Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3

Chen, Zi-Jiang, Zhao, Han, He, Lin, Shi, Yuhua, Qin, Yingying, Shi, Yongyong, Li, Zhiqiang, You, Li +26 more·2011·Nature Genetics

Cited by (785)

Items 601–700 of 785

  1. GLP-1R, a novel receptor in platelets, and the use of liraglutide in the treatment of obesity in women with PCOS
    Hassan Kahal · 2013 · Repository@Hull (Worktribe) (University of Hull)
  2. Leukocyte Telomere Length and Polycystic Ovary Syndrome: A Transethnic Mendelian Randomization Study
    Lan Cao, Jie Chen · 2024 · Journal of Bio-X Research
  3. Association between insulin‐associated gene polymorphisms and new‐onset diabetes mellitus in statin‐treated patients
    Minju Park, Jung Sun Kim, Yoon‐A Park, Da Hoon Lee, Seo‐A Choi, Yoonkyung Chang, Tae‐Jin Song, Hye Sun Gwak, Jeong Yee · 2024 · European Journal of Clinical Investigation
  4. AI-Driven Polygenic Risk Scores and Genetic Insights for Polycystic Ovary Syndrome (PCOS) Susceptibility and Diagnosis
    Susmit Kosta, Megha Chandra Singh · 2025 · Obstetrics and gynecology.
  5. Familial Aggregation and Contribution of Various Genes in PCOS
    Sandeep Kumar Mathur, Naincy Purwar · 2025 · BENTHAM SCIENCE PUBLISHERS eBooks
  6. Integrative Nutrigenomics Approach in Polycystic Ovarian Syndrome: Targeting Gene-Diet Interactions for Personalized Nutraceutical Interventions
    Shalini Singh, Maneesha Rana, Satyendra Kumar Rajput, Rajesh Kumar Mishra, Shalini Mishra, Vedpriya Arya · 2026 · Journal of Nutrition
  7. Polycystic Ovary Syndrome in Young Women: Issues and Consequences
    Robert John Norman, Lisa Moran · 2014 · Nestlé Nutrition Institute Workshop series
  8. Could insulin receptor H1085H C > T single nucleotide polymorphism predict insulin resistance in type 2 diabetic and chronic hepatitis C virus patients in Egypt?
    Rania Nabil Bedair, Gehan Mahmoud Magour, Said Ahmed Ooda, Eman M. Amar, Ahmad Awad · 2021 · Egyptian Liver Journal
  9. Study on the Relationship between 5-HttLPR Gene and BDNF Gene Polymorphism and Post-Traumatic Stress Disorder in Li and Han Nationality of Hainan Province
    Haiyan Lin, Juncheng Guo, Guo Min, Xiangling Jiang · 2022 · Health
  10. Insulin Resistance and Lipotoxicity in PCOS: Causes and Consequences
    Anne‐Marie Carreau, Marie‐Claude Battista, Jean‐Patrice Baillargeon · 2022 · Springer eBooks
  11. Recent Advances in the Genetics of Polycystic Ovary Syndrome
    Michelle R. Jones, Mark O. Goodarzi · 2022 · Springer eBooks
  12. Precision Medicine in Endocrinology Practice
    Hamid Reza Aghaei Meybodi, Mandana Hasanzad, Negar Sarhangi, Bagher A. Larijani · 2022 · Springer eBooks
  13. In vitro activation of ovarian follicles
    Kazuhiro Kawamura · 2023 · Elsevier eBooks
  14. Genetics and Epigenetics of Polycystic Ovary Syndrome
    Surya Prakash Goud Ponnam, Adity Paul · 2023 · Obstetrics and gynecology.
