Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A

Wong, Pui-Mun, Feng, Yan, Wang, Junru, Shi, Rong, Jiang, Xuejun·2015·Nature Communications

Cited by (239)

Items 101–200 of 239

  1. Autophagy in cancer immunotherapy: Perspective on immune evasion and cell death interactions
    Qiang Yu, Jiajun Ding, Shisen Li, Yunlong Li · 2024 · Cancer Letters
  2. Dihydroartemisinin as a Sensitizing Agent in Cancer Therapies
    Qingrong Li, Qiang Ma, Jibing Cheng, Xi Zhou, Wen-Jie Pu, Xiaowu Zhong, Xiaolan Guo · 2021 · OncoTargets and Therapy
  3. Type one protein phosphatase regulates fixed-carbon starvation-induced autophagy in Arabidopsis
    Qiuling Wang, Qianqian Qin, Meifei Su, Na Li, Jing Zhang, Yang Liu, Longfeng Yan, Suiwen Hou · 2022 · The Plant Cell
  4. Multilayered regulation of autophagy by the Atg1 kinase orchestrates spatial and temporal control of autophagosome formation
    Anne Schreiber, Ben C. Collins, Colin T. Davis, Radoslav Ivanov Enchev, Angie Sedra, Rocco D’Antuono, Ruedi H. Aebersold, Matthias Peter · 2021 · Molecular Cell
  5. Activator of G-Protein Signaling 3–Induced Lysosomal Biogenesis Limits Macrophage Intracellular Bacterial Infection
    Ali Vural, Souhaila Al Khodor, Gordon Y. C. Cheung, Chong-Shan Shi, Lalitha Srinivasan, Travis J. McQuiston, Il‐Young Hwang, Anthony J. Yeh, J Blumer, Volker Briken et al. · 2015 · The Journal of Immunology
  6. Macropinocytosis and autophagy crosstalk in nutrient scavenging
    Oliver Florey, Michael Overholtzer · 2018 · Philosophical Transactions of the Royal Society B Biological Sciences
  7. The biological role of metabolic reprogramming in pancreatic cancer
    Tatsunori Suzuki, Motoyuki Otsuka, Takahiro Seimiya, Takuma Iwata, Takahiro Kishikawa, Kazuhiko Koike · 2020 · MedComm
  8. The protein restriction mimetic Resveratrol is an autophagy inducer stronger than amino acid starvation in ovarian cancer cells
    Alessandra Ferraresi, Rossella Titone, Carlo Follo, Andrea Castiglioni, Giovanna Chiorino, Danny N. Dhanasekaran, Ciro Isidoro · 2017 · Molecular Carcinogenesis
  9. Metabolic stress induces a double-positive feedback loop between AMPK and SQSTM1/p62 conferring dual activation of AMPK and NFE2L2/NRF2 to synergize antioxidant defense
    Eun-Ji Choi, Hyun-Taek Oh, Seon-Hyeong Lee, Chen‐Song Zhang, Mengqi Li, Soo‐Youl Kim, Sunghyouk Park, Tong‐Shin Chang, Byung‐Hoon Lee, Sheng‐Cai Lin et al. · 2024 · Autophagy
  10. Conserved signaling pathways genetically associated with longevity across the species
    Abdul Haseeb Khan, Zhiwen Zou, Xiang Dong Yang, Shenghan Chen, Xiao‐Li Tian · 2018 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  11. Preclinical evaluation of a novel triple-acting PIM/PI3K/mTOR inhibitor, IBL-302, in breast cancer
    Sean P. Kennedy, Michael F. O‘Neill, Darren Cunningham, Patrick Glyn Morris, Sinéad Toomey, Carmen Blanco‐Aparicio, Sonia Martı́nez, Joaquı́n Pastor, Alex J. Eustace, Bryan T. Hennessy · 2020 · Oncogene
