Enhanced synapse remodelling as a common phenotype in mouse models of autism
Isshiki, Masaaki, Tanaka, Shinji, Kuriu, Toshihiko, Tabuchi, Katsuhiko, Takumi, Toru, Okabe, Shigeo·2014·Nature Communications
Cited by (152)
Items 101–152 of 152
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- The role of glia in the dysregulation of neuronal spinogenesis in Ube3a-dependent ASDZachary Gardner, Otto Holbrook, Yuan Tian, KathrynAnn E. Odamah, Heng‐Ye Man · 2024 · Experimental Neurology
- Implantation of a Cranial Window for Repeated In Vivo Imaging in Awake MiceRagunathan Padmashri, Kevin Tyner, Anna Dunaevsky · 2021 · Journal of Visualized Experiments
- Aberrant outputs of cerebellar nuclei and targeted rescue of social deficits in an autism mouse modelXinyu Cai, Xin‐Tai Wang, Jing-Wen Guo, Fang‐Xiao Xu, Kuang-Yi Ma, Zhaoxiang Wang, Yue Zhao, Wei Xie, Martijn Schonewille, Chris I. De Zeeuw et al. · 2024 · Protein & Cell
- Super-resolved 3D-STED microscopy identifies a layer-specific increase in excitatory synapses in the hippocampal CA1 region of Neuroligin-3 KO miceNoriko Koganezawa, Kenji Hanamura, Manuela Schwark, Dilja Krueger‐Burg, Hiroshi Kawabe · 2021 · Biochemical and Biophysical Research Communications
- Revealing synaptic nanostructure distribution through automatic dendritic spine segmentation and single-molecule localization microscopyJiahao Zhang, Rohit M. Vaidya, Rujuta Pendharkar, Hee Jung Chung, Paul R. Selvin · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Differential Development of Dendritic Spines in Striatal Projection Neurons of Direct and Indirect Pathways in the Caudoputamen and Nucleus AccumbensHsiao‐Ying Kuo, Ya-Hui Yang, Shih‐Yun Chen, Tzu-Hsin Kuo, Wan-Ting Lin, FC Liu · 2023 · eNeuro
- Reducing Filamin A Restores Cortical Synaptic Connectivity and Early Social Communication Following Cellular Mosaicism in Autism Spectrum Disorder PathwaysMatthew S. Binder, Iris Escobar, Youfen Xu, Aidan M. Sokolov, Longbo Zhang, Angélique Bordey · 2024 · Journal of Neuroscience
- Characterizing spine issues: If offers novel therapeutics to Angelman syndromeXin Yang · 2020 · Developmental Neurobiology
- Intravital Imaging of Fluorescent Protein Expression in Mice with a Closed-Skull Traumatic Brain Injury and Cranial Window Using a Two-Photon MicroscopeJianjun Zhong, Georgia Gunner, Nils Henninger, Dorothy P. Schafer, Daryl A. Bosco · 2023 · Journal of Visualized Experiments
- Altered projection-specific synaptic remodeling and its modification by oxytocin in an idiopathic autism marmoset modelJun Noguchi, Satoshi Watanabe, Tomofumi Oga, Risa Isoda, Keiko Nakagaki, Kazuhisa Sakai, Kayo Sumida, Kohei Hoshino, Koichi Saito, Izuru Miyawaki et al. · 2024 · Communications Biology
- Transcriptomic Evidence Reveals the Dysfunctional Mechanism of Synaptic Plasticity Control in ASDChao Kong, Zhitong Bing, Lei Yang, Zi‐Gang Huang, Wen-Xu Wang, Celso Grebogi · 2024 · Genes
- Decreased Expression of Synaptophysin 1 (SYP1 Major Synaptic Vesicle Protein p38) and Contactin 6 (CNTN6/NB3) in the Cerebellar Vermis of reln Haplodeficient MiceClaudia Castagna, Adalberto Merighi, Laura Lossi · 2019 · Cellular and Molecular Neurobiology
- Impaired actin dynamics and suppression of Shank2-mediated spine enlargement in cortactin knockout miceShinji Tanaka, Yasutaka Masuda, Akihiro Harada, Shigeo Okabe · 2020 · Microscopy
- Excessive ERK-dependent synaptic clustering drives enhanced motor learning in the MECP2 duplication syndrome mouse model of autismRyan Thomas Ash, Shelly Alexandra Buffington, Jiyoung Park, Mauro Costa‐Mattioli, Huda Yahya Zoghbi, Stelios M. Smirnakis · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
