marta Alonso‐Nocelo, Mireia Vallespinós, Patrick Christian Hermann, Sonia Alcalá, Coral Pedrero, Laura Martín-Hijano, Sandra Valle, Julie Earl, Chiara Cassiano et al. · 2019 · Oncogene
  21. Pericytes in the Premetastatic Niche
    Ana E. Paiva, Luiza Lousado, Daniel A. P. Guerra, Patrick Orestes de Azevedo, Isadora F. G. Sena, Julia P. Andreotti, Gabryella S. P. Santos, Ricardo Gonçalves, Akiva Mintz, Alexander Birbrair · 2018 · Cancer Research
  22. Metastasis as a systemic disease: molecular insights and clinical implications
    Maša Alečković, Sandra S. McAllister, Kornélia Polyák · 2019 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  23. Tissue-Resident and Recruited Macrophages in Primary Tumor and Metastatic Microenvironments: Potential Targets in Cancer Therapy
    Tiziana Cotechini, Aline Atallah, Arielle Grossman · 2021 · Cells
  24. Targeting type I collagen for cancer treatment
    Run Shi, Zhe Zhang, An-Kai Zhu, Xingxing Xiong, Jie Zhang, Jiang Xu, Man‐Sun Sy, Chaoyang Li · 2022 · International Journal of Cancer
  25. Macrophages and fibroblasts as regulators of the immune response in pancreatic cancer
    Mojdeh Shakiba, David Arthur Tuveson · 2025 · Nature Immunology
  26. Bone-marrow-derived cell-released extracellular vesicle miR-92a regulates hepatic pre-metastatic niche in lung cancer
    Ya‐Ling Hsu, Ming‐Shyan Huang, Jen‐Yu Hung, Wei‐An Chang, Ying‐Ming Tsai, Yi‐Chung Pan, Yi-Shiuan Lin, Hung‐Pei Tsai, Po‐Lin Kuo · 2019 · Oncogene
  27. Glufosinate constrains synchronous and metachronous metastasis by promoting anti‐tumor macrophages
    Alessio Menga, Marina Serra, Simona Todisco, Carla Riera‐Domingo, Ummi Ammarah, Manuel Ehling, Erika Mariana Palmieri, Maria Antonietta Di Noia, Rosanna Gissi, Maria Favia et al. · 2020 · EMBO Molecular Medicine
  28. Friend or Foe? Recent Strategies to Target Myeloid Cells in Cancer
    M. Chaib, S. Chauhan, Liza Makowski · 2020 · Frontiers in Cell and Developmental Biology
  29. The unique immune microenvironment of liver metastases: Challenges and opportunities
    Aaron Ciner, Keaton Ian Jones, Ruth J. Muschel, Pnina Brodt · 2020 · Seminars in Cancer Biology
  30. Chimeric Antigen Receptor beyond CAR-T Cells
    Vicky Mengfei Qin, Criselle D’Souza, Paul Joseph Neeson, Joe Jiang Zhu · 2021 · Cancers
  31. Molecular Events in the Natural History of Pancreatic Cancer
    Leslie E. Oldfield, Ashton Anthony Connor, Steve Gallinger · 2017 · Trends in cancer
  32. Periostin‐ and podoplanin‐positive cancer‐associated fibroblast subtypes cooperate to shape the inflamed tumor microenvironment in aggressive pancreatic adenocarcinoma
    Cindy Neuzillet, Rémy Nicolle, Jérôme Raffenne, Annemilaï Tijeras‐Raballand, Alexia Brunel, Lucile Astorgues‐Xerri, Sophie Vacher, Floriane Arbaretaz, Marjorie Fanjul, Marc Hilmi et al. · 2022 · The Journal of Pathology
  33. Single-cell RNA-sequencing atlas reveals an FABP1-dependent immunosuppressive environment in hepatocellular carcinoma
    Weiwei Tang, Guangshun Sun, Gu‐Wei Ji, Tingting Feng, Qian Zhang, Hengsong Cao, Wenhao Wu, Xiaoyi Zhang, Chuan Liu, Han-Yuan Liu et al. · 2023 · Journal for ImmunoTherapy of Cancer
  34. Cancer-Associated Fibroblasts: Accomplices in the Tumor Immune Evasion
    Marc Hilmi, Rémy Nicolle, Corinne Bousquet, Cindy Neuzillet · 2020 · Cancers
