Transcriptome analysis reveals dysregulation of innate immune response genes and neuronal activity-dependent genes in autism

Gupta, Simone, Ellis, Shannon E., Ashar, Foram N., Moes, Anna, Bader, Joel S., Zhan, Jianan, West, Andrew B., Arking, Dan E.·2014·Nature Communications

DOI 10.1038/ncomms6748

Cited by (531)

Items 301–400 of 531

Dysregulation of Alternative Poly-adenylation as a Potential Player in Autism Spectrum Disorder
Krzysztof J. Szkop, Peter I. C. Cooke, Joanne A. Humphries, Viktoria Kalna, David S. Moss, Eugene F. Schuster, Irene Nobeli · 2017 · Frontiers in Molecular Neuroscience
The Role of Connexins in Gastrointestinal Diseases
Jeremy F. Wong, Jasmine Chopra, Lorraine Lok-Wing Chiang, Tong Liu, Jeffery Ho, William Ka Kei Wu, Gary Tse, Sunny Hei Wong · 2019 · Journal of Molecular Biology
Translatome analysis of tuberous sclerosis complex 1 patient-derived neural progenitor cells reveals rapamycin-dependent and independent alterations
Inci Sevval Aksoylu, Pauline Martin, Francis Robert, Krzysztof J. Szkop, Nicholas E. Redmond, Srirupa Bhattacharyya, Jennifer P Wang, Shan Chen, Roberta L. Beauchamp, Irene Nobeli et al. · 2023 · Molecular Autism
Microglia signaling in health and disease – Implications in sex-specific brain development and plasticity
Subrata Pramanik, Harini Devi M., Saswata Chakrabarty, Berkay Paylar, Ajay Pradhan, Manisha Thaker, Shamini Ayyadhury, Arulmani Manavalan, Per‐Erik Olsson, Gopal Pramanik et al. · 2024 · Neuroscience & Biobehavioral Reviews
Autism genes and the leukocyte transcriptome in autistic toddlers relate to pathogen interactomes, infection and the immune system. A role for excess neurotrophic sAPPα and reduced antimicrobial Aβ
Christopher Carter · 2019 · Neurochemistry International
Agonal Factors Distort Gene-Expression Patterns in Human Postmortem Brains
Rujia Dai, Yu Chen, Rujia Dai, Yi Wei Jiang, Jianghua Tian, Sihan Liu, Meng Michelle Xu, Miao Li, Jiaqi Zhou, Chunyu Liu et al. · 2021 · Frontiers in Neuroscience
Unravelling the Cerebellar Involvement in Autism Spectrum Disorders: Insights into Genetic Mechanisms and Developmental Pathways
Marika Guerra, Vanessa Medici, Gina La Sala, Donatella Farini · 2024 · Cells
Integrative analysis of transcriptome‐wide association study and mRNA expression profiles identifies candidate genes associated with autism spectrum disorders
Huimei Huang, Shiqiang Cheng, Miao Ding, Yan Fei Wen, Mei Ma, Lu Zhang, Ping Li, Bolun Cheng, Xiao Liang, Li Liu et al. · 2018 · Autism Research
Solving for X: Evidence for sex‐specific autism biomarkers across multiple transcriptomic studies
Lee, Samuel C., Quinn, Thomas P., Lai, Jerry, Kong, Sek Won, Hertz‐Picciotto, Irva, Glatt, Stephen J., Crowley, Tamsyn M., Venkatesh, Svetha, Nguyen, Thin · 2019 · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
Anatomy and Cell Biology of Autism Spectrum Disorder: Lessons from Human Genetics
Kristel T. E. Kleijer, Guillaume Huguet, Julie Tastet, Thomas Bourgeron, J. Peter H. Burbach · 2017 · Advances in anatomy, embryology and cell biology
Cross-tissue integration of genetic and epigenetic data offers insight into autism spectrum disorder
2016
Unsupervised data-driven stratification of mentalizing heterogeneity in autism
