Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells
Mae, Shin-Ichi, Shono, Akemi, Shiota, Fumihiko, Yasuno, Tetsuhiko, Kajiwara, Masatoshi, Gotoda-Nishimura, Nanaka, Arai, Sayaka, Sato-Otubo, Aiko +9 more·2013·Nature Communications
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- Current Bioengineering Methods for Whole Kidney RegenerationShuichiro Yamanaka, Takashi Yokoo · 2015 · Stem Cells International
- Tubular organotypic culture model of human kidneyDae Young Jun, Sook Young Kim, Joon Chae Na, Hyung Ho Lee, Jeehoon Kim, Young Eun Yoon, Sung Joon Hong, Woong Kyu Han · 2018 · PLoS ONE
- Recreating kidney progenitors from pluripotent cellsMinoru Takasato, Barbara Maier, Melissa Helen Little · 2013 · Pediatric Nephrology
- Renal lineage cells as a source for renal regenerationOren Pleniceanu, Dorit Omer, Orit Harari‐Steinberg, Benjamin Dekel · 2017 · Pediatric Research
- Multidisciplinary approaches for elucidating genetics and molecular pathogenesis of urinary tract malformationsKamal Khan, Dina F. Ahram, Yangfan P. Liu, Rik Westland, Rosemary V. Sampogna, Nicholas Katsanis, Erica E. Davis, Simone Sanna‐Cherchi · 2021 · Kidney International
- Hand2 inhibits kidney specification while promoting vein formation within the posterior mesodermElliot A. Perens, Zayra Viviana Garavito-Aguilar, Gina P. Guio-Vega, Karen T Peña, Yocheved L. Schindler, Deborah L. Yelon · 2016 · eLife
- Growing a new human kidneyAdrian S. Woolf · 2019 · Kidney International
- Direct Isolation and Characterization of Human Nephron ProgenitorsStefano Da Sacco, Matthew Edward Thornton, Astgik Petrosyan, Maria Lavarreda-Pearce, Sargis Sedrakyan, Brendan H. Grubbs, Roger E. De Filippo, Laura Perin · 2016 · Stem Cells Translational Medicine
- iPSC technology-based regenerative medicine for kidney diseasesKenji Osafune · 2021 · Clinical and Experimental Nephrology
- The Role of Sequential BMP Signaling in Directing Human Embryonic Stem Cells to Bipotential Gonadal CellsKirsi Sepponen, Karolina Lundin, Katri Knuus, Pia Väyrynen, Taneli Raivio, Juha S. Tapanainen, Timo Tuuri · 2017 · The Journal of Clinical Endocrinology & Metabolism
- Abatacept and Glomerular Diseases: The Open Road for the Second Signal as a New Target is Settled DownHernán Trimarchi · 2015 · Recent Patents on Endocrine Metabolic & Immune Drug Discovery
- Engineered renal tissue as a potential platform for pharmacokinetic and nephrotoxicity testingJamie A. Davies · 2013 · Drug Discovery Today
- Analysis of the Role of Homology Arms in Gene-Targeting Vectors in Human CellsAyako Ishii, Aya Kurosawa, Shinta Saito, Noritaka Adachi · 2014 · PLoS ONE
- Kidney structures differentiated from stem cellsBenjamin D. Humphreys · 2013 · Nature Cell Biology
- Adult stem cells as a tool for kidney regenerationEtsu Suzuki · 2016 · World Journal of Nephrology
- The nephric mesenchyme lineage of intermediate mesoderm is derived from Tbx6-expressing derivatives of neuro-mesodermal progenitors via BMP-dependent Osr1 functionShinichi Hayashi, Hitomi Suzuki, Tatsuya Takemoto · 2021 · Developmental Biology
