Enhanced synapse remodelling as a common phenotype in mouse models of autism

Cited by (152)

Items 101–152 of 152

  1. Imaging of spine synapses using super-resolution microscopy
    Yutaro Kashiwagi, Shigeo Okabe · 2021 · Anatomical Science International
  2. Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment
    Hideo Hagihara, Hirotaka Shoji, Satoko Hattori, Giovanni Sala, Yoshihiro Takamiya, Mika Tanaka, Masafumi Ihara, Mihiro Shibutani, Izuho Hatada, Kei Hori et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  3. The role of glia in the dysregulation of neuronal spinogenesis in Ube3a-dependent ASD
    Zachary Gardner, Otto Holbrook, Yuan Tian, KathrynAnn E. Odamah, Heng‐Ye Man · 2024 · Experimental Neurology
  4. Implantation of a Cranial Window for Repeated In Vivo Imaging in Awake Mice
    Ragunathan Padmashri, Kevin Tyner, Anna Dunaevsky · 2021 · Journal of Visualized Experiments
  5. Aberrant outputs of cerebellar nuclei and targeted rescue of social deficits in an autism mouse model
    Xinyu Cai, Xin‐Tai Wang, Jing-Wen Guo, Fang‐Xiao Xu, Kuang-Yi Ma, Zhaoxiang Wang, Yue Zhao, Wei Xie, Martijn Schonewille, Chris I. De Zeeuw et al. · 2024 · Protein & Cell
  6. Super-resolved 3D-STED microscopy identifies a layer-specific increase in excitatory synapses in the hippocampal CA1 region of Neuroligin-3 KO mice
    Noriko Koganezawa, Kenji Hanamura, Manuela Schwark, Dilja Krueger‐Burg, Hiroshi Kawabe · 2021 · Biochemical and Biophysical Research Communications
  7. Revealing synaptic nanostructure distribution through automatic dendritic spine segmentation and single-molecule localization microscopy
    Jiahao Zhang, Rohit M. Vaidya, Rujuta Pendharkar, Hee Jung Chung, Paul R. Selvin · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  8. Differential Development of Dendritic Spines in Striatal Projection Neurons of Direct and Indirect Pathways in the Caudoputamen and Nucleus Accumbens
    Hsiao‐Ying Kuo, Ya-Hui Yang, Shih‐Yun Chen, Tzu-Hsin Kuo, Wan-Ting Lin, FC Liu · 2023 · eNeuro
  9. Reducing Filamin A Restores Cortical Synaptic Connectivity and Early Social Communication Following Cellular Mosaicism in Autism Spectrum Disorder Pathways
    Matthew S. Binder, Iris Escobar, Youfen Xu, Aidan M. Sokolov, Longbo Zhang, Angélique Bordey · 2024 · Journal of Neuroscience
  10. Characterizing spine issues: If offers novel therapeutics to Angelman syndrome
    Xin Yang · 2020 · Developmental Neurobiology
  11. Intravital Imaging of Fluorescent Protein Expression in Mice with a Closed-Skull Traumatic Brain Injury and Cranial Window Using a Two-Photon Microscope
    Jianjun Zhong, Georgia Gunner, Nils Henninger, Dorothy P. Schafer, Daryl A. Bosco · 2023 · Journal of Visualized Experiments
  12. Altered projection-specific synaptic remodeling and its modification by oxytocin in an idiopathic autism marmoset model
    Jun Noguchi, Satoshi Watanabe, Tomofumi Oga, Risa Isoda, Keiko Nakagaki, Kazuhisa Sakai, Kayo Sumida, Kohei Hoshino, Koichi Saito, Izuru Miyawaki et al. · 2024 · Communications Biology
  13. Transcriptomic Evidence Reveals the Dysfunctional Mechanism of Synaptic Plasticity Control in ASD
    Chao Kong, Zhitong Bing, Lei Yang, Zi‐Gang Huang, Wen-Xu Wang, Celso Grebogi · 2024 · Genes
  14. Decreased Expression of Synaptophysin 1 (SYP1 Major Synaptic Vesicle Protein p38) and Contactin 6 (CNTN6/NB3) in the Cerebellar Vermis of reln Haplodeficient Mice
    Claudia Castagna, Adalberto Merighi, Laura Lossi · 2019 · Cellular and Molecular Neurobiology
  15. Impaired actin dynamics and suppression of Shank2-mediated spine enlargement in cortactin knockout mice
    Shinji Tanaka, Yasutaka Masuda, Akihiro Harada, Shigeo Okabe · 2020 · Microscopy
  16. Excessive ERK-dependent synaptic clustering drives enhanced motor learning in the MECP2 duplication syndrome mouse model of autism
