Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource

Dendrou, Calliope A, Plagnol, Vincent, Fung, Erik, Yang, Jennie H M, Downes, Kate, Cooper, Jason D, Nutland, Sarah, Coleman, Gillian +11 more·2009·Nature Genetics

Cited by (281)

Items 201–281 of 281

  1. Stem cells and a cure for type 1 diabetes?
    John A. Todd · 2009 · Proceedings of the National Academy of Sciences
  2. Impact of IL-2 and IL-2R SNPs on Proliferation and Tumor-killing Activity of Lymphokine-Activated Killer Cells from Healthy Chinese Blood Donors
    Yan Li, Fandong Meng, Xin Tian, Chengguang Sui, Yunpeng Liu, Youhong Jiang · 2014 · Asian Pacific Journal of Cancer Prevention
  3. Uveitis characteristics and multiple sclerosis phenotype of patients with multiple sclerosis-associated uveitis: A systematic review and meta-analysis
    Paola Saboya Galindo, Germán Mejía‐Salgado, Carlos Cifuentes‐González, Camilo Andrés Rodríguez-Rodríguez, Laura Boada-Robayo, Rafael Méndez-Marulanda, Joan Sebastián Varela, Laura Riveros-Sierra, Mariana Gaviria-Carrillo, Alejandra de‐la‐Torre · 2024 · PLoS ONE
  4. Bayesian Effect Size Ranking to Prioritise Genetic Risk Variants in Common Diseases for Follow‐Up Studies
    Daniel J. M. Crouch, Jamie R. J. Inshaw, Catherine C. Robertson, Esther Ng, Jiayuan Zhang, Wei‐Min Chen, Suna Önengüt-Gümüşcü, Antony J. Cutler, Carlo Sidore, Francesco Cucca et al. · 2025 · Genetic Epidemiology
  5. Daclizumab, an IL-2 modulating antibody for treatment of multiple sclerosis
    James P. Sheridan, Randy R. Robinson, JOHN W. ROSE · 2013 · Expert Review of Clinical Pharmacology
  6. Association study of IL2RA and CTLA4 Gene Variants with Type I Diabetes Mellitus in children in the northwest of Iran Association study of IL2RA and CTLA4 gene variants with type-1 diabetes mellitus in children in the northwest of Iran
    Mohammad Reza Ranjouri, Parisa Aob, Sima Mansoori Derakhshan, Mahmoud Shekari Khaniani, Hossein Chiti, Ali Ramazani · 2016 · Bioimpacts
  7. Autoimmune Disorders
    Sergio E. Baranzini · 2012 · Elsevier eBooks
  8. Genetic Predisposition, Humans
    Margaret A. Jordan, Judith Field, Helmut Butzkueven, Alan G. Baxter · 2013 · Elsevier eBooks
  9. Where is the causal variant? On the advantage of the family design over the case–control design in genetic association studies
    Claire Dandine‐Roulland, Hervé Perdry · 2015 · European Journal of Human Genetics
  10. Engineering the Biophysical Properties of Basement Membranes into Biomaterials: Fabrication and Effects on Cell Behavior
    Elizabeth J. Tocce, Sara J. Liliensiek, M.J. Wilson, Bernardo Yáñez-Soto, Paul F. Nealey, Catherine Jones Murphy · 2011 · Comprehensive Biomaterials
  11. From genome-wide association studies to etiology: probing autoimmunity genes by RNAi
    Stephan Kissler · 2011 · Trends in Molecular Medicine
  12. Cellules grumelées: old terminology revisited. Regarding the cytologic diagnosis of chronic lymphocytic leukemia and well-differentiated lymphocytic lymphoma in pleural effusions.
