Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer

Herranz, Daniel, Muñoz-Martin, Maribel, Cañamero, Marta, Mulero, Francisca, Martinez-Pastor, Barbara, Fernandez-Capetillo, Oscar, Serrano, Manuel·2010·Nature Communications
DOI 10.1038/ncomms1001

Cited by (611)

Items 501–600 of 611

  1. Immunohistochemical examination of osteopontin and sirtuin-1 expression in cattle tuberculosis
    M Sevtekin, Özlem Özmen · 2018 · Biotechnic & Histochemistry
  2. The Role of NAD+ in Anti-Aging Therapies
    Xu-Qian Liu, Tao-Sheng Huang · 2019 · American Journal of Biomedical Science & Research
  3. SIRT1 in Metabolic Health and Disease
    Marie Boutant, Carles Cantó · 2016 · Springer eBooks
  4. The effect of aerobic training with Citrus aurantium L. on SIRT1 and PGC-1α gene expression levels in the liver tissue of elderly rats
    Zinab Shykholeslami, Ahmad Abdi, Alireza Barari, Seyed Ali Hosseini · 2019 · Jorjani Biomedicine Journal
  5. Dietary restriction and Sirtuin 1 in metabolic health: connections and divergences
    Carles Cantó · 2015 · Proceedings of The Nutrition Society
  6. Sirtuins, healthspan, and longevity in mammals
    Surinder Kumar, William Giblin, David B. Lombard · 2021 · Elsevier eBooks
  7. Melatonin in Aging and Aging-Related Disorders
    Síbel Süzen · 2023 · Springer eBooks
  8. Reprint of “DNA, the central molecule of aging”
    Peter Lenárt, Lumír Krejčí · 2016 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
  9. Central Mechanisms Linking Age-Associated Physiological Changes to Health Span Through the Hypothalamus
    Akiko Satoh · 2022 · Springer eBooks
  10. Sirtuin-Dependent Metabolic Control and Its Role in the Aging Process
    Sara Santa-Cruz Calvo, Plácido Navas, Guillermo López‐Lluch · 2012 · InTech eBooks
  11. Aging Kidney: Modern Perspectives for an ‘Old’ Problem
    Fabrizio Grosjean, Helen Vlassara, Gary E. Striker · 2011 · Aging Health
  12. Complex roles of Sirtuin 1 in cancer and aging
    Zhiping Liu, Liou Y. Sun · 2011 · Translational research
  13. Has Anyone so far Bridged the Gap between microRNA, Botanicals and Oropharyngeal Squamous Cell Carcinoma?
    Mohammed EL-Awady Grawish · 2014 · Alternative & Integrative Medicine
  14. Le silence parlant de la sirtuine 1 dans la stéatose et le cancer du foie
    Hélène Gilgenkrantz, Christine Perret · 2012 · médecine/sciences
  15. Sirtuins: A Future Perspective
    Brian Keith Kennedy · 2016 · Springer eBooks
  16. Sirtuins and Aging
    Carles Cantó, Riekelt H. Houtkooper · 2016 · Springer eBooks
  17. Sirtuins and aging
    Brian J. Morris · 2021 · Elsevier eBooks
  18. Chronic liquid fructose supplementation does not cause liver tumorigenesis but elicits clear sex differences in the metabolic response in Sprague–Dawley rats
    Núria Roglans, Miguel Baena, Gemma Sangüesa, Ana Magdalena Velázquez, Christian Griñán‐Ferré, Mercè Pallàs, Rosa María Sánchez, Marta Alegret, Juan Carlos Laguna · 2021 · Food & Nutrition Research
  19. The Controversy Around Sirtuins and Their Functions in Aging
    Yu Sun, Weiwei Dang · 2016 · Elsevier eBooks
  20. The bifunctional roles of sirtuins and their therapeutic potential in cancer
    Yeuan Ting Lee, Yi Jer Tan, Pei Yi Mok, Ayappa V. Subramaniam, Chern Ein Oon · 2021 · Elsevier eBooks
  21. Biomedical Research in Aging
    José Mario González-Meljem, Scott Haston, Suchira Gallage, Andrew J. Innes · 2018 · Springer eBooks
  22. The Protective Effect of Dihydroartemisinin on Type 2 Diabetic Mice via Regulating Hepatic Glucose Output
    Yu Zhang, Yuanmin Yang, Shuiqing Qu, Shuoqiu Deng, Li Yu, Zhong-yuan Zheng, Yue Dai, Tuo Liu, Lina Chen, Yujie Li · 2024 · Journal of Biomedical Nanotechnology
  23. Tunable Hypersonic Resonators via Electron‐Irradiation‐Induced Giant Modulation of Microparticle Elasticity
    Francesco Bonacci, Francesco Cottone, Alessandro Di Michele, Alessandra Anna Passeri, M. Madami, Silvia Caponi, M. Mattarelli · 2025 · Small
  24. Assessment of sub-chronic toxicity and anti-aging effects of a solid self-microemulsifying drug delivery system of Kaempferia parviflora extract in a D-galactose-induced rat model
    Somsuda Somintara, Waraporn Sakaew, Sarunya Tuntiyasawasdikul, Peera Tabboon, Catheleeya Mekjaruskul, Jenjiralai Phanphak, Choowadee Pariwatthanakun, Bungorn Sripanidkulchai, Tawut Rudtanatip · 2026 · Pharmaceutical Biology