    Ryan Thomas Ash, Shelly Alexandra Buffington, Jiyoung Park, Mauro Costa‐Mattioli, Huda Yahya Zoghbi, Stelios M. Smirnakis · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
  17. Induction of LTP mechanisms in dually innervated dendritic spines
    Jonathan E. Tullis, Karl Ulrich Bayer · 2024 · Scientific Reports
  18. Elimination of the extra chromosome of Dup15q syndrome iPSCs for cellular and molecular investigation
    Haruka Munezane, Keiko Imamura, Naoko Fujimoto, Akitsu Hotta, Hiroshi Yukitake, Haruhisa Inoue · 2024 · European Journal of Cell Biology
  19. RO4938581, a GABAA-α5 negative allosteric modulator rescued behavioral and EEG phenotypes of a mouse model of Dup15q syndrome
    Ryoko Nakagawa, Francesca Nani, Joerg F. Hipp, Michael Honer, Frédéric Knoflach, Rodolfo Gasser, Laurence Ozmen, Kota Tamada, Fatiha Fjeldskaar, Livia Takacs et al. · 2026 · Molecular Psychiatry
  20. Neonatal social isolation increases the proportion of the immature spines in the layer 2/3 pyramidal neurons of the somatosensory cortex
    Risa Iguchi, Shinji Tanaka, Shigeo Okabe · 2019 · Neuroscience Research
  21. In VivoObservation of Structural Changes in Neocortical Catecholaminergic Projections in Response to Drugs of Abuse
    Mai M Morimoto, Shinji Tanaka, Shunsuke Mizutani, Shinji Urata, Kazuto Kobayashi, Shigeo Okabe · 2018 · eNeuro
  22. Extracellular Matrix Muscle Arm Development Defective Protein Cooperates with the One Immunoglobulin Domain Protein To Suppress Precocious Synaptic Remodeling
    Chunhong Chen, Huiyuan Fu, Ping He, Peng Hui Yang, Haijun Tu · 2021 · ACS Chemical Neuroscience
  23. Technical Toolbox for Decoding Synaptic Complexity
    Laxmi Kumar Parajuli · 2018 · Juntendō Igaku/Juntendo igaku
  24. miR-199a functions downstream of MeCP2 in neurons of MECP2 duplication syndrome models
    Yuichi Akaba, Satoru Takahashi, Shota Adachi, Masatoshi Nishimura, Keiichiro Suzuki, Hideyuki Nakashima, Kinichi Nakashima, Ryutaro Kira, Pin Fee Chong, Yasunari Sakai et al. · 2025 · iScience
  25. Integrative Approach to Child and Adolescent Mental Health
    Seung-Pil Jung · 2017 · InTech eBooks
  26. Comparative Perspectives on the Function of Oxytocin in Fish and Mammals
    Saori Yokoi, Larry J. Young, Hideaki Takeuchi · 2022 · Springer eBooks
  27. Development and Application of Technology for Neural Circuit Visualization - Secondary Publication
    Shigeo Okabe · 2024 · JMA Journal
  28. Training Schedule Affects Operant Responding Independent of Motivation in the Neuroligin‐3 R451C Mouse Model of Autism
    Riki Dingwall, Carlos May, Jackson A. McDonald, Thomas Hill, Robyn M. Brown, Andrew John Lawrence, Anthony John Hannan, Emma L. Burrows · 2025 · Genes Brain & Behavior
  29. Imaging Synapse Formation and Remodeling In Vitro and In Vivo
    Shigeo Okabe · 2019 · Springer eBooks
  30. Dendritic spine abnormalities in a mouse model of Fragile X syndrome
    Adam Aharon · 2015 · eScholarship (California Digital Library)
  31. In Vivo Visualization of Single Axons and Synaptic Remodeling in Normal and Pathological Conditions
    Federico W. Grillo, Alison Jane Canty, Peter S. Bloomfield, Vincenzo De Paola · 2016 · Elsevier eBooks
  32. Molecular Assembly of Excitatory Synapses
    Hirohide Iwasaki, Shinji Tanaka, Shigeo Okabe · 2016 · Springer eBooks
  33. C2-P-05In vivo two-photon imaging of synapse dynamics in mouse models of autism
    Shinji Tanaka, Masaaki Isshiki, Toshihiko Kuriu, Katsuhiko Tabuchi, Toru Takumi, Shigeo Okabe · 2015 · Microscopy
  34. Visualizing inhibitory and excitatory synapse dynamics In vivo
    Kalen Berry · 2018 · DSpace@MIT (Massachusetts Institute of Technology)
  35. “Memory” in the Mammalian Brain
    Jaichandar Subramanian · 2016 · Annals of SBV
