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Cited by 335

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia

Open access
Lan, Qing, Hsiung, Chao A, Matsuo, Keitaro, Hong, Yun-Chul, Seow, Adeline, Wang, Zhaoming, Hosgood, H Dean, Chen, Kexin, Wang, Jiu-Cun, Chatterjee, Nilanjan, Hu, Wei, Wong, Maria Pik, Zheng, Wei, Caporaso, Neil, Park, Jae Yong, Chen, Chien-Jen, Kim, Yeul Hong, Kim, Young Tae, Landi, Maria Teresa, Shen, Hongbing, Lawrence, Charles, Burdett, Laurie, Yeager, Meredith, Yuenger, Jeffrey, Jacobs, Kevin B, Chang, I-Shou, Mitsudomi, Tetsuya, Kim, Hee Nam, Chang, Gee-Chen, Bassig, Bryan A, Tucker, Margaret, Wei, Fusheng, Yin, Zhihua, Wu, Chen, An, She-Juan, Qian, Biyun, Lee, Victor Ho Fun, Lu, Daru, Liu, Jianjun, Jeon, Hyo-Sung, Hsiao, Chin-Fu, Sung, Jae Sook, Kim, Jin Hee, Gao, Yu-Tang, Tsai, Ying-Huang, Jung, Yoo Jin, Guo, Huan, Hu, Zhibin, Hutchinson, Amy, Wang, Wen-Chang, Klein, Robert, Chung, Charles C, Oh, In-Jae, Chen, Kuan-Yu, Berndt, Sonja I, He, Xingzhou, Wu, Wei, Chang, Jiang, Zhang, Xu-Chao, Huang, Ming-Shyan, Zheng, Hong, Wang, Junwen, Zhao, Xueying, Li, Yuqing, Choi, Jin Eun, Su, Wu-Chou, Park, Kyong Hwa, Sung, Sook Whan, Shu, Xiao-Ou, Chen, Yuh-Min, Liu, Li, Kang, Chang Hyun, Hu, Lingmin, Chen, Chung-Hsing, Pao, William, Kim, Young-Chul, Yang, Tsung-Ying, Xu, Jun, Guan, Peng, Tan, Wen, Su, Jian, Wang, Chih-Liang, Li, Haixin, Sihoe, Alan Dart Loon, Zhao, Zhenhong, Chen, Ying, Choi, Yi Young, Hung, Jen-Yu, Kim, Jun Suk, Yoon, Ho-Il, Cai, Qiuyin, Lin, Chien-Chung, Park, In Kyu, Xu, Ping, Dong, Jing, Kim, Christopher, He, Qincheng, Perng, Reury-Perng, Kohno, Takashi, Kweon, Sun-Seog, Chen, Chih-Yi, Vermeulen, Roel, Wu, Junjie, Lim, Wei-Yen, Chen, Kun-Chieh, Chow, Wong-Ho, Ji, Bu-Tian, Chan, John K C, Chu, Minjie, Li, Yao-Jen, Yokota, Jun, Li, Jihua, Chen, Hongyan, Xiang, Yong-Bing, Yu, Chong-Jen, Kunitoh, Hideo, Wu, Guoping, Jin, Li, Lo, Yen-Li, Shiraishi, Kouya, Chen, Ying-Hsiang, Lin, Hsien-Chih, Wu, Tangchun, Wu, Yi-Long, Yang, Pan-Chyr, Zhou, Baosen, Shin, Min-Ho, Fraumeni, Joseph F, Lin, Dongxin, Chanock, Stephen J, Rothman, Nathaniel·2012·Nature Genetics
DOI 10.1038/ng.2456
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Abstract

To identify common genetic variants that contribute to lung cancer susceptibility, we conducted a multistage genome-wide association study of lung cancer in Asian women who never smoked. We scanned 5,510 never-smoking female lung cancer cases and 4,544 controls drawn from 14 studies from mainland China, South Korea, Japan, Singapore, Taiwan and Hong Kong. We genotyped the most promising variants (associated at P < 5 × 10−6) in an additional 1,099 cases and 2,913 controls. We identified three new susceptibility loci at 10q25.2 (rs7086803, P = 3.54 × 10−18), 6q22.2 (rs9387478, P = 4.14 × 10−10) and 6p21.32 (rs2395185, P = 9.51 × 10−9). We also confirmed associations reported for loci at 5p15.33 and 3q28 and a recently reported finding at 17q24.3. We observed no evidence of association for lung cancer at 15q25 in never-smoking women in Asia, providing strong evidence that this locus is not associated with lung cancer independent of smoking.

