Locus-specific histone deacetylation using a synthetic CRISPR-Cas9-based HDAC

Kwon, Deborah Y., Zhao, Ying-Tao, Lamonica, Janine M., Zhou, Zhaolan·2017·Nature Communications
DOI 10.1038/ncomms15315

Cited by (247)

Items 101–200 of 247

  1. Intrauterine Hypoxia and Epigenetic Programming in Lung Development and Disease
    Yajie Tong, Shuqing Zhang, Suzette R. Riddle, Li Zhang, Rui Song, Dongmei Yue · 2021 · Biomedicines
  2. Comprehensive computational analysis of epigenetic descriptors affecting CRISPR-Cas9 off-target activity
    Jeffrey Kelvin Mak, Florian Störtz, Péter Mináry · 2022 · BMC Genomics
  3. CRISPR editing in biological and biomedical investigation
    Jiaojiao Huang, Yanfang Wang, Jianguo Zhao · 2017 · Journal of Cellular Physiology
  4. Therapeutic application of the CRISPR system: current issues and new prospects
    Minyoung Lee, Seokjoong Kim · 2019 · Human Genetics
  5. Chemical and Light Inducible Epigenome Editing
    Weiye Zhao, Yufan Wang, Fu‐Sen Liang · 2020 · International Journal of Molecular Sciences
  6. Applications of CRISPR-Cas in Bioengineering, Biotechnology, and Translational Research
    Cia‐Hin Lau · 2018 · The CRISPR Journal
  7. A viral toolkit for recording transcription factor–DNA interactions in live mouse tissues
    Alexander J. Cammack, Arnav Moudgil, Jiayang Chen, Michael J. Vasek, Mark Shabsovich, Katherine B. McCullough, Allen Yen, Tomás Lagunas, Susan E. Maloney, June He et al. · 2020 · Proceedings of the National Academy of Sciences
  8. Epigenetic Regulation of β-Globin Genes and the Potential to Treat Hemoglobinopathies through Epigenome Editing
    Letizia Fontana, Zoe Alahouzou, Annarita Miccio, Panagiotis Antoniou · 2023 · Genes
  9. Advances and Opportunities in Epigenetic Chemical Biology
    Jenna N. Beyer, Nicole R. Raniszewski, George M. Burslem · 2020 · ChemBioChem
  10. Targeting the Post-translational Proteome with Intrabodies
    Antonino Cattaneo, Michele Chirichella · 2018 · Trends in biotechnology
  11. Transcriptional enhancers: from prediction to functional assessment on a genome-wide scale
    Ian C. Tobias, Luis E. Abatti, Sakthi D. Moorthy, Shanelle Mullany, Tiegh Taylor, Nawrah Khader, Mario Filice, Jennifer A. Mitchell · 2020 · Genome
  12. CRISPR-Based Genome-Editing Tools for Huntington’s Disease Research and Therapy
    Yiyang Qin, Shihua Li, Xiao‐Jiang Li, Su Yang · 2022 · Neuroscience Bulletin
  13. Current therapies for osteoarthritis and prospects of CRISPR-based genome, epigenome, and RNA editing in osteoarthritis treatment
    Yuxi Chen, Xiao Ling Luo, Rui Kang, Kaixin Cui, Jianping Ou, Xiya Zhang, Puping Liang · 2023 · Journal of genetics and genomics/Journal of Genetics and Genomics
  14. Aldosterone induces renal fibrosis by promoting HDAC1 expression, deacetylating H3K9 and inhibiting klotho transcription
    Lingyun Lai, Ping Cheng, Minhua Yan, Yong Gu, Jun Xue · 2018 · Molecular Medicine Reports
  15. Adaptation or pathology? The role of prenatal stressor type and intensity in the developmental programing of adult phenotype
