The deleterious mutation load is insensitive to recent population history.

Simons, Yuval B, Turchin, Michael C, Pritchard, Jonathan K, Sella, Guy·2014·Nature Genetics

Cited by (279)

Items 201–279 of 279

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  16. The landscape of fitness effects of putatively functional noncoding mutations in humans
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  17. Gene flow from the European wild apple and selection shaped the domesticated apple genome
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  25. Exact calculation of the joint allele frequency spectrum for isolation with migration models
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  43. Spectrum of Neandertal introgression across modern-day humans indicates multiple episodes of human-Neandertal interbreeding
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  44. Allele surfing causes maladaptation in a Pacific salmon of conservation concern
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  45. Estimating genetic load from 5000 Chinese exomes.
    Xiao-Shuai Du, Xiaoxi Zhang, Jiu-Cun Wang, Li Jin, Shu-Hua Xu · 2025 · Journal of genetics and genomics = Yi chuan xue bao
  46. Purging of deleterious variants due to drift and founder effect in Italian populations with extended autozygosity
    Massimiliano Cocca, Marc Pybus, Pier Francesco Palamara, Erik P. Garrison, Michela Traglia, Cinzia Felicita Sala, Sheila Uiivi, Yasin Memari, Anja Kolb‐Kokocinski, Shane McCarthy et al. · 2015 · bioRxiv (Cold Spring Harbor Laboratory)
  47. Carga genética por efeito carona sob diferentes regimes seletivos no genoma humano
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  48. Authors’ Reply to Letter to the Editor: Neutral genetic diversity as a useful tool for conservation biology
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  49. Human deleterious mutation rate slows adaptation and implies high fitness variance
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  50. The pattern and distribution of deleterious mutations in maize
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  52. Title: The role of deleterious substitutions in crop genomes
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  53. Molecular Genetics and Population Genomics of the Maintenance and Breakdown of the Floral Polymorphism Tristyly
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  56. Using Rare Genetic Variation to Understand Human Demography and the Etiology of Complex Traits.
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  57. Probing the aggregated effects of purifying selection per individual on 1,380 medical phenotypes in the UK biobank
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  58. What HaveWe Learned fromGWAS?
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  59. Faculty Opinions recommendation of Ultrarare variants drive substantial cis heritability of human gene expression.
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