  15. Polycystic ovary syndrome and the rs10818854 and rs10986105 variants of the DENND1A gene: An association study among Bangladeshi women
    Zinia Haidar, Hurjahan Banu, Md Shahed Morshed, Sharif Akhteruzzaman, Muhammad Abul Hasanat, Abu Ashfaqur Sajib · 2024 · Gene Reports
  16. Disorders of carbohydrate metabolism and candidate genes for the pathophysiology of polycystic ovary syndrome. A literature review
    Абашова Елена Ивановна, Maria Igorevna Yarmolinskaya, Natalia S. Osinovskaya · 2023 · Journal of obstetrics and women s diseases
  17. PCOS – Kinderwunsch und Schwangerschaft
    Katharina Hancke · 2024 · Geburtshilfe und Frauenheilkunde
  18. Molecular study of CYP21 gene polymorphism rs13405728 and CYP11A1 gene polymorphism rs4077582 in polycystic ovarian syndrome patients
    Nawal Sajid, Aqsa Kiran, Anisa Iftikhar, Kashif Bashir · 2024 · The Journal of Basic and Applied Zoology
  19. Polycystic Ovarian Syndrome: Current Insights
    S. J. K. Naidu, Sapna Ramdin, Thajasvarie Naicker, Jagidesa Moodley, Girija Naidoo, Nalini Govender · 2024 · Biomedical visualization
  20. Genetic factors responsible for ovarian hyperandrogenism in women
    Л. М. Семенюк, М. Є. Яроцький · 2016 · Clinical endocrinology and endocrine surgery
  21. Polycystic Ovary Syndrome in adolescents: an update
    L. Caserta, A. Gregnuoli · 2020 · Italian Journal of Gynaecology and Obstetrics
  22. Polycystic ovary syndrome
    Roger A. Lobo · 2021 · Elsevier eBooks
  23. Initiation of oogenesis and meiosis in the fetal ovary depends on Dennd1a-mediated production of Wnt5a and retinoic acid from the somatic niches
    Jingjing Shi, Qun Niu, Qing Gao, Jiang Fu, Jinlong Ma · 2021 · Frontiers in Bioscience-Landmark
  24. Relationship of follicle stimulating hormone receptor Gene Thr307Ala polymorphism with polycystic ovary syndrome in Iraqi women
    2019 · American Journal of BioMedicine
  25. Landing Eyes on Unnoticed Disorder: A Polycystic Ovary Syndrome
    Jay Davariya · 2022 · International Journal of Current Science Research and Review
  26. Association between Non Alcoholic Fatty Liver Disease and Polycystic Ovarian Syndrome: A Systematic Review
    Ashraf MU · 2022 · Gastroenterology & Hepatology International Journal
  27. Sonographic Correlation of Polycystic Ovaries (PCO) with the Fatty Liver
    C. A. H. M. Enamullah, Tamanna Jahan, Tahmina Begum, Abid Sikdar, Arzu Manth Ara Begum, Wanaiza Rahman · 2023 · Scholars International Journal of Obstetrics and Gynecology
  28. Gonadotropin Receptor Cross-Talk and Altered Functions in Gonadal and Non-Gonadal Tissues
    Rita Singh, Anjali Pathak · 2023 · Journal of Endocrinology & Reproduction
  29. Polycystic Ovary Syndrome, Obesity and Insulin Resistance
    Samantha Cassar · 2014 · Victoria University Research Repository (Victoria University)
  30. Commentary: The New International Guideline for diagnosis and management of PCOS was worth the effort
    Stephen Franks · 2018 · Clinical Endocrinology
  31. Joseph W. Goldzieher on the occasion of his 100th birtday
    Giuseppe Benagiano, Ivo A Brosens · 2019 · The European Journal of Contraception & Reproductive Health Care
  32. Avaliação do perfil de miRNAs circulantes em pacientes com síndrome dos ovários policísticos
    Giovana De Nardo Maffazioli · 2021
  33. Transcriptome-wide association study identified candidate genes associated with polycystic ovary syndrome
    Yingzhou Shi, Changrong Li, Hongjie Yu, Xinyu Chen, Ping Shi, Chao Xu · 2023 · medRxiv
  34. SRI 2023: Scientific Program & Abstracts
    Sharon Lisa Perrella, J. McEachran, Alethea Rea, S.A. Prosser, Mary E. Wlodek, Donna Tracy Geddes · 2023 · Reproductive Sciences
  35. Association of LHCGR gene variant rs2293275 with the polycystic ovary syndrome risk: an updated meta-analysis