    Sophie St-Cyr, Patrick O. McGowan · 2017 · Neurotoxicology and Teratology
  16. Blossom of CRISPR technologies and applications in disease treatment
    Huayi Liu, Lian Wang, Yunzi Luo · 2018 · Synthetic and Systems Biotechnology
  17. Chromatin Manipulation and Editing: Challenges, New Technologies and Their Use in Plants
    Kateryna Fal, Denisa Tomková, Gilles Vachon, Marie‐Edith Chabouté, Alexandre Berr, Cristel C. Carles · 2021 · International Journal of Molecular Sciences
  18. Epigenetics of Hypertensive Nephropathy
    Yize Zhang, Hamidreza Arzaghi, Zhehan Ma, Yasmin Roye, Samira Musah · 2024 · Biomedicines
  19. Unlocking the metabolic potential of endophytic fungi through epigenetics: a paradigm shift for natural product discovery and plant–microbe interactions
    Rui Liu, Xiao-Ping Peng, David J. Newman, Diane Purchase, Gang Li, Souvik Kusari · 2025 · Natural Product Reports
  20. Next-generation CRISPR technology for genome, epigenome and mitochondrial editing
    Cia‐Hin Lau, Qingle Liang, Haibao Zhu · 2024 · Transgenic Research
  21. Recent advances and current status of gene therapy for epilepsy
    Aojie Cai, Kai Gao, Fan Zhang, Yuwu Jiang · 2024 · World Journal of Pediatrics
  22. Recent advances in neuroepigenetic editing
    Song‐Jun Xu, Elizabeth A. Heller · 2019 · Current Opinion in Neurobiology
  23. CRISPR-dcas9 Optogenetic Nanosystem for the Blue Light-Mediated Treatment of Neovascular Lesions
    Jiahua Li, Yafeng Hao, Huizhuo Pan, Yingying Zhang, Guohui Cheng, Baona Liu, Jin Keun Chang, Hanjie Wang · 2021 · ACS Applied Bio Materials
  24. The Multiple Myeloma Landscape: Epigenetics and Non-Coding RNAs
    Isabel F. Coira, Rafael Rincón, Muriel Cuendet · 2022 · Cancers
  25. The diverse roles of histone 2B monoubiquitination in the life of plants
    Fauzia Zarreen, Mir Jishan Karim, Supriya Chakraborty · 2022 · Journal of Experimental Botany
  26. Overcoming the Limitations of CRISPR-Cas9 Systems in Saccharomyces cerevisiae: Off-Target Effects, Epigenome, and Mitochondrial Editing
    Genki Edward Sato, Kouichi Kuroda · 2023 · Microorganisms
  27. Active fusions of Cas9 orthologs
    Goran Josipović, Vlatka Zoldoš, Aleksandar Vojta · 2019 · Journal of Biotechnology
  28. Genome editing in grass plants
    Si Nian Char, Bing Yang · 2019 · aBIOTECH
  29. Identification of stress-induced epigenetic methylation onto dopamine D2 gene and neurological and behavioral consequences
    Blum, Kenneth, Bowirrat, Abdalla, Baron, David, Elman, Igor, Makale, Milan T., Cadet, Jean Lud, Thanos, Panayotis K., Hanna, Colin, Ahmed, Rania, Gondre-Lewis, Marjorie C. et al. · 2024 · Gene & Protein in Disease
  30. Cell-type specific profiling of histone post-translational modifications in the adult mouse striatum
    Marco D. Carpenter, Delaney K. Fischer, Shuo Zhang, Allison M. Bond, Kyle S. Czarnecki, Morgan T. Woolf, Hongjun Song, Elizabeth A. Heller · 2022 · Nature Communications
