The mismatch repair system is required for S-phase checkpoint activation

Brown, Kevin D., Rathi, Abhilasha, Kamath, Ravindra, Beardsley, Dillon I., Zhan, Qimin, Mannino, Jennifer L., Baskaran, R·2003·Nature Genetics

Cited by (206)

Items 101–200 of 206

  1. Evidence that dysregulated DNA mismatch repair characterizes human nonmelanoma skin cancer
    Leah C. Young, Jennifer Listgarten, Martin J. Trotter, Susan E. Andrew, Victor A. Tron · 2007 · British Journal of Dermatology
  2. Evidence for the receipt of DNA damage stimuli by PML nuclear domains
    Archana Varadaraj, Claire L Dovey, Leila N. Laredj, Brian J. Ferguson, CE Alexander, N Lubben, AH Wyllie, T. Rich · 2007 · The Journal of Pathology
  3. DNA mismatch repair proteins promote apoptosis and suppress tumorigenesis in response to UVB irradiation: an in vivo study
    Leah C. Young · 2004 · Carcinogenesis
  4. Deficiencies in Chfr and Mlh1 synergistically enhance tumor susceptibility in mice
    Zheng Fu, Kevin M. Regan, Lizhi Zhang, Michael H. Muders, Stephen N. Thibodeau, Amy J. French, Yanhong Wu, Scott H. Kaufmann, Wilma L. Lingle, Junjie Chen et al. · 2009 · Journal of Clinical Investigation
  5. Assessing the link between BACH1/FANCJ and MLH1 in DNA crosslink repair
    Cantor, Sharon B., Xie, Jenny · 2010 · Environmental and Molecular Mutagenesis
  6. Topoisomerase Inhibitor Coralyne Photosensitizes DNA, Leading to Elicitation of Chk2-Dependent S-phase Checkpoint and p53-Independent Apoptosis in Cancer Cells
    Birija Sankar Patro, Biswanath Maity, Subrata Chattopadhyay · 2009 · Antioxidants and Redox Signaling
  7. A Role for DNA Mismatch Repair Protein Msh2 in Error-Prone Double-Strand-Break Repair in Mammalian Chromosomes
    Jason A Smith, Barbara Criscuolo Waldman, Alan S. Waldman · 2005 · Genetics
  8. The DNA-Mismatch Repair Enzyme hMSH2 Modulates UV-B-Induced Cell Cycle Arrest and Apoptosis in Melanoma Cells
    Markus Seifert, Stefan J. Scherer, Wilfried Edelmann, Markus Böhm, Viktor Meineke, Markus Löbrich, Wolfgang Tilgen, Jörg Reichrath · 2007 · Journal of Investigative Dermatology
  9. MSH3 rs26279 polymorphism increases cancer risk: a meta-analysis.
    Huikai Miao, Liping Chen, Dong-Ping Cai, Wei-ju Kong, Li Xiao, Jie Ming Lin · 2015 · PubMed Central
  10. A Novel Chemotherapeutic Agent to Treat Tumors with DNA Mismatch Repair Deficiencies
    Yongliang Zhang, Jennifer T. Fox, Young-Un Park, Gene Elliott, Ganesha Rai, Mengli Cai, Srilatha Sakamuru, Ruili Huang, Menghang Xia, Kyeryoung Lee et al. · 2016 · Cancer Research
  11. Mismatch repair protein Msh2 contributes to UVB-induced cell cycle arrest in epidermal and cultured mouse keratinocytes
    Marijke van Oosten, Gerdine J. Stout, Claude Backendorf, Heggert G Rebel, Niels de Wind, F. Darroudi, Henk J. van Kranen, Frank R. de Gruijl, Leon H.F. Mullenders · 2004 · DNA repair
  12. The monofunctional alkylating agent N-methyl-N′-nitro-N-nitrosoguanidine triggers apoptosis through p53-dependent and -independent pathways
    Wan-Ju Kim, Dillon I. Beardsley, Aaron W. Adamson, Kevin D. Brown · 2004 · Toxicology and Applied Pharmacology
  13. Differential involvement of the hMRE11/hRAD50/NBS1 complex, BRCA1 and MLH1 in NF-κB activation by camptothecin and X-ray
    Yvette Habraken, Olivier Jolois, Jacques G. Piette · 2003 · Oncogene