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Authors
Lan, Q., Hsiung, C. A., Matsuo, K., Hong, Y.-C., Seow, A., Wang, Z., Hosgood, H. D., Chen, K., Wang, J.-C., Chatterjee, N., Hu, W., Wong, M. P., Zheng, W., Caporaso, N., Park, J. Y., Chen, C.-J., Kim, Y. H., Kim, Y. T., Landi, M. T., Shen, H., Lawrence, C., Burdett, L., Yeager, M., Yuenger, J., Jacobs, K. B., Chang, I.-S., Mitsudomi, T., Kim, H. N., Chang, G.-C., Bassig, B. A., Tucker, M., Wei, F., Yin, Z., Wu, C., An, S.-J., Qian, B., Lee, V. H. F., Lu, D., Liu, J., Jeon, H.-S., Hsiao, C.-F., Sung, J. S., Kim, J. H., Gao, Y.-T., Tsai, Y.-H., Jung, Y. J., Guo, H., Hu, Z., Hutchinson, A., Wang, W.-C., Klein, R., Chung, C. C., Oh, I.-J., Chen, K.-Y., Berndt, S. I., He, X., Wu, W., Chang, J., Zhang, X.-C., Huang, M.-S., Zheng, H., Wang, J., Zhao, X., Li, Y., Choi, J. E., Su, W.-C., Park, K. H., Sung, S. W., Shu, X.-O., Chen, Y.-M., Liu, L., Kang, C. H., Hu, L., Chen, C.-H., Pao, W., Kim, Y.-C., Yang, T.-Y., Xu, J., Guan, P., Tan, W., Su, J., Wang, C.-L., Li, H., Sihoe, A. D. L., Zhao, Z., Chen, Y., Choi, Y. Y., Hung, J.-Y., Kim, J. S., Yoon, H.-I., Cai, Q., Lin, C.-C., Park, I. K., Xu, P., Dong, J., Kim, C., He, Q., Perng, R.-P., Kohno, T., Kweon, S.-S., Chen, C.-Y., Vermeulen, R., Wu, J., Lim, W.-Y., Chen, K.-C., Chow, W.-H., Ji, B.-T., Chan, J. K. C., Chu, M., Li, Y.-J., Yokota, J., Li, J., Chen, H., Xiang, Y.-B., Yu, C.-J., Kunitoh, H., Wu, G., Jin, L., Lo, Y.-L., Shiraishi, K., Chen, Y.-H., Lin, H.-C., Wu, T., Wu, Y.-L., Yang, P.-C., Zhou, B., Shin, M.-H., Fraumeni, J. F., Lin, D., Chanock, S. J., & Rothman, N.
Venue
Nature Genetics
Publisher
Springer Science and Business Media LLC
Published
2012-11-11
Volume
44
Issue
12
Pages
1330-1335
ISSN
  • 1061-4036 (ISSN-L)
  • 1546-1718
DOI
10.1038/ng.2456
OpenAlex
W2049330354
Cited by
335
References
6
FWCI
17.72
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia. https://app.cochat.ai/papers/10.1038/ng.2456
The paper
Lan, Q., Hsiung, C. A., Matsuo, K., Hong, Y.-C., Seow, A., Wang, Z., Hosgood, H. D., Chen, K., Wang, J.-C., Chatterjee, N., Hu, W., Wong, M. P., Zheng, W., Caporaso, N., Park, J. Y., Chen, C.-J., Kim, Y. H., Kim, Y. T., Landi, M. T., . . . Rothman, N. (2012). Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia. Nature Genetics. https://doi.org/10.1038/ng.2456

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.