Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

Go-T2D Consortium, Flannick, Jason, T2D-GENES Consortium, Thorleifsson, Gudmar, Beer, Nicola L, Jacobs, Suzanne B R, Grarup, Niels, Burtt, Noël P +74 more·2014·Nature Genetics
DOI 10.1038/ng.2915

Cited by (491)

Items 301–400 of 491

  1. Genetic Architecture of Type 2 Diabetes
    Rashmi B. Prasad, Leif Groop · 2016 · Wiley eBooks
  2. Royaume du Maroc
    Benhima · 1962 · Présence Africaine
  3. Electrophysiological Characterization of Inducible Pluripotent Stem Cell–Derived Human β-Like Cells and an SLC30A8 Disease Model
    Manon Jaffredo, Nicole A. J. Krentz, Benoite Champon, Claire E. Duff, Sameena Nawaz, Nicola L. Beer, Christian Honoré, Anne Clark, Patrik Rorsman, Jochen Lang et al. · 2024 · Diabetes
  4. "Diabetes Associated Genes from the Dark Matter of the Human Proteome"
    Ramaswamy Narayanan · 2014 · MOJ Proteomics & Bioinformatics
  5. Structural Insight on GPR119 Agonist as Potential Therapy for Type II Diabetes: A Comprehensive Review
    Priyanshu Nema, Vivek Asati, Priyadarshi Kendya, Twinkle Gupta, Shivangi Agarwal, Shivam Kumar Kori, Varsha Kashaw, Arun K. Iyer, Sushil K. Kashaw · 2023 · Mini-Reviews in Medicinal Chemistry
  6. Cohort profile: SUPER-Finland – the Finnish study for hereditary mechanisms of psychotic disorders
    Markku Lähteenvuo, Ari Ahola‐Olli, Kimmo Suokas, Minna Torniainen‐Holm, Zuzanna Misiewicz, Tuomas Jukuri, Teemu Männynsalo, Asko Wegelius, Willehard Haaki, Risto Kajanne et al. · 2023 · BMJ Open
  7. A null mutation in ANGPTL8 does not associate with either plasma glucose or type 2 diabetes in humans
    Katharine R. Clapham, Audrey Y. Chu, Jennifer Wessel, Pradeep Natarajan, Jason A. Flannick, Manuel A. Rivas, Samantha Sartori, Roxana Mehran, Usman Baber, Valentı́n Fuster et al. · 2016 · BMC Endocrine Disorders
  8. Is zinc an intra-islet regulator of glucagon secretion?
    H. Ishihara, C. Wollheim · 2016 · Diabetology International
  9. Genetic Polymorphisms and Zinc Status: Implications for Supplementation in Metabolic Diseases
    Fabio Virgili, Roberto Ambra, Jacqueline M. McCormack, Ellen E. A. Simpson, Donatella Ciarapica, Lorenzo Barnaba, Elena Azzini, Angela Polito · 2018 · Current Pharmaceutical Design
  10. Review of How Genetic Research on Segmental Progeroid Syndromes Has Documented Genomic Instability as a Hallmark of Aging But Let Us Now Pursue Antigeroid Syndromes !