    Mohanand A. Ibrahim, Mikhlid Hammad Almutairi, Bader O. Almutairi · 2023 · Research Square
  36. 54 The Female Patient: Pregnancy and Gynecologic Issues in the Bariatric Surgery Patient
    Karina A. McArthur, Giselle G. Hamad, George Michel Eid · 2014 · Springer eBooks
  37. Efeitos da exposição neonatal a esteróides sexuais no hipotálamo e ovário de ratas adultas: modelos animais da síndrome dos ovários policísticos
    Rodrigo Rodrigues Marcondes · 2012
  38. Medical genetics: Markers for polycystic ovary syndrome
    Felix Cheung · 2011 · Nature China
  39. Risk reduction strategies for assisted conception in women with polycystic ovary syndrome
    Susan Louise Nicholas · 2015 · White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)
  40. Enrichment of genetic variants related to infertility in females seeking fertility treatment
    Sasha E. Parets, Andrew Pollock, R. Shraga, Matthew Akana, Michael Jansen, Alexander Bisignano, Óscar Puig · 2017 · Fertility and Sterility
  41. Fertility and reproductive health: the challenges and strategies in reproductive medicine—A summary of the 170th “Shuangqing Forum”
    Jing Cheng, Qi Zhou, Yan-Ling WANG, Chan TIAN, Xue Zhang, Jiahao Sha, Qunyan Lyu, Hong Zhang, Jie QIAO, Erdan Dong · 2017 · Scientia Sinica Vitae
  42. Effects of dietary polyphenols on vascular endothelium and cardiovascular health
    E. Ehtesham · 2017 · Repository@Hull (Worktribe) (University of Hull)
  43. Polycystic Ovary Syndrome. Androgen excess and insulin resistance in women: Identification of molecular targets to improve glucose homeostasis
    Milana Kokosar · 2018 · Gothenburg University Publications Electronic Archive (Gothenburg University)
  44. Genome-Wide Association Studies of Ovarian Function Disorders
    Chi‐Kwan Leung, Han Zhao, Yue Lv, Gang Lu, Zi‐Jiang Chen · 2018 · Elsevier eBooks
  45. Novel interventional therapies to improve cardiovascular risk in women with polycystic ovary syndrome
    Zeeshan Javed · 2018 · Repository@Hull (Worktribe) (University of Hull)
  46. 大发现时代的“生命组学”(代序)
    福初 贺 · 2013 · Scientia Sinica Vitae
  47. Tuning Hyperparameters in Supervised Learning Models and Applications of Statistical Learning in Genome-Wide Association Studies with Emphasis on Heritability
    Jill F. Lundell · 2020 · Digital Commons - USU (Utah State University)
  48. Correlation Analysis of 5-HTTLPR Polymorphism and Post-Traumatic Stress Disorder in Li and Han Nationalities of Hainan Province
    Ning Bei, Min Guo, Ping Hsin Huang, Juncheng Guo, Xiangling Jiang, Hong Yue Gao, Long Dengyi · 2019 · World Journal of Neuroscience
  49. Colocalization highlights genes in hypothalamic–pituitary–gonadal axis as potentially mediating polycystic ovary syndrome risk
    Jenny C. Censin, Jonas Bovijn, Michael Vaclav Holmes, Cecilia M. Lindgren · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  50. The Relationship Between The AMHR2 SNP (–482 A andgt;G) With The Level of The Hormone, Oxidative Stress Status and IL-18 in PCOS Iraqi Woman
    Roaa Mohammed Jabbar, Batool Ali Ahmed, Enaas Saleh Jawad · 2019 · International Journal of Pharmaceutical Quality Assurance
  51. Genetics of polycystic ovarian syndrome
    Yvonne V. Louwers, Joop S.E. Laven · 2020 · Elsevier eBooks
  52. Identification of genetic causes of gynecologic disorders
    Alexander M. Kotlyar, Maria D. Lalioti · 2020 · Elsevier eBooks
  53. Etiopatogenia da síndrome dos ovários policísticos: abordagem multifatorial da infância à idade reprodutiva
    Lívia Reis Silva · 2020
  54. A kaleidoscopic view of ovarian genes associated with polycystic ovary syndrome
    Sezcan Mümüşoğlu, Qingling Yang, Aaron J.W. Hsueh · 2021 · F&S Reviews
  55. PCOS, Hashimoto's disease, celiac disease, endometriosis - genetically conditioned autoimmune disorder causing infertility?
