Fine-tuning PU.1
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In preleukemic states (e.g., MDS), PU.1 downregulation permits clonal expansion.
“In preleukemic states (e.g., MDS), where PU.1 downregulation permits clonal expansion 33-35”
From USP7 sustains hematopoietic stem cell homeostasis partially via PU.1 stabilization (2026) · cites this paper as [34]
The citation lists haven’t been fetched yet
References 15 · Cited by 10
- Authors
- Stirewalt, D. L.
- Affiliations
- Fred Hutch Cancer Center (US)
- Corresponding author
- Stirewalt, Derek L
- ORCID
- Stirewalt, Derek L
- Venue
- Nature Genetics
- Published
- 2004-06
- Volume
- 36
- Issue
- 6
- Pages
- 550-551
- ISSN
- 1061-4036 (ISSN-L)
- 1546-1718
- OpenAlex
- W2078026674
- Cited by
- 10
- References
- 15
- Citations by year
- 2025: 1 · 2022: 1 · 2019: 1
- FWCI
- 0.63
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Genetics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Hematology › Acute Myeloid Leukemia Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Chromatin Dynamics
- Health Sciences › Medicine › Hematology › Hematopoietic Stem Cell Transplantation
- Keywords
- PU.1, transcription factors, hematopoiesis, acute myeloid leukemia, gene dosage, transcriptional regulation
- MeSH terms
- Proto-Oncogene Protein Spi-1, Animals, Hematopoiesis, Humans, Mice, Mutant Strains, Models, Genetic, Proto-Oncogene Proteins, Leukemia, Myeloid, Acute, Trans-Activators, Gene Expression, Gene Dosage, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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