- Human pluripotent stem cell–derived erythropoietin-producing cells ameliorate renal anemia in miceHirofumi Hitomi, Tomoko Kasahara, Naoko Katagiri, Azusa Hoshina, Shin-Ichi Mae, Maki Kotaka, Takafumi Toyohara, Asadur Rahman, Daisuke Nakano, Akira Niwa et al. · 2017 · Science Translational Medicine
- Combining Kidney Organoids and Genome Editing Technologies for a Better Understanding of Physiopathological Mechanisms of Renal Diseases: State of the ArtClara Steichen, Sébastien Giraud, Thierry Hauet · 2020 · Frontiers in Medicine
- Insights to Heart Development and Cardiac Disease Models Using Pluripotent Stem Cell Derived 3D OrganoidsJeremy Kah Sheng Pang, Beatrice Xuan Ho, Woon‐Khiong Chan, Boon-Seng Soh · 2021 · Frontiers in Cell and Developmental Biology
- Production of kidney organoids arranged around single ureteric bud trees, and containing endogenous blood vessels, solely from embryonic stem cellsAnwar Azad Palakkan, Julia Tarnick, Martin Waterfall, May Sallam, Fokion Glykofrydis, Mona Elhendawi, Jamie A. Davies · 2022 · Scientific Reports
- Engineering kidney cells: reprogramming and directed differentiation to renal tissuesMichael M. Kaminski, Jelena Tošić, Roman Pichler, Sebastian J. Arnold, Soeren S. Lienkamp · 2017 · Cell and Tissue Research
- Organoids of liver diseases: From bench to bedsideLijun Wu, Ziyan Chen, Yi Wang, Jungang Zhao, Xiaozai Xie, Gang Chen · 2019 · World Journal of Gastroenterology
- Selective induction of human renal interstitial progenitor-like cell lineages from iPSCs reveals development of mesangial and EPO-producing cellsHiraku Tsujimoto, Azusa Hoshina, Shin-Ichi Mae, Toshikazu Araoka, Wang Changting, Yoshihiro Ijiri, May Nakajima‐Koyama, Satoko Sakurai, Kazusa Okita, Ken Mizuta et al. · 2024 · Cell Reports
- Embryonic Stem Cells-loaded Gelatin Microcryogels Slow Progression of Chronic Kidney DiseaseXiaodong Geng, Wei Zheng, Congmei Wu, Shuqiang Wang, Quan Hong, Guangyan Cai, Xiangmei Chen, Di Wu · 2016 · Chinese Medical Journal
- Parallel generation of easily selectable multiple nephronal cell types from human pluripotent stem cellsKrithika Hariharan, Harald Stachelscheid, Bella Rossbach, Su-Jun Oh, Nancy Mah, Kai Martin Schmidt-Ott, Armin Kurtz, Petra Reinke · 2018 · Cellular and Molecular Life Sciences
- Induced Pluripotent Stem Cell Generation from Blood Cells Using Sendai Virus and CentrifugationYeri Alice Rim, Yoojun Nam, Ji Hyeon Ju · 2016 · Journal of Visualized Experiments
- Adult stem-like cells in kidneyKeiichi Hishikawa · 2015 · World Journal of Stem Cells
- Generating kidney tissue from pluripotent stem cellsMelissa Helen Little · 2016 · Cell Death Discovery
- Potential use of stem or progenitor cells for kidney regenerationLuigi Biancone, Giovanni Camussi · 2013 · Nature Reviews Nephrology
- Using stem and progenitor cells to recapitulate kidney development and restore renal functionPatricia A. Murray, Adrian S. Woolf · 2014 · Current Opinion in Organ Transplantation
- Generating a self-organizing kidney from pluripotent cellsMelissa Helen Little, Minoru Takasato · 2015 · Current Opinion in Organ Transplantation
- Renal Injury Repair: How About the Role of Stem CellsJian-Si Li, Bing Li · 2019 · Advances in experimental medicine and biology
- Differentiation of human kidney organoids from pluripotent stem cellsNelly M. Cruz, Benjamin Freedman · 2019 · Methods in cell biology