    T A Seidel, Archimedes D. Garbes · 1985 · PubMed
  13. T cell subset-selective IL2RA enhancers shape autoimmune diabetes risk
    Dimitre R. Simeonov, Harikesh S. Wong, Jessica T. Cortez, Arabella Young, Zhongmei Li, Vinh Q. Nguyen, Kyemyung Park, Jennifer M. Umhoefer, Alyssa C. Indart, Jonathan M. Woo et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  14. Diabetes Mellitus
    Leslie J. Raffel, Mark O. Goodarzi · 2013 · Elsevier eBooks
  15. Genetic Predisposition, Humans
    Margaret A. Jordan, Alan G. Baxter · 2019 · Elsevier eBooks
  16. Identification of cell types, tissues and pathways affected by risk loci in psoriasis
    Yan Lin, Pan Zhao, Changbing Shen, Songke Shen, Xiaodong Zheng, Xianbo Zuo, Sen Yang, Xuejun Zhang, Xianyong Yin · 2015 · Molecular Genetics and Genomics
  17. A Genomic Road Map for Complex Human Disease
    Peter K. Gregersen · 2014 · Science
  18. A rare IL2RA haplotype identifies SNP rs61839660 as causal for autoimmunity
    Daniel B. Rainbow, Marcin Pekalski, Antony J. Cutler, Oliver S. Burren, Neil M Walker, John A. Todd, Chris Wallace, Linda S. Wicker · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
  19. 4.22 Engineering the Biophysical Properties of Basement Membranes Into Biomaterials: Fabrication and Effects on Cell Behavior ☆
    Elizabeth J. Tocce, Joshua Z. Gasiorowski, A.J. Youssef, Ricardo Alexandrino Garcia, Sara J. Liliensiek, M.J. Wilson, Bernardo Yáñez-Soto, Catherine Jones Murphy, Paul F. Nealey · 2017 · Elsevier eBooks
  20. The immune cell infiltration-associated molecular subtypes and gene signature predict prognosis for osteosarcoma patients
    Bin Liu, Xiangyang Liu, Guoping Wang, Yixin Chen · 2024 · Scientific Reports
  21. Exploring antigenic variation in autoimmune endocrinopathy
    Maria Mavridou, Simon H. S. Pearce · 2025 · Frontiers in Immunology
  22. Role of Genetic Factors in Pathophysiology of Multiple Sclerosis
    An Goris, Bénédicte Dubois, Kelly Hilven · 2015 · Elsevier eBooks
  23. Regulatory T Cells in Autoimmune Diabetes
    Vitalijs Ovcinnikovs, Lucy S. K. Walker · 2015 · Progress in molecular biology and translational science
  24. A Glycerophospholipid Metabolism-Based Prognostic Model Guides Osteosarcoma Therapy
    Yong Wen, Donglian Wang, Hongshen Wang, Jian Zhao, Yao Li, Jin Zhang, Bolai Chen · 2025 · Translational Oncology
  25. Exploring the causal relationship between inflammatory cytokines and myasthenia gravis: A two-way Mendelian randomization study
    Jingyu Li, Yan-Jun Ling, Wenhui Bao, Wen-Na Zhang, Xin-Miao Han, Xiaochen Zheng, Qi Zhao · 2024 · Cytokine
  26. Genetic Determination and Immunopathogenesis of Type 1 Diabetes Mellitus in Humans
    Daniela Kantárová, M Vrlík, Buc M · 2012 · Acta Medica Martiniana
  27. Influence of IL2RA rs2104286 Polymorphism in the Risk of Biopsy-proven Giant Cell Arteritis
    Luis Rodríguez‐Rodríguez, Santos Castañeda, Tomás R. Vázquez-Rodríguez, Inmaculada C. Morado, BEATRIZ MARÍ-ALFONSO, Carmen Gómez‐Vaquero, José Alberto Miranda-Filloy, Norberto Ortego‐Centeno, Javier Narváez, Ricardo Blanco et al. · 2010 · The Journal of Rheumatology
  28. After the Gwas rush: Nuggets of insight into the pathogenesis of autoimmune disease
    Jayne S. Danska, Philippe Poussier · 2009 · Seminars in Immunology