  35. Molecular profile of metastasis, cell plasticity and EMT in pancreatic cancer: a pre-clinical connection to aggressiveness and drug resistance
    Zhenli Guo, Milad Ashrafizadeh, Wei Zhang, Rongjun Zou, Gautam Sethi, Xianbin Zhang · 2023 · Cancer and Metastasis Reviews
  36. The role of hepatic macrophages in liver metastasis
    Jiri Keirsse, Helena Van Damme, Xenia Geeraerts, Alain Beschin, Geert Raes, Jo A. Van Ginderachter · 2018 · Cellular Immunology
  37. Metastasis-associated fibroblasts: an emerging target for metastatic cancer
    Zimu Wang, Jiaxin Liu, Hairong Huang, Mingxiang Ye, Xinying Li, Ranpu Wu, Hongbing Liu, Yong Song · 2021 · Biomarker Research
  38. Periostin blockade overcomes chemoresistance via restricting the expansion of mesenchymal tumor subpopulations in breast cancer
    Youya Nakazawa, Yoshiaki Taniyama, Fumihiro Sanada, Ryuichi Morishita, Shoji Nakamori, Koji Morimoto, Kay T. Yeung, Jing Yang · 2018 · Scientific Reports
  39. High baseline tumor burden‐associated macrophages promote an immunosuppressive microenvironment and reduce the efficacy of immune checkpoint inhibitors through the IGFBP2‐STAT3‐PD‐L1 pathway
    Zhaowei Wen, Huiying Sun, Zhihua Zhang, Yannan Zheng, Siting Zheng, Jianping Bin, Yulin Liao, Min Shi, Rui Zhou, Wangjun Liao · 2023 · 癌症:英文版
  40. Interactions among myeloid regulatory cells in cancer
    Viktor Umansky, Gosse J. Adema, Jarosław Baran, Sven Brandau, Jo A. Van Ginderachter, Xiaoying Hu, Jadwiga Jabłońska, Slavko B. Mojsilović, Helen Α. Papadaki, Yago Pico de Coaña et al. · 2018 · Cancer Immunology Immunotherapy
  41. Myeloid Cell Mediated Immune Suppression in Pancreatic Cancer
    Samantha B. Kemp, Marina Pasca di Magliano, Howard C. Crawford · 2021 · Cellular and Molecular Gastroenterology and Hepatology
  42. Locally sourced: site-specific immune barriers to metastasis
    Ana Luísa Correia · 2023 · Nature reviews. Immunology
  43. Innovative Approaches in the Battle Against Cancer Recurrence: Novel Strategies to Combat Dormant Disseminated Tumor Cells
    Scott J. Sauer, Damon R. Reed, Michael A. Ihnat, Robert E. Hurst, David Warshawsky, Dalit Barkan · 2021 · Frontiers in Oncology
  44. Syk Inhibition Reprograms Tumor-Associated Macrophages and Overcomes Gemcitabine-Induced Immunosuppression in Pancreatic Ductal Adenocarcinoma
    Deepak Rohila, In Hwan Park, Timothy V. Pham, Jonathan Weitz, Tatiana Hurtado de Mendoza, Suresh Madheswaran, Mehreen Ishfaq, Cooper Beaman, Elisabette Tapia, Siming Sun et al. · 2023 · Cancer Research
  45. Single-cell analysis reveals the COL11A1+ fibroblasts are cancer-specific fibroblasts that promote tumor progression
    Jiayu Zhang, Shiqi Lu, Tong Lü, Donghui Han, Keying Zhang, Lunbiao Gan, Xinjie Wu, Yu Li, Xiaolong Zhao, Zhengxuan Li et al. · 2023 · Frontiers in Pharmacology
  46. Loss of NDRG2 in liver microenvironment inhibits cancer liver metastasis by regulating tumor associate macrophages polarization
    Mengyang Li, Xiaofeng Lai, Ying Zhao, Yuan Zhang, Minghui Li, Danxiu Li, Jing Kong, Yong Zhang, Pengyu Jing, Huichen Li et al. · 2018 · Cell Death and Disease
  47. Combined blockade of TGf-β1 and GM-CSF improves chemotherapeutic effects for pancreatic cancer by modulating tumor microenvironment
    Qiaofei Liu, Huanwen Wu, Yuan Li, Ronghua Zhang, Jorg H. Kleeff, Xiang Zhang, Ming Cui, Jingkai Liu, Tong Li, Junyi Gao et al. · 2020 · Cancer Immunology Immunotherapy
