Relative conduction velocities of small myelinated and non-myelinated fibres in the central nervous system
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The g-ratio is an indirect indicator of relative myelination, varies widely across axons, and scales with action propagation velocity, from approximately 0.3 m/s in small/short unmyelinated axons to more than 100 m/s in large/long myelinated fibers.
“For instance, the g-ratio (inner axonal diameter to outer fiber diameter) is an indirect indicator of relative myelination, which varies widely across axons, and scales with action propagation velocity, from approximately 0.3 m/s in small/short unmyelinated axons to more than 100 m/s in large/long myelinated fibers (Waxman & Bennett, 1972).”
From 40 Years of diffusion MRI in the brain: From history to emerging frontiers (2026) · cites this paper as Waxman & Bennett, 1972
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40 Years of diffusion MRI in the brain: From history to emerging frontiers
Le Bihan, D. (2026) · Imaging Neuroscience · doi:10.1162/imag.a.1365
“…to outer fiber diameter) is an indirect indicator of relative myelination, which varies widely across axons, and scales with action propagation velocity, from approximately 0.3 m/s in small/short unmyelinated axons to more than 100 m/s in large/long myelinated fibers ( Waxman & Bennett, 1972).”
Influential
- Authors
- WAXMAN, S. G., & BENNETT, M. V. L.
- Affiliations
- Albert Einstein College of Medicine (US)
- Venue
- Nature New Biology
- Published
- 1972-08
- Volume
- 238
- Issue
- 85
- Pages
- 217-219
- ISSN
- 0090-0028 (ISSN-L)
- 2058-1092
- OpenAlex
- W2028803857
- Cited by
- 444
- References
- 0
- Citations by year
- 2026: 8 · 2025: 22 · 2024: 14 · 2023: 18 · 2022: 16 · 2021: 17 · 2020: 23 · 2019: 14 · 2018: 38 · 2017: 17 · 2016: 14 · 2015: 14 · 2014: 14 · 2013: 8 · 2012: 8
- FWCI
- 0.97
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature New Biology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Ion channel regulation and function
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced Neuroimaging Techniques and Applications
- Keywords
- conduction velocity, myelination, myelinated axons, unmyelinated axons, axon diameter, critical diameter, central nervous system, peripheral nerves, axon morphology
- MeSH terms
- Animals, Cats, Central Nervous System, Lizards, Mathematics, Myelin Sheath, Nerve Fibers, Myelinated, Neural Conduction, Neurons, Oculomotor Nerve, Rabbits
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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