Regulation of nucleotide metabolism by mutant p53 contributes to its gain-of-function activities
Kollareddy, Madhusudhan, Dimitrova, Elizabeth, Vallabhaneni, Krishna C., Chan, Adriano, Le, Thuc, Chauhan, Krishna M., Carrero, Zunamys I., Ramakrishnan, Gopalakrishnan +8 more·2015·Nature Communications
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- A prognostic 15-gene model based on differentially expressed genes among metabolic subtypes in diffuse large B-cell lymphomaJun Hou, Peng Guo, Yujiao Lu, Xiaokang Jin, Ke Liang, Na Zhao, Shunxu Xue, Chengmin Zhou, Bing Wang, Zhu Xin et al. · 2023 · Pathology & Oncology Research
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- ENY2 transcription and export complex 2 subunit deficiency induces nucleolar stress to inhibit tumor progression through NPM1/MDM2/p53-dependent and -independent responsesShiqi Zuo, He S, Zhiqin Zhu, Yanjie Hou, Ziqing Wu, Yao Tang, Yujiao Zou · 2026 · Cellular Oncology
- Dynamic control of nucleotide metabolism in physiology and diseaseDohun Kim, Gerta Hoxhaj · 2026 · Nature Cell Biology
- Development of Novel Therapeutic Response BiomarkersNils Elander, Karen Aughton, William Greenhalf · 2018 · Springer eBooks
- The tAnGo fell short of inspiring the audienceDimitriοs Mavroudis · 2017 · The Lancet Oncology
- Development of Novel Therapeutic Response BiomarkersNils Elander, Karen Aughton, William Greenhalf · 2017 · Springer eBooks
- Gain-of-function and dominant-negative effects of distinct p53 mutations in lung tumoursFrances K. Turrell · 2018 · Apollo (University of Cambridge)
- Defining Roles of Metabolic Reprogramming in Pancreatic Tumorigenesis and Tumor MaintenanceBarbara Scott Nelson · 2020 · Deep Blue (University of Michigan)
- Mutant p53 Associates with Human Equilibrative Nucleoside 1 Upregulation and Better Response to Adjuvant Gemcitabine in Intrahepatic Cholangiocarcinoma PatientsMarzia Deserti, Valeria Relli, Andrea Palloni, Francesco Vasuri, Deborah Malvi, Alessio Degiovanni, Simone Rimedio, Chiara Delbaldo, Chiara Deiana, Giovanni Brandi et al. · 2025 · International Journal of Molecular Sciences
- TP53-dependent antitumor effects of DHODH Inhibition in nasopharyngeal carcinomaXingchen Dong, Yaoting Zhang, Zhicun Zhang, Ting Liu, Dongsheng Gu · 2025 · Discover Oncology
- Deoxycytidine kinase inhibition: Rewiring tumor nucleotide metabolism for therapeutic gainPeter M. Clark, Curtis B. Thompson, Kenneth A. Schultz · 2026 · Nucleosides Nucleotides & Nucleic Acids
- Apprentissage de réseaux causaux avec variables latentes et applications à des contextes génomiques et cliniquesLouis Verny · 2017
- Network analysis of genomic and clinical dataNadir Sella · 2019
- Revisiting tumor immunogenicity through the lens of mutant p53: Implications for cancer immunotherapySourio Chakraborty, Sumon Mukherjee, Subhajit Ghosh, Udit Basak, Sumoyee Mukherjee, Arghya Adhikary, Gaurisankar Sa, Tanya Das · 2026 · APOPTOSIS
- Ribonucleotide Reductase Inhibition Triggers Ferroptosis in Genetically Defined Subsets of Non–Small Cell Lung CancerUtsav Sen, Dalia S. Natour, Subhamoy Chakraborty, Élisa Gobbini, Chih-wei Fan, Calvin Koelbel, Andrew Elliott, Ari M. Vanderwalde, Hossein Borghaei, Balázs Halmos et al. · 2026 · Cancer Research Communications
- In Cellulo Observation of De Novo -Synthesized Nucleotide by Spectral Tracing of Glutamine-Derived Nitrogen Metabolism (QN-STIM) in Cancer CellsJiro Karlo, Surya Pratap Singh · 2026 · Analytical Chemistry