Michael Vincent Lombardo, Meng‐Chuan Lai, Bonnie Auyeung et al. · 2015 · bioRxiv (Cold Spring Harbor Laboratory)
Endocannabinoid System Unlocks the Puzzle of Autism Treatment via Microglia
Tangfeng Su, Yu Yan, Qiang Li, Jiacai Ye, Lei Pei · 2021 · Frontiers in Psychiatry
In vivo translocator protein in females with autism spectrum disorder: a pilot study
Chieh-En Jane Tseng, Camila Canales, Rachel E.G. Marcus, Anjali J. Parmar, Baileigh G. Hightower, Jennifer E. Mullett, Meena M. Makary, Alison U. Tassone, Hannah K. Saro, Paige Connors Hickey et al. · 2024 · Neuropsychopharmacology
The role of maternal immune activation in immunological and neurological pathogenesis of autism
Keqin Liu, Yi Huang, Yufei Zhu, Yan Zhao, Xiangyin Kong · 2022 · Journal of Neurorestoratology
Early Chronic Memantine Treatment-Induced Transcriptomic Changes in Wild-Type and Shank2-Mutant Mice
Ye-Eun Yoo, Seungjoon Lee, Woohyun Kim, Hyosang Kim, Changuk Chung, Seungmin Ha, Jinsu Park, Yeonseung Chung, Hyojin Kang, Eunjoon Kim · 2021 · Frontiers in Molecular Neuroscience
Cord blood DNA methylome in newborns later diagnosed with autism spectrum disorder reflects early dysregulation of neurodevelopmental and X-linked genes
Charles E. Mordaunt, Julia M. Jianu, Benjamin I. Laufer, Yihui Zhu, Keith W. Dunaway, Kelly M. Bakulski, Jason I. Feinberg, Heather E. Volk, Kristen Lyall, Lisa Croen et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
Alterations of Purinergic Receptors Levels and Their Involvement in the Glial Cell Morphology in a Pre-Clinical Model of Autism Spectrum Disorders
Lidia Babiec, Anna Wilkaniec, Marta Matuszewska, Ewelina Pałasz, Magdalena Cieślik, Agata Adamczyk · 2023 · Brain Sciences
The Changes of Amygdala Transcriptome in Autism Rat Model After Arginine Vasopressin Treatment
Bo Zhou, Xiaoli Zheng, Yunhua Chen, Xuehui Yan, Jinggang Peng, Yibu Liu, Yi Zhang, Lei Tang, Min Wen · 2022 · Frontiers in Neuroscience
Maternal HIV Infection and Antiretroviral Therapy in Pregnancy: Implications for Vertical Transmission, Fetal Safety, and Long-Term Infant Outcomes
Tudor Fleșeriu, Lorena Elena Meliţ, Cristina Oana Mărginean, Adrian Vlad Pop, Anca-Meda Văsieșiu · 2025 · Pathogens
Innate Immune Dysfunction and Neuroinflammation in Autism Spectrum Disorder (ASD)
H. K. Hughes, Rachel J Moreno, Paul Ashwood · 2024 · FOCUS The Journal of Lifelong Learning in Psychiatry
Intermittent Fasting Improves Social Interaction and Decreases Inflammatory Markers in Cortex and Hippocampus
Martín García‐Juárez, Adamary García-Rodríguez, Gabriela Cruz-Carrillo, Orlando E. Flores-Maldonado, Miguel A. Becerril-García, Lourdes Garza‐Ocañas, Iván Torre-Villalvazo, Alberto Camacho‐Morales · 2024 · Molecular Neurobiology
Single-cell genomics and regulatory networks for 388 human brains
Prashant S. Emani, Jason J. Liu, Declan Clarke et al. · 2024 · bioRxiv
Alternative splicing and gene co-expression network-based analysis of dizygotic twins with autism-spectrum disorder and their parents
Kaan Okay, Pelin Ünal Varış, Süha Miral, Burcu Ekinci, Tutku Yaraş, Gökhan Karakülah, Yavuz Oktay · 2021 · Genomics
Current status of biological treatment options in Autism Spectrum Disorder
