Soluble amyloid precursor protein-α modulates β-secretase activity and amyloid-β generation

Cited by (195)

Items 101–195 of 195

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    Kelly Ceyzériat, Aurélien M. Badina, Laurene Abjean, Léa Meyer, Farha Bouteldja, Marta Bałkota, Quentin Amossé, Oriane Prudhomme, Ryan J. Middleton, Guo-Jun Liu et al. · 2025 · Journal of Neuroinflammation
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  17. Specific antibody binding to the APP672–699 region shifts APP processing from α- to β-cleavage
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    Florence Haut, Elentina K. Argyrousi, Ottavio Arancio · 2023 · International Journal of Molecular Sciences
  19. Human Umbilical Cord Blood Serum–derived α-Secretase
    Ahsan Habib, Huayan Hou, Takashi Mori, Jun Tian, Jin Zeng, Shengnuo Fan, Brian N. Giunta, Paul R. Sanberg, Darrell R. Sawmiller, Jun Tan · 2018 · Cell Transplantation
  20. Regressive Autism Spectrum Disorder: High Levels of Total Secreted Amyloid Precursor Protein and Secreted Amyloid Precursor Protein-α in Plasma
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  22. The Role of Thyroid Function in Alzheimer’s Disease
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    Jesus J. Campagna, K. Vadivel, B. Jagodzinska, Michael Jun, Tina V. Bilousova, P. Spilman, V. John · 2018 · Journal of Molecular Biology
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  32. Human Cord Blood Serum-Derived APP α-Secretase Cleavage Activity is Mediated by C1 Complement
    Ahsan Habib, Darrell R. Sawmiller, Huayan Hou, Manasa Kanithi, Jun Tian, Zeng Jin, Dan Zi, Zhixu He, Paul R. Sanberg, Jun Tan · 2018 · Cell Transplantation
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  34. Different Expression Patterns of Amyloid-β Protein Precursor Secretases in Human and Mouse Hippocampal Neurons: A Potential Contribution to Species Differences in Neuronal Susceptibility to Amyloid-β Pathogenesis
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  35. The Amyloid Precursor Protein: More than Just Amyloid- Beta
    Stefan D. Jevtic, John Provias · 2019 · Journal of Neurology and Experimental Neuroscience
  36. HIV-Associated Insults Modulate ADAM10 and Its Regulator Sirtuin1 in an NMDA Receptor-Dependent Manner
    Claudia López Lloreda, Sarah Chowdhury, Shivesh Ghura, Elena Alvarez-Periel, Kelly L. Jordan‐Sciutto · 2022 · Cells
  37. Cerebrovascular protective functions of amyloid precursor protein: Progress and therapeutic prospects
    Zvonimir S. Katušić, Livius V. d’Uscio, Tongrong He · 2025 · Pharmacology & Therapeutics
  38. The Effect of TCM-Induced HAMP on Key Enzymes in the Hydrolysis of AD Model Cells
    Xianhui Dong, Dongxue Ma, Tian-Ci Zhang, He Xiao-Ping, Xu Li-Jun, Yalei Liu, Hao Li, Weijuan Gao · 2021 · Neurochemical Research
  39. Aniracetam: An Evidence-Based Model for Preventing the Accumulation of Amyloid-β Plaques in Alzheimer’s Disease
    Robert W.B. Love · 2024 · Journal of Alzheimer s Disease
  40. A Novel scFv Anti-Aβ Antibody Reduces Pathological Impairments in APP/PS1 Transgenic Mice via Modulation of Inflammatory Cytokines and Aβ-related Enzymes
    Meng-Ming Hu, Jun Zhang, Junting Yang, Yue Cao, Jin‐Shun Qi · 2018 · Journal of Molecular Neuroscience
  41. A short peptide from sAPPα binding to BACE1-APP action site rescues Alzheimer-like pathology
    Xia Lai, Jie Hu, He Liu, Ling Lan, Yan Long, Xia Gao, Juan Deng · 2021 · Neuroscience Letters
  42. Blood-based therapies to combat neurodegenerative diseases