  36. The impact of the interaction between Neuroligin3 and CYFIP1 on phenotypes associated with Autism Spectrum Disorders
    Monika Śledziowska · 2020 · ORCA Online Research @Cardiff (Cardiff University)
  37. Analysis of cortical network dynamics in the behavioral state of a mouse model of autism
    Nobuhiro Nakai, Toru Takumi · 2023 · Folia Pharmacologica Japonica
  38. Neurobiological Foundations of Psychiatry: Overview
    Tadafumi Kato · 2023 · Springer eBooks
  39. Neurobiological Foundations of Psychiatry: Overview
    Tadafumi Kato · 2024 · Springer eBooks
  40. Impaired metabotropic glutamate type 5 receptor signaling in the dorsal striatum of the R451C-neuroligin 3 mouse model of Autism Spectrum Disorder
    Maria Meringolo, Martina Montanari, Simona D’Antoni, Giuseppina Martella, Ilham El Atiallah, Giulia Ponterio, Annalisa Tassone, Ingrid Reverte, Daniele Caprioli, Georgios Strimpakos et al. · 2024 · Research Square
  41. Impaired metabotropic glutamate type 5 receptor signaling in the dorsal striatum of the R451C-neuroligin 3 mouse model of Autism Spectrum Disorder
    Maria Meringolo, Martina Montanari, Simona D’Antoni, Giuseppina Martella, Ilham El Atiallah, Giulia Ponterio, Annalisa Tassone, Ingrid Reverte, Daniele Caprioli, Georgios Strimpakos et al. · 2025 · Research Square
  42. Spine nanostructure profiling of cultured neurons from mouse models reveals a schizophrenia-linked role for Ecrg4
    Yutaro Kashiwagi, Qingrui Liu, Yasuhiro Go, Ryo� Saito, Atsu Aiba, Takanobu Nakazawa, Shigeo Okabe · 2026 · eLife
  43. Spine nanostructure profiling of cultured neurons from mouse models reveals a schizophrenia-linked role for Ecrg4
    Yutaro Kashiwagi, Qingrui Liu, Yasuhiro Go, Ryo Saito, Atsu Aiba, Takanobu Nakazawa, Shigeo Okabe · 2025 · eLife
  44. Decoding Spine Nanostructure in Mental Disorders Reveals a Schizophrenia-Linked Role for Ecrg4
    Yutaro Kashiwagi, Qingrui Liu, Yasuhiro Go, Ryo Saito, Atsu Aiba, Takanobu Nakazawa, Shigeo Okabe · 2025 · eLife
  45. Shank3B deficiency disrupts GABAergic synaptic transmission in pyramidal neurons of the medial prefrontal cortex region in autism spectrum disorder
    Hang Yin, Ke Sun, Chenyang Wang, Songqiao Fan, Jiaqi Wang, Shitai He, Hui meng Lei, Shuo Pang, Jie Chen, G G Zhang · 2026 · Molecular Brain
  46. Behavioral and synaptic consequences following removal of the Il1rapl1 gene in mice, a model of intellectual disability
    Xander Houbaert · 2014 · theses.fr (ABES)
  47. Etude du développement cortical à travers la caractérisation d'un modèle murin d'autisme et l'inférence des interactions cellulaires par séquençage en cellules uniques
    Rémi Mathieu · 2022 · theses.fr (ABES)
  48. Alteration and targeting of microglia in congenital cytomegalovirus infection of the brain
    Carla Crespo-Quiles · 2022
  49. The role of transcription factor Neurod2 in cortex development and its implications in neurodevelopmental disorders
    Karen Runge · 2022 · theses.fr (ABES)
  50. Gut microbiota-derived 5-HTP penetrates the host blood–brain barrier and ameliorates autism symptoms
    Bei Li, Qianqian Yang, Min Li, Junqing He, Zhiqi Zhang, Xuchun Wan, Zihao Mo, Ruizhen Li, Shihan Li, Weirong Xu et al. · 2026 · Acta Pharmaceutica Sinica B
  51. Decoding spine nanostructure in cultured neurons derived from mouse models of mental disorder reveals a schizophrenia-linked role for Ecrg4
    Yutaro Kashiwagi, Qingrui Liu, Yasuhiro Go, Ryo Saito, Atsu Aiba, Takanobu Nakazawa, Shigeo Okabe · 2026 · eLife
  52. Decoding spine nanostructure in cultured neurons derived from mouse models of neuropsychiatric disorder reveals a schizophrenia-linked role for Ecrg4
    Yutaro Kashiwagi, Qingrui Liu, Yasuhiro Go, Ryo Saito, Atsu Aiba, Takanobu Nakazawa, Shigeo Okabe · 2026 · eLife