The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Identification of a functional transposon insertion in the maize domestication gene tb1
Open accessAbstract
Genetic diversity created by transposable elements is an important source of functional variation upon which selection acts during evolution. Transposable elements are associated with adaptation to temperate climates in Drosophila, a SINE element is associated with the domestication of small dog breeds from the gray wolf and there is evidence that transposable elements were targets of selection during human evolution. Although the list of examples of transposable elements associated with host gene function continues to grow, proof that transposable elements are causative and not just correlated with functional variation is limited. Here we show that a transposable element (Hopscotch) inserted in a regulatory region of the maize domestication gene, teosinte branched1 (tb1), acts as an enhancer of gene expression and partially explains the increased apical dominance in maize compared to its progenitor, teosinte. Molecular dating indicates that the Hopscotch insertion predates maize domestication by at least 10,000 years, indicating that selection acted on standing variation rather than new mutation.
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Cited by
Regulatory activities of transposable elements: from conflicts to benefits
Chuong, E. B., Elde, N. C., & Feschotte, C. (2017) · Nature Reviews Genetics · doi:10.1038/nrg.2016.139 · Cited by 1,489
Genetic Regulation of Shoot Architecture
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A transposable element in a NAC gene is associated with drought tolerance in maize seedlings
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Metadata
- Authors
- Studer, A., Zhao, Q., Ross-Ibarra, J., & Doebley, J.
- Venue
- Nature Genetics
- Published
- 2011-09-25
- Volume
- 43
- Issue
- 11
- Pages
- 1160-1163
- ISSN
- 1061-4036 (ISSN-L)
- 1546-1718
- OpenAlex
- W2060141463
- Cited by
- 802
- References
- 31
- FWCI
- 36.33
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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