Valsamma Eapen, Laura E. Nicholls, Vanessa Spagnol, Nisha Elizabeth Mathew · 2017 · Asian Journal of Psychiatry
Methylmercury chloride exposure exacerbates existing neurobehavioral and immune dysfunctions in the BTBR T+ Itpr3tf/J mouse model of autism
Haneen A. Al‐Mazroua, Ahmed Nadeem, Mushtaq Ahmad Ansari, Sabry Mohamed Attia, Thamer H. Albekairi, Saleh A. Bakheet, Abdulelah F. Alobaidi, Khaled A. Alhosaini, Saleh Abdullah Alqarni, Khalid E. Ibrahim et al. · 2022 · Immunology Letters
Putative contributions of the sex chromosome proteins SOX3 and SRY to neurodevelopmental disorders
Tahira, Ana Carolina, Barbosa, André Rocha, Feltrin, Arthur Sant'Anna, Gastaldi, Vinicius Daguano, de Toledo, Victor Hugo Calegari, de Carvalho Pereira, José Geraldo, Lisboa, Bianca Cristina Garcia, de Souza Reis, Viviane Neri, dos Santos, Ana Cecília Feio, Maschietto, Mariana et al. · 2019 · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
Developmental convergence and divergence in human stem cell models of autism spectrum disorder
Aaron Gordon, Se‐Jin Yoon, Lucy K. Bicks, Jacqueline M. Martín, Greta Pintacuda, Stephanie Arteaga, Brie Wamsley, Qiuyu Guo, Lubayna S. Elahi, Ricardo E. Dolmetsch et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
Molecular cascades and cell-type specific signatures in ASD revealed by single cell genomics
B. Wamsley, L. Bicks, Yu-Yan Cheng et al. · 2023 · bioRxiv
IUPHAR review: Targeted therapies of signaling pathways based on the gut microbiome in autism spectrum disorders: Mechanistic and therapeutic applications
Abdullah Al Mamun, Peiwu Geng, Shuanghu Wang, Chuxiao Shao, Jian Xiao · 2024 · Pharmacological Research
High-Risk, High-Reward Genetics in ASD
Christina A. Castellani, Dan E. Arking · 2020 · Neuron
Autism genetics perturb prenatal neurodevelopment through a hierarchy of broadly-expressed and brain-specific genes
Vahid Gazestani, Austin W.T. Chiang, Eric Courchesne, Nathan E. Lewis · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
Mast Cells in Autism Spectrum Disorder—The Enigma to Be Solved?
Eleonora Kovacheva, Maria Gevezova, Michael H. J. Maes, Victoria Stepan Sarafian · 2024 · International Journal of Molecular Sciences
The use of CranioSacral therapy for Autism Spectrum Disorders: Benefits from the viewpoints of parents, clients, and therapists
Susan Vaughan Kratz, Jane Kerr, Lorraine Porter · 2016 · Journal of Bodywork and Movement Therapies
Sex-biased single-cell genetic landscape in mice with autism spectrum disorder
Qian Zhang, Yongjie Wang, Jie Tao, Ruixue Xia, Yijie Zhang, Zhirui Liu, Jiwei Cheng · 2023 · Journal of genetics and genomics/Journal of Genetics and Genomics
Cadmium Exposure Is Associated with Behavioral Deficits and Neuroimmune Dysfunction in BTBR T+ Itpr3tf/J Mice
Mohammed Mufadhe Alanazi, Mushtaq Ahmad Ansari, Ahmed Nadeem, Sabry Mohamed Attia, Saleh A. Bakheet, Haneen A. Al‐Mazroua, Abdullah A. Aldossari, Mohammed M. Almutairi, Thamer H. Albekairi, Marwa H. Hussein et al. · 2023 · International Journal of Molecular Sciences
Loss of Katnal2 leads to ependymal ciliary hyperfunction and autism-related phenotypes in mice
