Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer

Makohon-Moore, Alvin P, Zhang, Ming, Reiter, Johannes G, Bozic, Ivana, Allen, Benjamin, Kundu, Deepanjan, Chatterjee, Krishnendu, Wong, Fay +12 more·2017·Nature Genetics

DOI 10.1038/ng.3764

Cited by (411)

Items 301–400 of 411

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Benedict Kinny‐Köster, Yembur Ahmad, Michael Johannes Pflüger, Joseph R. Habib, Kohei Fujikura, Danielle Hutchings, John L. Cameron, Christopher R. Shubert, Kelly J. Lafaro, Richard Andrew Burkhart et al. · 2024 · Pancreas
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Alexander Ioannis Damanakis, Florian Gebauer, Christiane J. Bruns · 2020 · Der Chirurg
Evolutionary Dynamics of Non-Coding Regions in Pancreatic Ductal Adenocarcinoma
Akimasa Hayashi, Yu-Jui Ho, Alvin P. Makohon-Moore, Amanda Zucker, Jungeui Hong, Johannes G. Reiter, Jinlong Huang, Lance Zhang, Marc A. Attiyeh, Priscilla Baez et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
Ongoing Replication Stress Response and New Clonal T Cell Development Discriminate Between Liver and Lung Recurrence Sites and Patient Outcomes in Pancreatic Ductal Adenocarcinoma
Jason M. Link, Carl Pelz, Patrick Joseph Worth, Sydney Owen, Dove Keith, Ellen M. Langer, Alison Grossblatt-Wait, Allison Creason, Julian Egger, Hannah D. Holly et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
Convergence for Inactivation of TGFβ Signaling Is a Common Feature of Advanced Pancreatic Cancer
Jungeui Hong, Zachary A. Kohutek, Haochen Zhang, Nicolas Lecomte, Elias-Ramzey R. Karnoub, Rajya L. Kappagantula, Laura DeLong Wood, Eileen Mary O'Reilly, Marsha Reyngold, Christopher H. Crane et al. · 2026 · Cancer Discovery
CRISPR screen of human pancreatic cancer xenografts identifies a KLF5 proliferation vulnerability through epigenetic modifiers NCAPD2 and MTHFD1
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Clonal evolutionary analysis reveals patterns of malignant transformation of Intraductal Papillary Mucinous Neoplasms of the pancreas
Antonio Pea, Xiaotong T. He, Rosie Upstill-Goddard, Claudio Luchini, Leonor Patricia Schubert Santana, Stephan B. Dreyer, Fraser Duthie, Nigel Balfour Jamieson, Colin J. McKay, Euan J. Dickson et al. · 2026 · Nature Communications
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Viktor Hlaváč, Beatrice Mohelníková-Duchoňová, Martin Loveček, Jiří Ehrmann, Veronika Brynychová, Katerina Kolarova, Pavel Souček · 2020 · Genes
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Xia Tang, Lei Xiang, Qingshu Li, Yue Shao, Li Wan, Dachun Zhao, Xiaoyuan Li, Songfeng Wu, Haijian Wang, Dewei Li et al. · 2023 · Hepatology International
The COMPASS complex maintains the metastatic capacity imparted by a subpopulation of cells in UPS
Ga I Ban, Vijitha Puviindran, Xiang Yu, Puvi Nadesan, Yuning J. Tang, Jianhong Ou, Nicholas J. Guardino, Makoto Nakagawa, MaKenna R. Browne, Asjah Wallace et al. · 2024 · iScience
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Vasiliki Liaki, Blanca Rosas-Pérez, Carmen E. Guerra · 2025 · Cancers
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Lesley Paige Ferguson, David Arthur Tuveson · 2025 · Annual Review of Cancer Biology
Identification of a robust functional subpathway signature for pancreatic ductal adenocarcinoma by comprehensive and integrated analyses
Ping Wang, Chunlong Zhang, Weidong Li, Bo Zhai, Xian Li Jiang, Shiva Reddy, Hongchi Jiang, Xueying Sun · 2020 · Cell Communication and Signaling
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Katerina Dukleska, Charles J. Yeo, Michael Jon Pishvaian, Jonathan Robert Brody · 2018 · Springer eBooks
The Role of Epigenetics in Pancreatic Ductal Adenocarcinoma
Marcus T. T. Roalsø, Øyvind H. Hald, Daniel Ansari, Roland E. Andersson, Kjetil Søreide · 2021 · Springer eBooks
Circulating Tumor Cells
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BASIC SCIENCE IN ONCOLOGY: YEAR 2017 OVERVIEW
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Shamim Sarhadi, Ali Salehzadeh‐Yazdi, Mehdi Damaghi, Nosratollah Zarghami, Olaf Wolkenhauer A, Hedayatollah Hosseini · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
MYC controls metastatic heterogeneity in pancreatic cancer
Ravikanth Maddipati, Robert J. Norgard, Timour Baslan, Komal S. Rathi, Amy Xin Wei Zhang, Pichai Raman, Jason Robert Pitarresi, Maximilian D. Wengyn, Taiji Yamazoe, Jinyang Li et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