    George M. Martin, Fuki Marie Hisama, Junko Oshima · 2020 · The Journals of Gerontology Series A
  11. Next Generation Exome Sequencing of Pediatric Asthma Identifies Rare and Novel Variants in Candidate Genes
    Neda M. Bogari, Amr A. Amin, Husni H. Rayes, Ahmed Abdelmotelb, Mohiuddin M. Taher, Faisal Ahmad Al-Allaf, Abdellatif Bouazzaoui, Luke O’Gorman, John W. Holloway · 2021 · Disease Markers
  12. Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation
    Natasha Hui Jin Ng, Sara M. Willems, Juan Fernandez, Rebecca S. Fine, Eleanor Wheeler, Jennifer Wessel, Hidetoshi Kitajima, Gaëlle Marenne, Jana K. Rundle, Xueling Sim et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  13. Lack of ZnT8 protects pancreatic islets from hypoxia- and cytokine induced cell death
    Maria Karsai, Richard A. Zuellig, Roger Lehmann, Federica Cuozzo, Daniela Nasteska, Edlira Luca, Constanze Hantel, David J. Hodson, Giatgen A. Spinas, Guy A. Rutter et al. · 2022 · Zurich Open Repository and Archive (University of Zurich)
  14. The role of metallothionein-3 in streptozotocin-induced beta-islet cell death and diabetes in mice
    Hyae-Ran Byun, Jeong A Choi, Jae‐Young Koh · 2014 · Metallomics
  15. Genetic mutations you want
    Sarah C. P. Williams · 2016 · Proceedings of the National Academy of Sciences
  16. Diabetes in Population Isolates: Lessons from Greenland
    Niels Grarup, Ida Moltke, Anders Albrechtsen, Torben F. Hansen · 2015 · The Review of Diabetic Studies
  17. ZnT8 Haploinsufficiency Impacts MIN6 Cell Zinc Content and β-Cell Phenotype via ZIP-ZnT8 Coregulation
    Rebecca Lawson, Wolfgang Maret, Christer Högstrand · 2019 · International Journal of Molecular Sciences
  18. Pathogenesis of Type 2 Diabetes Mellitus
    Ralph Anthony DeFronzo · 2018 · Endocrinology
  19. Emerging Biomarkers and Nanobiosensing Strategies in Diabetes
    Anupriya Baranwal, Vipul Bansal, Ravi Shukla · 2025 · Biosensors
  20. Prioritization of genes associated with type 2 diabetes mellitus for functional studies
    Wei Xuan Tan, Xueling Sim, Chin Meng Khoo, Adrian Kee Keong Teo · 2023 · Nature Reviews Endocrinology
  21. Beta cell specific ZnT8 gene deficiency and resulting loss in zinc content significantly improve insulin secretion.
    A. Piro, Yihan Luo, Ziyi Zhang, Wenyue W Ye, Fei Kang, Xie Li, Yufeng Wang, F. Dai, H. Gaisano, J. Rocheleau et al. · 2024 · Molecular and Cellular Endocrinology
  22. Complete loss of SLC30A8 in humans improves glucose metabolism and beta cell function
    Lindsey B. Lamarche, Christopher Koch, Shareef Khalid, Maleeha Zaman Khan, Richard Zessis, Matthew E. Clement, Daniel P. Denning, Allison B. Goldfine, Igor Splawski, Ali Abbasi et al. · 2025 · Diabetologia
  23. Metal transport mechanism of the cation diffusion facilitator (CDF) protein family – a structural perspective on human CDF (ZnT)-related diseases
    Shiran Barber-Zucker, Arie Moran, Raz Zarivach · 2021 · RSC Chemical Biology
  24. Regulation of divalent metal ions to the aggregation and membrane damage of human islet amyloid polypeptide oligomers
    Yajie Wang, Feihong Meng, Tong Lu, Chunyun Wang, Fei Li · 2021 · RSC Advances
  25. ZnT8 Loss of Function Mutation Increases Resistance of Human Embryonic Stem Cell-Derived Beta Cells to Apoptosis in Low Zinc Condition
    Lina Sui, Qian Du, Anthony I. Romer, Qi Su, PAULINE L. CHABOSSEAU, Yurong Xin, Jinrang Kim, Sandra Kleiner, Guy A. Rutter, Dieter M. Egli · 2023 · Cells
  26. New Therapies for Coronary Artery Disease: Genetics Provides a Blueprint
    Daniel James Rader · 2014 · Science Translational Medicine
  27. Differential burden of rare protein truncating variants in Alzheimer’s disease patients compared to centenarians
