Activation pathway of Src kinase reveals intermediate states as targets for drug design

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Items 101–200 of 338

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14. Structural Basis of Protein Kinase R Autophosphorylation
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18. Markov models for the elucidation of allosteric regulation
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26. Heat dissipation guides activation in signaling proteins
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31. HRD Motif as the Central Hub of the Signaling Network for Activation Loop Autophosphorylation in Abl Kinase
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38. Global and Local Conformation of Human IgG Antibody Variants Rationalizes Loss of Thermodynamic Stability
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44. Autophosphorylation activates c-Src kinase through global structural rearrangements
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46. Identification of druggable kinase target conformations using Markov model metastable states analysis of apo-Abl
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47. Automatic Selection of Order Parameters in the Analysis of Large Scale Molecular Dynamics Simulations
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48. Computationally Discovered Potentiating Role of Glycans on NMDA Receptors
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51. A switch in nucleotide affinity governs activation of the Src and Tec family kinases
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