- Autologous Cells for Kidney BioengineeringBettina Wilm, Riccardo Tamburrini, Giuseppe Orlando, Patricia A. Murray · 2016 · Current Transplantation Reports
- Kidney transplantation, bioengineering and regeneration: an originally immunology-based discipline destined to transition towards ad hoc organ manufacturing and repairJeffrey D. Rogers, Ravi Katari, Sheyna Gifford, Riccardo Tamburrini, Lauren Edgar, Marcia R. Voigt, Sean V. Murphy, Daniel A. Igel, Sarah E. Mancone, Tyler E. Callese et al. · 2015 · Expert Review of Clinical Immunology
- Regeneration of cervical reserve cell-like cells from human induced pluripotent stem cells (iPSCs): A new approach to finding targets for cervical cancer stem cell treatmentMasakazu Sato, Kei Kawana, Katsuyuki Adachi, Asaha Fujimoto, Mitsuyo Yoshida, Hiroe Nakamura, Haruka Nishida, Tomoko Inoue, Ayumi Taguchi, Juri Ogishima et al. · 2017 · Oncotarget
- From organoids to transplantable artificial kidneysHidekazu Naganuma, Ryuichi Nishinakamura · 2019 · Transplant International
- Adrenergic receptor agonists induce the differentiation of pluripotent stem cell-derived hepatoblasts into hepatocyte-like cellsMaki Kotaka, Tarō Toyoda, Katsutaro Yasuda, Yuko Kitano, Chihiro Okada, Akira Ohta, Akira Watanabe, Motonari Uesugi, Kenji Osafune · 2017 · Scientific Reports
- Kidney organoids: Research in developmental biology and emerging applicationsTatsuya Shimizu, Kunihiro Yamagata, Kenji Osafune · 2021 · Development Growth & Differentiation
- Kindling the KidneySusan E. Quaggin · 2016 · New England Journal of Medicine
- Differentiating Induced Pluripotent Stem Cells into Renal Cells: A New Approach to Treat Kidney DiseasesPatrícia de Carvalho Ribeiro, Lucas Felipe de Oliveira, Mário Abbud‐Filho, Heloisa Cristina Caldas · 2020 · Stem Cells International
- Directed Differentiation of Pluripotent Stem Cells into KidneyRyuji Morizane, Albert Q. Lam · 2015 · Biomarker Insights
- Anephrogenic phenotype induced by SALL1 gene knockout in pigsMasahito Watanabe, Kazuaki Nakano, Ayuko Uchikura, Hitomi Matsunari, Sayaka Yashima, Kazuhiro Umeyama, Shuko Takayanagi, Tetsushi Sakuma, Takashi Yamamoto, Sumiyo Morita et al. · 2019 · Scientific Reports
- Human reconstructed kidney modelsSeiji Kishi, Takuya Matsumoto, Takaharu Ichimura, Craig R. Brooks · 2021 · In Vitro Cellular & Developmental Biology - Animal
- Growth Factor Regulation in the Nephrogenic Zone of the Developing KidneyLeif H. Oxburgh, Sree Deepthi Muthukrishnan, Aaron Clifford Brown · 2017 · Results and problems in cell differentiation
- Potential Strategies for Kidney Regeneration With Stem Cells: An OverviewKenji Tsuji, Shinji Kitamura, Jun Wada · 2022 · Frontiers in Cell and Developmental Biology
- Gene editing of stem cells for kidney disease modelling and therapeutic interventionRicky WK Lau, Bo Wang, Sharon D. Ricardo · 2018 · Nephrology
- Assessing kidney development and disease using kidney organoids and CRISPR engineeringWajima Safi, Andrés Marco, Daniel Moya, Patricia Prado, Elena Garreta, Núria Montserrat · 2022 · Frontiers in Cell and Developmental Biology