  29. Non-coding sequence variation reveals fragility within interleukin 2 feedback circuitry and shapes autoimmune disease risk
    Dimitre R. Simeonov, Kyemyung Park, Jessica T. Cortez, Arabella Young, Zhongmei Li, Vinh Q. Nguyen, Jennifer M. Umhoefer, Alyssa C. Indart, Jonathan M. Woo, Mark Stuart Anderson et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  30. Granulocyte-Macrophage Colony-Stimulating Factor in Central Nervous System Autoimmunity
    Bogoljub Ćirić, Javad Rasouli, Abdolmohamad M. Rostami · 2015 · Elsevier eBooks
  31. Robust identification of regulatory variants (eQTLs) using a differential expression framework developed for RNA-sequencing
    Mackenzie A. Marrella, Fernando H. Biase · 2023 · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
  32. Diabetes Mellitus
    Reed Edwin Pyeritz · 2024 · Elsevier eBooks
  33. Characterization and effective expansion of CD4−CD8− TCRαβ+ T cells from individuals living with type 1 diabetes
    J. Ernesto Fajardo-Despaigne, Félix Lombard‐Vadnais, Adam‐Nicolas Pelletier, Aïnhoa Olazabal, Lucie Boutin, Sarah Pasquin, Valérie Janelle, Laurent Legault, Jean‐Sébastien Delisle, Erin E. Hillhouse et al. · 2024 · Molecular Therapy — Methods & Clinical Development
  34. Case Report: IL2RA (CD25) deficiency: first reported cases in Morocco
    Ahamada Elamine, Ibtihal Benhsaien, Abderrahmane Errami, B. Yousra, Zahra Aadam, Mohammed Fahi, Ahmed Aziz Bousfiha, Jalila El Bakkouri, Fatima Ailal · 2026 · Frontiers in Immunology
  35. A systems genetics approach to the characterization of differential low dose radiation responses in BXD recombinant inbred mice
    Rachel Lynch · 2010
  36. The Genetics of Type 1 Diabetes
    Marchal Kathleen · 2011 · InTech eBooks
  37. Cardiovascular Lesions of Kawasaki Disease: From Genetic Study to Clinical Management
    Ho‐Chang Kuo, Wei‐Chiao Chang · 2012 · InTech eBooks
  38. Variants génétiques associés au diabète de type 1 et contrôle de l’expression du récepteur de l’IL-2
    Vincent Plagnol · 2010 · médecine/sciences
  39. The Role of T Lymphocytes in the Pathogenesis of Autoimmune Type 1 Diabetes: Implications for Potential Virus-Mediated Pathways
    Martin Eichmann, Mark Peakman · 2012 · Springer eBooks
  40. Update on Genetic Determinants of Type1 Diabetes
    Philippe Antoine Lysy · 2016 · Journal of Molecular and Genetic Medicine
  41. Pharmacokinetic drug evaluation of daclizumab for the treatment of relapsing-remitting multiple sclerosis
    Francesco Patti, Clara Grazia Chisari, Emanuele D’Amico, Mario Zappia · 2018 · Expert Opinion on Drug Metabolism & Toxicology
  42. Variants génétiques associés au diabète de type 1 et contrôle de l’expression du récepteur de l’IL-2
    Vincent Plagnol · 2010 · Springer Link (Chiba Institute of Technology)
  43. Genetics of Multiple Sclerosis
    Julia Y. Mescheriakova, Karim L. Kreft, Rogier Q. Hintzen · 2013 · Springer eBooks
  44. “Omics” and the immunopathogenesis of multiple sclerosis
    An Goris · 2011 · Neuroscience Letters
  45. CISH promoter polymorphism effects on T cell cytokine receptor signaling and type 1 diabetes susceptibility
    Julia Seyfarth, Heinz Ahlert, Joachim Rosenbauer, Christina Bächle, Michael Roden, Reinhard Walter Holl, Ertan Mayatepek, Thomas Meißner, Marc Jacobsen · 2018 · Molecular and Cellular Pediatrics