- Induction of LTP mechanisms in dually innervated dendritic spinesJonathan E. Tullis, Karl Ulrich Bayer · 2024 · Scientific Reports
- Elimination of the extra chromosome of Dup15q syndrome iPSCs for cellular and molecular investigationHaruka Munezane, Keiko Imamura, Naoko Fujimoto, Akitsu Hotta, Hiroshi Yukitake, Haruhisa Inoue · 2024 · European Journal of Cell Biology
- RO4938581, a GABAA-α5 negative allosteric modulator rescued behavioral and EEG phenotypes of a mouse model of Dup15q syndromeRyoko Nakagawa, Francesca Nani, Joerg F. Hipp, Michael Honer, Frédéric Knoflach, Rodolfo Gasser, Laurence Ozmen, Kota Tamada, Fatiha Fjeldskaar, Livia Takacs et al. · 2026 · Molecular Psychiatry
- Neonatal social isolation increases the proportion of the immature spines in the layer 2/3 pyramidal neurons of the somatosensory cortexRisa Iguchi, Shinji Tanaka, Shigeo Okabe · 2019 · Neuroscience Research
- In VivoObservation of Structural Changes in Neocortical Catecholaminergic Projections in Response to Drugs of AbuseMai M Morimoto, Shinji Tanaka, Shunsuke Mizutani, Shinji Urata, Kazuto Kobayashi, Shigeo Okabe · 2018 · eNeuro
- Extracellular Matrix Muscle Arm Development Defective Protein Cooperates with the One Immunoglobulin Domain Protein To Suppress Precocious Synaptic RemodelingChunhong Chen, Huiyuan Fu, Ping He, Peng Hui Yang, Haijun Tu · 2021 · ACS Chemical Neuroscience
- Technical Toolbox for Decoding Synaptic ComplexityLaxmi Kumar Parajuli · 2018 · Juntendō Igaku/Juntendo igaku
- miR-199a functions downstream of MeCP2 in neurons of MECP2 duplication syndrome modelsYuichi Akaba, Satoru Takahashi, Shota Adachi, Masatoshi Nishimura, Keiichiro Suzuki, Hideyuki Nakashima, Kinichi Nakashima, Ryutaro Kira, Pin Fee Chong, Yasunari Sakai et al. · 2025 · iScience
- Integrative Approach to Child and Adolescent Mental HealthSeung-Pil Jung · 2017 · InTech eBooks
- Comparative Perspectives on the Function of Oxytocin in Fish and MammalsSaori Yokoi, Larry J. Young, Hideaki Takeuchi · 2022 · Springer eBooks
- Development and Application of Technology for Neural Circuit Visualization - Secondary PublicationShigeo Okabe · 2024 · JMA Journal
- Training Schedule Affects Operant Responding Independent of Motivation in the Neuroligin‐3 R451C Mouse Model of AutismRiki Dingwall, Carlos May, Jackson A. McDonald, Thomas Hill, Robyn M. Brown, Andrew John Lawrence, Anthony John Hannan, Emma L. Burrows · 2025 · Genes Brain & Behavior
- Imaging Synapse Formation and Remodeling In Vitro and In VivoShigeo Okabe · 2019 · Springer eBooks
- Dendritic spine abnormalities in a mouse model of Fragile X syndromeAdam Aharon · 2015 · eScholarship (California Digital Library)
- In Vivo Visualization of Single Axons and Synaptic Remodeling in Normal and Pathological ConditionsFederico W. Grillo, Alison Jane Canty, Peter S. Bloomfield, Vincenzo De Paola · 2016 · Elsevier eBooks
- Molecular Assembly of Excitatory SynapsesHirohide Iwasaki, Shinji Tanaka, Shigeo Okabe · 2016 · Springer eBooks
- C2-P-05In vivo two-photon imaging of synapse dynamics in mouse models of autismShinji Tanaka, Masaaki Isshiki, Toshihiko Kuriu, Katsuhiko Tabuchi, Toru Takumi, Shigeo Okabe · 2015 · Microscopy
- Visualizing inhibitory and excitatory synapse dynamics In vivoKalen Berry · 2018 · DSpace@MIT (Massachusetts Institute of Technology)
- “Memory” in the Mammalian BrainJaichandar Subramanian · 2016 · Annals of SBV