  12. Lysine crotonylation regulates leucine-deprivation-induced autophagy by a 14-3-3ε-PPM1B axis.
    Z. Zheng, Guokai Yan, Xiuzhi Li, Yu-Ke Fei, Ling-Ling Sun, Hao-Nan Yu, Yao-Rong Niu, Wei-Hua Gao, Qing Zhong, Xiang-Hua Yan · 2022 · Cell Reports
  13. Function and regulation of ULK1: From physiology to pathology
    Ze Rong, Kaifeng Zheng, Jun Chen, Xiaofeng Jin · 2022 · Gene
  14. Association Between Atg5-independent Alternative Autophagy and Neurodegenerative Diseases
    Shinya Honda, Satoko Arakawa, Hirofumi Yamaguchi, Satoru Torii, Hajime Tajima Sakurai, Masatsune Tsujioka, Michiko Murohashi, Shigeomi Shimizu · 2020 · Journal of Molecular Biology
  15. Targeted elimination of senescent Ras-transformed cells by suppression of MEK/ERK pathway
    Elena Y. Kochetkova, Galina I. Blinova, Olga A. Bystrova, Marina G. Martynova, Valery A. Pospelov, Tatiana V. Pospelova · 2017 · Aging
  16. Autophagy Regulation by the Translation Machinery and Its Implications in Cancer
    Pilar Sarah Acevo-Rodríguez, Giovanna Maldonado, Susana Castro‐Obregón, Greco Hernández · 2020 · Frontiers in Oncology
  17. Roles of autophagy and metabolism in pancreatic cancer cell adaptation to environmental challenges.
    Sandrina Maertin, Jason M. Elperin, Ethan Lotshaw, M. Sendler, S. Speakman, Kazuki Takakura, B. Reicher, O. Mareninova, P. Grippo, J. Mayerle et al. · 2017 · American Journal of Physiology - Gastrointestinal and Liver Physiology
  18. Knockdown of periostin attenuates 5/6 nephrectomy‐induced intrarenal renin–angiotensin system activation, fibrosis, and inflammation in rats
    Xiaohui Bian, Yu Bai, Xiaoxiao Su, Guifeng Zhao, Guangping Sun, Detian Li · 2019 · Journal of Cellular Physiology
  19. Circadian Genes as Therapeutic Targets in Pancreatic Cancer
    María García-Costela, Julia Escudero-Feliú, Jose D. Puentes-Pardo, Sara Moreno-SanJuan, Sonia Morales, Sandra Ríos‐Arrabal, Ángel Carazo, Josefa León · 2020 · Frontiers in Endocrinology
  20. PP2A mediates apoptosis or autophagic cell death in multiple myeloma cell lines
    Hang Zhou, Wei Luo, Chao Zeng, Yu Zhang, Liyang Wang, Wenxiu Yao, Chunlai Nie · 2017 · Oncotarget
  21. Ca2+/calmodulin-dependent protein kinase II β decodes ER Ca2+ transients to trigger autophagosome formation
    Qiaoxia Zheng, Huan Zhang, Hongyu Zhao, Yong Chen, Hongzhining Yang, Tingting Li, Qixu Cai, Yingyu Chen, Youjun Wang, Mingjie Zhang et al. · 2024 · Molecular Cell
  22. Dual targeting of androgen receptor and mTORC1 by salinomycin in prostate cancer
    Nooshin Mirkheshti, Sul-Gi Park, Shoulei Jiang, Jodie D. Cropper, Sherry L. Werner, Chung Seog Song, Bandana Chatterjee · 2016 · Oncotarget
  23. PHD2 Targeting Overcomes Breast Cancer Cell Death upon Glucose Starvation in a PP2A/B55α-Mediated Manner
    Giusy Di Conza, Sarah Trusso Cafarello, Xingnan Zheng, Qing Hua Zhang, Massimiliano Mazzone · 2017 · Cell Reports