  46. Gut Microbiota in Brain Development and Disorders of the CNS: Therapeutic Strategies Involving Dietary Modification, Pro- and Prebiotic Intervention, and Fecal Microbiota Transplantation (FMT) Therapy
    Bryan C. Tungland · 2018 · Elsevier eBooks
  47. Common Genetic Component in Autoimmunity
    Gisela Orozco, Blanca Rueda‐Medina · 2019 · Rare diseases of the immune system
  48. Genetics of Multiple Sclerosis
    Ahmad Abdulaziz Abulaban, David A. Hafler, Erin E. Longbrake · 2019 · Royal Society of Chemistry eBooks
  49. Reduced GLP-1 response to a meal is associated with the CTLA4 rs3087243 G/G genotype
    András Zóka, Gábor Barna, Gábor Nyírő, Ágnes Molnár, László Németh, Györgyi Műzes, Anikó Somogyi, Gábor Firneisz · 2019 · Central European Journal of Immunology
  50. A family matter: Anti-viral antibody responses
    Xaquín Castro Dopico, Gunilla B. Karlsson Hedestam · 2022 · Immunity
  51. Genetics of Rheumatic Diseases
    Stephen Eyre, Peter K. Gregersen, Anne C Barton · 2016 · Elsevier eBooks
  52. Molecular genetics of type 1 diabetes
    M. A. Kelly, Simon D. Rees, Anthony H Barnett, Stephen Charles Bain · 2015
  53. No Causal Association Between C-Reactive Protein and the Risk of Type 1 Diabetes: A Bidirectional Mendelian Randomization Study
    Fengyuan Tian, Shuo Huang, Wangda Xu, Xiaohong Feng, Jie Chen, Xi Wang, Qi Huang · 2022 · Research Square
  54. DACS-DB: An Annotation and Dissemination Model for Disease Associated Cytokine SNPs
    Sushant Bhushan · 2011 · IUScholarWorks (Indiana University)
  55. Nuevas herramientas para el estudio de la esquistosomosis: valoración de nuevos fármacos y estudio de la susceptibilidad a la infección
    Luis Pérez del Villar-Moro · 2012
  56. Genetic architecture of early pre-inflammatory stage transcription signatures of autoimmune diabetes in the pancreatic lymph nodes of the NOD mouse reveals significant gene enrichment on chromosomes 6 and 7
    Béatrice Regnault, Evie Melanitou · 2015 · Meta Gene
  57. The Roles of Iddm30 and Iddm24 in the Immunopathogenesis of Type 1 Diabetes in BioBreeding Rats
    Ying-Chieh Gary Chao · 2015 · TSpace (University of Toronto)
  58. Genetics and epigenetics of rheumatoid
    Darren Plant, Soumya Raychaudhuri · 2013
  59. Genome-environment Interactions in Type 1 Diabetes
    Janet Markle · 2013 · TSpace (University of Toronto)
  60. Determining the role of the IL2 pathway in susceptibility to juvenile idiopathic arthritis
    Christopher J. Taylor · 2018 · Research Explorer (The University of Manchester)
  61. Genetics of Rheumatic Diseases
    Peter K. Gregersen · 2013 · Elsevier eBooks
  62. Polycyclic aromatic hydrocarbons influence naive CD4+ T cell differentiation
    Amanda J. Dunbar · 2019 · KU ScholarWorks (The University of Kansas)
  63. Polymorphisms and haplotypes of IL2RA, IL-10, IFN-γ, IRF5, and CCR2 are associated with Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in children
    Nannan Tang, Junbin Huang, Chun Chen, Xiaojun Wu, Hong Liang Xu, Guohua Chen, Hongman Xue · 2020
  64. MSGD: a manually curated database of genomic, transcriptomic, proteomic and drug information for multiple sclerosis
    Tao Wu, Yaopan Hou, Guanghao Xin, Jingyan Niu, Shanshan Peng, Fanfan Xu, Ying Li, Yuling Chen, Yifangfei Yu, Huixue Zhang et al. · 2024 · Database
  65. Иммунологические аспекты гнездной алопеции: от патогенеза к терапевтическим стратегиям