    Katarzyna K. Jankowska, Aleksandra Kaźmierczak-Dejewska · 2021 · Kwartalnik Naukowy Fides et Ratio
  56. Utilização do sequenciamento em larga escala como ferramenta para identificação de causas monogênicas da síndrome de ovários policísticos
    Raiane Pina Crêspo Teixeira · 2021
  57. Epistasis Detection via the Joint Cumulant
    Randall Reese, Guifang Fu, Geran Zhao, Xiaotian Dai, Xiaotian Li, Kenneth Chiu · 2022 · Statistics in Biosciences
  58. Hypogonadotropic and Hypergonadotropic Hypogonadism in Females: Disorders of Reproductive Ducts
    Joe Leigh Simpson · 2021 · Elsevier eBooks
  59. Genetics and Gynaecological Disease
    Isabella Borg, Nikolai Paul Pace · 2021 · Cambridge University Press eBooks
  60. Profile of Dr. Zi-Jiang Chen
    2020 · Science China Life Sciences
  61. Polycystic Ovary Syndrome
    Sezcan Mümüşoğlu, Bülent Okan Yıldız · 2022
  62. Nonneoplastic Lesions of the Ovary
    Julie A. Irving, Philip B. Clement · 2018 · Springer eBooks
  63. Thyroid Dysfunction: In Connection with PCOS
    Mariya Anwaar, Qaiser Jabeen · 2022 · IntechOpen eBooks
  64. Faculty Opinions recommendation of Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria.
    Fernando Marcos dos Reis · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  65. Loci on chromosome 12q13.2 encompassing ERBB3, PA2G4 and RAB5B are associated with polycystic ovary syndrome
    Ronald Alan Harris, Kellie J. Archer, Mark O. Goodarzi, Timothy P. York, Jeffrey Rogers, Andrea Elizabeth Dunaif, Jan M. McAllister, Jerome F. Strauss · 2022 · medRxiv
  66. The Polymorphism rs7579411 of the LHCGR Gene Is Associated with the Development of Endometrial Hyperplasia
    Irina Ponomarenko, Irina V. Batlutskaya, Valentina S. Orlova, Olga Alekseevna Efremova, Mikhail Ivanovich Churnosov · 2022 · Russian Journal of Genetics
  67. Genetic markers of polycystic ovary syndrome: role in the pathogenesis and phenotypic manifestations of the disease
    Anna Borisovna Khuraseva, Святченко Ксения Сергеевна · 2022 · Medical alphabet
  68. PCOS – Kinderwunsch und Schwangerschaft
    Katharina Hancke · 2023 · DMW - Deutsche Medizinische Wochenschrift
  69. Prospective Role of Leptin Receptor Gene and its Polymorphisms on the Onset of Polycystic Ovarian Syndrome
    Keerthi Vanamala, Srujana Medithi · 2023 · Current Women s Health Reviews
  70. Genomics in reproductive medicine: Current and future applications
    Maurizio Poli, Antonio Capalbo · 2023 · Elsevier eBooks
  71. Genetics of polycystic ovary syndrome
    Tristan Hardy, Alice P. Rogers, Robert John Norman · 2023 · Elsevier eBooks
  72. Developmental origins and genetic basis of polycystic ovary syndrome
    TM Barber, Stephen Franks · 2023 · Elsevier eBooks
  73. COMPUTATIONAL BIOLOGY APPROACHES AND BIOINFORMATICS TO IDENTIFY KEY GENES IN POLYCYSTIC OVARY SYNDROME: A SYSTEMATIC REVIEW