- In vitro methods to ensure absence of residual undifferentiated human induced pluripotent stem cells intermingled in induced nephron progenitor cellsHiraku Tsujimoto, Naoko Katagiri, Yoshihiro Ijiri, Ben Sasaki, Yoshifumi Kobayashi, Akira Mima, Makoto Ryosaka, Kenichiro Furuyama, Yoshiya Kawaguchi, Kenji Osafune · 2022 · PLoS ONE
- How to grow a kidney: patient-specific kidney organoids come of ageKai Martin Schmidt-Ott · 2016 · Nephrology Dialysis Transplantation
- Guided Differentiation of Mature Kidney Podocytes from Human Induced Pluripotent Stem Cells Under Chemically Defined ConditionsMorgan A. Burt, Rohan Bhattachaya, Arinze Emmanuel Okafor, Samira Musah · 2020 · Journal of Visualized Experiments
- Current strategies on kidney regeneration using tissue engineering approaches: a systematic reviewParham Torabinavid, Mohammad Hossein Khosropanah, Ashkan Azimzadeh, A.M. Kajbafzadeh · 2025 · BMC Nephrology
- Is regenerative medicine a new hope for kidney replacement?Maciej S. Nowacki, Tomasz Kloskowski, Marta Pokrywczyńska, Łukasz Nazarewski, Arkadiusz Jundziłł, Katarzyna Pietkun, Dominik Janusz Tyloch, Marta Rasmus, Karolina Warda, Samy L. Habib et al. · 2014 · Journal of Artificial Organs
- Kidney regeneration from human induced pluripotent stem cellsShin-Ichi Mae, Kenji Osafune · 2015 · Current Opinion in Organ Transplantation
- Assembling Kidney Tissues from Cells: The Long Road from Organoids to OrgansKrithika Hariharan, Armin Kurtz, Kai Martin Schmidt-Ott · 2015 · Frontiers in Cell and Developmental Biology
- RETRACTED ARTICLE: Transplantation of Mouse Induced Pluripotent Stem Cell-Derived Podocytes in a Mouse Model of Membranous Nephropathy Attenuates ProteinuriaAmin Ahmadi, Reza Moghadasali, Vahid Ezzatizadeh, Zeinab Taghizadeh, Seyed Mahdi Nassiri, Mohammad Hassan Asghari, Mehdi Alikhani, Fatemeh Hadi, Reza Rahbarghazi, Reza Salman Yazdi et al. · 2019 · Scientific Reports · Retracted
- Regenerating the nephron with human pluripotent stem cellsAlbert Q. Lam, Joseph Vincent Bonventre · 2015 · Current Opinion in Organ Transplantation
- Accelerated protocol for the differentiation of podocytes from human pluripotent stem cellsJulie Bejoy, Eddie S. Qian, Lauren Elizabeth Woodard · 2021 · STAR Protocols
- Tissue-Engineering Approaches to Restore Kidney FunctionRavi Katari, Lauren Edgar, Theresa Wong, Angela Boey, Sarah E. Mancone, Daniel A. Igel, Tyler E. Callese, Marcia R. Voigt, Riccardo Tamburrini, João Paulo Zambon et al. · 2015 · Current Diabetes Reports
- Induction of nephron progenitors and glomeruli from human pluripotent stem cellsRyuichi Nishinakamura, Sazia Sharmin, Atsuhiro Taguchi · 2016 · Pediatric Nephrology
- Defense of COVID-19 by Human OrganoidsTing Lv, Fanlu Meng, Meng Yu, Haihui Huang, Xinhua Lin, Bing Tian Zhao · 2021 · Phenomics
- Urological cancer organoids, patients' avatars for precision medicine: past, present and futureHaotian Chen, Wentao Zhang, Niraj Maskey, Fuhan Yang, Zongtai Zheng, Cheng Li, Ruiliang Wang, Pengfei Wu, Shiyu Mao, Junfeng Zhang et al. · 2022 · Cell & Bioscience
- Studying Kidney Disease Using Tissue and Genome Engineering in Human Pluripotent Stem CellsElena Garreta, Federico Gonzãlez, Núria Montserrat · 2017 · The Nephron journals/Nephron journals