  31. Gene editing in common cardiovascular diseases.
    Anna-Maria Lauerer, Xurde M. Caravia, Lars S. Maier, Francesco Chemello, S. Lebek · 2024 · Pharmacology and Therapeutics
  32. Regulation of Gene Expression and the Elucidative Role of CRISPR-Based Epigenetic Modifiers and CRISPR-Induced Chromosome Conformational Changes
    Andrea Martella, David I. Fisher · 2021 · The CRISPR Journal
  33. CRISPR‐Cas system: Toward a more efficient technology for genome editing and beyond
    Vahideh Ahmadzadeh, Safar Farajnia, Roghayyeh Baghban, Leila Rahbarnia, Habib Zarredar · 2019 · Journal of Cellular Biochemistry
  34. Convergent biological pathways underlying the Kallmann syndrome-linked genes Hs6st1 and Fgfr1
    Sohyun Moon, Ying-Tao Zhao · 2022 · Human Molecular Genetics
  35. Genetic and epigenetic editing in nervous system
    Jeremy J. Day · 2019 · Dialogues in Clinical Neuroscience
  36. Epigenomic technologies for precision oncology
    Dieter Weichenhan, Daniel B. Lipka, Pavlo Lutsik, Ashish Goyal, Christoph Plass · 2020 · Seminars in Cancer Biology
  37. Deciphering the regulatory landscape of enhancer RNAs in health and disease
    Qian Wang, Peter ten Dijke, Chuannan Fan · 2026 · Signal Transduction and Targeted Therapy
  38. Targeting neuronal epigenomes for brain rejuvenation
    Sara Zocher · 2024 · The EMBO Journal
  39. Epigenetic Editing in Prostate Cancer: Challenges and Opportunities
    Mariana Brütt Pacheco, Vânia Camilo, Rui Henrique, Cármen Jerónimo · 2021 · Epigenetics
  40. CRISPR-Based Tools for Fighting Rare Diseases
    Qingyang Li, Yanmin Gao, Haifeng Wang · 2022 · Life
  41. Synergistic Integration of HDAC Inhibitors and Individualized Neoantigen Therapy (INT): A Next-Generation Combinatorial Approach for Cancer Immunotherapy
    Rui Han, Huiling Zhou, Baoqing Peng, Shasha Yu, Jiajie Zhu, Jiaojiao Chen · 2025 · Vaccines
  42. Translating GWAS in rheumatic disease: approaches to establishing mechanism and function for genetic associations with ankylosing spondylitis
    Julie A. Osgood, Julian Charles Knight · 2018 · Briefings in Functional Genomics
  43. Applying CRISPR-Cas9 screens to dissect hematological malignancies
    Deepak Narayanan Iyer, Aaron David Schimmer, Hong Chang · 2022 · Blood Advances
  44. A CRISPR reimagining: New twists and turns of CRISPR beyond the genome‐engineering revolution
    Robert J. Plummer, Yi Guo, Ying Peng · 2017 · Journal of Cellular Biochemistry
  45. CRISPR-dCas9 system for epigenetic editing towards therapeutic applications
    Gargi Bhattacharjee, Nisarg Gohil, Deepak Siruka, Khushal Khambhati, Rupesh Maurya, Suresh Ramakrishna, Dinh‐Toi Chu, Vijai Singh · 2023 · Progress in molecular biology and translational science
  46. CRISPR-Cas9 Direct Fusions for Improved Genome Editing via Enhanced Homologous Recombination
    Tahmina Tabassum, Giovanni Pietrogrande, Michael D. Healy, Ernst Jurgen Wolvetang · 2023 · International Journal of Molecular Sciences
  47. An overview of applications of CRISPR-Cas technologies in biomedical engineering
    Saleh Jamehdor, Kasra Arbabi Zaboli, Sina Naserian, Jose Thekkiniath, Honey Alef Omidy, Ali Teimoori, Behrooz Johari, Amir Hossein Taromchi, Yu Sasano, Saeed Kaboli · 2020 · Folia Histochemica et Cytobiologica
  48. Characterization of Rationally Designed CRISPR/Cas9-Based DNA Methyltransferases with Distinct Methyltransferase and Gene Silencing Activities in Human Cell Lines and Primary Human T Cells
    Rosa Selenia Guerra-Resendez, Samantha LeGoff Lydon, Alex J. Ma, Guy C. Bedford, Daniel R. Reed, Sung Hwan Kim, Erik R. Terán, Tomoki Nishiguchi, Mario Escobar, Andrew R. DiNardo et al. · 2025 · ACS Synthetic Biology
  49. Viewing AML through a New Lens: Technological Advances in the Study of Epigenetic Regulation