  24. Histone deacetylase 5 deacetylates the phosphatase PP2A for positively regulating NF-κB signaling
    Chonghui Xu, Jielin Tang, Qi Yang, He Zhao, Yaling Liu, Juan Cao, Yuan Zhou, Xinwen Chen, Jizheng Chen · 2021 · Journal of Biological Chemistry
  25. Rapamycin Enhances Repressed Autophagy and Attenuates Aggressive Progression in a Rat Model of IgA Nephropathy
    Di Liu, Yexin Liu, Guochun Chen, Liyu He, Chengyuan Tang, Chang Wang, Danyi Yang, Huiqiong Li, Zheng Dong, Hong Liu · 2017 · American Journal of Nephrology
  26. [Pemetrexed + Sorafenib] lethality is increased by inhibition of ERBB1/2/3-PI3K-NFκB compensatory survival signaling
    Laurence A. Booth, Jane L. Roberts, Mehrad Tavallai, John Chuckalovcak, Daniel K. Stringer, Antonis E. Koromilas, David L. Boone, William Patrick McGuire, Andrew Stewart Poklepovic, Paul Dent · 2016 · Oncotarget
  27. Autophagic flux inhibition, apoptosis, and mitochondrial dysfunction in bile acids‐induced impairment of human placental trophoblast
    Xi Yang, Yulai Zhou, Huan Li, Fuzhen Song, Juan Li, Yong Jian Zhang, Yi Lin, Huijuan Zhang, Jianxia Fan, Weibin Wu · 2022 · Journal of Cellular Physiology
  28. Defective collagen proteostasis and matrix formation in the pathogenesis of lysosomal storage disorders
    Carmine Settembre, Laura Cinque, Rosa Bartolomeo, Chiara Di Malta, Chiara De Leonibus, Alison R. Forrester · 2018 · Matrix Biology
  29. The Proteasome Inhibitor Bortezomib Affects Chondrosarcoma Cells via the Mitochondria-Caspase Dependent Pathway and Enhances Death Receptor Expression and Autophagy
    Birgit Lohberger, Bibiane Steinecker-Frohnwieser, Nicole Stuendl, Heike Kaltenegger, Andreas Leithner, Beate Rinner · 2016 · PLoS ONE
  30. Epigenetics: An emerging field in the pathogenesis of nonalcoholic fatty liver disease
    Nissar Ul Ashraf, Mohammad Altaf · 2018 · Mutation Research/Reviews in Mutation Research
  31. Ca2+ Signaling and Its Potential Targeting in Pancreatic Ductal Carcinoma
    Louay Bettaieb, Maxime Brulé, Axel Chomy, Mel Diedro, Malory Fruit, Eloise Happernegg, Leila Heni, Anaïs Horochowska, Mahya Housseini, Kekely Klouyovo et al. · 2021 · Cancers
  32. On taking the STING out of immune activation
    Andra Banete, Kyle Seaver, Devyani Bakshi, Katrina Gee, Sameh Basta · 2018 · Journal of Leukocyte Biology
  33. Autophagy supports PDGFRA-dependent brain tumor development by enhancing oncogenic signaling
    Joanne E. Simpson, Morwenna Muir, Martin Lee, Catherine Naughton, Nick Gilbert, Steven M. Pollard, Noor Gammoh · 2023 · Developmental Cell
  34. MAP1B‐LC1 prevents autophagosome formation by linking syntaxin 17 to microtubules
    Kohei Arasaki, Haruki Nagashima, Yuri Kurosawa, Hana Kimura, Naoki Nishida, Naoshi Dohmae, Akitsugu Yamamoto, Shigeru Yanagi, Yuichi Wakana, Hiroki Inoue et al. · 2018 · EMBO Reports
  35. PP2A-B55 Holoenzyme Regulation and Cancer