    Yun Freudenberg‐Hua, Wentian Li, Avinash Abhyankar, Vladimir Vacic, Vanessa Rodrigues Paixão Côrtes, Danny Ben‐Avraham, Jeremy L. Koppel, BLAINE S. GREENWALD, Søren Germer, Robert B. Darnell et al. · 2016 · Human Molecular Genetics
  28. Bench Research Informed by GWAS Results
    Nikolay V. Kondratyev, М. В. Алфимова, Arkadiy K. Golov, Вера Евгеньевна Голимбет · 2021 · Cells
  29. Human pancreatic α-cell heterogeneity and trajectory inference analyses reveal SMOC1 as a β-cell dedifferentiation gene
    Randy B. Kang, Miguel Varela, Eunjin Oh, Jung Eun Lee, Tuo Zhang, Esra Karaköse, Andrew F. Stewart, Donald K. Scott, Debbie C. Thurmond, Adolfo Garcı́a-Ocaña et al. · 2025 · Nature Communications
  30. Single-nucleus multi-omics identifies shared and distinct pathways in Pick’s and Alzheimer’s disease
    Zechuan Shi, Sudeshna Das, Samuel Morabito, Jennifer T. Stocksdale, Emily Miyoshi, Shushrruth Sai Srinivasan, Nora Emerson, Arshi Shahin, Negin Rahimzadeh, Zhenkun Cao et al. · 2025 · Science Advances
  31. Genetic propensities for verbal and spatial ability have opposite effects on body mass index and risk of schizophrenia
    Guðrún A. Jónsdóttir, Guðmundur Einarsson, Guðmar Þorleifsson, Sigurður H. Magnússon, Arni F. Gunnarsson, Michael L. Frigge, Rósa S. Gísladóttir, Unnur Unnsteinsdóttir, Bjarni Gunnarsson, G. Bragi Walters et al. · 2021 · Intelligence
  32. Unraveling the potential effects of non-synonymous single nucleotide polymorphisms (nsSNPs) on the Protein structure and function of the human SLC30A8 gene on type 2 diabetes and colorectal cancer: An In silico approach
    Mohammed Majbah Uddin, Md. Tanvir Hossaın, Md. Arju Hossain, Asif Ahsan, Kamrul Hasan Shamim, Md. Arif Hossen, Md. Shahinur Rahman, Md Habibur Rahman, Kawsar Ahmed, Francis Minhthang Bui et al. · 2024 · Heliyon
  33. Genomic-based tools for the risk assessment, management, and prevention of type 2 diabetes
    Katherine Johansen Taber, Barry D. Dickinson · 2015 · The Application of Clinical Genetics
  34. Genetics: Finding Genes for Schizophrenia
    Jonathan Flint C, Marcus Robert Munafo · 2014 · Current Biology
  35. Genetic markers and continuity of healthy metabolic status: Tehran cardio-metabolic genetic study (TCGS)
    Omid Gharooi Ahangar, Niloufar Javanrouh, MARYAM SADAT DANESHPOUR, Maryam Barzin, Majid Valizadeh, Fereidoun Azizi, Farhad Hosseinpanah · 2020 · Scientific Reports
  36. Evidence that Evolution of the Diabetes Susceptibility Gene SLC30A8 that Encodes the Zinc Transporter ZnT8 Drives Variations in Pancreatic Islet Zinc Content in Multiple Species
    Karin J. Bosma, Kristen E. Syring, James K. Oeser, Jason D. Lee, Richard K.P. Benninger, Matthew Edward Pamenter, Richard M. O’Brien · 2019 · Journal of Molecular Evolution
  37. Diabetes and Renin-Angiotensin-Aldosterone System: Pathophysiology and Genetics
    A.H.M. Nurun Nabi, Akio Ebihara · 2021 · IntechOpen eBooks
  38. Zinc–rs13266634 and the Arrival of Diabetes Pharmacogenetics: The “Zinc Mystique”
    Nisa M. Maruthur, Braxton D. Mitchell · 2014 · Diabetes
  39. C-Terminal Domain of the Human Zinc Transporter hZnT8 Is Structurally Indistinguishable from Its Disease Risk Variant (R325W)
    Raheem Ullah, Aamir Shehzad, Majid Ali Shah, Matteo De March, Fouzia Ismat, Mazhar Iqbal, Silvia Onesti, Moazur Rahman, Michael J. McPherson · 2020 · International Journal of Molecular Sciences
  40. Haploinsufficiency of the NF1 gene is associated with protection against diabetes
    Roope A. Kallionpää, Sirkku A. Peltonen, Jussi Leppävirta, Minna Pöyhönen, Kari J. Auranen, Hannu Järveläinen, Juha T.K. Peltonen · 2020 · Journal of Medical Genetics