  25. Circadian rhythms, NRF2 signalling and redox homeostasis: A holy grail for a healthy life course?
    Elizabeth Sutton, Vanja Pekovic‐Vaughan · 2026 · Free Radical Biology and Medicine
  26. The SIRT Family: Subcellular Localization and Main Functions
    Ping Quan, Christoph Schatz, Daria Maria Filippini, Johannes Haybaeck · 2026 · International Journal of Molecular Sciences
  27. Chromatin Signaling in Aging and Cellular Senescence
    Florence Couteau, Frédérick A. Mallette · 2016 · Elsevier eBooks
  28. SIRT1 as a key factor for histone code establishment in early embryo, from a perspective of assisted reproduction
    Jan Nevoral, Peter Šutovský, Kateřina Zámostná, Aleš Petelák, Kristýna Hošková, Tereza Žalmanová, Jaroslav Petr · 2015 · Slovak Journal of Animal Science
  29. Why we age — a new evolutionary view
    Igor Peregrim · 2017 · Biologia
  30. Prognostic Significance of Sirtuins Expression in Papillary Thyroid Carcinoma
    Yea Eun Kang, Minho Shong, Jin‐Man Kim, Bon Seok Koo · 2018 · International Journal of Thyroidology
  31. Protective Effects of Maprotiline in 6-Hydroxydopamine (6-OHDA)-Induced Ferroptosis in Neuronal Cells
    Hong Bo Cheng, Ying Chen, Haifan Yang, Xin Tang, Weiyi Zhu · 2022 · Journal of Biomedical Nanotechnology
  32. Insulin-Like Growth Factor 2 mRNA Binding Protein 3 Suppresses Ferroptosis in Non-Small Cell Lung Cancer via Stabilizing m6A Modification of Fanconi Anemia Group D2 Protein
    Haotian Zhang, Junjie Tang, Xiaowei Gong, Chenjun Huang · 2023 · Journal of Biomedical Nanotechnology
  33. Circadian Clocks in Ageing
    Pei Zhu, Clara Bien Peek · 2024 · Royal Society of Chemistry eBooks
  34. Combat Ageing by Sirtuins and Sirtfoods: Genetic and Dietary way of reducing senescence
    Radhika Sharma · 2023 · International Journal of Technology
  35. Transcriptional Regulation in the Control of Aging and Longevity
    Olga Y. Rybina, ELENA G. PASYUKOVA · 2023 · Advances in Gerontology
  36. Alternsumkehr und Lebensspannenverlängerung
    Leo Cornelius Bollheimer, Dorothee Volkert, Thomas Bertsch, Cornel Christian Sieber, Reinhard Büttner · 2012 · Zeitschrift für Gerontologie und Geriatrie
  37. Longevity Pathways in Mammalian Stem Cells
    Anne Brunet, Salah Mahmoudi, Elena Mancini, Victoria A. Rafalski, Ashley E. Webb · 2014 · Annual Review of Gerontology and Geriatrics
  38. Aging in the Single-Celled Eukaryote, S. cerevisiae
    Chong Z. He, Brian Keith Kennedy · 2015 · Springer eBooks
  39. Sirtuins as Markers of Bone Disease: A Focus on Osteoarthritis and Osteoporosis
    Élie Abed, Pascal Reboul, Daniel Lajeunesse · 2016 · Exposure and Health
  40. Sirtuins and Stress Response in Skin Cancer, Aging, and Barrier Function
    Yu‐Ying He · 2016 · Springer eBooks
  41. Computational model of circadian oscillator in mammals: Interaction with NAD+/SIRT1 system and age-related changes in the expression of circadian oscillator genes
    N. L. Podkolodnyy, Natalya N. Tverdokhleb, Olga A. Podkolodnaya · 2017 · Russian Journal of Genetics Applied Research
  42. Nutrition in the Elderly
    Eugenio Mocchegiani · 2016 · Elsevier eBooks
  43. Resveratrol Inhibitory Effects Against a Malignant Tumor: A Molecular Insight
    Gabriel Wcisło · 2018 · Elsevier eBooks
  44. State of Knowledge and Recent Advances in Prevention and Treatment of Mitochondrial Dysfunction in Obesity and Type 2 Diabetes
    Carles Cantó · 2019 · Elsevier eBooks
  45. Reduced Coenzyme Q10 Decelerates Senescence and Age-Related Hearing Loss in Senescence-Accelerated Mice by Activating Mitochondrial Functions.