    Perrine Goguet-Rubio, Priya Amin, Sushil Awal, Suzanne Vigneron, Sophie Charrasse, Francisca Méchali, Jean Claude Labbé, Thierry Lorca, Anna Castro · 2020 · Biomolecules
  36. Epstein-Barr Virus LMP1 Modulates the CD63 Interactome
    Mujeeb R. Cheerathodi, Dingani Nkosi, Allaura S. Cone, Sara B. York, David G. Meckes · 2021 · Viruses
  37. Inducing Temporal and Reversible Autophagy by Nanotopography for Potential Control of Cell Differentiation
    Wen Song, Mengqi Shi, Mingdong Dong, Yumei Zhang · 2016 · ACS Applied Materials & Interfaces
  38. Unc-51-like kinase (ULK) complex-independent autophagy induced by hypoxia
    Yan Feng, Helen H. Kang, Pui‐Mun Wong, Minghui Gao, Ping Wang, Xuejun Jiang · 2018 · Protein & Cell
  39. Mark4 Inhibited the Browning of White Adipose Tissue by Promoting Adipocytes Autophagy in Mice
    Kun Yang, Jiarui Cai, Miao Pan, Qian Sun, Chao Sun · 2020 · International Journal of Molecular Sciences
  40. The emerging roles of ATG1/ATG13 kinase complex in plants
    Qiuling Wang, Suiwen Hou · 2022 · Journal of Plant Physiology
  41. BCL2L1 inhibitor A-1331852 inhibits MCL1 transcription and triggers apoptosis in acute myeloid leukemia cells
    Jing‐Ting Chiou, Yuying Wu, Yuan‐Chin Lee, Long‐Sen Chang · 2023 · Biochemical Pharmacology
  42. Active autophagy in cancer‐associated fibroblasts: Recent advances in understanding the novel mechanism of tumor progression and therapeutic response
    Bikash Chandra Jena, Lipsa Rout, Ankita Dey, Mahitosh Mandal · 2021 · Journal of Cellular Physiology
  43. The “Self-eating” of cancer-associated fibroblast: A potential target for cancer
    Yan Chen, Xiaozhen Zhang, Hanshen Yang, Tingbo Liang, Xueli Bai · 2023 · Biomedicine & Pharmacotherapy
  44. Endoplasmic reticulum stress in the regulation of liver diseases: Involvement of Regulated IRE1α and β‐dependent decay and miRNA
    Harun‐Or Rashid, Hyun‐Kyoung Kim, Raghupatil Junjappa, Hyung‐Ryong Kim, Han–Jung Chae · 2016 · Journal of Gastroenterology and Hepatology
  45. Sodium Tanshinone IIA Sulfonate Ameliorates Oxygen-glucose Deprivation/Reoxygenation-induced Neuronal Injury via Protection of Mitochondria and Promotion of Autophagy
    Zhi Ma, Yue Wu, Juan Xu, Hui Cao, Mingyang Du, Haibo Jiang, Feng Qiu · 2023 · Neurochemical Research
  46. Therapeutic Targeting of Autophagy in Pancreatic Ductal Adenocarcinoma
    Alexander Grenander Raufi, Nicholas R. Liguori, Lindsey Carlsen, Cassandra Parker, Liz J. Hernández Borrero, Shengliang Zhang, Xiaobing Tian, Anna D. Louie, Lanlan Zhou, Attila A. Seyhan et al. · 2021 · Frontiers in Pharmacology
  47. A Deep Insight Into Regulatory T Cell Metabolism in Renal Disease: Facts and Perspectives
    Zhongyu Han, Kuai Ma, Hongxia Tao, Hongli Liu, Jiong Zhang, Xiyalatu Sai, Yunlong Li, Mingxuan Chi, Qing Nian, Linjiang Song et al. · 2022 · Frontiers in Immunology
  48. Advancements in autophagy perturbations in Alzheimer’s disease: Molecular aspects and therapeutics