    Laura Godfrey, Alba Rodríguez-Meira · 2022 · Cancers
  50. dCas9 Tells Tales: Probing Gene Function and Transcription Regulation in Cancer
    Nurul Nadia Mohamad Zamberi, Asmaa Y. Abuhamad, Teck Yew Low, M. Aiman Mohtar, Saiful Effendi Syafruddin · 2024 · The CRISPR Journal
  51. Advances in CRISPR-Cas systems for epigenetics
    Mahnoor Ilyas, Qasim Shah, Alvina Gul, Huzaifa Ibrahim, Rania Fatima, Mustafeez Mujtaba Babar, Jayakumar Rajadas · 2024 · Progress in molecular biology and translational science
  52. Development of Toolboxes for Precision Genome/Epigenome Editing and Imaging of Epigenetics
    Wataru Nomura · 2018 · The Chemical Record
  53. Epigenetic mechanisms and next-gen editing platforms in hematology: From molecular basis to therapeutic frontiers
    Minzhi Huang, Ahmad Ewadi, Nazli Servatian, Hanieh Noormohamadi, Zafar Aminov, Khursheed Muzammil, Mahdis Abdar Esfahani, Niloofar Abak, Hamed Soleimani Samarkhazan · 2025 · Critical Reviews in Oncology/Hematology
  54. On RNA-programmable gene modulation as a versatile set of principles targeting muscular dystrophies
    Sabrina Capelletti, Sofía C García Soto, Manuel A.F.V. Gonçalves · 2024 · Molecular Therapy
  55. CRISPR Library Screening in Cultured Cardiomyocytes
    Sophia DeLuca, Nenad Bursac · 2022 · Methods in molecular biology
  56. Synergistic strategies: histone deacetylase inhibitors and platinum-based drugs in cancer therapy
    Ekta Shirbhate, Vaibhav Pratap Singh, Rakesh Kore, Biplab Koch, Ravichandran Veerasamy, Amit Kumar Tiwari, Harish Rajak · 2025 · Expert Review of Anticancer Therapy
  57. Disentangling chromatin architecture to gain insights into the etiology of brain disorders
    Janine M. Lamonica, Zhaolan Zhou · 2019 · Current Opinion in Genetics & Development
  58. Gene and epigenetic editing in the treatment of primary ciliopathies
    Elisa Molinari, John Andrew Sayer · 2021 · Progress in molecular biology and translational science
  59. Secondary Metabolite Production in Plant Cell Culture: A New Epigenetic Frontier
    Cassandra Brzycki Newton, Eric M. Young, Susan C. Roberts · 2021 · Springer eBooks
  60. Epigenome editing and epigenetic gene regulation in disease phenotypes
    Gaochen Jin, Bomyi Lim · 2022 · Korean Journal of Chemical Engineering
  61. Plant Mutagenesis Tools for Precision Breeding: Conventional CRISPR/Cas9 Tools and Beyond
    Rahul Mahadev Shelake, Dibyajyoti Pramanik, Rajesh Ramdas Waghunde, Jae‐Yean Kim · 2023 · Springer eBooks
  62. Predicting the effect of CRISPR-Cas9-based epigenome editing
    Sanjit Singh Batra, Alan Cabrera, Jeffrey P. Spence, Jacob Goell, Selvalakshmi Selvaraj Anand, Isaac B. Hilton, Yun S. Song · 2026 · eLife
  63. A Decade of Genome Editing: Comparative Review of ZFN, TALEN, and CRISPR/Cas9
    Rajesh Kumar, Taniya Bargoti, Shalini Sengar, Deepali Singh, Vikrant Nain · 2025
  64. Expanded CAG/CTG repeats resist gene silencing mediated by targeted epigenome editing
    Bin Yang, Alicia C. Borgeaud, Marcela Buřičová, Lorène Aeschbach, Oscar Rodríguez‐Lima, Gustavo A. Ruiz Buendía, Cinzia Cinesi, Alysha S Taylor, Tuncay Baubec, Vincent Dion · 2021 · Human Molecular Genetics
  65. Genome editing
    Maura A. McGrail, Tetsushi Sakuma, Leonidas G. Bleris · 2022 · Scientific Reports
  66. Right Ventricle and Epigenetics: A Systematic Review
    Victoria Toro, Naomie Jutras-Beaudoin, Olivier Boucherat, Sébastien Bonnet, Steeve Provencher, François Potus · 2023 · Cells
  67. Histone Acyl Code in Precision Oncology: Mechanistic Insights from Dietary and Metabolic Factors
    Sultan Abda Neja, Wan Mohaiza Dashwood, Roderick H. Dashwood, Praveen Rajendran · 2024 · Nutrients
  68. Emerging CRISPR Therapies for Precision Gene Editing and Modulation in the Cardiovascular Clinic