  48. Incidence and prognosis of liver metastasis at diagnosis: a pan-cancer population-based study.
    Shuncong Wang, Yuanbo Feng, Johannes V. Swinnen, Raymond Oyen, Yue Li, Yicheng Ni · 2020 · PubMed Central
  49. TIMP1 expression underlies sex disparity in liver metastasis and survival in pancreatic cancer
    Chris D. Hermann, Benjamin Schoeps, Celina Eckfeld, Enkhtsetseg Munkhbaatar, Lukas Kniep, Olga Prokopchuk, Nils Wirges, Katja Steiger, Daniel Häußler, Percy Alexander Knolle et al. · 2021 · The Journal of Experimental Medicine
  50. Macrophage and Neutrophil Interactions in the Pancreatic Tumor Microenvironment Drive the Pathogenesis of Pancreatic Cancer
    Hillary G. Pratt, Kayla J. Steinberger, Nicole E. Mihalik, Sascha Ott, Thomas Whalley, Barbara Szomolay, Brian A. Boone, Timothy D. Eubank · 2021 · Cancers
  51. Emerging Role of Cancer-Associated Fibroblasts in Progression and Treatment of Hepatocellular Carcinoma
    H. Akkız · 2023 · International Journal of Molecular Sciences
  52. RETRACTED ARTICLE: Knockdown of FOXO3a induces epithelial-mesenchymal transition and promotes metastasis of pancreatic ductal adenocarcinoma by activation of the β-catenin/TCF4 pathway through SPRY2
    Jun Li, Rumeng Yang, Yuting Dong, Manyao Chen, Yu Wang, Guoping Wang · 2019 · Journal of Experimental & Clinical Cancer Research · Retracted
  53. Immune Cell Modulation of the Extracellular Matrix Contributes to the Pathogenesis of Pancreatic Cancer
    Ramiz S. Ahmad, Timothy D. Eubank, Sławomir Łukomski, Brian A. Boone · 2021 · Biomolecules
  54. Gastric cancer-derived LBP promotes liver metastasis by driving intrahepatic fibrotic pre-metastatic niche formation
    Li Xie, Shengkui Qiu, Lu Chen, Chao Gu, Jihuan Wang, Jialun Lv, Lang Fang, Zetian Chen, Ying Li, Tianlu Jiang et al. · 2023 · Journal of Experimental & Clinical Cancer Research
  55. Cancer-induced systemic pre-conditioning of distant organs: building a niche for metastatic cells
    Nicolas Rabas, Rute M. M. Ferreira, Stefania Di Blasio, Ilaria Malanchi · 2024 · Nature reviews. Cancer
  56. The role of the immune tumor microenvironment in shaping metastatic dissemination, dormancy, and outgrowth
    Garis Grant, Christina M. Ferrer · 2025 · Trends in Cell Biology
  57. Blockade of Stromal Gas6 Alters Cancer Cell Plasticity, Activates NK Cells, and Inhibits Pancreatic Cancer Metastasis
    Lucy Ireland, Teifion Luckett, Michael C. Schmid, Ainhoa Mielgo · 2020 · Frontiers in Immunology
  58. Exosome-derived tRNA fragments tRF-GluCTC-0005 promotes pancreatic cancer liver metastasis by activating hepatic stellate cells
    Wei Chen, Peng Wang, Ronghua Wang, Shuya Bai, Mengdie Cao, Si Xiong, Yanling Li, Yilei Yang, Jingwen Liang, Luyao Liu et al. · 2024 · Cell Death and Disease
  59. PGRN−/− TAMs-derived exosomes inhibit breast cancer cell invasion and migration and its mechanism exploration
    Shujun Yue, Xiangsen Ye, Ting Zhou, Delu Gan, Husun Qian, Wenli Fang, Mengli Yao, Dian Zhang, He Shi, Tingmei Chen · 2020 · Life Sciences