    Dhapola, Rishika, Kumari, Sneha, Sharma, Prajjwal, Vellingiri, Balachandar, HariKrishnaReddy, Dibbanti · 2025 · Brain Research
  49. mTOR independent alteration in ULK1 Ser758 phosphorylation following chronic LRRK2 kinase inhibition
    Claudia Manzoni, Adamantios Mamais, Sybille Dihanich, Marc P. M. Soutar, Hélène Plun‐Favreau, Rina Bandopadhyay, Rosella Abeti, Paola Giunti, John Hardy, Mark Cookson et al. · 2018 · Bioscience Reports
  50. Regulation PP2Ac methylation ameliorating autophagy dysfunction caused by Mn is associated with mTORC1/ULK1 pathway
    Yilu Xu, Lancheng Wei, Shen Tang, Qianqian Shi, Bin Wu, Xiaobo Yang, Yunfeng Zou, Xinhang Wang, Qingqing Ao, Ling Meng et al. · 2021 · Food and Chemical Toxicology
  51. Autophagy and mitochondrial metabolism: insights into their role and therapeutic potential in chronic myeloid leukaemia
    Pablo Baquero, Amy Dawson, G. Vignir Helgason · 2018 · FEBS Journal
  52. Amino Acids as Regulators of Cell Metabolism
    Semen V. Nesterov, Lev S. Yaguzhinsky, Podoprigora Gi, Yaroslav R. Nartsissov · 2020 · Biochemistry (Moscow)
  53. Sequestration of translation initiation factors in p62 condensates
    Alberto Danieli, Georg Vucak, Manuela Baccarini, Sascha Martens · 2023 · Cell Reports
  54. Amino acids metabolism: a potential target for cancer treatment
    Shiqi Ren, Xinyi Zhou, Zhen Wang, Kefei Yuan · 2025 · Molecular Cancer
  55. The compartmentalised nature of neuronal mitophagy: molecular insights and implications
    Fivos Borbolis, Konstantinos Palikaras · 2022 · Expert Reviews in Molecular Medicine
  56. Co-Targeting the EGFR and PI3K/Akt Pathway to Overcome Therapeutic Resistance in Head and Neck Squamous Cell Carcinoma: What about Autophagy?
    Hannah Zaryouh, Jinthe Van Loenhout, Marc Peeters, Jan Baptist Vermorken, Filip Lardon, An Wouters · 2022 · Cancers
  57. mTOR and SGLT-2 Inhibitors: Their Synergistic Effect on Age-Related Processes
    Dario E. Troise, Silvia Mercuri, Barbara Infante, Vincenzo Losappio, Luciana Antonia Cirolla, Giuseppe Stefano Netti, Elena Ranieri, Giovanni Stallone · 2024 · International Journal of Molecular Sciences
  58. PP2A as the Main Node of Therapeutic Strategies and Resistance Reversal in Triple-Negative Breast Cancer
    Henan Zhao, Duojiao Li, Baojing Zhang, Yan Qi, Yun-Peng Diao, Yuhong Zhen, Xiaohong H. Shu · 2017 · Molecules
  59. Common Traits Spark the Mitophagy/Xenophagy Interplay
    Aarti Singh, Sharon L. Kendall, Michelangelo Campanella · 2018 · Frontiers in Physiology
  60. Targeting PP2A-dependent autophagy enhances sensitivity to ruxolitinib in JAK2V617F myeloproliferative neoplasms
    Charly Courdy, Loïc Platteeuw, Charlotte Ducau, Isabelle De Araujo, Emeline Boët, Ambrine Sahal, Estelle Saland, Valérie Edmond, Suzanne Tavitian, Sarah Bertoli et al. · 2023 · Blood Cancer Journal
  61. Early detection of anthracycline-induced cardiotoxicity
    Weimin Feng, Qingchen Wang, Yuan Tan, Jiao Qiao, Qi Liu, Boxin Yang, Shuo Yang, Yan Cui · 2024 · Clinica Chimica Acta