    Seyede Nafise Tabatabaei, Zarrin Minuchehr · 2023 · Studies in Medical Sciences
  74. Chromosomal polymorphisms and susceptibility to menstrual disorders: a retrospective analysis of 24,578 women
    Cheng Ran, Luo Xiaoyan, Zhou Wenjie, Zhou Xiaoyang, Nie Ying, Xiaoyong Qiao, Yang Zhilan, Xu Liangzhi · 2023 · Archives of Gynecology and Obstetrics
  75. An Intricate relationship between Microbes and Metabolites leads of Novel PCOS Biomarkers
    Vidya Niranjan, Sunil Eshwar, S Pooja, Akshay Uttarkar, S Likitha · 2023 · Research Square
  76. SOPK, une pathologie fréquente, et mal nommée
    Philippe Bouchard · 2023 · Elsevier eBooks
  77. ВАРИАНТ RS7579411 ГЕНА LHCGR АССОЦИИРОВАН С РАЗВИТИЕМ ГИПЕРПЛАЗИИ ЭНДОМЕТРИЯ
    Пономаренко, И. В., Батлуцкая, И. В., Орлова, B. C., Ефремова, O. А., Чурносов, М. И. · 2022 · Генетика
  78. Genetic Testing in Polycystic Ovary Syndrome
    Ankur Saharan, Vertika Singh, Singh Rajender · 2023 · Springer eBooks
  79. Additional file 41 of Evidence for causal effects of polycystic ovary syndrome on oxidative stress: a two-sample mendelian randomisation study
    Yifu Pu · 2023 · Figshare
  80. Polytechnic Overeat Sintrems and Disease
    Sahilsingh Ravindrasingh Pardeshi Bhushan · 2023 · International Journal of Science and Research (IJSR)
  81. Novel pleiotropic variants associated with type 2 diabetes and polycystic ovary syndrome detected using a pleiotropic cFDR method
    Yuanyuan Hu, Xinghuan Wang, Rui-Ke Liu, Zhi-Mei Feng, Zhi Chen, Libo Chen, Jie Shen · 2024 · International Journal of Diabetes in Developing Countries
  82. The Impact of Hyperandrogenism in Female Obesity and Cardiometabolic Disease Associated with Polycystic Ovary Syndrome
    Thomas M. Barber, Petra Hanson, Stephen Franks · 2024 · Springer eBooks
  83. Follicle-stimulating hormone (FSH)
    Daniele Santi, Livio Casarini, Gary R. Marshall, Manuela Simoni · 2024 · Elsevier eBooks
  84. Causal Effects of Immune Cells on Reproductive Ill-Health, Including Abnormal Spermatozoa, Polycystic Ovary Syndrome and Spontaneous Abortion: Mendelian Randomization Analyses
    Shuang Chen, Shihao Sun, Zihan Zhou, Zhaokai Zhou, Ran Zhang, Wenyan Song, Hang Xin, Qingling Yang, Shanjun Dai, Kai Huang et al. · 2025 · Journal of Multidisciplinary Healthcare
  85. Genetic landscape of primary ovarian insufficiency in Bangladeshi women through whole exome sequencing
    Hasna Hena Pervin, Rabeya Akter Mim, Athoi Ganguly, Rezaul Karim Kazal, Rohit Gutgutia, Tamannyat Binte Eshaque, Farjana Binta Omar, Atikur Rahaman, Md Nahid Hasan, Amirul Islam et al. · 2025 · Clinica Chimica Acta
  86. Genetics of infertility and “assisted fertilization” in the Bible: The case of Abraham and his family
    Manuela Simoni, Frank Tüttelmann, Livio Casarini · 2025 · Andrology