    Nicholas Legere, John Travis Hinson · 2024 · Current Cardiology Reports
  69. The Synergy between CRISPR and Chemical Engineering
    Cia‐Hin Lau, Chung Tin · 2019 · Current Gene Therapy
  70. Acetylation-Specific Interference by Anti-Histone H3K9ac Intrabody Results in Precise Modulation of Gene Expression
    Simonetta Lisi, Matteo Trovato, Ottavia Vitaloni, Marco Fantini, Michele Chirichella, Paola Tognini, Sara Cornuti, Mario Costa, Marco Groth, Antonino Cattaneo · 2022 · International Journal of Molecular Sciences
  71. Improving Cancer Immunotherapy with CRISPR‐Based Technology
    Zexu Li, Fei Teng · 2020 · Advanced Biosystems
  72. Predicting the effect of CRISPR-Cas9-based epigenome editing
    Sanjit Singh Batra, Alan Cabrera, Jeffrey P. Spence, Jacob Goell, Selvalakshmi S Anand, Isaac B. Hilton, Yun S Song · 2023 · eLife
  73. Induced proximity labeling and editing for epigenetic research
    Chenwei Zhou, Sarah A. Wagner, Fu‐Sen Liang · 2024 · Cell chemical biology
  74. Sperm histone mediated epigenetic inheritance
    Bhupender Singh, Rajeev Kumar Singh, Madan Mohan Chaturvedi, Jogeswar Satchidananda Purohit · 2025 · Biology of Reproduction
  75. Development of Artificial System to Induce Chromatin Loosening in Saccharomyces cerevisiae
    Ryota Yamamoto, Genki Edward Sato, Takamitsu Amai, Mitsuyoshi Ueda, Kouichi Kuroda · 2022 · Biomolecules
  76. Integrative pan-cancer analysis reveals a common architecture of dysregulated transcriptional networks characterized by loss of enhancer methylation
    Jørgen Ankill, Zhi Qiang Zhao, Xavier Tekpli, Elin Hegland Kure, Vessela Nedelcheva Kristensen, Anthony Mathelier, Thomas Fleischer · 2024 · PLoS Computational Biology
  77. Epigenetic Insights into Substance Use Disorder and Associated Psychiatric Conditions
    Ambrose Loc Ngo, Christopher M Ahmad, Niki Gharavi Alkhansari, Linda Nguyen, Huiping Zhang · 2025 · Complex Psychiatry
  78. Dissecting cardiovascular disease-associated noncoding genetic variants using human iPSC models
    Saif Dababneh, Hosna Babini, Verónica Jiménez-Sábado, Sheila S. Teves, Kyoung-Han Kim, Glen F. Tibbits · 2025 · Stem Cell Reports
  79. CRISPR-Cas epigenome editing: improving crop resistance to pathogens
    Alberto Cristian López-Calleja, Juan Carlos Vizuet‐de‐Rueda, Raúl Álvarez-Venegas · 2021 · Elsevier eBooks
  80. Advancing CRISPR-Based Programmable Platforms beyond Genome Editing in Mammalian Cells
    Yasutomi Higashikuni, Timothy K. Lu · 2019 · ACS Synthetic Biology
  81. The CRISPR System and Cancer Immunotherapy Biomarkers
    Vitaly Balan, Jianbin Wang · 2019 · Methods in molecular biology
  82. Targeted Epigenome Editing of Plant Defense Genes via CRISPR Activation (CRISPRa)
    Alberto Cristian López-Calleja, Juan Carlos Vizuet‐de‐Rueda, Raúl Álvarez-Venegas · 2019 · Springer eBooks
  83. Locus-Specific Regulation of Xist Expression Using the CRISPR-Cas9-Based System
    Mingtian Deng, Zifei Liu, BaoBao Chen, Yu Cai, Yongjie Wan, Feng Wang · 2020 · DNA and Cell Biology
  84. Epigenome editing: a novel perspective towards ensuring global food security
    Swapnil Shamrao Baraskar, Anuradha Chetukuri, Venkata Chanda Sameer Kumar, Satendra Kumar Mangrauthia · 2024 · The Nucleus
  85. Integration of CTCF loops, methylome, and transcriptome in differentiating LUHMES as a model for imprinting dynamics of the 15q11-q13 locus in human neurons
    Orangel J. Gutierrez Fugón, Osman Sharifi, Nicholas G. Heath, Daniela C. Soto, J. Antonio Gomez, Dag H. Yasui, Aron Judd P. Mendiola, Henriette O’Geen, Ulrika Beitnere, Markéta Tomková et al. · 2024 · Human Molecular Genetics
  86. CRISPR technology for immuno-oncology applications
    Jianbin Wang, Vitaly Balan, Francesco Maria Marincola · 2019 · Methods in enzymology on CD-ROM/Methods in enzymology