  62. Molecular mechanisms and biological roles of GOMED
    Saori Noguchi, Shigeomi Shimizu · 2021 · FEBS Journal
  63. Inositide-dependent signaling pathways as new therapeutic targets in myelodysplastic syndromes
    Sara Mongiorgi, Carlo Finelli, Yong Ryoul Yang, Cristina Clissa, James Andrew McCubrey, Anna Maria Billi, Lucia Manzoli, Pann‐Ghill Suh, Lucio Cocco, Matilde Y. Follo · 2015 · Expert Opinion on Therapeutic Targets
  64. PP2Ac Regulates Autophagy via Mediating mTORC1 and ULK1 During Osteoclastogenesis in the Subchondral Bone of Osteoarthritis
    Haifeng Zhang, Gaoran Ge, Wei Zhang, Houyi Sun, Xiaolong Liang, Yu Xia, Jiacheng Du, Zerui Wu, Jiaxiang Bai, Huilin Yang et al. · 2024 · Advanced Science
  65. WIPI2b recruitment to phagophores and ATG16L1 binding are regulated by ULK1 phosphorylation
    Andrea Gubaš, Eleanor Attridge, Harold B.J. Jefferies, Taki Nishimura, Minoo Razi, Simone Kunzelmann, Yuval Gilad, Thomas J. Mercer, Michael M Wilson, Adi Kimchi et al. · 2024 · EMBO Reports
  66. Nuclear Inositides and Inositide-Dependent Signaling Pathways in Myelodysplastic Syndromes
    Jie Xian, Eric Owusu Obeng, Stefano Ratti, Isabella Rusciano, Maria Vittoria Marvi, Antonietta Fazio, Alessia De Stefano, Sara Mongiorgi, Alessandra Cappellini, Giulia Ramazzotti et al. · 2020 · Cells
  67. Phosphorylation Modifications Regulating Cardiac Protein Quality Control Mechanisms
    Sumita Mishra, Brittany L Dunkerly-Eyring, Gizem Keceli, Mark John Ranek · 2020 · Frontiers in Physiology
  68. Glutamine Produces Ammonium to Tune Lysosomal pH and Regulate Lysosomal Function
    Jian Xiong, Thi Thu Trang Luu, Kartik Venkatachalam, Guangwei Du, Michael X. Zhu · 2022 · Cells
  69. Fine-Tuning of mTORC1-ULK1-PP2A Regulatory Triangle Is Crucial for Robust Autophagic Response upon Cellular Stress
    Bence Hajdú, Marianna Holczer, Gergely Horváth, Gábor Szederkényi, Orsolya Kapuy · 2022 · Biomolecules
  70. Targeting protein methylation in pancreatic cancer cells results in KRAS signaling imbalance and inhibition of autophagy
    María Fernanda Montenegro, Román Martí-Díaz, Ana Navarro, Jorge Tolivia, Luís Sánchez‐del‐Campo, Juan Cabezas‐Herrera, José Neptuno Rodríguez‐López · 2023 · Cell Death and Disease
  71. CD133-Dependent Activation of Phosphoinositide 3-Kinase /AKT/Mammalian Target of Rapamycin Signaling in Melanoma Progression and Drug Resistance
    Naji Kharouf, Thomas Wayne Flanagan, Abdulhadi A. AlAmodi, Youssef Al Hmada, Sofie-Yasmin Hassan, Hosam Shalaby, Simeon Santourlidis, Sarah-Lilly Hassan, Youssef Haïkel, Mossad Megahed et al. · 2024 · Cells
  72. Protein phosphatase 4 maintains the survival of primordial follicles by regulating autophagy in oocytes
    Ming‐Zhe Dong, Ying‐Chun Ouyang, Shi-Cai Gao, Lin‐Jian Gu, Jia-Ni Guo, Simin Sun, Zhen‐Bo Wang, Qing‐Yuan Sun · 2024 · Cell Death and Disease