  60. Bone metastasis is associated with acquisition of mesenchymal phenotype and immune suppression in a model of spontaneous breast cancer metastasis
    Lea Monteran, Nour Ershaid, Idan Sabah, Ibrahim Fahoum, Yael Zait, Ophir Shani, Noam Cohen, Anat Eldar‐Boock, Ronit Satchi‐Fainaro, Neta Erez · 2020 · Scientific Reports
  61. Kupffer cells prevent pancreatic ductal adenocarcinoma metastasis to the liver in mice
    Stacy K. Thomas, Max Miller Wattenberg, Shaanti Choi-Bose, Mark T. Uhlik, Ben Harrison, Heather Coho, Christopher R. Cassella, Meredith L. Stone, Dhruv G. Patel, Kelly Markowitz et al. · 2023 · Nature Communications
  62. Cancer Cell Derived Small Extracellular Vesicles Contribute to Recipient Cell Metastasis Through Promoting HGF/c-Met Pathway*
    Zhi Qiao, Yan Zhang, Maolin Ge, Sha Liu, Xiaoteng Jiang, Zhi Shang, Han Liu, Chengxi Cao, Hua Xiao · 2019 · Molecular & Cellular Proteomics
  63. Macrophages and tumor-associated macrophages in the senescent microenvironment: From immunosuppressive TME to targeted tumor therapy
    Ming Du, Lu Sun, J.J. Guo, Huina Lv · 2024 · Pharmacological Research
  64. Single-cell RNA transcriptome reveals the intra-tumoral heterogeneity and regulators underlying tumor progression in metastatic pancreatic ductal adenocarcinoma
    Qianhui Xu, Shaohuai Chen, Yuanbo Hu, Wen Huang · 2021 · Cell Death Discovery
  65. Splenectomy improves liver fibrosis via tumor necrosis factor superfamily 14 (LIGHT) through the JNK/TGF-β1 signaling pathway
    Qing-shan Liang, Jiangang Xie, ChaoPing Yu, Zhusheng Feng, Jingchang Ma, Yuan Zhang, Dong Wang, Jianguo Lu, Ran Zhuang, Jikai Yin · 2021 · Experimental & Molecular Medicine
  66. An Aggrephagy-Related LncRNA Signature for the Prognosis of Pancreatic Adenocarcinoma
    Xueyuan Huang, Hao Chi, Siqi Gou, Xiyuan Guo, Lin Li, Gaoge Peng, Jinhao Zhang, Jiayu Xu, Siji Nian, Qing Yuan · 2023 · Genes
  67. Curcumin reduces Ly6Chi monocyte infiltration to protect against liver fibrosis by inhibiting Kupffer cells activation to reduce chemokines secretion
    Xiang‐An Zhao, Guangmei Chen, Yong Liu, Yuxin Chen, Hongyan Wu, Yali Xiong, Guiyang Wang, Bei Jia, Yang Li, Juan Xia et al. · 2018 · Biomedicine & Pharmacotherapy
  68. Phenylboronic acid modified nanoparticles simultaneously target pancreatic cancer and its metastasis and alleviate immunosuppression
    Zhengze Lu, Yang Long, Yashi Wang, Xuhui Wang, Chunyu Xia, Man Li, Zhirong Zhang, Qin He · 2021 · European Journal of Pharmaceutics and Biopharmaceutics
  69. The Immunomechanical Checkpoint PYK2 Governs Monocyte-to-Macrophage Differentiation in Pancreatic Cancer
    Wenyan Xie, Xin Yu, Qingxin Yang, Nengwen Ke, Ping Wang, Hao Kong, Xiangji Wu, Panpan Ma, Lang Chen, Jie Yang et al. · 2025 · Cancer Discovery
  70. Impact of immune cells on the hallmarks of cancer: A literature review
    Alexandra C. Costa, Joana Santos, Rui M. Gil da Costa, Rui Medeiros · 2021 · Critical Reviews in Oncology/Hematology