Ryeonghwa Kang, Kyungdeok Kim, Yewon Jung, Sang‐Han Choi, Chanhee Lee, Geun Ho Im, Miram Shin, Kwangmin Ryu, Subin Choi, Esther Yang et al. · 2024 · PLoS Biology
Brain region and gene dosage-differential transcriptomic changes in Shank2-mutant mice
Ye-Eun Yoo, Taesun Yoo, Hyojin Kang, Eunjoon Kim · 2022 · Frontiers in Molecular Neuroscience
Transcriptomic analysis in the striatum reveals the involvement of Nurr1 in the social behavior of prenatally valproic acid-exposed male mice
Hyun-Ju Kim, Ran‐Sook Woo, Eun-Jeong Yang, Han-Byeol Kim, Eun hwa Jo, Sangjoon Lee, Hye-Sun Kim, Seonghan Kim, Hye-Sun Kim · 2022 · Translational Psychiatry
Candidate biomarkers from the integration of methylation and gene expression in discordant autistic sibling pairs
Samuel Perini, Michele Filosi, The Italian Autism Network, Giovanni Allibrio, Ilaria Basadonne, Arianna Benvenuto, Serafino Buono, Carmela Bravaccio, Carlo Casonato, Elisa Ceppi et al. · 2023 · Translational Psychiatry
Loss of neurodevelopmental-associated miR-592 impairs neurogenesis and causes social interaction deficits
Yu Fu, Yang Zhou, Yuanlin Zhang, Bo Zhao, Xing-liao Zhang, Wanting Zhang, Yijun Lu, Aiping Lu, Jun Zhang, Jing Zhang · 2022 · Cell Death and Disease
Sexual dimorphism of complement-dependent microglial synaptic pruning and other immune pathways in the developing brain
Daria Prilutsky, Alvin T. Kho, Ariel Feiglin, Timothy Hammond, Beth Stevens, Isaac S. Kohane · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
Antihuman Endogenous Retrovirus Immune Response and Adaptive Dysfunction in Autism
Alessandra Carta, Maria Antonietta Manca, Chiara Scoppola, Elena Rita Simula, Marta Noli, Stefano Ruberto, Marta Conti, Ignazio Roberto Zarbo, Roberto Antonucci, Leonardo Antonio Sechi et al. · 2022 · Biomedicines
Cell Type-Specific Gene Network-Based Analysis Depicts the Heterogeneity of Autism Spectrum Disorder
Jinting Guan, Yiping Lin, Guoli Ji · 2020 · Frontiers in Cellular Neuroscience
Phenotypic Subtyping and Re-analyses of Existing Transcriptomic Data from Autistic Probands in Simplex Families Reveal Differentially Expressed and ASD Trait-Associated Genes
Valerie Wailin Hu, Chongfeng Bi · 2020 · Frontiers in Neurology
The Exposure to Lead (Pb) Exacerbates Immunological Abnormalities in BTBR T+ Itpr3tf/J Mice through the Regulation of Signaling Pathways Relevant to T Cells
Mohammed A. Assiri, Thamer H. Albekairi, Mushtaq Ahmad Ansari, Ahmed Nadeem, Sabry Mohamed Attia, Saleh A. Bakheet, Mudassar Shahid, Abdullah A. Aldossari, Mohammed M. Almutairi, Taghreed N. Almanaa et al. · 2023 · International Journal of Molecular Sciences
Hierarchical cortical transcriptome disorganization in autism
Lombardo, Michael V., Courchesne, Eric, Lewis, Nathan E., Pramparo, Tiziano · 2016
Covariate-dependent negative binomial factor analysis of RNA sequencing data
Siamak Zamani Dadaneh, Mingyuan Zhou, Xiaoning Qian · 2018 · Bioinformatics
Regional skull translocator protein elevation in autistic adults detected by PET-MRI
Chieh-En Jane Tseng, Elisa Guma, Christopher J. McDougle, Jacob M. Hooker, Nicole R. Zürcher · 2025 · Brain Behavior and Immunity
Gene Dosage- and Age-Dependent Differential Transcriptomic Changes in the Prefrontal Cortex of Shank2-Mutant Mice