- Nephron generation in kidney cortices through injection of pretreated mesenchymal stem cell-differentiated tubular epithelial cellsToshihiko Machiguchi, Tatsuo Nakamura · 2019 · Biochemical and Biophysical Research Communications
- The bioengineered kidneyLeif H. Oxburgh, Thomas J. Carroll · 2016 · Current Opinion in Nephrology & Hypertension
- Regenerative Medicine, Disease Modeling, and Drug Discovery in Human Pluripotent Stem Cell-derived Kidney Tissue.Navin R. Gupta, Koichiro Susa, Ryuji Morizane · 2017 · PubMed
- Hydrogel and nanoparticle carriers for kidney disease therapy: trends and recent advancementsXu‐rui Gu, Zhen Liu, Yifan Tai, Lingyun Zhou, Kun Liu, Deling Kong, Adam C. Midgley, Xiao‐cong Zuo · 2022 · Progress in Biomedical Engineering
- Scaffolds from Surgically Removed Kidneys as a Potential Source of Organ TransplantationMarek Karczewski, Tomasz Małkiewicz · 2015 · BioMed Research International
- Scaffold-Free BiofabricationAna Raquel Verissimo, Koichi Nakayama · 2017 · Springer eBooks
- Pluripotent Stem Cells to Rebuild a Kidney: The Lymph Node as a Possible Developmental NicheMaria Giovanna Francipane, Eric Lagasse · 2016 · Cell Transplantation
- The centrosomal protein 83 (CEP83) regulates human pluripotent stem cell differentiation toward the kidney lineageFatma Mansour, Christian Hinze, Narasimha Swamy Telugu, Jelena Kresoja‐Rakic, Iman B. Shaheed, Christian Mosimann, Sebastian Diecke, Kai Martin Schmidt-Ott · 2022 · eLife
- Tissue in Cube: In Vitro 3D Culturing Platform with Hybrid Gel Cubes for Multidirectional ObservationsMasaya HAGIWARA, Tomohiro Kawahara, Rina Nobata · 2016 · Advanced Healthcare Materials
- Significance of dopamine D1 receptor signalling for steroidogenic differentiation of human induced pluripotent stem cellsKoji Matsuo, Masakatsu Sone, Kyoko Honda-Kohmo, Takafumi Toyohara, Takuhiro Sonoyama, Daisuke Taura, Katsutoshi Kojima, Yorihide Fukuda, Youichi Ohno, Mayumi Inoue et al. · 2017 · Scientific Reports
- Priming the renal progenitor cellDiana M. Iglesias, Murielle M. Akpa, Paul Goodyer · 2014 · Pediatric Nephrology
- Three-dimensional culture in a bioengineered matrix and somatic cell complementation to improve growth and survival of bovine preantral folliclesJuliana I. Candelaria, Ramon César Botigelli, Carly Guiltinan, Ariella Shikanov, Anna Carolina Denicol · 2025 · Journal of Assisted Reproduction and Genetics
- Perspectives of gene combinations in phenotype presentationShihori Tanabe · 2013 · World Journal of Stem Cells
- Great potential of renal progenitor cells in kidney: From the development to clinicMaryam Bahrami, Shahram Darabi, Navid Ahmady Roozbahany, Hojjat‐Allah Abbaszadeh, Reza Moghadasali · 2023 · Experimental Cell Research
- Cell Therapy for Kidney Injury: Different Options and Mechanisms - Kidney Progenitor CellsKenji Osafune · 2014 · Nephron Experimental Nephrology
- Experimental renal progenitor cells: Repairing and recreating kidneys?Paul J. D. Winyard, Karen L. Price · 2013 · Pediatric Nephrology
- Current State of Renal Regenerative Therapies.A. S. Shankar, E. Hoorn, J. Gribnau, C. Baan, M. Hoogduijn · 2019 · Transplantation
- Human RFX6 regulates endoderm patterning at the primitive gut tube stageToshihiro Nakamura, Junji Fujikura, Ryo Ito, Yamato Keidai, Nobuya Inagaki · 2023 · PNAS Nexus
