TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for neurokinin B in the central control of reproduction

Topaloglu, A Kemal, Reimann, Frank, Guclu, Metin, Yalin, Ayse Serap, Kotan, L Damla, Porter, Keith M, Serin, Ayse, Mungan, Neslihan O +7 more·2009·Nature Genetics
DOI 10.1038/ng.306

Cited by (951)

Items 901–951 of 951

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  15. The Hypothalamus-Pituitary in Males in Health and Disease
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  16. Nonneoplastic diseases of the testis
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  17. Precocious Puberty in Girls: Pathogenesis, Genetic Architecture and Emerging Molecular Therapies
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  18. De novo rare EMX2 variants lead to idiopathic hypogonadotropic hypogonadism
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  19. Additional file 1 of Insights into the genetics of menopausal vasomotor symptoms: genome-wide analyses of routinely-collected primary care health records
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  24. Genetic Basis and Heterogeneity of Congenital Hypogonadotropic Hypogonadism
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  25. Relationship between kisspeptin-10, neurokinin B and dynorphin A in the course of normal and delayed puberty in ewes
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  33. Inactivating PLEKHA6 Mutations Cause Idiopathic Hypogonadotropic Hypogonadism Through Impaired Kisspeptin Secretion
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  36. Identification of a Novel Splice-Site variant in TACR3 (c.888 + 1G > A) Associated with Asthenozoospermia and Hypogonadotropic Hypogonadism in an Iranian Family
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  39. Genetic landscape of a neonatal hypogonadotropic hypogonadism series: Novel variants and phenotypic spectrum
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  45. BindingDB Entry 50044734: Development of novel neurokinin 3 receptor (NK3R) selective agonists with resistance to proteolytic degradation.
    BindingDB · 2016 · UC San Diego
  46. BindingDB Entry 50042856: Structure-activity relationship study of tachykinin peptides for the development of novel neurokinin-3 receptor selective agonists.
    BindingDB · 2013 · UC San Diego
  47. BindingDB Entry 50040855: Identification of a crucial amino acid in the helix position 6.51 of human tachykinin neurokinin 1 and 3 receptors contributing to the insurmountable mode of antagonism by dual NK1/NK3 antagonists.
    BindingDB · 2013 · UC San Diego
  48. BindingDB Entry 50045788: Discovery and optimization of novel antagonists to the human neurokinin-3 receptor for the treatment of sex-hormone disorders (Part I).
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  49. The developmental, genetic, and epigenetic basis of polyendocrine metabolic ovarian syndrome
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  50. Pathway-Specific Signaling and its Impact on Fertility: A Focus on the Kisspeptin Receptor, Kiss1r
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  51. Ipogonadismo ipogonadotropo familiare isolato e mutazione del gene GNRH1
    Jérôme Bouligand, Cristina Ghervan, Javier Ananda Tello, Sylvie Brailly‐Tabard, Sylvie Salenave, Philippe Chanson, Marc Lombès, Robert Peter Millar, Anne Guiochon‐Mantel, Jacques Young et al. · 2009 · L Endocrinologo