  14. Impaired genomic stability and increased oxidative stress exacerbate different features of Ataxia-telangiectasia
    Shelly Ziv, Ori Jacob Brenner, Ninette Amariglio, Nechama I. Smorodinsky, Ronit Galron, Danaise V. Carrion, Weijia Zhang, Girdhar G. Sharma, RAJ KUMAR PANDITA, Manjula Agarwal et al. · 2005 · Human Molecular Genetics
  15. The Complex Roles of DNA Repair Pathways, Inhibitors, Hyperthermia, and Contact Inhibition in Cell Cycle Halts
    Young Sup Lee, Muhammad Bilal Ahmed, Abdullah A. A. Alghamdi, Salman Ul Islam, Haseeb Ahsan · 2022 · Mini-Reviews in Medicinal Chemistry
  16. Nuclear reorganization of DNA mismatch repair proteins in response to DNA damage
    Adam S. Mastrocola, Christopher D. Heinen · 2009 · DNA repair
  17. Interaction between human mismatch repair recognition proteins and checkpoint sensor Rad9-Rad1-Hus1
    Haibo Bai, Amrita Madabushi, Xin Guan, A-Lien Lu · 2010 · DNA repair
  18. Decoupling of DNA damage response signaling from DNA damages underlies temozolomide resistance in glioblastoma cells
    Bo Cui, Stewart P. Johnson, N. Bullock, Francis Ali‐Osman, Darell D. Bigner, Henry S. Friedman · 2010 · Journal of Biomedical Research
  19. Differential Cellular Responses to Prolonged LDR-IR in MLH1-Proficient and MLH1-Deficient Colorectal Cancer HCT116 Cells
    Tao Yan, Yuji Seo, Timothy James Kinsella · 2009 · Clinical Cancer Research
  20. Targeting Mismatch Repair defects: A novel strategy for personalized cancer treatment
    Rumena Begum, Sarah A. Martin · 2015 · DNA repair
  21. High frequency induction of mitotic recombination by ionizing radiation in Mlh1 null mouse cells
    Qi Wang, Olga N. Ponomareva, Michael R. Lasarev, Mitchell S. Turker · 2005 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
  22. In vitro and in vivo modulations of benzo[c]phenanthrene-DNA adducts by DNA mismatch repair system
    Jianxin Wu · 2003 · Nucleic Acids Research
  23. Pharmacological inhibition of ataxia-telangiectasia mutated exacerbates acute kidney injury by activating p53 signaling in mice
    Masahiro Uehara, Tetsuro Kusaba, Tomoharu Ida, Kunihiro Nakai, Tomohiro Nakata, Aya Tomita, Noriko Uehara-Watanabe, Kisho Ikeda, Takashi Kitani, NORIYUKI YAMASHITA et al. · 2020 · Scientific Reports
  24. DNA Damage Checkpoint, Damage Repair, and Genome Stability
    Weifeng Liu, Shanshan Yu, Guanjun Chen, Yue‐zhong Li · 2006 · Acta Genetica Sinica
  25. The ATR-Chk1 pathway plays a role in the generation of centrosome aberrations induced by Rad51C dysfunction
    M. Katsura, Takanori Tsuruga, Osamu Date, T. Yoshihara, Mari Ishida, Y. Tomoda, Masazumi Okajima, Motoki Takaku, Hitoshi Kurumizaka, Aiko Kinomura et al. · 2009 · Nucleic Acids Research
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  27. Deoxyinosine triphosphate induces MLH1/PMS2- and p53-dependent cell growth arrest and DNA instability in mammalian cells
    Yasuto Yoneshima, Nona Abolhassani, Teruaki Iyama, Kunihiko Sakumi, Naoko Shiomi, Masahiko Mori, Tadahiro Shiomi, Tetsuo Noda, Daisuke Tsuchimoto, Yusaku Nakabeppu · 2016 · Scientific Reports
  28. Novel PMS1 Alleles Preferentially Affect the Repair of Primer Strand Loops during DNA Replication
    Naz Erdeniz, Sandra Dudley, Regan Gealy, Sue Jinks-Robertson, R. Michael Liskay · 2005 · Molecular and Cellular Biology