- Reprogramming somatic cells to a kidney fate.Minoru Takasato, J. Vanslambrouck, M. Little · 2014 · Seminars in Nephrology
- Kidney Regeneration with Stem Cells: An OverviewTakashi Yokoo · 2014 · Nephron Experimental Nephrology
- Challenges for Production of Human Transplantable Organ GraftsEiji Kobayashi · 2016 · Cell Medicine
- Obstacles in Renal Regenerative Medicine: Metabolic and Epigenetic Parallels Between Cellular Reprogramming and Kidney Cancer OncogenesisZsuzsanna Lichner, Fabrice Mac‐Way, George M. Yousef · 2017 · European Urology Focus
- Human induced pluripotent stem cell-derived kidney organoids toward clinical implementationsElena Garreta, Zarina Nauryzgaliyeva, Núria Montserrat · 2021 · Current Opinion in Biomedical Engineering
- Engineered kidneys: principles, progress, and prospectsJamie A. Davies, C‐Hong Chang, Melanie L. Lawrence, Christopher G. Mills, John J. Mullins · 2014 · Advances in Regenerative Biology
- Review on kidney diseases: types, treatment and potential of stem cell therapyJaspreet Singh, Sanjeev Singh · 2023 · Renal Replacement Therapy
- MicroRNA-498 Inhibition Enhances the Differentiation of Human Adipose-Derived Mesenchymal Stem Cells into Podocyte-Like CellsLina Zhang, Kanghua Li, Xi Yan, Xiaolei Liang, Shihua Wang, Qin Han, Robert Chunhua Zhao · 2015 · Stem Cells and Development
- Les organoïdes rénauxClara Steichen, Sébastien Giraud, Thierry Hauet · 2019 · médecine/sciences
- The Race for Regeneration: Pluripotent-Stem-Cell-Derived 3D Kidney StructuresValerie Gouon–Evans · 2014 · Cell stem cell
- Cellular interactions via conditioned media induce in vivo nephron generation from tubular epithelial cells or mesenchymal stem cellsToshihiko Machiguchi, Tatsuo Nakamura · 2013 · Biochemical and Biophysical Research Communications
- Differentiation and isolation of iPSC-derived remodeling ductal plate-like cells by use of an AQP1-GFP reporter human iPSC lineSatoshi Matsui, Miyuki Ochiai, Katsutaro Yasuda, Shin-Ichi Mae, Maki Kotaka, Tarō Toyoda, Takuya Yamamoto, Kenji Osafune · 2019 · Stem Cell Research
- Mastering Organoid Growth: A Complete Guide to Overcoming Methodological ChallengesChunbao Jiao, Omer Faruk Karakaya, Neda Dadgar, Chase J. Wehrle, Zahra Massoud, Hanna Hong, Robert L. Fairchild, Nic D. Leipzig, Federico Aucejo, Wen Wee Ma et al. · 2026 · MedComm
- Reforming the Kidney Starting from a Single-Cell SuspensionChristodoulos Xinaris, Takashi Yokoo · 2014 · Nephron Experimental Nephrology
- Modeling renal progenitors – defining the nicheShunsuke Tanigawa, Alan O. Perantoni · 2016 · Differentiation
- Reconstitution of the kidney glomerular capillary wallTitilola D. Kalejaiye, Jordan A. Holmes, Rohan Bhattacharya, Samira Musah · 2021 · Elsevier eBooks
- Modelling Cellular Interactions and Dynamics During Kidney MorphogenesisBlake Cook, Alexander N. Combes, Melissa Helen Little, James M. Osborne · 2021 · Bulletin of Mathematical Biology
- Direct transcriptional reprogramming to nephron progenitorsJessica May Vanslambrouck, Melissa Helen Little · 2015 · Current Opinion in Genetics & Development
- Making new kidneysOded Volovelsky, Raphael Kopan · 2016 · Current Opinion in Organ Transplantation