    Jinko Sawashita, Zhe Xu, Keiichi Higuchi · 2020 · Springer eBooks
  46. Effect of caloric restriction on alveolar bone loss in rats
    Evelyn Lopez Soares, Fábio André dos Santos, Tayline Mroczek, Debora Cristina de Lima, Hemily Victória Bardini Josefino, Luise Adrieli Bochenek da Silva, Leomar Emanuel Almeida Mecca, Gilson César Nobre Franco · 2021 · Life Sciences
  47. Organic‐Polymer‐Based Photodetectors: Mechanism and Device Fabrication
    Nasrin Sultana, Indranee Hazarika, Bedanta Gogoi · 2024
  48. Carcinogenic Compounds, 2-nitrofluorene and Clonidine Can Modulate the Level of Sirtuin mRNAs Expression in Human Adipose Tissue-derived Stem Cells
    Jiyoun Lee, Chae-yeong Lee, Young-Ho Kwon, Ho-Chan Kim, Hyun Kim · 2014 · Korean Journal of Physical Anthropology
  49. The Role of Sirtuins in Arthritis
    Diego Kyburz, Fabienne Niederer · 2012 · Springer eBooks
  50. Relationship of common expression quantitative trait loci genes to the immune system.
    Jin Li, Lin-Jie Wang, Huixin Li, Rong Zhang, Xia Li, Mao-Zu Guo · 2013 · Genetics and Molecular Research
  51. Mediators and markers of mammalian lifespan extension: Proteomic, proliferative and hormonal adaptations in mouse models of extended lifespan
    Airlia C. S. Thompson · 2014 · ProQuest Demo Repository
  52. SIRT2: in the crossroad of aging, neurodegeneration and autophagy
    Renato Martinho · 2013 · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)
  53. The Way Forward: Translation
    James L. Kirkland, Tamar Tchkonia · 2015 · Springer eBooks
  54. Progeria and Genome Instability
    Fanbiao Meng, Baohua Liu, Zhongjun Zhou · 2015 · Springer eBooks
  55. The Role of Sirtuin 6 in Maintaining Vascular Integrity
    Sharon Z Leung · 2016 · Scholarship@Western (Western University)
  56. Nuclear Chromatin Factors Defining Mitochondrial Bioenergetics
    Pere Puigserver, Leonard Guarente · 2012 · Oxidative stress and disease
  57. Therapeutic Strategies for Metabolic Syndrome and Lifestyle-Related Disease
    Hajime Otani · 2013 · CRC Press eBooks
  58. NAD + -Dependent Deacetylases and Medical Therapy
    Ashok Kumar, Louisa Ben-Aderet, Jinan Elayyan, Mona Dvir‐Ginzberg · 2016 · Elsevier eBooks
  59. Sirtuins in Cancer – Emerging Role as Modulators of Metabolic Reprogramming
    Jaewon James Lee, Karina N. Gonzalez Herrera, Marcia C. Haigis · 2016 · Springer eBooks