  29. Multiple roles for MSH2 in the repair of a deletion mutation directed by modified single-stranded oligonucleotides
    Katie Maguire, Eric Brian Kmiec · 2006 · Gene
  30. Is mismatch repair really required for ionizing radiation–induced DNA damage signaling?
    Petr Ćejka, Lovorka Stojic, Giancarlo Marra, Josef Jiricny · 2004 · Nature Genetics
  31. Impact of DNA mismatch repair system alterations on human fertility and related treatments
    Minhao Hu, Shuyuan Liu, Ning Wang, Yan Ting Wu, Fan Jin · 2016 · Journal of Zhejiang University SCIENCE B
  32. Hypersensitivity in DNA mismatch repair-deficient colon carcinoma cells to DNA polymerase reaction inhibitors
    T Takahashi, Zhenghua Min, Iichiro Uchida, Michitsune Arita, Yoh Watanabe, Minoru Koi, Hiromichi Hemmi · 2004 · Cancer Letters
  33. Interplay between H3K36me3, methyltransferase SETD2, and mismatch recognition protein MutSα facilitates processing of oxidative DNA damage in human cells
    Sida Guo, Jun Fang, Weizhi Xu, Janice Ortega, Chang-Yi Liu, Liya Gu, Zhijie Chang, Guo‐Min Li · 2022 · Journal of Biological Chemistry
  34. DNA mismatch repair protein MSH2 dictates cellular survival in response to low dose radiation in endometrial carcinoma cells
    Lynn M. Martin, Brian Marples, Anthony Mitchell Davies, Ann Atzberger, Connla Edwards, Thomas Hugh Lynch, Donal P. Hollywood, Laure H. Marignol · 2013 · Cancer Letters
  35. Quantitative trait loci analysis of heat stress resistance of spermatocytes in the MRL/MpJ mouse
    Yuka Namiki, Yasuhiro Kon, Katsuyuki Kazusa, Atsushi Asano, Nobuya Sasaki, Takashi Agui · 2005 · Mammalian Genome
  36. The association between MLH1 -93 G>A polymorphism of DNA mismatch repair and cancer susceptibility: a meta-analysis
    Xin-Min Pan, Wenzhong Yang, Guohui Xu, Peng Bai, Haojie Qin, Lushun Zhang, Xiandun Zhai, Ming Tang, Wei Deng, Lin Zhang et al. · 2011 · Mutagenesis
  37. Multiplexed assays reveal effects of missense variants in MSH2 and cancer predisposition
    Sofie Vincents Nielsen, Rasmus Hartmann‐Petersen, Amelie Stein, Kresten Lindorff‐Larsen · 2021 · PLoS Genetics
  38. Synchronous glioblastoma and medulloblastoma in a child with mismatch repair mutation
    Nisreen Yousef Amayiri, Maysa A. Al-Hussaini, Maisa Swaidan, Imad Jaradat, Monther Qandeel, Uri Y. Tabori, Cynthia E Hawkins, Awni F. Musharbash, Khulood Al‐Saad, Éric Bouffet · 2015 · Child s Nervous System
  39. A New Isoquinolinium Derivative, Cadein1, Preferentially Induces Apoptosis in p53-defective Cancer Cells with Functional Mismatch Repair via a p38-dependent Pathway
    Eun Ryoung Jang, Minsook Ryu, Jeong Eun Park, Jung Ho Kim, Jong‐Soo Lee, Kiwon Song · 2009 · Journal of Biological Chemistry
  40. Correlation between patterns of DNA mismatch repair hmlh1 and hmsh2 protein expression and progression of dysplasia in intraductal papillary mucinous neoplasms of the pancreas
    Adriana Handra‐Luca, Anne Couvelard, Claude Degott, Jean-Fran�ois Fl�jou · 2004 · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin
  41. Exonuclease 1 (Exo1) is required for activating response to SN1 DNA methylating agents
    Eugene Izumchenko, John Saydi, Kevin D. Brown · 2012 · DNA repair