- The impact of the interaction between Neuroligin3 and CYFIP1 on phenotypes associated with Autism Spectrum DisordersMonika Śledziowska · 2020 · ORCA Online Research @Cardiff (Cardiff University)
- Analysis of cortical network dynamics in the behavioral state of a mouse model of autismNobuhiro Nakai, Toru Takumi · 2023 · Folia Pharmacologica Japonica
- Neurobiological Foundations of Psychiatry: OverviewTadafumi Kato · 2023 · Springer eBooks
- Neurobiological Foundations of Psychiatry: OverviewTadafumi Kato · 2024 · Springer eBooks
- Impaired metabotropic glutamate type 5 receptor signaling in the dorsal striatum of the R451C-neuroligin 3 mouse model of Autism Spectrum DisorderMaria Meringolo, Martina Montanari, Simona D’Antoni, Giuseppina Martella, Ilham El Atiallah, Giulia Ponterio, Annalisa Tassone, Ingrid Reverte, Daniele Caprioli, Georgios Strimpakos et al. · 2024 · Research Square
- Impaired metabotropic glutamate type 5 receptor signaling in the dorsal striatum of the R451C-neuroligin 3 mouse model of Autism Spectrum DisorderMaria Meringolo, Martina Montanari, Simona D’Antoni, Giuseppina Martella, Ilham El Atiallah, Giulia Ponterio, Annalisa Tassone, Ingrid Reverte, Daniele Caprioli, Georgios Strimpakos et al. · 2025 · Research Square
- Spine nanostructure profiling of cultured neurons from mouse models reveals a schizophrenia-linked role for Ecrg4Yutaro Kashiwagi, Qingrui Liu, Yasuhiro Go, Ryo� Saito, Atsu Aiba, Takanobu Nakazawa, Shigeo Okabe · 2026 · eLife
- Spine nanostructure profiling of cultured neurons from mouse models reveals a schizophrenia-linked role for Ecrg4Yutaro Kashiwagi, Qingrui Liu, Yasuhiro Go, Ryo Saito, Atsu Aiba, Takanobu Nakazawa, Shigeo Okabe · 2025 · eLife
- Decoding Spine Nanostructure in Mental Disorders Reveals a Schizophrenia-Linked Role for Ecrg4Yutaro Kashiwagi, Qingrui Liu, Yasuhiro Go, Ryo Saito, Atsu Aiba, Takanobu Nakazawa, Shigeo Okabe · 2025 · eLife
- Shank3B deficiency disrupts GABAergic synaptic transmission in pyramidal neurons of the medial prefrontal cortex region in autism spectrum disorderHang Yin, Ke Sun, Chenyang Wang, Songqiao Fan, Jiaqi Wang, Shitai He, Hui meng Lei, Shuo Pang, Jie Chen, G G Zhang · 2026 · Molecular Brain
- Behavioral and synaptic consequences following removal of the Il1rapl1 gene in mice, a model of intellectual disabilityXander Houbaert · 2014 · theses.fr (ABES)
- Etude du développement cortical à travers la caractérisation d'un modèle murin d'autisme et l'inférence des interactions cellulaires par séquençage en cellules uniquesRémi Mathieu · 2022 · theses.fr (ABES)
- Alteration and targeting of microglia in congenital cytomegalovirus infection of the brainCarla Crespo-Quiles · 2022
- The role of transcription factor Neurod2 in cortex development and its implications in neurodevelopmental disordersKaren Runge · 2022 · theses.fr (ABES)
- Gut microbiota-derived 5-HTP penetrates the host blood–brain barrier and ameliorates autism symptomsBei Li, Qianqian Yang, Min Li, Junqing He, Zhiqi Zhang, Xuchun Wan, Zihao Mo, Ruizhen Li, Shihan Li, Weirong Xu et al. · 2026 · Acta Pharmaceutica Sinica B
- Decoding spine nanostructure in cultured neurons derived from mouse models of mental disorder reveals a schizophrenia-linked role for Ecrg4Yutaro Kashiwagi, Qingrui Liu, Yasuhiro Go, Ryo Saito, Atsu Aiba, Takanobu Nakazawa, Shigeo Okabe · 2026 · eLife
- Decoding spine nanostructure in cultured neurons derived from mouse models of neuropsychiatric disorder reveals a schizophrenia-linked role for Ecrg4Yutaro Kashiwagi, Qingrui Liu, Yasuhiro Go, Ryo Saito, Atsu Aiba, Takanobu Nakazawa, Shigeo Okabe · 2026 · eLife