  41. Genetics and erectile dysfunction: leveraging early foundations for new discoveries
    Darshan P. Patel, Alexander W. Pastuszak, James Morris Hotaling · 2020 · International Journal of Impotence Research
  42. Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization
    Sara M. Willems, Natasha Hui Jin Ng, Juan Fernandez, Rebecca S. Fine, Eleanor Wheeler, Jennifer Wessel, Hidetoshi Kitajima, Gaëlle Marenne, Xueling Sim, Hanieh Yaghootkar et al. · 2023 · Wellcome Open Research
  43. Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing ( IWGT )
    Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long et al. · 2024 · Environmental and Molecular Mutagenesis
  44. Understanding the Genetic Landscape of Gestational Diabetes: Insights into the Causes and Consequences of Elevated Glucose Levels in Pregnancy
    Caroline Brito Nunes, Maria Carolina Borges, Rachel M. Freathy, Debbie A. Lawlor, Elisabeth Qvigstad, David M. Evans, Gunn-Helen Moen · 2024 · Metabolites
  45. Zrt-Irt-like Proteins (ZIP) Family Zinc Transporters: Emerging Players in Pancreatic β Cell Function and Insulin Regulation
    Samuel Blake Mitchell, Tolunay Beker Aydemir · 2025 · Journal of Nutrition
  46. Zinc Transporters in Diseases, Including Diabetes and Related Conditions
    Wenjun Xu, Xuan Wang, Yukun Gao, Qing Ma, Weida Li · 2025 · Physiology
  47. High-throughput synthetic rescue for exhaustive characterization of suppressor mutations in human genes
    Farah Kobaisi, Nour Fayyad, Eric Sulpice, Bassam M. Badran, Hussein Fayyad‐Kazan, Walid Rachidi, Xavier Gidrol · 2020 · Cellular and Molecular Life Sciences
  48. Genetic Determinism in the Post-Genomic Age
    Marc A. T. Muskavitch · 2014 · Integritas Advancing the Mission of Catholic Higher Education
  49. Lack of Association betweenSLC30A8Variants and Type 2 Diabetes in Mexican American Families
    Hemant R. Kulkarni, Manju Mamtani, Juan M. Peralta, Vincent P. Diego, Thomas D. Dyer, Harald H.H. Göring, Laura A. Almasy, Michael C. Mahaney, Sarah Williams‐Blangero, Ravindranath Duggirala et al. · 2016 · Journal of Diabetes Research
  50. Target discovery using biobanks and human genetics
    Michael A. Hicks, Claire Hou, Arya Iranmehr, Krisztina Marosi, Ewen F. Kirkness · 2019 · Drug Discovery Today
  51. Whole-exome sequencing in familial type 2 diabetes identifies an atypical missense variant in the RyR2 gene
    Vikas Bansal, Bernhard Rudolf Winkelmann, Johannes W. Dietrich, Bernhard Otto Boehm · 2024 · Frontiers in Endocrinology
  52. Association of the IGF1 gene with fasting insulin levels
    Sara M. Willems, Belinda K. Cornes, Jennifer A. Brody, Alanna C. Morrison, Leonard Lipovich, Marco Dauriz, Yuning Chen, Ching‐Ti Liu, Denis V. Rybin, Richard A. Gibbs et al. · 2016 · European Journal of Human Genetics
  53. Zinc Transporters in Health and Disease
    Taiho Kambe, Yukina Nishito, Kazuhisa Fukue · 2016 · Elsevier eBooks
  54. Two novel susceptibility loci for type 2 diabetes mellitus identified by longitudinal exome-wide association studies in a Japanese population
    Yoshiki Yasukochi, Jun Sakuma, Ichiro Takeuchi, Kimihiko Kato, Mitsutoshi Oguri, Tetsuo Fujimaki, Hideki Horibe, Yoshiji Yamada · 2017 · Genomics
  55. Gene silencing of ZnT8 attenuates inflammation and protects pancreatic tissue injury in T1D
    Hong Sun, Cunyu Li, Shufa Li, Xunhua Li, Jinguang Wang, Zhongqi Zhou, Mingtao Shao · 2018 · Immunology Letters
  56. Type 2 diabetes mellitus and zinc dysregulation: From basic and epidemiological evidence to interventions