  71. The Heterogeneity of the Tumor Microenvironment as Essential Determinant of Development, Progression and Therapy Response of Pancreatic Cancer
    Group Young Researchers in Inflammatory Carcinogenesis, Anna Maxi Wandmacher, Anne‐Sophie Mehdorn, Susanne Sebens · 2021 · Cancers
  72. S100A2 Is a Prognostic Biomarker Involved in Immune Infiltration and Predict Immunotherapy Response in Pancreatic Cancer
    Yuan Chen, Chengcheng Wang, Jianlu Song, Ruiyuan Xu, Rexiati Ruze, Yupei Zhao · 2021 · Frontiers in Immunology
  73. Mechanisms of drug resistance of pancreatic ductal adenocarcinoma at different levels
    Jiali Du, Jichun Gu, Ji Li · 2020 · Bioscience Reports
  74. A glitch in the matrix: organ-specific matrisomes in metastatic niches
    Sarah K. Deasy, Neta Erez · 2021 · Trends in Cell Biology
  75. The pan-therapeutic resistance of disseminated tumor cells: Role of phenotypic plasticity and the metastatic microenvironment
    Bo Ma, Alan H. Wells, Amanda M. Clark · 2019 · Seminars in Cancer Biology
  76. Framing cancer progression: influence of the organ‐ and tumour‐specific matrisome
    Maria Rafaeva, Janine Terra Erler · 2020 · FEBS Journal
  77. Paracrine and cell autonomous signalling in pancreatic cancer progression and metastasis
    Stacy K. Thomas, Jesse Lee, Gregory Lawrence Beatty · 2020 · EBioMedicine
  78. The hepatic microenvironment essentially determines tumor cell dormancy and metastatic outgrowth of pancreatic ductal adenocarcinoma
    Lennart Lenk, Maren Pein, Olga Will, Beatriz Aguilar Gomez, Fabrice Viol, Charlotte Hauser, Jan‐Hendrik Egberts, Jan-Paul Gundlach, Ole Helm, Sanjay Tiwari et al. · 2017 · OncoImmunology
  79. Breast Cancer–Secreted Factors Promote Lung Metastasis by Signaling Systemically to Induce a Fibrotic Premetastatic Niche
    Noam Cohen, Dhanashree Mundhe, Sarah K. Deasy, Omer Adler, Nour Ershaid, Tamar Shami, Oshrat Levi-Galibov, Rina Wassermann, Ruth Scherz‐Shouval, Neta Erez · 2023 · Cancer Research
  80. Interplay between interferon regulatory factor 1 and BRD4 in the regulation of PD-L1 in pancreatic stellate cells
    Kazumi Ebine, Krishan Kumar, Thao D. Pham, Mario A. Shields, Katharine Ann Collier, Meng Shang, Brian T. DeCant, Raul A. Urrutia, Rosa F. Hwang, Sam Grimaldo et al. · 2018 · Scientific Reports
  81. Evolution of fibroblasts in the lung metastatic microenvironment is driven by stage-specific transcriptional plasticity
    Ophir Shani, Yael Raz, Lea Monteran, Ye’ela Scharff, Oshrat Levi-Galibov, Or Megides, Hila Shacham, Noam Cohen, Dana Silverbush, Camilla Avivi et al. · 2021 · eLife
  82. Identification of functional heterogeneity of immune cells and tubular-immune cellular interplay action in diabetic kidney disease
    Yunfeng Bai, Kun Chi, Delong Zhao, Wanjun Shen, Ran Liu, Jing Hao, Guangyan Cai, Xiangmei Chen, Quan Hong · 2024 · Journal of Translational Internal Medicine
  83. microRNA-454 shows anti-angiogenic and anti-metastatic activity in pancreatic ductal adenocarcinoma by targeting LRP6.