  60. Def-eating senescence?
    Giuseppe Maulucci, Giovambattista Pani · 2012
  61. A Role for Sirtuins in Maintaining Mammalian Lifespan and Healthspan
    William Giblin · 2017 · Deep Blue (University of Michigan)
  62. The Role of Resveratrol and Sirtuin1 in Skeletal Muscle Under a Nutrient Stress
    Hannah F. Dugdale · 2017 · Liverpool John Moores University
  63. Line-1 Retrotransposition and the Impact on Aging Rodent Skeletal Muscle Tissue
    Petey W. Mumford · 2019
  64. 小鼠心脏过表达SIRT1显性失活突变体导致心肌细胞凋亡和早发性心衰
    云彪 鲁, 伟 郑, 厚早 陈, 文利 穆, 志刚 折, 德培 刘, 玉生 韦, 文艳 付, 小强 唐, 红良 李 et al. · 2014 · Scientia Sinica Vitae
  65. SIRT1 mediates obesity- and nutrient-dependent perturbation of pubertal timing by epigenetically controlling Kiss1 expression
    Vazquez MJ, Toro CA, Castellano JM, Francisco Ruíz-Pino, Juan Roa, Daniel Beiroa, Violeta Heras, Inmaculada Velasco, Carlos Diéguez, Lucía Pinilla et al. · 2019 · Yearbook of pediatric endocrinology
  66. Eating Habits and Their Impact on Aging and Cancer
    Fabio Marongiu, Monica Serra, Ezio Laconi · 2019 · Royal Society of Chemistry eBooks
  67. A Possible Beneficial Effect of Sex Hormones on Vascular Aging through Expression of Sirtuin 1 Gene: A Narrative Review of the Literature
    Takafumi Tsuchiya, Toshihiko Inukai, Kenji Hara, Kohzo Takebayashi, Koshi Hashimoto · 2020 · Gene Technology
  68. Sirtuins in Aging
    Brian J. Morris · 2019 · Springer eBooks
  69. Molecular Context of ADP-ribosylation in Schistosomes for Drug Discovery and Vaccine Development
    Amandla Chutshela, Priscilla Masamba, Babatunji Emmanuel Oyinloye, Abidemi Paul Kappo · 2020 · Current Drug Discovery Technologies
  70. Sirtuins in aging, age-related pathologies and their association with circadian rhythm
    Sankarathi Balaiya · 2021 · Elsevier eBooks
  71. MECHANISMS OF G PROTEIN-COUPLED RECEPTOR 2 REGULATION AND INHIBITION IN CARDIOVASCULAR DISEASE AND AGING
    Melissa Lieu · 2020 · TUScholarShare (Temple University)
  72. Sirtuins and life span extension
    Shin‐Hae Lee, Kyung‐Jin Min · 2021 · Elsevier eBooks
  73. Sirtuin signaling in hematologic malignancies
    Ryan Austin Denu · 2021 · Elsevier eBooks
  74. Alternsumkehr und Lebensspannenverlängerung: Aktuelle biomedizinische Schlüsselpublikationen und ihre Implikationen für die Geriatrie
    Leo Cornelius Bollheimer, Dorothee Volkert, Thomas Bertsch, Cornel Christian Sieber, Reinhard Büttner · 2013 · Zeitschrift für Gerontologie und Geriatrie
  75. Sirtuins in Aging
    Brian J. Morris · 2021 · Springer eBooks
  76. Efeito da obesidade sobre a s-nitrosação da SIRT1 no tecido hepático e no músculo esquelético de camundongos
    Luciene Lenhare · 2018
  77. Introduction
    Shrestha Ghosh · 2019 · Springer theses
  78. Faculty Opinions recommendation of The hallmarks of aging.
    Ian David Hickson, Hocine W Mankouri · 2013 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  79. Effect Of Puerarin on The Growth of Nasopharyngeal Carcinoma Cells and Its Impact on Angiogenesis
    Yepeng Li, Jingjing Zhao, Bo Yang · 2022 · Cancer Research and Cellular Therapeutics
  80. Sirtuins as Markers of Bone Disease: A Focus on Osteoarthritis and Osteoporosis
    Élie Abed, Pascal Reboul, Daniel Lajeunesse · 2017 · Biomarkers in disease
  81. Caracterização da S-nitrosação da SIRT1 no músculo esquelético em modelo experimental de envelhecimento
    Luciene Lenhare · 2014
  82. Faculty Opinions recommendation of Phosphorylated SIRT1 associates with replication origins to prevent excess replication initiation and preserve genomic stability.