    Irene Martínez-Morata, Kathryn Dennehy, Oleg G. Chepurny, Tuncay Delibaşı, Kathrin Schilling, Ana Navas‐Acién, Malek El Muayed · 2025 · Journal of Trace Elements in Medicine and Biology
  57. Human gain-of-function MC4R variants show signaling bias and protect against obesity
    Luca Andrea Lotta, Jacek Mokrosiński, Mendes de Oliveira E, Chao Li, Sharp Sj, Jian’an Luan, Bas Brouwers, Vikram Ayinampudi, Nicholas Bowker, Nicola D. Kerrison et al. · 2020 · Yearbook of pediatric endocrinology
  58. Impact of an SLC30A8 loss-of-function variant on the pancreatic distribution of zinc and manganese: laser ablation-ICP-MS and positron emission tomography studies in mice
    George Firth, Eleni Georgiadou, Alex Griffiths, Maral Amrahli, Jana Kim, Zilin Yu, Ming Hu, Theodora J. Stewart, Isabelle Leclerc, Haruka Okamoto et al. · 2023 · Frontiers in Endocrinology
  59. Towards the recognition of oligogenic forms of type 2 diabetes
    Lauriane Le Collen, Philippe Froguel, Amélie Bonnefond · 2024 · Trends in Endocrinology and Metabolism
  60. Zinc Transport Gets Its Zing Back: Double-Knockout of ZnT7 and ZnT8 Reveals the Importance of Zinc Transporters to Insulin Secretion
    Craig S. Nunemaker, Richard K.P. Benninger · 2016 · Endocrinology
  61. Informing Prevention and Intervention Policy Using Genetic Studies of Resistance
    Brion S. Maher, Shawn J. Latendresse, Michael M. Vanyukov · 2016 · Prevention Science
  62. The Diabetes Susceptibility Gene SLC30A8 that Encodes the Zinc Transporter ZnT8 is a Pseudogene in Guinea Pigs Potentially Contributing to Low Guinea Pig Islet Zinc Content
    Kristen E. Syring, Karin J. Bosma, James K. Oeser, Masakazu Shiota, Richard M. O’Brien · 2018 · Journal of Molecular Evolution
  63. Machine learning reveals connections between preclinical type 2 diabetes subtypes and brain health
    Yi Fan, Jing Yuan, Fei Han, Judith Somekh, Mor Peleg B, Fei Ling Wu, Zhilong Jia, Yi‐Cheng Zhu, Zhengxing Huang · 2025 · Brain
  64. Nonsense Mutations in Eukaryotes
    Nadezhda A. Potapova · 2022 · Biochemistry (Moscow)
  65. The role of protective genetic variants in modulating epigenetic aging
    Yosra Bejaoui, Luma Srour, Abeer Qannan, Junko Oshima, Chadi Saad, Steve Horvath, Hamdi Mbarek, Nady El Hajj · 2025 · GeroScience
  66. Inference Methods for Multiple Merger Coalescents
    Bjarki Eldon · 2016 · Springer eBooks
  67. Genomics reveals eleven obesity endotypes with distinct biological and phenotypic signatures
    Min Seo Kim, Minku Song, Hoyoung Kim, Sanghyeon Park, Injeong Shim, Soo‐Hyun Lim, Beomsu Kim, Xingyu Chen, Yang Sui, So Mi Jemma Cho et al. · 2025 · medRxiv
  68. Zinc accumulation-induced integrated stress response triggers β-cell identity loss
    Qing Ma, Wenjun Xu, Xuan Wang, Haoyu Nie, Yukun Gao, Rui Hu, Zhihao Yang, Xushu Wang, Ta Na, X. Chen et al. · 2026 · Cell Research
  69. A Compound Screen Based on Isogenic hESC‐Derived β Cell Reveals an Inhibitor Targeting ZnT8‐Mediated Zinc Transportation to Protect Pancreatic β Cell from Stress‐Induced Cell Death
    Rui Hu, Qing Ma, Yunhui Kong, Zhaoyue Wang, Minglu Xu, Xiangyi Chen, Yajuan Su, Tinghui Xiao, Qing Hua He, Xuan Wang et al. · 2025 · Advanced Science
  70. Accelerating Medicines Partnership in Type 2 Diabetes and Common Metabolic Diseases: Collaborating to Maximize the Value of Genetic and Genomic Data
    Maria C. Costanzo, Beena Akolkar, Melina Claussnitzer, José C. Florez, Anna L. Gloyn, Struan F.A. Grant, Klaus H. Kaestner, Alisa Knodle Manning, Karen L. Mohlke, Stephen C.J. Parker et al. · 2025 · Diabetes
  71. DNA and RNA Molecules as a Foundation of Therapy Strategies for Treatment of Cardiovascular Diseases
    Ljiljana B. Rakicevic · 2023 · Pharmaceutics