Seungjoon Lee, Hyojin Kang, Hwajin Jung, Eunjoon Kim, Eunee Lee · 2021 · Frontiers in Molecular Neuroscience
Genomics, transcriptomics, proteomics and big data analysis in the discovery of new diagnostic markers and targets for therapy development
Dong Ik Park · 2020 · Progress in molecular biology and translational science
New Horizons for Molecular Genetics Diagnostic and Research in Autism Spectrum Disorder
Nader Izz Eddin Al-Dewik, Mohammed Alsharshani · 2020 · Advances in neurobiology
Inhibition of TRPV4 rescues circuit and social deficits unmasked by acute inflammatory response in a Shank3 mouse model of Autism
Stamatina Tzanoulinou, Stefano Musardo, Alessandro Contestabile · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
Sex-Differential Gene Expression in Developing Human Cortex and Its Intersection With Autism Risk Pathways
Lee T. Kissel, Sirisha Pochareddy, Joon‐Yong An, Nenad Šestan, Stephan Sanders, Xuran Wang, Donna M. Werling · 2024 · Biological Psychiatry Global Open Science
Integrative genomics identifies a convergent molecular subtype that links epigenomic with transcriptomic differences in autism
Gokul Ramaswami, Hyejung Won, Michael J. Gandal · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
Vitamin D and Atopy
Theoharis Constantin Theoharides · 2017 · Clinical Therapeutics
Integrated analysis of miRNA and mRNA expression profiles in the brains of BTBR mice
Min Wang, Jing He, Yun Zhou, Na Lv, Min Zhao, Hongen Wei, Rongshan Li · 2020 · International Journal of Developmental Neuroscience
Systems biology in the central nervous system: A brief perspective on essential recent advancements
Joseph D. Dougherty, Chengran Yang, Allison M. Lake · 2017 · Current Opinion in Systems Biology
Neuron-specific transcriptomic signatures indicate neuroinflammation and altered neuronal activity in ASD temporal cortex
Pan Zhang, Alicja Omanska, Bradley P. Ander · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
Prolonged STAT1 signaling in neurons causes hyperactive behavior
Danielle N. Clark, Shelby V. Brown, Li Xu, Rae‐Ling Lee, Joey V. Ragusa, Zhenghao Xu, Joshua D. Milner, Anthony J. Filiano · 2024 · Brain Behavior and Immunity
Autism spectrum disorder (ASD)-a case-control study to investigate the prenatal, perinatal and neonatal factors in Indian Population
Balachandar Vellingiri, G. Bharathi, Kaavya Jayaramayya, Anila Venugopal, Mahalaxmi Iyer, Arul Narayanasamy, Avanthika Bharathi, Abilash Valsala Gopalakrishnan, Nachimuthu Senthil Kumar, Mohana Devi Subramaniam · 2021 · Brain Disorders
Genetic variants drive altered epigenetic regulation of endotoxin response in BTBR macrophages
Annie Vogel Ciernia, Verena M. Link, Milo Careaga, Janine M. LaSalle, Paul Ashwood · 2020 · Brain Behavior and Immunity
Modeling Inflammation on Neurodevelopmental Disorders Using Pluripotent Stem Cells
Beatriz Freitas, Patrícia Cristina Baleeiro Beltrão-Braga, Maria Carolina Marchetto · 2020 · Advances in neurobiology
Extracerebral Dysfunction in Animal Models of Autism Spectrum Disorder
Elisa L. Hill‐Yardin, Sonja J. McKeown, Gaia Novarino, Andreas Martin Grabrucker · 2017 · Advances in anatomy, embryology and cell biology
Pharmaceuticals and Stem Cells in Autism Spectrum Disorders: Wishful Thinking?