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Ankit Shukla, Raja Kalayarasan, Pothugunta Sai Krishna, Biju Pottakkat · 2025 · World Journal of Clinical Oncology
Genomic divergence between matched primary and metastatic tumors across cancer types: a pan-cancer analysis of 5,692 samples
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Ryan Michael Carr, Martín E. Fernández-Zapico · 2020 · Cancer Discovery
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Kenichiro Furukawa, Keiichi Hatakeyama, Masanori Terashima, Keiichi Fujiya, Yutaka Tanizawa, Etsuro Bando, Takashi Sugino, Kenichi Urakami, Tateaki Naito, Hiroyasu Kagawa et al. · 2022 · Surgical Case Reports
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Emerging Technologies for the Diagnosis and Treatment of Pancreatic Cancer
Magdalena Swierczewska, С. В. Козлов, Pavan P. Adiseshaiah · 2018 · Elsevier eBooks
Novel Molecular Targets and Mechanisms Involved in the Invasion and Metastasis of Pancreatic Cancer
Ziyi Li, Weidong Li, Yuqi Dong, Xueying Sun · 2019 · Clinical Cancer Drugs
The Quest for the Next-Generation of Tumor Targets: Discovery and Prioritization in the Genomics Era
Leonardo Mirandola, Franco M Marincola, Gianluca Rotino, José A. Figueroa, Fabio Grizzi, Robert S. Bresalier, Maurizio Chiriva‐Internati · 2020 · Methods in pharmacology and toxicology
The Hallmarks of Pancreatic Cancer
Alexander Ioannis Damanakis, Florian Gebauer, Felix Popp, Christiane J. Bruns · 2021 · Springer eBooks
RBFOX2 deregulation promotes pancreatic cancer progression and metastasis through alternative splicing
Michelle M. Maurin, Mohammadreza Ranjouri, Katelyn Martin, Robert Miner, Justin Y. Newberg, Dongliang Du, Barbara Ann Centeno, Jason B. Fleming, Xiaoqing Yu, Ernesto Guccione et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
Convergence for Inactivation of TGFβ Signaling Is a Common Feature of Advanced Pancreatic Cancer
Jungeui Hong, Zachary A. Kohutek, Haochen Zhang, Elias-Ramzey R. Karnoub, Rajya L. Kappagantula, Laura DeLong Wood, Christine A. Iacobuzio–Donahue · 2024 · medRxiv
Anti-activin treatment increases T cell infiltration in breast and pancreatic tumours and promotes survival in a SMAD4-null mouse pancreatic cancer model
Simon J. McCluney, Danielle Park, Daniel S.J. Miller, Merima Mehić, Robert Bloxham, Emma de Vries, Xuelu Wang, Stefan Boeing, Luigi D’Antonio, Łukasz Wieteska et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
Probability Distribution for Rare Neutral Mutations in Cancers and Application to Dynamic Precision Medicine of Cancer
Wei He, Matthew D. McCoy, Chen-Hsiang Yeang, Rebecca B. Riggins, Robert A. Beckman · 2025 · bioRxiv
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Opportunities and Resistance to Signal-Targeted Therapies in Pancreatic Cancer: What Can we Learn from Proteomic Studies?
Célia Cintas, Thibaut Douché, Julie Guillermet‐Guibert · 2018 · Preprints.org
Molecular Pathway and Fluorescence In Situ Hybridization Testing of ERBB2 (HER2) Gene Amplification in Invasive Ductal Carcinoma of Breast
Tomasz Jodlowski, K.H. Ramesh · 2019 · Springer eBooks
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Eric D. Young · 2018 · KU ScholarWorks (University of Kansas)
RAS Internal Tandem Duplication Disrupts GAP-binding to Activate Oncogenic Signaling
Andy Nelson, Thomas J. Turbyville, Srisathiyanarayanan Dharmaiah, Megan Rigby, Rendong Yang, John Columbus, Robert M. Stephens, Drew Sciacca, Getiria Onsongo, Anne E. Sarver et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
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Michaël Noë · 2020
Pancreatic Cancer Immuno-oncology in the Era of Precision Medicine
Samarth Hegde · 2020 · Indian Journal of Surgical Oncology
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Ashton Anthony Connor, Robert Edward Denroche, Gun Ho Jang, Mathieu Lemire, Amy Xin Wei Zhang, Michelle Chan‐Seng‐Yue, Gavin W. Wilson, Daniele Merico, Ilinca M. Lungu, John M.S. Bartlett et al. · 2018 · SSRN Electronic Journal
Gemcitabine Resistance Elicits a Calcium Dependent Epigenetic Reprogramming in Pancreatic Cancer
Ana P. Kutschat · 2021
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Yuning J. Tang, Jianguo Huang, Hidetoshi Tsushima, Hongyuan Zhang, Kristianne Michelle Oristian, Nerissa T. Williams, Xiruo Ding, Jianhong Ou, Sin‐Ho Jung, Dadong Zhang et al. · 2018 · SSRN Electronic Journal