    Catherine A. Fox · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  83. Neurodegeneração no Envelhecimento: Lições da Síndrome de Cockayne
    Lívia Luz Souza Nascimento · 2022
  84. Papel da sirtuína 1 no fenótipo e função de células dendríticas no contexto do transplante em animais obesos
    Jean de Lima · 2021
  85. Inhibition of Senescence Through Decreasing P16ink4a Expression by Sirt-1 in ADMA Exposed EPC
    Titin Andri Wihastuti, Wiwit Nurwidyaningtyas, Kumboyono Kumboyono · 2023 · Advances in economics, business and management research/Advances in Economics, Business and Management Research
  86. Synthesis, Characteristics and Applications of Graphene Composites: A Survey
    Biswajit Dalai, B. P. Patra, Niharika DAS, Ruturaj SAHOO, D. K. Sahoo, Chhatrapati Parida, Sarat Kumar Dash · 2023 · Journal of the Turkish Chemical Society Section A Chemistry
  87. The role of Banf1 in mechanisms of cellular ageing and cancer prognosis
    Jennifer Plowman · 2024 · Queensland University of Technology
  88. Characterization of Immunogenic Cell Death Related Molecular Subtypes and Its Therapeutic Implications for Prostate Adenocarcinoma
    Jie Yang, Chao Wang, Chuan Zhou, Zijian Da, Fenghai Zhou · 2024 · Journal of Biomedical Nanotechnology
  89. Efect of N-acetylcysteine on HepG2 cells which were induced into fatty liver cells
    Mohammadreza Gholamrezapour, Raziyeh Taghizadeh Ghavamabadi, Mohammad Mohsen Taghavi, Samereh Dehghani Soltani, Ahmad Shabanizadeh, Reza Vazirinejad, Zahra Taghipour · 2024 · Journal of Molecular Histology
  90. Biomedical Research in Aging
    José Mario González-Meljem, Scott Haston, Suchira Gallage, Andrew J. Innes, Christian Quintus Scheckhuber · 2024 · Springer eBooks
  91. Effect of aging and obesity on peripheral t3 generation and thyroidal status in congenic la/ntul//cp rats
    Orien L. Tulp · 2024 · Endocrinology&Metabolism International Journal
  92. 37 kDa LRP::FLAG enhances telomerase activity and reduces ageing markers in vivo
    Tyrone C. Otgaar, Martin Bernert, Gavin Morris, Pavan Baichan, Monique J. Bignoux, Boitelo T. Letsolo, Stefan F. T. Weiss, Eloise Ferreira · 2025 · Cellular and Molecular Life Sciences
  93. The Role of NAD+-Dependent Signal Mechanisms in Cancer Development and Treatment
    Ting Lu, Zheng‐Hong Qin, Junchao Wu · 2025 · Springer eBooks
  94. Characteristics of gastric emptying on glycemic responses in the T2DM-SHR/Ntul//-cp (Corpulent) rat
    Orien L. Tulp · 2025 · Gastroenterology & Hepatology Open Access
  95. SIRT1 limits neuronal fate following DNA damage
    Christian Kroll, Bilhan Karacora, Sven Guenther Meuth, Gerhard Fritz, Orhan Aktaş, Carsten Berndt, Tim Prozorovski · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  96. Genetic insights from long-lived mammals
    Shiying Li, Hayeun Kim, Seung Joon Baek · 2025 · Journal of Veterinary Science
  97. Additional file 1 of Interaction of Sirtuin 1 (SIRT1) candidate longevity gene and particulate matter (PM2.5) on all-cause mortality: a longitudinal cohort study in China
    Yao, Yao, Liu, Linxin, Guang Guo, Zeng, Yi, Ji, John S. · 2021 · Figshare
  98. Red ginseng-derived components attenuate UVB-induced keratinocyte senescence via senomorphic mechanisms
    Sung Ha Lim, Hee Seok Seo, Hyun Kang, Seung-Phil Hong · 2026 · Journal of Ginseng Research
  99. Low protein diet induced anti-cancer immune response
    Jozef P. Bossowski · 2018
  100. Rôle et régulation de l'haptoglobine adipocytaire au cours du vieillissement
    Gwendoline Astre · 2018 · theses.fr (ABES)