  87. CLINICAL PROFILE AND OUTCOMES OF PATIENTS WITH POLYCYSTIC OVARIAN SYNDROME
    Mili Poonia · 2025 · Journal of Population Therapeutics and Clinical Pharmacology
  88. In-silico analysis of non-synonymous SNPs in insulin binding site of insulin receptor and screening in Indian PCOS women
    Prayukta Padelkar, Kuppachi Himaja, Anuradha V, Deekshitha Dinakar, Viswas Kathireshakumar, S Sharini, Monisha Mohan, Balasundaram Usha · 2025 · Gene Reports
  89. Multimodal Integration of Genomic Data Reveals Regulatory Mechanisms at the Polycystic Ovary Syndrome (PCOS)-Associated 12q13.2 Locus
    Ronald Alan Harris, Jan M. McAllister, Jerome F. Strauss · 2025 · International Journal of Molecular Sciences
  90. Miscellaneous Comorbidities in PCOS
    Gumpeny Ramachandra Sridhar, G. Muni Nagamani · 2025 · BENTHAM SCIENCE PUBLISHERS eBooks
  91. Recent Advances in the Genetics of Polycystic Ovary Syndrome
    Michelle R. Jones, Ning Xu, Mark O. Goodarzi · 2013 · Springer eBooks
  92. Additional file 11 of Evidence for causal effects of polycystic ovary syndrome on oxidative stress: a two-sample mendelian randomisation study
    Yifu, Pu · 2023 · Figshare
  93. Additional file 20 of Evidence for causal effects of polycystic ovary syndrome on oxidative stress: a two-sample mendelian randomisation study
    Yifu, Pu · 2023 · Figshare
  94. Additional file 17 of Evidence for causal effects of polycystic ovary syndrome on oxidative stress: a two-sample mendelian randomisation study
    Yifu, Pu · 2023 · Figshare
  95. Additional file 9 of Evidence for causal effects of polycystic ovary syndrome on oxidative stress: a two-sample mendelian randomisation study
    Yifu, Pu · 2023 · Figshare
  96. Additional file 42 of Evidence for causal effects of polycystic ovary syndrome on oxidative stress: a two-sample mendelian randomisation study
    Yifu, Pu · 2023 · Figshare
  97. Additional file 33 of Evidence for causal effects of polycystic ovary syndrome on oxidative stress: a two-sample mendelian randomisation study
    Yifu, Pu · 2023 · Figshare
  98. Additional file 38 of Evidence for causal effects of polycystic ovary syndrome on oxidative stress: a two-sample mendelian randomisation study
    Yifu, Pu · 2023 · Figshare
  99. Additional file 2 of Progress of the application clinical prediction model in polycystic ovary syndrome
    Guixue Guan, Yifu, Pu, Yuan, Gao, Xialei, Liu, Fan, Shi, Qian, Sun, Jinjin Xu, Linna, Zhang, Xiaozuo, Zhang, Feng Wen et al. · 2024 · Figshare
  100. Additional file 3 of Body mass index stratified meta-analysis of genome-wide association studies of polycystic ovary syndrome in women of European ancestry
    Kharis A. Burns, Benjamin H. Mullin, Loes M E Moolhuijsen, Triin Laisk, Jaakko S. Tyrmi, Cui, Jinrui, Ky’Era V. Actkins, Yvonne V. Louwers, Lea Karatheodoris Davis, Frank Dudbridge et al. · 2024 · Figshare