  73. Autophagy inhibition by biotin elicits endoplasmic reticulum stress to differentially regulate adipocyte lipid and protein synthesis
    Senthilraja Selvam, Anand Ramaian Santhaseela, Dhasarathan Ganesan, Sudarshana Rajasekaran, Tamilselvan Jayavelu · 2019 · Cell Stress and Chaperones
  74. Shedding Light on the Role of Phosphorylation in Plant Autophagy
    Hongbo Li, Yanglan Liao, Xuanang Zheng, Xiaohong Zhuang, Caiji Gao, Jun Ma Zhou · 2022 · FEBS Letters
  75. Androgen depletion alters the diurnal patterns to signals that regulate autophagy in the limb skeletal muscle
    Michael L. Rossetti, Robert J. Tomko, Bradley Scott Gordon · 2020 · Molecular and Cellular Biochemistry
  76. PLEKHM2 deficiency induces impaired mitochondrial clearance and elevated ROS levels in human iPSC-derived cardiomyocytes
    Jianchao Zhang, Ying Peng, Wanrong Fu, Ruifei Wang, Jinhua Cao, Shuang Li, Xiaoxu Tian, Zhonggen Li, Chongpei Hua, Yafei Zhai et al. · 2024 · Cell Death Discovery
  77. Classical swine fever virus NS5A protein activates autophagy via the PP2A-DAPK3-Beclin 1 axis
    Jinfu Sun, Haixiao Yu, Yingnan Wang, Liming Li, Jinqi Zhu, Ping Ma, Zezhong Feng, Changchun Tu · 2023 · Journal of Virology
  78. Metabolic plasticity in pancreatic ductal adenocarcinoma progression and response to treatment
    Jiarui Ma, Vipul Bhardwaj, Peter Edward Lobie, Vijay Pandey · 2026 · Molecular Cancer
  79. BNIP3 enhances pancreatic cancer cell migration and proliferation via modulating autophagy under hypoxia
    Hongmei Li, Can Zhang, Qiong Zhang, Jiezhi Jia, Xiaojiao Wang · 2022 · Heliyon
  80. PAK6-mediated phosphorylation of PPP2R2C regulates LRRK2-PP2A complex formation
    Lucia Iannotta, Marco Emanuele, Giulia Favetta, Giulia Tombesi, Laurine Vandewynckel, Antonio Jesús Lara Ordóñez, Jean‐Michel Saliou, Matthieu Drouyer, William Sibran, Laura Civiero et al. · 2023 · Frontiers in Molecular Neuroscience
  81. Paternal starvation affects metabolic gene expression during zebrafish offspring development and lifelong fitness
    Ada Jiménez-González, Federico Ansaloni, Constance Nebendahl, Ghazal Alavioon, David S. Murray, Weronika Robak, Remo Sanges, Ferenc Müller, Simone Immler · 2024 · Molecular Ecology
  82. STRIPAK, a fundamental signaling hub of eukaryotic development
    Ulrich Kück, Stefanie Pöggeler · 2024 · Microbiology and Molecular Biology Reviews
  83. Downregulation of miR-338-3p alleviates neuronal ischemic injury by decreasing cPKCγ-Mediated autophagy through the Akt/mTOR pathway
    Haiping Wei, Zhifeng Peng, Jia Guo, Lixia Chen, Kangmei Shao · 2022 · Neurochemistry International
  84. Hesperetin Protects from Palmitic-Acid-Induced Lipotoxicity through the Inhibition of Glutaminolysis, mTORC1 Signaling, and Limited Apoptosis
    Wan Li, Zhengnan Cai, Florian Schindler, Martin Brenner, Christian Winter, Bianca Stiller, Petra Heffeter, Wolfram Weckwerth · 2025 · Journal of Agricultural and Food Chemistry