    M. G. Novosartyan · 2024 · International journal of medicine and psychology.
  66. Additional file 2 of Robust identification of regulatory variants (eQTLs) using a differential expression framework developed for RNA-sequencing
    Mackenzie A. Marrella, Fernando H. Biase · 2024 · Figshare
  67. Additional file 3 of Robust identification of regulatory variants (eQTLs) using a differential expression framework developed for RNA-sequencing
    Mackenzie A. Marrella, Fernando H. Biase · 2024 · Figshare
  68. Additional file 9 of Robust identification of regulatory variants (eQTLs) using a differential expression framework developed for RNA-sequencing
    Mackenzie A. Marrella, Fernando H. Biase · 2024 · Figshare
  69. Additional file 1 of Robust identification of regulatory variants (eQTLs) using a differential expression framework developed for RNA-sequencing
    Mackenzie A. Marrella, Fernando H. Biase · 2024 · Figshare
  70. Additional file 7 of Robust identification of regulatory variants (eQTLs) using a differential expression framework developed for RNA-sequencing
    Mackenzie A. Marrella, Fernando H. Biase · 2024 · Figshare
  71. Additional file 8 of Robust identification of regulatory variants (eQTLs) using a differential expression framework developed for RNA-sequencing
    Mackenzie A. Marrella, Fernando H. Biase · 2024 · Figshare
  72. Additional file 6 of Robust identification of regulatory variants (eQTLs) using a differential expression framework developed for RNA-sequencing
    Mackenzie A. Marrella, Fernando H. Biase · 2024 · Figshare
  73. Additional file 5 of Robust identification of regulatory variants (eQTLs) using a differential expression framework developed for RNA-sequencing
    Mackenzie A. Marrella, Fernando H. Biase · 2024 · Figshare
  74. Additional file 4 of Robust identification of regulatory variants (eQTLs) using a differential expression framework developed for RNA-sequencing
    Mackenzie A. Marrella, Fernando H. Biase · 2024 · Figshare
  75. Les exosomes, médiateurs fondamentaux de la communication intercellulaire au cours de l'infection par les bactéries AIEC impliquées dans la maladie de Crohn
    Anaïs B. Larabi · 2019 · theses.fr (ABES)
  76. Facteurs génétiques et post-génétiques associés au développement de la sclérose en plaques
    Pierre‐Paul Axisa · 2017 · theses.fr (ABES)
  77. Etude statique et dynamique de l’immunome dans les pathologies autoimmunes et inflammatoires chroniques
    Roberta Lorenzon · 2020 · theses.fr (ABES)
  78. Integrative single-cell and spatial transcriptomic approaches to decipher the tumor microenvironment and therapeutic resistance in pancreatic cancer
    Mengting Luo, Feng Shen, Wanli Xu, Christopher Peter Corpe, Jin Wang · 2026 · Cancer Biology & Therapy
  79. Single-cell RNA sequencing uncovers an immunosuppressive program in PDAC mast cells: tumour-driven activation, proliferation, and association with Treg recruitment
    Mengli Wu, Xuxia Ye, Qi Yu, Hui Huang, Zhezhong Zhang, Xiaoli Yu, Songmei Lou, Jian Xu · 2026 · Annals of Medicine
  80. Regulatory T cell function and engineering for next generation cell therapies
    Nathan W. Zammit, Martina Sassone‐Corsi, Payam Zarin, Tingxi Guo, Maegan E. Hoover, Marko Repic, Gene I. Uenishi, Christopher L. Moore, Dalia E. Gaddis, March A. Bach et al. · 2026 · Frontiers in Immunology
  81. A study of the variation of leukocyte immunoglobulin-like receptors on antigen-presenting cells
    Patrick Yong · 2013 · UPT. Syiah Kuala University Library (Syiah Kuala University)