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Parallel domestication of the Shattering1 genes in cereals
Open accessAbstract
A key step during crop domestication is the loss of seed shattering. Here, we show that seed shattering in sorghum is controlled by a single gene, Shattering1 (Sh1), which encodes a YABBY transcription factor. Domesticated sorghums harbor three different mutations at the Sh1 locus. Variants at regulatory sites in the promoter and intronic regions lead to a low level of expression, a 2.2-kb deletion causes a truncated transcript that lacks exons 2 and 3, and a GT-to-GG splice-site variant in the intron 4 results in removal of the exon 4. The distributions of these non-shattering haplotypes among sorghum landraces suggest three independent origins. The function of the rice ortholog (OsSh1) was subsequently validated with a shattering-resistant mutant, and two maize orthologs (ZmSh1-1 and ZmSh1-5.1+ZmSh1-5.2) were verified with a large mapping population. Our results indicate that Sh1 genes for seed shattering were under parallel selection during sorghum, rice and maize domestication.
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Metadata
- Authors
- Lin, Z., Li, X., Shannon, L. M., Yeh, C.-T., Wang, M. L., Bai, G., Peng, Z., Li, J., Trick, H. N., Clemente, T. E., Doebley, J., Schnable, P. S., Tuinstra, M. R., Tesso, T. T., White, F., & Yu, J.
- Venue
- Nature Genetics
- Published
- 2012-05-13
- Volume
- 44
- Issue
- 6
- Pages
- 720-724
- ISSN
- 1061-4036 (ISSN-L)
- 1546-1718
- OpenAlex
- W2065668692
- Cited by
- 459
- References
- 0
- FWCI
- 14.17
- Type
- journal article
- Language
- en
- Open access
- green
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- Lin, Z., Li, X., Shannon, L. M., Yeh, C.-T., Wang, M. L., Bai, G., Peng, Z., Li, J., Trick, H. N., Clemente, T. E., Doebley, J., Schnable, P. S., Tuinstra, M. R., Tesso, T. T., White, F., & Yu, J. (2012). Parallel domestication of the Shattering1 genes in cereals. Nature Genetics. https://doi.org/10.1038/ng.2281
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