  87. In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing.
    A. Migliara, Martino Alfredo Cappelluti, Francesca Giannese, Sara Valsoni, Alberto Coglot, I. Merelli, D. Cittaro, A. Lombardo · 2023 · Journal of Visualized Experiments
  88. Clinical translation of epigenome editing technologies
    Alex J. Ma, Blake H. Brown, Sunghwan Kim, Isaac B. Hilton · 2026 · Current Opinion in Biomedical Engineering
  89. Epigenetic Tools in Chronic Pain Studies
    Guang Bai, Ke Ren · 2018 · Elsevier eBooks
  90. The Effect Of Molecular Genetic Mechanisms On Drug Addiction And Related New Generation CRISPR Gene Engineering Applications
    Ebru Akyürek, Buket Uysal, Gamze Gülden, Cihan Taştan · 2021 · Gene Editing
  91. The transformational impact of site-specific DNA modifiers on biomedicine and agriculture
    Kathryn M. Polkoff, Jorge A. Piedrahita · 2018 · Animal Reproduction
  92. Functional genomics of psychiatric disease risk using genome engineering
    Meilín Fernández García, Samuel K. Powell, Elizabeth A. LaMarca, Michael B. Fernando, Sophie Cohen, Gang Fang, Schahram Akbarian, Kristen Brennand · 2021 · Elsevier eBooks
  93. Genome Variation, the Epigenome and Cellular Phenotypes
    Martina Baumann, Gerald Klanert, Sabine Vcelar, Marcus Weinguny, Nicolas Marx, Nicole Borth · 2019
  94. Predicting the effect of CRISPR-Cas9-based epigenome editing
    Sanjit Singh Batra, Alan Cabrera, Jeffrey P. Spence, Jacob Goell, Selvalakshmi Selvaraj Anand, Isaac B. Hilton, Yun S. Song · 2024 · eLife
  95. Epigenome editing strategies: technological progress and in vivo applications
    Sumiyo Morita, Takuro Horii, Izuho Hatada · 2026 · BMC Methods
  96. Lactate metabolism and lactylation in female reproductive diseases: From metabolic rewiring to biomarkers and translational therapeutics
    Jiajun Qiao, Yue Xiao, Yi Cheng, Weihai Xu, Jing Shu, Shishi Li · 2026 · Clinical and Translational Medicine
  97. Epigenetic Modification of fruitless in the Protocerebrum Influences Male Drosophila Courtship Behaviour
    You Chen Roy Quah, Daiqin Li · 2022 · Springer eBooks
  98. DNA Replication - Epigenetic Mechanisms and Gene Therapy Applications
    Ziyad S. Haidar · 2023 · IntechOpen eBooks
  99. Perspective Chapter: Epigenetic Therapy – The Future Treatment for Cancer
    Surya Chandra Rao Thumu, Shobha Rani Papanna, Sundru Manjulata Devi · 2023 · IntechOpen eBooks
  100. Plant Epigenetic Editing to Analyze the Function of Histone Modifications in Gene-Specific Regulation
    Vicky Oberkofler, Isabel Bäurle · 2024 · Methods in molecular biology