Senthilkumar Sivanesan, Aaron Tan, Rebecca Jeyaraj, Jie Min Lam, Monica Gole, Antonio Y. Hardan, Keyoumars Ashkan, Jayakumar Rajadas · 2016 · World Neurosurgery
Untangling the most probable role for vitamin D 3 in autism
Dianne Eyvonn Godar, Stephen J. Merrill · 2017 · Dermato-Endocrinology
The epigenetic regulation of synaptic genes contributes to the etiology of autism
Annamária Srančíková, Zuzana Bačová, Ján Bakoš · 2021 · Reviews in the Neurosciences
Spatio-Temporal Roles of ASD-Associated Variants in Human Brain Development
Yu‐Jin Kim, Joon‐Yong An · 2020 · Genes
CHAS, a deconvolution tool, infers cell type-specific signatures in bulk brain histone acetylation studies of neurological and psychiatric disorders
Kitty B. Murphy, Yuqian Ye, Maria Tsalenchuk, Alexi Nott, Sarah J. Marzi · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
Large 22q13.3 deletions perturb peripheral transcriptomic and metabolomic profiles in Phelan-McDermid syndrome
Michael S. Breen, Xuanjia Fan, Tess Levy, Rebecca M. Pollak, Brett L. Collins, Aya Osman, Anna S. Tocheva, Mustafa Şahin, Elizabeth Berry‐Kravis, Latha Valluripalli Soorya et al. · 2022 · Human Genetics and Genomics Advances
Integrated analysis of genetic, behavioral, and biochemical data implicates neural stem cell-induced changes in immunity, neurotransmission and mitochondrial function in Dementia with Lewy Body mice
Anita Lakatos, Natalie R.S. Goldberg, Mathew M. Blurton-Jones · 2017 · Acta Neuropathologica Communications
Microglia in autism spectrum disorder: heterogeneity, immunometabolism, and synapse-related pathways
Aojie Lian, Mei He, Hong Zhang, Yingmei Yang · 2026 · Frontiers in Immunology
Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap
2016
Transcriptional network analysis on brains reveals a potential regulatory role of PPP1R3F in autism spectrum disorders
Abolfazl Doostparast Torshizi, Jubao Duan, Kai Wang · 2018 · BMC Research Notes
Assessing transcriptomic heterogeneity of single-cell RNASeq data by bulk-level gene expression data
Khong-Loon Tiong, Dmytro A. Luzhbin, Chen‐Hsiang Yeang · 2024 · BMC Bioinformatics
Epigenomic convergence of genetic and immune risk factors in neurodevelopmental disorder cortex
Vogel Ciernia A., Laufer B.I., Dunaway K.W., Hwang H., Mordaunt C.E., Rochelle L. Coulson, Yasui D.H., Janine M. LaSalle · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
Deregulated mRNA and microRNA Expression Patterns in the Prefrontal Cortex of the BTBR Mouse Model of Autism
Catherine Mooney, Andrea Parlante, Giulia Canarutto, Andrea Grigoli, María Luisa Scattoni, Laura Ricceri, Eva Maria Jimenez-Mateos, Amaya Sanz‐Rodriguez, Elena Clementi, Silvano Piazza et al. · 2025 · Molecular Neurobiology
Autism Spectrum Disorder in Preterm Children
Brian Thomas Kalish, Asimenia Angelidou, Jane E. Stewart · 2017 · NeoReviews
Transcriptional regulation of disease-relevant microglial activation programs
Amanda McQuade, Reet Mishra, Venus Hagan, Weiwei Liang, Peter J. Colias, Vincent Cele Castillo, Bianca Gonzalez, Justin P. Lubin, Verena Claudia Haage, Victoria S. Marshe et al. · 2026 · Neuron
Exploring the Potential Role of ADAM 17 and ADAM 22 in the Etiology of Autism Spectrum Disorders
Sarah H. Al-Mazidi, A. el-Ansary, Amani Abualnaja, Abdullah F Alzarroug, Turki Alharbi, Laila Al-Ayadhi · 2023 · Brain Science
A meta-analysis of two high-risk prospective cohort studies reveals autism-specific transcriptional changes to chromatin, autoimmune, and environmental response genes in umbilical cord blood
Charles E. Mordaunt, Bo Young Park, Kelly M. Bakulski, Jason I. Feinberg, Lisa Croen, Christine Ladd‐Acosta, Craig J. Newschaffer, Heather E. Volk, Sally J. Ozonoff, Irva Hertz‐Picciotto et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
Reply to Lombardo, 2020: An additional route of investigation: what are the mechanisms controlling ribosomal protein genes dysregulation in autistic neuronal cells?