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Eytan Ruppin, Sanju Sinha · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
Precision Medicine Based on Next Generation Sequencing and Master Controllers
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Célia Cintas, Thibaut Douché, Julie Guillermet‐Guibert · 2018 · Preprints.org
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Christina M. Ferrer, Ruben Boon, Hyo Min Cho, Tiziano Bernasocchi, Lai Ping Wong, Murat Çetinbaş, Elizabeth R. Haggerty, Irene Rin Mitsiades, Gregory R. Wojtkiewicz, Daniel E. McLoughlin et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
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Additional file 6 of High-resolution Hi-C maps highlight multiscale 3D epigenome reprogramming during pancreatic cancer metastasis
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Additional file 2 of High-resolution Hi-C maps highlight multiscale 3D epigenome reprogramming during pancreatic cancer metastasis
Bo Ren, Jinshou Yang, Chengcheng Wang, Gang Yang, Huanyu Wang, Chen, Yuan, Ruiyuan Xu, Xuning Fan, Lei You, Taiping Zhang et al. · 2021 · Figshare
Additional file 3 of Integrated genomic and transcriptomic analysis reveals unique characteristics of hepatic metastases and pro-metastatic role of complement C1q in pancreatic ductal adenocarcinoma
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Additional file 5 of High-resolution Hi-C maps highlight multiscale 3D epigenome reprogramming during pancreatic cancer metastasis
Bo Ren, Jinshou Yang, Chengcheng Wang, Gang Yang, Huanyu Wang, Chen, Yuan, Ruiyuan Xu, Xuning Fan, Lei You, Taiping Zhang et al. · 2021 · Figshare
Additional file 4 of High-resolution Hi-C maps highlight multiscale 3D epigenome reprogramming during pancreatic cancer metastasis
Bo Ren, Jinshou Yang, Chengcheng Wang, Gang Yang, Huanyu Wang, Chen, Yuan, Ruiyuan Xu, Xuning Fan, Lei You, Taiping Zhang et al. · 2021 · Figshare
Additional file 2 of Integrated genomic and transcriptomic analysis reveals unique characteristics of hepatic metastases and pro-metastatic role of complement C1q in pancreatic ductal adenocarcinoma
Jian‐Yu Yang, Ping Lin, Minwei Yang, Wei Chiang Liu, Xueliang Fu, Dejun Liu, Ling‐Ye Tao, Yan‐Miao Huo, Junfeng Zhang, Rong Hua et al. · 2021 · Figshare
Additional file 3 of High-resolution Hi-C maps highlight multiscale 3D epigenome reprogramming during pancreatic cancer metastasis
Bo Ren, Jinshou Yang, Chengcheng Wang, Gang Yang, Huanyu Wang, Chen, Yuan, Ruiyuan Xu, Xuning Fan, Lei You, Taiping Zhang et al. · 2021 · Figshare
Additional file 1 of High-resolution Hi-C maps highlight multiscale 3D epigenome reprogramming during pancreatic cancer metastasis
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Additional file 7 of High-resolution Hi-C maps highlight multiscale 3D epigenome reprogramming during pancreatic cancer metastasis
Ren, Bo, Yang, Jinshou, Wang, Chengcheng, Yang, Gang, Wang, Huanyu, Chen, Yuan, Xu, Ruiyuan, Fan, Xuning, You, Lei, Zhang, Taiping et al. · 2021 · Figshare
Additional file 1 of Integrated genomic and transcriptomic analysis reveals unique characteristics of hepatic metastases and pro-metastatic role of complement C1q in pancreatic ductal adenocarcinoma
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Additional file 2 of HATCHet2: clone- and haplotype-specific copy number inference from bulk tumor sequencing data
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Additional file 1 of Identification of a robust functional subpathway signature for pancreatic ductal adenocarcinoma by comprehensive and integrated analyses
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Additional file 1 of Optimization of a mouse model of pancreatic cancer to simulate the human phenotypes of metastasis and cachexia
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Additional file 1 of HATCHet2: clone- and haplotype-specific copy number inference from bulk tumor sequencing data
Myers, Matthew A., Brian Arnold, Vineet Bansal, Metin Balaban, Katelyn M. Mullen, Simone Zaccaria, Benjamin J. Raphael · 2024 · Figshare
Additional file 4 of Integrated genomic and transcriptomic analysis reveals unique characteristics of hepatic metastases and pro-metastatic role of complement C1q in pancreatic ductal adenocarcinoma
Yang, Jianyu, Lin, Ping, Yang, Minwei, Liu, Wei, Fu, Xueliang, Dejun Liu, Lingye Tao, Yanmiao Huo, Zhang, Junfeng, Hua, Rong et al. · 2021 · Figshare
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