  85. Targeting T-type channels in cancer: What is on and what is off?
    Anna Visa, Lía Alza, Adrián Casas-Benito, Judit Herreros, Carles Cantı́ · 2021 · Drug Discovery Today
  86. Mutations at Two Key Sites in PP2A Safeguard Caenorhabditis elegans Neurons from Microcystin-LR Toxicity
    Chunhua Zhan, Jianke Gong · 2024 · Toxins
  87. The Emerging Roles of mTORC1 in Macromanaging Autophagy
    Akpedje Serena Dossou, Alakananda Basu · 2020 · Vide Leaf, Hyderabad eBooks
  88. The PP2A-B55α phosphatase is a master regulator of mitochondrial degradation and biogenesis
    Valentina Cianfanelli, Monica Nanni, Samantha Corrà, Sofia Mauri, David P. Sumpton, Sérgio Lilla, Rossella De Cegli, Matteo Bordi, Giacomo Milletti, Caterina Ferraina et al. · 2025 · Science Advances
  89. Inhibition of autophagy as a novel treatment for neurofibromatosis type 1 tumors
    Megan Stevens, Yuanli Wang, Stephanie J. Bouley, Torrey R. Mandigo, Aditi Sharma, Sonali Sengupta, Amy Housden, Oltean Sebastian, Norbert Perrimon, J.A. Walker et al. · 2024 · Molecular Oncology
  90. ODE-based models of signaling networks in autophagy
    Markus Galhuber, Kathrin Thedieck · 2024 · Current Opinion in Systems Biology
  91. p53/FBXL20 axis negatively regulates the protein stability of PR55α, a regulatory subunit of PP2A Ser/Thr phosphatase
    Lepakshe S. V. Madduri, Nichole D. Brandquist, Chitra Palanivel, Geoffrey A. Talmon, Michael J. Baine, Sumin Zhou, Charles A. Enke, Keith R. Johnson, Michel M. Ouellette, Ying Yan · 2021 · Neoplasia
  92. Autophagy regulates neuronal excitability by controlling cAMP/Protein Kinase A signaling
    Melina Overhoff, Frederik Tellkamp, S. Hess, Janine Tutas, Marianna Tolve, Marcel Faerfers, Lotte Ickert, Milad Mohammadi, Elodie De Bruyckere, Emmanouela Kallergi et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  93. Amino Acid Metabolism and Autophagy in Atherosclerotic Cardiovascular Disease
    Yuting Wu, Irem Avcilar-Kücükgöze, Donato Santovito, Dorothee Atzler · 2024 · Biomolecules
  94. IGF2BP2 stabilized by USP7 promotes cancer-associated fibroblast activation and attenuates gemcitabine sensitivity in PDAC
    Fujing Ge, Hongdao Zhu, Xiangning Liu, Yuekang Li, Runqiu Guo, Chenming Zeng, Tao Yuan, Liu Yang, Xin Dong, Yulian Wu et al. · 2025 · Cell Reports
  95. An updated outlook on autophagy mechanism and how it supports acute myeloid leukemia maintenance
    BGS Macedo, Manuela Albuquerque de Melo, Diego A. Pereira‐Martins, João Agostinho Machado‐Neto, Fabı́ola Traina · 2024 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  96. The role of autophagy in pancreatic diseases
    Wengang Zhang, Qing-Zhen Wu, Bo‐Zong Shao · 2024 · Frontiers in Pharmacology
  97. The 4-vinylcyclohexene dioxide induced mouse ovarian premature failure is caused by down regulation of IGF1R and triggering excessive autophagy
    Yuwei Niu, Yuyang Miao, Wenjing Wan, Qiankun Wang, Yingwan Ma, Meng‐Hao Pan, Baohua Ma, Qiang Wei · 2025 · Stress Biology
  98. Autophagy in Rheumatoid Arthritis: Molecular Mechanisms, Diagnostic Biomarkers, and Emerging Therapeutic Strategies
    A. Nasrollahizadeh, S. Rahmati, Mohammad Sadra Gholami Chahkand, Fatemeh Esmaeilpour Moallem, Eftekhar Azarm, P. A. Dadkhah, M. Karimi, E. Amini-Salehi, Mohammad Amin Karimi · 2026 · Inflammation
  99. Evaluating the Therapeutic Potential of MRT68921 and Afatinib in Three-Dimensional Models of Epithelial Ovarian Cancer
    Tiffany P. A. Johnston, Jack D. Webb, Matthew J. Borrelli, Emily J. Tomas, Aine Celestina Pucchio, Yudith Ramos Valdés, Trevor G. Shepherd · 2026 · Cancers
  100. Tauroursodeoxycholic Acid Confers Protection Against Oxidative Stress via Autophagy Induction in Retinal Pigment Epithelial Cells
    Daniella Zubieta, Cassandra Warden, Sujoy Bhattacharya, Milam A. Brantley · 2025 · Current Issues in Molecular Biology