Karina Griesi‐Oliveira, Maria Rita Passos‐Bueno · 2020 · Molecular Psychiatry
ASDmiR: A Stepwise Method to Uncover miRNA Regulation Related to Autism Spectrum Disorder
Chenchen Xiong, Shaoping Sun, Weili Jiang, Lei Ma, Junpeng Zhang · 2020 · Frontiers in Genetics
Global changes in patterning, splicing and primate specific lncRNAs in autism brain
Neelroop Parikshak, Vivek Swarup, T. Grant Belgard, Michael J. Gandal, Manuel Irimia, Virpi Leppä, Jennifer K. Lowe, Robert Johnson, Benjamin J. Blencowe, Steve Horvath et al. · 2016 · bioRxiv (Cold Spring Harbor Laboratory)
Genome-wide DNA methylation patterns in Autism Spectrum Disorder and mitochondrial function
Sofia Stathopoulos, Renaud Gaujoux, Colleen O’Ryan · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
Cadmium exposure exacerbates immunological abnormalities in a BTBR T+ Itpr3tf/J autistic mouse model by upregulating inflammatory mediators in CD45R-expressing cells
Thamer H. Albekairi, Mohammed Mufadhe Alanazi, Mushtaq Ahmad Ansari, Ahmed Nadeem, Sabry Mohamed Attia, Saleh A. Bakheet, Haneen A. Al‐Mazroua, Abdullah A. Aldossari, Taghreed N. Almanaa, Mohammad Y. Alwetaid et al. · 2023 · Journal of Neuroimmunology
Evolutionary and biomedical implications of sex differences in the primate brain transcriptome
Alex R. DeCasien, Kenneth L. Chiou, Camille Testard et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
Transcriptomic Analysis Reveals Abnormal Expression of Prion Disease Gene Pathway in Brains from Patients with Autism Spectrum Disorders
Salvo Danilo Lombardo, Giuseppe Battaglia, Maria Cristina Petralia, Katia Mangano, Maria Sofia Basile, Valeria Bruno, Paolo Fagone, Rita Bella, Ferdinando Nicoletti, Eugenio Cavalli · 2020 · Brain Sciences
Genetic heterogeneity in autism: from single gene to a pathway perspective
Joon‐Yong An, Charles Claudianos · 2016 · bioRxiv (Cold Spring Harbor Laboratory)
Weighted Gene Co-Expression Network Analysis Reveals Dysregulation of Mitochondrial Oxidative Phosphorylation in Eating Disorders
Liulin Yang, Yun Li, Turki Turki, Huizi Tan, Zhi Wei, Xiao Chang · 2018 · Genes
X Chromosome Inactivation Timing is Not eXACT: Implications for Autism Spectrum Disorders
Janine M. LaSalle · 2022 · Frontiers in Genetics
CHD8 adulthood microglial knockdown in C57BL6 mice induces behavioral, morphological, and transcriptional changes in a sex-dependent manner
Orly Weissberg, Ram Harari, Chizim Dogun, Dmitriy Getselter, Evan Elliott · 2025 · Translational Psychiatry
Comprehensive investigation of temporal and autism-associated cell type composition-dependent and independent gene expression changes in human brains
Qianhui Yu, Zhisong He · 2016 · bioRxiv (Cold Spring Harbor Laboratory)
Microglia from offspring of dams with allergic asthma exhibit epigenomic alterations in genes dysregulated in autism
Annie Vogel Ciernia, Milo Careaga, Janine M. LaSalle · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
The mast cells - Cytokines axis in Autism Spectrum Disorder
Eleonora Kovacheva, Maria Gevezova, Michael H. J. Maes, Victoria S Sarafian · 2024 · Neuropharmacology
Post-transcriptionally impaired de novo mutations contribute to the genetic etiology of four neuropsychiatric disorders
Fengbiao Mao, Lu Wang, Xiaolu Zhao, Zhongshan Li, Luoyuan Xiao, Rajesh C. Rao, Jinchen Li, Huajing Teng, Xin He, Zhong Sheng Sun · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
Microglia as critical mediators linking perinatal immune stress to mental health trajectories
Ravikiran M. Raju, Caroline J. W. Smith · 2025 · Neuropsychopharmacology
Profiling of activated monocyte populations in autism and associations with increased severity and comorbid behaviors
Elizabeth Breece, Rachel J Moreno, Yasmin W. Azzam, Sally J. Rogers, Paul Ashwood · 2024 · Brain Behavior and Immunity
Single-nucleus gene and gene set expression-based similarity network fusion identifies autism molecular subtypes
Junjie Zhang, Guoli Ji, Xilin Gao, Jinting Guan · 2023 · BMC Bioinformatics
Transcriptome Analysis of Cortical Tissue Reveals Shared Sets of Down-Regulated Genes in Autism and Schizophrenia
Shannon Ellis, Rebecca Panitch, Andrew B. West · 2015 · bioRxiv (Cold Spring Harbor Laboratory)