  72. Development of a live cell assay for the zinc transporter ZnT8
    Lucia Azzollini, Dolores Del Prete, Gernot Wolf, Christoph Klimek, Mattia Saggioro, Fernanda Ricci, Eirini Christodoulaki, Tabea Wiedmer, Álvaro Inglés‐Prieto, Giulio Superti‐Furga et al. · 2024 · SLAS DISCOVERY
  73. A double knockout for zinc transporter 8 and somatostatin in mice reveals their distinct roles in regulation of insulin secretion and obesity
    Zhongyue Yang, Catherine P. Kirschke, Yimeng Cai, Liping Huang · 2024 · Genes & Nutrition
  74. Decoding the Genetic Blueprint: Advancing Personalized Medicine in Type 2 Diabetes through Pharmacogenomics
    Shambo Samrat Samajdar, Anuj Maheshwari, Ajoy Tiwari, Shatavisa Mukherjee, Kaushik Biswas, Banshi Saboo, Anup Rawool, Shashank Joshi · 2024 · Clinical Diabetology
  75. Collaborative science in the next-generation sequencing era: a viewpoint on how to combine exome sequencing data across sites to identify novel disease susceptibility genes
    Steven N. Hart, Kara N. Maxwell, Tinu Thomas, Vignesh Ravichandran, Bradley Wubberhorst, Robert J. Klein, Kasmintan A. Schrader, Csilla Szabo, Jeffrey N. Weitzel, Susan L. Neuhausen et al. · 2015 · Briefings in Bioinformatics
  76. The State of Whole-Genome Sequencing
    Andrew Dervan, Jay Shendure · 2016 · Elsevier eBooks
  77. Genetics of Endocrinology
    Amit R. Majithia, David Altshuler, Joel N. Hirschhorn · 2016 · Elsevier eBooks
  78. Mapping of Susceptibility Genes for Obesity, Type 2 Diabetes, and the Metabolic Syndrome in Human Populations
    Rector Arya, Sobha Puppala, Vidya S. Farook, Geetha Chittoor, Christopher P. Jenkinson, John Blangero, Daniel Esten Hale, Ravindranath Duggirala, Laura A. Almasy · 2015 · Springer eBooks
  79. Genetics of Diabetes and Diabetic Complications
    Rashmi B. Prasad, Emma Ahlqvist, Leif Groop · 2018 · Endocrinology
  80. Functional insights into dispensable genes using genome-wide loss-of-function burden tests in Arabidopsis
    Kehan Zhao, Mariele Lensink, J. Grey Monroe · 2026 · The Plant Cell
  81. Metal‐dependent regulated cell death: Molecular architecture and translational frontiers
    Haoliang Hu, Zhe Chen, Yaqi Li, Jiayi Peng, Jiangang Cao, Hong Zhou, Mengqi Wang, Yuejia Du, H Wu, Huiqin Zhao et al. · 2026 · iMeta
  82. In silico identification and wet lab validation of novel cryptic B cell epitopes in ZnT8 zinc transporter autoantigen
    Sugumar Shruthi, Viswanathan Mohan, Muralidhara Rao Maradana, Vivekanandhan Aravindhan · 2019 · International Journal of Biological Macromolecules
  83. Genetic inactivation of zinc transporter SLC39A5 improves liver function and hyperglycemia in obesogenic settings
    Shek Man Chim, Kristen Howell, John Dronzek, Weizhen Wu, Cristopher V. Van Hout, Manuel A. R. Ferreira, Bin Ye, Alexander H. Li, Susannah D. Brydges, Arunachalam Vinayagam et al. · 2024 · eLife
  84. Allelic Expression Imbalance: Tipping the Scales to Elucidate the Function of Type 2 Diabetes–Associated Loci
    Shana Erin McCormack, Struan F.A. Grant · 2015 · Diabetes
  85. Encode, Decode and Diabetes
    Gumpeny Ramachandra Sridhar · 2017 · SpringerBriefs in applied sciences and technology
  86. Obesity, diabetes and zinc: A workshop promoting knowledge and collaboration between the UK and Israel, november 28–30, 2016 – Israel
    Alicia Josephine Jenkins, Imre Lengyel, Guy A. Rutter, Nicola M. Lowe, Iris Shai, Amir Tirosh, Tünde Pető, Mogher Khamaisi, Simon Colin Andrews, Niv Zmora et al. · 2018 · Journal of Trace Elements in Medicine and Biology
  87. Could personalised risk prediction for type 2 diabetes using polygenic risk scores direct prevention, enhance diagnostics, or improve treatment?