    Lee Jy, Mervyn Chen Xi Lim, Rhun Yian Koh, Min Tze Tsen, Soi Moi Chye · 2024 · Metabolic Brain Disease
  43. Tyrosine kinase receptor B isoforms alter APP and BACE1 endogenous levels independently of BDNF
    Sara Ansaloni, Brian Chun Lok Leung, Aditi Dubey, Aleister J. Saunders · 2012 · Advances in Alzheimer s Disease
  44. Stem Cell Approaches for Treatment of Neurodegenerative Diseases
    Saurabh Anand · 2014 · Clinical Pharmacology & Biopharmaceutics
  45. The US9-Derived Protein gPTB9TM Modulates APP Processing Without Targeting Secretase Activities
    Renato Brandimarti, Elena Irollo, Olimpia Meucci · 2022 · Molecular Neurobiology
  46. Novel social stimulation ameliorates memory deficit in Alzheimer's disease model through activating α-secretase
    Qiaoyun Ren, Susu Wang, Junru Li, Kun Cao, Mei Zhuang, Miao Wu, Junhua Geng, Zhengping Jia, Wei Xie, An Liu · 2024 · Journal of Neuroscience
  47. RAGE-Mediated Effects of Formaldehyde in Alzheimer’s Disease
    Ilya G. Mikhailov, Milana S. Mikhailova, Аnton N. Shuvaev, Yana V. Gorina, Оlga S. Belozor · 2025 · Biochemistry (Moscow)
  48. Temporo-spatial cellular atlas of the regenerating alveolar niche in idiopathic pulmonary fibrosis
    Praveen Nilendra Weeratunga, Bethany Hunter, Martin J. Sergeant, Joshua A. Bull, Colin Clelland, Laura Denney, Chaitanya Vuppusetty, Rachel A. Burgoyne, Jeongmin Woo, Tian Hu et al. · 2024 · medRxiv
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    Ryan Douglas Hallam, Gregory Foran, Natasha K. Fletcher, Rebecca E. K. MacPherson, Aleksandar Necakov · 2026 · American Journal of Physiology-Cell Physiology
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  66. Additional file 5 of Dysregulated expression of miR-140 and miR-122 compromised microglial chemotaxis and led to reduced restriction of AD pathology
    Chao Song, Li, Shufang, Mai, Yingren, Li, Linpeng, Guoku Dai, Zhou, Yuan, Xiaosheng Liang, Olivia Meilan Zou, Wang, Ya, Libing Zhou et al. · 2024 · Figshare
  67. Additional file 3 of Dysregulated expression of miR-140 and miR-122 compromised microglial chemotaxis and led to reduced restriction of AD pathology
    Chao Song, Li, Shufang, Mai, Yingren, Li, Linpeng, Guoku Dai, Zhou, Yuan, Xiaosheng Liang, Olivia Meilan Zou, Wang, Ya, Libing Zhou et al. · 2024 · Figshare
  68. Additional file 1 of Dysregulated expression of miR-140 and miR-122 compromised microglial chemotaxis and led to reduced restriction of AD pathology
    Chao Song, Li, Shufang, Mai, Yingren, Li, Linpeng, Guoku Dai, Zhou, Yuan, Xiaosheng Liang, Olivia Meilan Zou, Wang, Ya, Zhou, Libing et al. · 2024 · Figshare
  69. Additional file 4 of Dysregulated expression of miR-140 and miR-122 compromised microglial chemotaxis and led to reduced restriction of AD pathology
    Chao Song, Li, Shufang, Mai, Yingren, Li, Linpeng, Guoku Dai, Zhou, Yuan, Xiaosheng Liang, Olivia Meilan Zou, Wang, Ya, Libing Zhou et al. · 2024 · Figshare
  70. Additional file 2 of Dysregulated expression of miR-140 and miR-122 compromised microglial chemotaxis and led to reduced restriction of AD pathology
    Chao Song, Li, Shufang, Mai, Yingren, Li, Linpeng, Guoku Dai, Zhou, Yuan, Xiaosheng Liang, Olivia Meilan Zou, Wang, Ya, Zhou, Libing et al. · 2024 · Figshare
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  73. Implication des métabolites de l'APP dans les troubles mnésiques précoces chez la souris TgCRND8, un modèle de la maladie d'Alzheimer
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  74. Etude d’une cible thérapeutique pour la maladie d’Alzheimer et mise au point de nouveaux modèles cellulaires de criblage