  42. Chromosomal rearrangement as the basis for human tumourigenesis
    Ian R. Radford · 2004 · International Journal of Radiation Biology
  43. MSH6- or PMS2-deficiency causes re-replication in DT40 B cells, but it has little effect on immunoglobulin gene conversion or on repair of AID-generated uracils
    Vanina A. Campo, Anne‐Marie Patenaude, Svenja Kaden, Lori Dawn Horb, Daniel Firka, Josef Jiricny, Javier Marcelo Di Noia · 2013 · Nucleic Acids Research
  44. Functional consequences of DNA mismatch repair missense mutations in murine models and their impact on cancer predisposition
    S.J. Scherer, Elena Avdievich, Winfried Edelmann · 2005 · Biochemical Society Transactions
  45. Checkpoint with forkhead-associated and ring finger promoter hypermethylation correlates with microsatellite instability in gastric cancer
    Eiji Oki, Yan Zhao, Rintaro Yoshida, Takanobu Masuda, Koji Ando, Masahiiko Sugiyama, Eriko Tokunaga, Masaru Morita, Yoshihiro Kakeji, Yoshihiko Maehara · 2009 · World Journal of Gastroenterology
  46. Perspectives for tailored chemoprevention and treatment of colorectal cancer in Lynch syndrome
    Dianne M. Heijink, Elisabeth G.E. de Vries, Jan Jacob Koornstra, Geke A.P. Hospers, Robert M.W. Hofstra, Marcel A.T.M. van Vugt, Steven de Jong, Jan H. Kleibeuker · 2010 · Critical Reviews in Oncology/Hematology
  47. The role of human replicative DNA polymerases in DNA repair and replication
    Anna K. Rytkönen · 2006
  48. Nonrepair functions of DNA mismatch repair proteins: new avenues for precision oncology
    Jerry Tyler DeWitt, Megha Raghunathan, Svasti Haricharan · 2024 · Trends in cancer
  49. Unique clinicopathologic and genetic alteration features in early onset colorectal carcinoma compared with age-related colorectal carcinoma: a large cohort next generation sequence analysis
    David Escobar, Ryan Jones, Juehua Gao, Leyu Sun, Jie Liao, Guang‐Yu Yang · 2020 · Human Pathology
  50. Non-tumor cells from an MSH2-null individual show altered cell cycle effects post-UVB
    Kelly A.D. Narine, Kathleen E. A. Felton, Arabesque Parker, Victor A. Tron, Susan E. Andrew · 2007 · Oncology Reports
  51. Influence of Cell Cycle Checkpoints and p53 Function on the Toxicity of Temozolomide in Human Pancreatic Cancer Cells
    Seema Gupta, S. Sathishkumar, Mansoor M. Ahmed · 2010 · Pancreatology
  52. Targeted Mutations in the ATR Pathway Define Agent-Specific Requirements for Cancer Cell Growth and Survival
    Deborah F. Wilsker, Jon Chung, Iván Felipe Pradilla, Eva Petermann, Thomas Helleday, Fred Bunz · 2011 · Molecular Cancer Therapeutics
  53. I219V Polymorphism in hMLH1 Gene in Patients Affected with Ulcerative Colitis
    Maria Teresa Vietri, Gabriele Riegler, Marialaura De Paola, Serena Simeone, Maria Boggia, IMPROTA A., Mariarita Parisi, Anna Maria Molinari, Michèle Cioffi · 2009 · Genetic Testing and Molecular Biomarkers
  54. Pharmacologic manipulation of the ataxia–telangiectasia mutated gene product as an intervention in age-related disease
    Rodney E. Shackelford · 2005 · Medical Hypotheses
  55. Phosphorylation of SIRT7 by ATM causes DNA mismatch repair downregulation and adaptive mutability during chemotherapy
    Lianhui Sun, Guangjian Fan, Zhuqing Zhang, