Mapping cis- and trans-regulatory effects across multiple tissues in twins

The Multiple Tissue Human Expression Resource (MuTHER) Consortium, Grundberg, Elin, Small, Kerrin S, Hedman, Åsa K, Nica, Alexandra C, Buil, Alfonso, Keildson, Sarah, Bell, Jordana T +44 more·2012·Nature Genetics

DOI 10.1038/ng.2394

Cited by (748)

Items 501–600 of 748

Protein Phosphatase 1 Regulatory Subunit 3B Genotype at rs4240624 Has a Major Effect on Gallbladder Bile Composition
Ville Männistö, Dorota Kamińska, Pirjo Käkelä, Mikko Neuvonen, Mikko Niemi, Marcus Alvarez, Päivi Pajukanta, Stefano Romeo, Max Nieuwdorp, Albert Kornelis Groen et al. · 2020 · Hepatology Communications
Joint eQTL assessment of whole blood and dura mater tissue from individuals with Chiari type I malformation
Eric F. Lock, Karen L. Soldano, Melanie E. Garrett, Heidi Cope, Christina A. Markunas, Herbert E. Fuchs, Gerald Arthur Grant, David B. Dunson, Simon G. Gregory, Allison E. Ashley‐Koch · 2015 · BMC Genomics
Dynamics of Brain Structure and its Genetic Architecture over the Lifespan
R. Brouwer, M. Klein, K. Grasby, H. Schnack, N. Jahanshad, J. Teeuw, S. Thomopoulos, E. Sprooten, C. Franz, N. Gogtay et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
Adipose tissue eQTL meta-analysis reveals the contribution of allelic heterogeneity to gene expression regulation and cardiometabolic traits
Sarah M. Brotman, Julia S. El-Sayed Moustafa, Li Guan, K. Alaine Broadaway, Dongmeng Wang, Anne Jackson, Ryan Welch, Kevin W. Currin, Max Tomlinson, Swarooparani Vadlamudi et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
Allelic Switching of DLX5, GRB10, and SVOPL during Colorectal Cancer Tumorigenesis
Arnoud Boot, Jan Oosting, Saskia Doorn, Sarah Ouahoud, Marina Ventayol García, Dina Ruano, Hans M. Morreau, Tom van Wezel · 2019 · International Journal of Genomics
Common Variants Associated With OSMR Expression Contribute to Carotid Plaque Vulnerability, but Not to Cardiovascular Disease in Humans
Daniëlle van Keulen, Ian D. van Koeverden, Arjan Boltjes, Hans M. G. Princen, Alain J. van Gool, Gert Jan de Borst, Folkert Wouter Asselbergs, Dennie Tempel, Gerard Pasterkamp, Sander W. van der Laan · 2021 · Frontiers in Cardiovascular Medicine
Twins and omics: the role of twin studies in multi-omics
Fiona A. Hagenbeek, Jenny van Dongen, René Pool, Dorret Irene Boomsma · 2022 · Elsevier eBooks
Cumulative evidence for associations between genetic variants in interleukin 17 family gene and risk of human diseases
Tianyu Liu, Lei Yang, Xiaolong Lv, Chunjian Zuo, Chenhao Jia, Zelin Yang, Chongqi Fan, Huanwen Chen · 2022 · Frontiers in Immunology
Revealing the architecture of genetic and epigenetic regulation: a maximum likelihood model
F. Wang, S. Zhang, Y. Wen, Y. Wei, Han Yan, Hui Liu, Jianzhong Su, Yan Zhang, J. Che · 2013 · Briefings in Bioinformatics
Combination of mouse models and genomewide association studies highlights novel genes associated with human kidney function
Jiaojiao Jing, Cristian Pattaro, Anselm Hoppmann, Yukinori Okada, Caroline S. Fox, Anna Köttgen · 2016 · Kidney International
Incomplete penetrance: The role of stochasticity in developmental cell colonization
Benjamin James Binder, Kerry Anne Landman, Donald F. Newgreen, Joshua V. Ross · 2015 · Journal of Theoretical Biology
Transcriptome outlier analysis implicates schizophrenia susceptibility genes and enriches putatively functional rare genetic variants
Jubao Duan, Alan R. Sanders, Winton Moy, Eugene I. Drigalenko, Eric C. Brown, Jessica Freda, Catherine Leites, Harald H.H. Göring, MGS, Pablo V. Gejman · 2015 · Human Molecular Genetics
MiRNA-Related Genetic Variations Associated with Radiotherapy-Induced Toxicities in Patients with Locally Advanced Non–Small Cell Lung Cancer
Rong Li, Xia Pu, Joe Yujiao Chang, Yuanqing Ye, Ritsuko U Komaki, John Dorrance Minna, Jack A. Roth, Baohui Han, Xifeng Wu · 2016 · PLoS ONE
Lymphoblastoid Cell Lines as a Tool to Study Inter-Individual Differences in the Response to Glucose
Michael A. Grassi, Vidhya R. Rao, Siquan Chen, Dingcai Cao, Xiaoyu Gao, Patricia A. Cleary, R. Stephanie Huang, Andrew D. Paterson, Rama D Natarajan, Jalees Rehman et al. · 2016 · PLoS ONE
Deciphering the coordinated roles of the host genome, duodenal mucosal genes, and microbiota in regulating complex traits in chickens
Fang-Ren Lan, Xi-Qiong Wang, Qianqian Zhou, Xiao-Chang Li, Jiaming Jin, Wenxin Zhang, Chao-Liang Wen, Gui-Qin Wu, Guang-Qi Li, Yi-Yuan Yan et al. · 2025 · Microbiome
Sparse multi-view matrix factorization: a multivariate approach to multiple tissue comparisons
Zi Wang, Wei Yuan, Giovanni Montana · 2015 · Bioinformatics
Human Genomics in Cardiovascular Medicine
Hiroyuki Morita · 2013 · Circulation Journal
Genetic variants in matrix metalloproteinase genes as disposition factors for ovarian cancer risk, survival, and clinical outcome
Yan Wang, Yuanqing Ye, Jie Ming Lin, Larissa Alejandra Meyer, Xifeng Wu, Karen H. Lu, Dong Liang · 2013 · Molecular Carcinogenesis
GenoExp: a web tool for predicting gene expression levels from single nucleotide polymorphisms
Ohad Manor, Eran Segal · 2015 · Bioinformatics
Analytical tools to assess aging in humans: The rise of geri-omics
João Pinto da Costa, Teresa Rocha‐Santos, Armando C. Duarte · 2015 · TrAC Trends in Analytical Chemistry
C-src tyrosine kinase gene rs1378942 polymorphism and hypertension in Asians: Review and meta-analysis
Xinling Qian, Yuqian Li, Xiaotian Liu, Runqi Tu, Zhongyan Tian, Haiqing Zhang, Xia Zhang, Wen Zhou, Jingjing Jiang, Yanhua Wang et al. · 2018 · Clinica Chimica Acta
Joint eQTL mapping and inference of gene regulatory network improves power of detecting both cis - and trans -eQTLs
Xin Hua Zhou, Xiaodong Cai · 2021 · Bioinformatics
Genetic architecture of tuberculosis susceptibility: A comprehensive research synopsis, meta-analyses, and epidemiological evidence
Lin Jiao, Jiajia Song, Hao Chen, Dongqing Gu, Shun Liao, Juan Zhou, Tao Wu, Jingwei Zhang, Xuejiao Lina Hu, Hao Bai et al. · 2022 · Infection Genetics and Evolution
Robust Linear Models for Cis-eQTL Analysis
Mattias Rantalainen, Cecilia M. Lindgren, Chris C. Holmes · 2015 · PLoS ONE
A powerful approach reveals numerous expression quantitative trait haplotypes in multiple tissues
Dingge Ying, Mulin Jun Li, Pak Chung Sham, Miaoxin Li · 2018 · Bioinformatics
Expression QTLs Mapping and Analysis: A Bayesian Perspective
Martha Imprialou, Enrico G. Petretto, Leonardo Bottolo · 2016 · Methods in molecular biology
Sequence variant affects GCSAML splicing, mast cell specific proteins, and risk of urticaria
Ragnar P. Kristjansson, Gudjon R. Oskarsson, A. Skuladóttir, A. Oddsson, S. Rognvaldsson, G. Sveinbjornsson, S. Lund, B. Jensson, Edda L. Styrmisdottir, G. Halldorsson et al. · 2023 · Communications Biology
RTeQTL: Real-Time Online Engine for Expression Quantitative Trait Loci Analyses
Baoshan Ma, Jian Jun Huang, Liming Liang · 2014 · Database
Intersection of genetics and epigenetics in monozygotic twin genomes
Kwoneel Kim, Kibaick Lee, Hyoeun Bang, Jeong Yeon Kim, Jung Kyoon Choi · 2015 · Methods
Selected heterozygosity at cis-regulatory sequences increases the expression homogeneity of a cell population in humans
Min Kyung Sung, Juneil Jang, Kang Seon Lee, Cheol-Min Ghim, Jung Kyoon Choi · 2016 · Genome biology
Transcriptome Profiling in Rat Inbred Strains and Experimental Cross Reveals Discrepant Genetic Architecture of Genome-Wide Gene Expression
Pamela J. Kaisaki, Georg Otto, Karène Argoud, Stephan C. Collins, Robert H. Wallis, Steven P. Wilder, Anthony C. Y. Yau, Christophe Hue, Sophie Caldérari, Marie‐Thérèse Bihoreau et al. · 2016 · G3 Genes Genomes Genetics
Genome-wide integrative analysis identified SNP-miRNA-mRNA interaction networks in peripheral blood mononuclear cells
Xiang Lin, Wei Xia, Wei Ji, Fangfei Xie, Pei He, Xiao-Wei Zhu, Yonghong Zhang, Fei‐Yan Deng, Shu‐Feng Lei · 2017 · Epigenomics
Genetic variation at the microRNA binding site of CAV1 gene is associated with lung cancer susceptibility
Xue Fang, Xuelian Li, Zhihua Yin, Lingzi Xia, Xiaowei Quan, Yuxia Zhao, Baosen Zhou · 2017 · Oncotarget
Viewpoint: Toward the Genetic Architecture of Disease Severity in Inflammatory Bowel Diseases
Claire Liefferinckx, Denis Paul Franchimont · 2018 · Inflammatory Bowel Diseases
A polyclonal allelic expression assay for detecting regulatory effects of transcript variants
Margot K. Brandt, Alper Gokden, Marcello Ziosi, Tuuli Lappalainen · 2020 · Genome Medicine
The contributions of mitochondrial and nuclear mitochondrial genetic variation to neuroticism
Charley Xia, Sarah J. Pickett, David C M Liewald, Alexander Weiß, Gavin Hudson, William David Hill · 2023 · Nature Communications
Effects of copy number variable regions on local gene expression in white blood cells of Mexican Americans
August N. Blackburn, Marcio Almeida, Angela K Dean, Joanne E. Curran, Matthew P. Johnson, Eric Keith Moses, Lawrence J. Abraham, Melanie A. Carless, Thomas D. Dyer, Satish Kumar et al. · 2015 · European Journal of Human Genetics
A mutation in a splicing factor that causes retinitis pigmentosa has a transcriptome-wide effect on mRNA splicing
Paul K Korir, Lisa J. Roberts, Raj Ramesar, Cathal Seoighe · 2014 · BMC Research Notes
Population‐specific genome‐wide mapping of expression quantitative trait loci in the colon of Han Chinese
Chang Cun Guo, Wei Ni, Shu Liang, Biao Luo Wang, Su Mei Sha, Kaichun Wu · 2016 · Journal of Digestive Diseases
Expression Quantitative Trait Loci (eQTL) Analysis in Cancer
Yaoming Liu, Youqiong Ye, Jing Gong, Leng Han · 2019 · Methods in molecular biology
Using regulatory variants to detect gene–gene interactions identifies networks of genes linked to cell immortalisation
David Wragg, Q. Liu, Z. Lin, Valentina Riggio, Carys Pugh, A. J. Beveridge, Helen K. Brown, David Arthur Hume, Sarah E. Harris, Ian J. Deary et al. · 2020 · Nature Communications
Variant-to-function approaches for adipose tissue: Insights into cardiometabolic disorders
Sophia Metz, Jonathan Robert Belanich, Melina Claussnitzer, Tuomas O. Kilpeläinen · 2025 · Cell Genomics
OmiGA for ultra-efficient molecular quantitative trait loci mapping
Jinyan Teng, Wenjing Zhang, Wentao Gong, Jiajian Chen, Yahui Gao, Lingzhao Fang, Zhe Zhang · 2026 · Nature Communications
Polymorphisms in ERCC4 and ERCC5 and risk of cancers: Systematic research synopsis, meta-analysis, and epidemiological evidence
Chunjian Zuo, Xiaolong Lv, Tianyu Liu, Lei Yang, Zelin Yang, Yu Cao, Huanwen Chen · 2022 · Frontiers in Oncology
Germline immunomodulatory expression quantitative trait loci (ieQTLs) associated with immune-related toxicity from checkpoint inhibition
Robert Ferguson, Vylyny Chat, Leah J. Morales, Danny Simpson, Kelsey R. Monson, Elisheva Cohen, Sarah Zusin, Gabriele Madonna, Mariaelena Capone, Ester Simeone et al. · 2023 · European Journal of Cancer
Links between melanoma germline risk loci, driver genes and comorbidities: insight from a tissue‐specific multi‐omic analysis
Michael Pudjihartono, Evgeniia Golovina, Tayaza Fadason, Justin Martin O'Sullivan, William S. Schierding · 2024 · Molecular Oncology
Informing disease modelling with brain-relevant functional genomic annotations
Regina Hertfelder Reynolds, John Hardy, Mina Ryten, Sarah A. Gagliano Taliun · 2019 · Brain
Heritability jointly explained by host genotype and microbiome: will improve traits prediction?
Denis Awany, Emile R. Chimusa · 2020 · Briefings in Bioinformatics
Trans -acting genetic variation affects the expression of adjacent genes
Krisna Van Dyke, Sheila Lutz, Gemechu Mekonnen, Chad L. Myers, Frank Wolfgang Albert · 2021 · Genetics
New Insights Into Mitochondrial Dysfunction at Disease Susceptibility Loci in the Development of Type 2 Diabetes
Hannah Maude, Winston Lau, Nikolas Maniatis, Toby Andrew · 2021 · Frontiers in Endocrinology
Single-nuclei chromatin profiling of ventral midbrain reveals cell identity transcription factors and cell-type-specific gene regulatory variation
Yujuan Gui, Kamil Grzyb, Mélanie H. Thomas, Jochen Ohnmacht, Pierre Garcia, Manuel Buttini, Alexander Skupin, Thomas Sauter, Lasse Sinkkonen · 2021 · Epigenetics & Chromatin
Large-scale analysis of circulating glutamate and adipose gene expression in relation to abdominal obesity
Ina Maltais‐Payette, Jinchu Vijay, Marie-Michelle Simon, Jacques Corbeil, Francis Brière, Elin Grundberg, André Tchernof · 2022 · Amino Acids
Peripheral gene interactions define interpretable clusters of core ASD genes in a network-based investigation of the omnigenic theory
Ábel Fóthi, Csaba Pintér, Péter Pollner, András Lörincz · 2022 · npj Systems Biology and Applications
Genomic expression differences between cutaneous cells from red hair color individuals and black hair color individuals based on bioinformatic analysis
Joan Anton Puig‐Butillé, Pol Giménez‐Xavier, Alessia Visconti, Jérémie Nsengimana, Francisco Garcia‐García, Gemma Tell‐Martí, Maria Jose Escamez, Julia Newton‐Bishop, Veronique A. Bataille, Marcela Del Río et al. · 2016 · Oncotarget
ABCG2 regulatory single-nucleotide polymorphisms alter in vivo enhancer activity and expression
Rachel J. Eclov, Mee J. Kim, Aparna Chhibber, Robin P. Smith, Nadav Ahituv, Deanna L. Kroetz · 2017 · Pharmacogenetics and Genomics
Identification of New Genes and Loci Associated With Bone Mineral Density Based on Mendelian Randomization
Yijun Liu, Guang Jin, Xue Wang, Ying Dong, Fupeng Ding · 2021 · Frontiers in Genetics
A novel variant associated with HDL-C levels by modifying DAGLB expression levels: An annotation-based genome-wide association study
Dan Zhou, Dandan Zhang, Xiaohui Sun, Zhiqiang Li, Yaqin Ni, Zhongyan Shan, Hong Li, Chengguo Liu, Shuai Zhang, Yi Liu et al. · 2018 · European Journal of Human Genetics
Diverse environmental perturbations reveal the evolution and context-dependency of genetic effects on gene expression levels
Amanda J. Lea, Julie Peng, Julien F. Ayroles · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
Tensor-FLAMINGO unravels the complexity of single-cell spatial architectures of genomes at high-resolution
Hao Wang, Jiaxin Yang, Xinrui Yu, Yu Zhang, Jianliang Qian, Jianrong Wang · 2025 · Nature Communications
Identifying genetic regulatory variants that affect transcription factor activity
Xiaoting Li, Tuuli Lappalainen, Harmen J. Bussemaker · 2023 · Cell Genomics
Statistical Methods for Drug Discovery
Max Kühn, Phillip D. Yates, Craig L Hyde · 2016 · Statistics for biology and health
A general framework for predicting the transcriptomic consequences of non-coding variation and small molecules
Moustafa Abdalla, Mohamed Abdalla, Mark I. McCarthy, Chris C. Holmes · 2022 · PLoS Computational Biology
Transcriptome-wide association studies associated with Crohn’s disease: challenges and perspectives
Keyu Jia, Jun Shen · 2024 · Cell & Bioscience
Genetic influences on nicotinic α5 receptor (CHRNA5) CpG methylation and mRNA expression in brain and adipose tissue
Jessica E. Ramsay, C. Harker Rhodes, Keerthi Thirtamara Rajamani, Ryan M. Smith · 2015 · Genes and Environment
Influences of Gestational Obesity on Associations between Genotypes and Gene Expression Levels in Offspring following Maternal Gastrointestinal Bypass Surgery for Obesity
Frédéric Guénard, Maxime Lamontagne, Yohan Bossé, Yves Deshaies, Katherine Cianflone, John G. Kral, Picard Marceau, Marie‐Claude Vohl · 2015 · PLoS ONE
Chromosome 16q22 variants in a region associated with cardiovascular phenotypes correlate with ZFHX3expression in a transcript-specific manner
Ruairidh I.R. Martin, William Andrew Owens, Michael S. Cunnington, Bongani M. Mayosi, Mauro Santibanez‐Koref, Bernard D. Keavney · 2014 · BMC Genetics
Quantitative Trait Loci Identify Functional Noncoding Variation in Cancer
Holger Heyn · 2016 · PLoS Genetics
Pathway analysis of expression-related SNPs on genome-wide association study of basal cell carcinoma
Xin Li, Liming Liang, Immaculata De Vivo, Jean Yuh Tang, Jiali Han · 2016 · Oncotarget
Immunomodulatory germline variation associated with the development of multiple primary melanoma (MPM)
Robert Ferguson, Alexi N. Archambault, Danny Simpson, Leah J. Morales, Vylyny Chat, Esther Kazlow, Rebecca Lax, Garrett H. Yoon, Una Moran, Richard L. Shapiro et al. · 2019 · Scientific Reports
Leveraging auxiliary data from arbitrary distributions to boost GWAS discovery with Flexible cFDR
Anna Hutchinson, Guillermo Reales, Thomas W. Willis, Chris Wallace · 2021 · PLoS Genetics
Using clustering of genetic variants in Mendelian randomization to interrogate the causal pathways underlying multimorbidity
Xiaoran Liang, Ninon Mounier, Nicolas Apfel, Sara Khalid, Timothy M. Frayling, Jack Bowden · 2023 · medRxiv
Identification of asthma-related genes using asthmatic blood eQTLs of Korean patients
Dong Jun Kim, Ji Eun Lim, Hae‐Un Jung, Ju Yeon Chung, Eun Ju Baek, Hyein Jung, Shin Young Kwon, Han‐Kyul Kim, Ji‐One Kang, Kyungtaek Park et al. · 2023 · BMC Medical Genomics
Familial resemblances in human whole blood transcriptome
Bénédicte L. Tremblay, Frédéric Guénard, Benoı̂t Lamarche, Louis Përusse, Marie‐Claude Vohl · 2018 · BMC Genomics
HLA-G Polymorphisms Are Associated with Non-Segmental Vitiligo among Brazilians
Luciana Caricati Veiga-Castelli, Maria Luiza Guimarães de Oliveira, Álison Luís Eburnêo Pereira, Guilherme Debortoli, Letícia Marcorin, N. C. A. Fracasso, Guilherme Silva, Andréia S. Souza, Juliana Doblas Massaro, Aguinaldo Luíz Simões et al. · 2019 · Biomolecules
Integrating rare variant genetics and brain transcriptome data implicates novel schizophrenia putative risk genes
Shengtong Han, Marieke R. Gilmartin, Wenhui Sheng, Victor X. Jin · 2025 · Schizophrenia Research
Linking polymorphic p53 response elements with gene expression in airway epithelial cells of smokers and cancer risk
Xuting Wang, Gary S. Pittman, Omari J. Bandele, Jason J. Bischof, Gang Liu, John F. Brothers, Avrum E. Spira, Douglas A. Bell · 2014 · Human Genetics
Genetic Variation Is the Major Determinant of Individual Differences in Leukocyte Endothelial Adhesion
Michael A. Grassi, Vidhya R. Rao, Kathryn P. Winkler, Wei Zhang, Joseph D. Bogaard, Siquan Chen, Bonnie L. LaCroix, Divya Lenkala, Jalees Rehman, Asrar B. Malik et al. · 2014 · PLoS ONE
PopPAnTe: population and pedigree association testing for quantitative data
Alessia Visconti, Mashael Nedham Al-Shafai, Wadha Al‐Muftah, Shaza B. Zaghlool, Massimo Mangino, Karsten Suhre, Mario Falchi · 2017 · BMC Genomics
Germline genetic host factors as predictive biomarkers in immuno-oncology
Vylyny Chat, Robert Ferguson, Tomas Kirchhoff · 2019 · Immuno-Oncology Technology
Enhancer polymorphisms at the IKZF1 susceptibility locus for acute lymphoblastic leukemia impact B-cell proliferation and differentiation in both Down syndrome and non-Down syndrome genetic backgrounds
Vincent Ulysses Gant, Jacob J. Junco, Maci Terrell, Raushan Rashid, Karen R. Rabin · 2021 · PLoS ONE
Shared associations identify causal relationships between gene expression and immune cell phenotypes
Christiane Gasperi, Sung Chun, Shamil R. Sunyaev, Chris J. Cotsapas · 2021 · Communications Biology
Characterization of Expression Quantitative Trait Loci in Pedigrees from Colombia and Costa Rica Ascertained for Bipolar Disorder
Christine B. Peterson, Susan K. Service, Anna J. Jasinska, Fuying Gao, Ivette Zelaya, Terri M. Teshiba, Carrie E. Bearden, Rita M. Cantor, Victor I. Reus, Gabriel Macaya et al. · 2016 · PLoS Genetics
The Pharmacoepigenomics Informatics Pipeline Defines a Pathway of Novel and Known Warfarin Pharmacogenomics Variants
Ari Allyn-Feuer, Alex S. Ade, Jasmine A. Luzum, Gerald A. Higgins, Brian D Athey · 2018 · Pharmacogenomics
Quantifying the degree of sharing of genetic and non-genetic causes of gene expression variability across four tissues
Alfonso Buil, Ana Viñuela, Andrew Anand Brown, Matthew N Davies, Ismaël Padioleau, Deborah Bielser, Luciana Romano, Daniel Glass, Paola Di Meglio, Kerrin S. Small et al. · 2016 · bioRxiv (Cold Spring Harbor Laboratory)
Constraint and divergence of global gene expression in the mammalian embryo
Noah Spies, Cheryl L. Smith, Jesse M. Rodriguez, Julie C. Baker, Serafim Batzoglou, Arend Sidow · 2015 · eLife
Genetic Variants Contributing to Colistin Cytotoxicity: Identification of TGIF1 and HOXD10 Using a Population Genomics Approach
Michael T. Eadon, Ronald J. Hause, Amy L. Stark, Ying‐Hua Cheng, Heather E. Wheeler, Kimberly Burgess, Eric A. Benson, Patrick N. Cunningham, Robert L. Bacallao, Pierre C. Dagher et al. · 2017 · International Journal of Molecular Sciences
Computational Problems in Multi-tissue Models of Health and Disease
Manikandan Narayanan · 2017 · Journal of the Indian Institute of Science
Trans-eQTLs identified in whole blood have limited influence on complex disease biology
Chloe X. Yap, Luke R. Lloyd‐Jones, Alexander Holloway, Peter Smartt, Naomi R. Wray, Jacob Gratten, Joseph E. Powell · 2018 · European Journal of Human Genetics
Inferred expression regulator activities suggest genes mediating cardiometabolic genetic signals
Jason W. Hoskins, Charles C. Chung, Aidan O’Brien, Jun Zhong, Katelyn E. Connelly, Irene J. Collins, Jianxin Shi, Laufey Thora Amundadottir · 2021 · PLoS Computational Biology
SNPs in FAM13A and IL2RB genes are associated with FeNO in adult subjects with asthma
Simone Accordini, Valentina Lando, Lucia Calciano, Cristina Bombieri, Giovanni Malerba, Antonino Margagliotti, Cosetta Minelli, James Potts, Diana A. van der Plaat, Mario Olivieri · 2023 · Journal of Breath Research
Differential promoter activity by nucleotide substitution at a type 2 diabetes genome‐wide association study signal upstream of the wolframin gene
Jihye Ryu, Chaeyoung Lee · 2015 · Journal of Diabetes
Improved estimation of SNP heritability using Bayesian multiple-phenotype models
Najla Saad Elhezzani · 2018 · European Journal of Human Genetics
Winner’s curse correction and variable thresholding improve performance of polygenic risk modeling based on genome-wide association study summary-level data
Jianxin Shi, Ju-Hyun Park, Jubao Duan, Sonja I. Berndt, Winton Moy, Kai Yu, Lei Song, William Wheeler, Xing Hua, Debra T. Silverman et al. · 2016 · bioRxiv (Cold Spring Harbor Laboratory)
Leveraging functional annotation to identify genes associated with complex diseases
Wei Liu, Mo Li, Wenfeng Zhang, Geyu Zhou, Xing Wu, Jiawei Wang, Qiongshi Lu, Hongyu Zhao · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
The nature of sex differences in catecholamine-induced lipolysis in subcutaneous fat cells
Lucas Massier, Daniel Peter Andersson, Nathalie Viguerie, Jiawei Zhong, Danae Zareifi, Alastair G. Kerr, Dominique Langin, Peter Arner · 2025 · iScience
rs2072135, a low‐penetrance variant for chronic lymphocytic leukaemia?
Georgina P. Sava, Helen E. Speedy, Maria Chiara Di Bernardo, Silvia Deaglio, Lidia Karabon, Irena Frydecka, Dariusz Woszczyk, Davide Rossi, Gianluca Gaïdano, Larry Mansouri et al. · 2013 · British Journal of Haematology
Transmembrane Protein 187 (TMEM187) and Interleukin 1 Receptor Associated Kinase (IRAK1) gene polymorphism association with rheumatoid arthritis susceptibility in Egyptian patients
Heba Zaghloul, Sanaa Abdelshafy, Enas Aboelkheir Abdelaleem, Hala Ali, Rasha Khattab · 2023 · Egyptian journal of Immunology
Accounting for isoform expression increases power to identify genetic regulation of gene expression
Nathan LaPierre, Harold Pimentel · 2024 · PLoS Computational Biology
The statistical practice of the GTEx Project: from single to multiple tissues
Xu Liao, Xiaoran Chai, Xingjie Shi, Lin Chen, Jin Liu · 2020 · Quantitative Biology
Twin studies in inherited eye disease
Abhishek Nag, Christopher J. Hammond · 2013 · Clinical and Experimental Ophthalmology