    Emilie Dorard · 2016 · theses.fr (ABES)
  75. Intérêts des récepteurs 5-HT4 dans la pathologie Alzmeimer : étude préclinique comportementale et électrophysiologie sur tranche d'hippocampe de souris
    Pierre Lecouflet · 2018 · theses.fr (ABES)
  76. Molecular mechanisms of action of MT-MMPs involved in the pathogenesis of Alzheimer’s disease
    Laura García‐González · 2020 · theses.fr (ABES)
  77. Impact des pesticides sur l'agrégation des amyloïdes dans différents modèles de maladies neurodégénératives
    Pierre‐André Lafon · 2019 · theses.fr (ABES)
  78. MT5-MMP promotes neuroinflammation, pathogenic processing of amyloid precursor protein and synaptic dysfunction at early stages in an Alzheimer's disease model
    Dominika Piłat · 2021 · theses.fr (ABES)
  79. Influences biochimiques, anatomiques et cognitives de la troncation exopeptidasique N-terminale du peptide Aβ
    Audrey Valverde · 2020 · theses.fr (ABES)
  80. Unraveling the physiopathological actions of the newly discovered Aη peptides in the brain
    Maria Mensch · 2020 · theses.fr (ABES)
  81. Investigating the physiological function of the amyloid precursor protein in Drosophila melanogaster
    Eirini Kesisoglou · 2020 · theses.fr (ABES)
  82. Early memory deficits and extensive brain network disorganization in the AppNL-F/MAPT double knock-in mouse model of familial Alzheimer's disease
    Christopher Borcuk · 2021 · theses.fr (ABES)
  83. Contribution à l'étude des facteurs de risque pour la maladie d'Alzheimer : analyse de candidats identifiés par étude d'association pangénomique ou GWAS
    Charlotte Bauer · 2023 · theses.fr (ABES)
  84. The light at the end of the tunnel : study of early-stage brain dynamics alterations in Alzheimer’s disease and beneficial effects of light stimulation in the AppNL-F/MAPT mouse model
    Matthieu Aguilera · 2024 · theses.fr (ABES)
  85. A Retrospective CDSS Analysis to Compare Standardized and Non-Standardized Treatment for Central Sensitization Using Systemic Manual Therapy
    Adi Halili, Jessica Mischler · 2026 · Journal of Physical Medicine and Rehabilitation
  86. Second Section: A single domain antibody detects and neutralises toxic Aβ42 oligomers in the Alzheimer’s disease CSF
    Liliana Napolitano · 2026 · Firenze University Press eBooks
  87. References
    Liliana Napolitano · 2026 · Firenze University Press eBooks
  88. Discussion
    Liliana Napolitano · 2026 · Firenze University Press eBooks
  89. Third Section: Design of a dimeric-nanobody specific for Aβ42 oligomers: the Dimeric-DesAb-O
    Liliana Napolitano · 2026 · Firenze University Press eBooks
  90. A multidisciplinary approach for the early diagnosis of Alzheimer’s disease and potential therapeutic applications
    Liliana Napolitano · 2026 · Firenze University Press eBooks
  91. Material and Methods
    Liliana Napolitano · 2026 · Firenze University Press eBooks
  92. First Section: Putative CSF biomarkers of Alzheimer’s disease based on the novel concept of generic protein misfolding and proteotoxicity: the PRAMA cohort
    Liliana Napolitano · 2026 · Firenze University Press eBooks
  93. Introduction
    Liliana Napolitano · 2026 · Firenze University Press eBooks
  94. Conclusion and Future Perspectives
    Liliana Napolitano · 2026 · Firenze University Press eBooks
  95. Ruscus aculeatus Extract Inhibits Amyloid Beta Production and Upregulates the Active form of ADAM10 in Human Neural Progenitor Cells
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