    Mathilde Boecker, Alvina Grace Lai · 2020 · Wellcome Open Research
  88. Genetics of Type 2 Diabetes
    Struan F.A. Grant · 2015 · Springer eBooks
  89. ER Stress, Secretory Granule Biogenesis, and Insulin
    Michiko Saito, Yoko Shiba · 2019 · IntechOpen eBooks
  90. Genetics of Type 2 Diabetes
    Struan F.A. Grant · 2016 · Springer eBooks
  91. The Role of Pharmacogenomics in Diabetes
    Y. W. Francis Lam, Ravindranath Duggirala, Christopher P. Jenkinson, Rector Arya · 2019 · Elsevier eBooks
  92. The Role of Genetic Interactions in Neurodevelopmental Disorders
    Jason H. Moore, Kevin J. Mitchell · 2015 · Wiley eBooks
  93. Genetic discovery and translational decision support from exome sequencing of 20,791 type 2 diabetes cases and 24,440 controls from five ancestries
    J. Flannick, J. Mercader, C. Fuchsberger, M. Udler, A. Mahajan, J. Wessel, T. Teslovich, Lizz Caulkins, Ryan Koesterer, T. Blackwell et al. · 2018 · bioRxiv
  94. RNA inosine sensor-guided TadA mutational scanning for toxicity minimization of adenine base editors
    Cheng Zhang, Ziliang Chen, Jixin Cao, Zui Zhang, Wei-Ke Li, Xinyi Zhang, Junying Chen, Jun Liu, Zhou Yuan, Feng Gao et al. · 2025 · Molecular Therapy
  95. African-enriched SLC39A10 (ZIP10) missense variants differentially affect cellular zinc homeostasis and associate with health-related traits
    Jee-Oo Song, Seebon Cho, Juyoung Kim, Kaixiong Ye, Moon‐Suhn Ryu · 2026 · Genes & Nutrition
  96. SLC30A8: A Complex Road from Association to Function
    Jason A. Flannick, William L. Lowe · 2016 · Springer eBooks
  97. Urinary metal profiles in mother-offspring pairs and their association with early dysglycemia in the International Hyperglycemia and Adverse Pregnancy Outcome Follow Up Study (HAPO-FUS)
    Malek El Muayed, Janice C. Wang, Winifred P.S. Wong, Boyd E. Metzger, Katelyn B. Zumpf, Miranda G. Gurra, Rebecca A. Sponenburg, M. Geoffrey Hayes, Denise M. Scholtens, Lynn P. Lowe et al. · 2022 · Journal of Exposure Science & Environmental Epidemiology
  98. Genetic outline of the hermeneutics of the diseases connection phenomenon in human
    Elena Yu. Bragina, Valery Pavlovich Puzyrev · 2023 · Vavilov Journal of Genetics and Breeding
  99. Protective effect of the rare variant rs13266634C/T of the SLC30A8 gene in the genetic background of the development of type 2 diabetes in Turkish population
    Dudu Erkoç Kaya, Hilal Arıkoğlu, Muslu Kazım Körez, Süleyman Hilmi İpekçi, Süleyman Baldane · 2023 · International Journal of Diabetes in Developing Countries
  100. Diabetes Mellitus: Exploring Biomarkers, Complications, and Therapeutic Strategies with a Spotlight on Cyanobacterial Bioactive Compounds - A Comprehensive Review
    Suhail Ahmad, Salman Akhtar, Mohammad Amjad Kamal, Alvina Farooqui · 2024 · Current Diabetes Reviews