    Yue Fan, Chenye Shi, Tianyu Li, Tiantao Kuang · 2017 · PubMed Central · Retracted
  84. Adaptive Fibrogenic Reprogramming of Osteosarcoma Stem Cells Promotes Metastatic Growth
    Wu Zhang, Jun-mei Zhao, Jian Lin, Chuan-Zhen Hu, Ji Zhang, WEN-LAN YANG, Junhua Zhang, Jiwang Zhang, Jiang Zhu · 2018 · Cell Reports
  85. The Multiaspect Functions of Periostin in Tumor Progression
    Yingfu Liu, Zhengjie Huang, Dan Cui, Gaoliang Ouyang · 2019 · Advances in experimental medicine and biology
  86. Minimal Residual Disease, Metastasis and Immunity
    Jordi Badia-Ramentol, Jenniffer Linares, Andrea Gómez‐Llonín, Alexandre Calon · 2021 · Biomolecules
  87. Unmasking carcinoma-associated fibroblasts: Key transformation player within the tumor microenvironment
    Qing Meng, Xin Luo, Jiaxin Chen, Di Wang, Engeng Chen, Wei Zhang, Guolin Zhang, Wei Zhou, Jianbin Xu, Zhangfa Song · 2020 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  88. The Origin, Differentiation, and Functions of Cancer-Associated Fibroblasts in Gastrointestinal Cancer
    Jiao Huang, Wai Ying Tsang, Zhihong Li, Xin‐Yuan Guan · 2023 · Cellular and Molecular Gastroenterology and Hepatology
  89. Induction of PGRN by influenza virus inhibits the antiviral immune responses through downregulation of type I interferons signaling
    Fanhua Wei, Zhimin Jiang, Honglei Sun, Juan Pu, Yipeng Sun, Mingyang Wang, Qi Tong, Yuhai Bi, Xiaojing Ma, George F. Gao et al. · 2019 · PLoS Pathogens
  90. Myeloid Cells in Metastasis
    Agnieszka Swierczak, Jeffrey W. Pollard · 2019 · Cold Spring Harbor Perspectives in Medicine
  91. Coadaptation fostered by the SLIT2-ROBO1 axis facilitates liver metastasis of pancreatic ductal adenocarcinoma
    Qing Li, Xiao-Xin Zhang, Li-Peng Hu, Dongxue Li, Dong-Xue Li, Xu Wang, Shu-Heng Jiang, Hui Li, Min-Wei Yang, Yong-Sheng Jiang et al. · 2023 · Nature Communications
  92. Strategy of targeting the tumor microenvironment via inhibition of fibroblast/fibrosis remodeling new era to cancer chemo-immunotherapy resistance
    Mahboubeh Tajaldini, Amirhoushang Poorkhani, Taghi Amiriani, Amirhossein Amiriani, Hossein Javid, Parham Aref, Farahnazsadat Ahmadi, Somayeh Sadani, Vahid Khori · 2023 · European Journal of Pharmacology
  93. It’s all about the base: stromal cells are central orchestrators of metastasis
    Lea Monteran, Yael Zait, Neta Erez · 2023 · Trends in cancer
  94. Mesothelin Secretion by Pancreatic Cancer Cells Co-opts Macrophages and Promotes Metastasis
    Teifion Luckett, Maidinaimu Abudula, Lucy Ireland, Mark A. Glenn, Gaia Bellomo, Ruth Stafferton, Christopher Michael Halloran, Paula Ghaneh, Robert Peter Jones, Michael C. Schmid et al. · 2024 · Cancer Research
  95. Metastasis of pancreatic cancer: An uninflamed liver micromilieu controls cell growth and cancer stem cell properties by oxidative phosphorylation in pancreatic ductal epithelial cells
    Alexander Fabian, Simon Henry Stegner, Lauritz Miarka, Johannes Zimmermann, Lennart Lenk, Sascha Rahn, Jann Buttlar, Fabrice Viol, Hendrike Knaack, Daniela Esser et al. · 2019 · Cancer Letters
  96. Bringing Macrophages to the Frontline against Cancer: Current Immunotherapies Targeting Macrophages
    Mariana Reis-Sobreiro, Afonso Teixeira da Mota, Carolina Jardim, Karine Serre · 2021 · Cells
  97. PGRN exacerbates the progression of non-small cell lung cancer via PI3K/AKT/Bcl-2 antiapoptotic signaling
    Sicheng Chen, Mengjun Bie, Xiaowen Wang, Mengtian Fan, Bin Chen, Qiong Shi, Yingjiu Jiang · 2021 · Genes & Diseases
  98. Pericytes cross-talks within the tumor microenvironment
    Caroline C. Picoli, Bryan Ôrtero Perez Gonçalves, Gabryella S. P. Santos, Beatriz G. S. Rocha, Alinne C. Costa, Rodrigo R. Resende, Alexander Birbrair · 2021 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  99. Role of T cells in liver metastasis
    Kejia Wu, Guozhu Zhang, Changbing Shen, Li Zhu, Chongyuan Yu, Kurt Sartorius, Wei Ding, Yong Jiang, Yunjie Lu · 2024 · Cell Death and Disease
  100. miR-15/107 microRNA Gene Group: Characteristics and Functional Implications in Cancer
    Chiara Turco, Sara Donzelli, Giulia Fontemaggi · 2020 · Frontiers in Cell and Developmental Biology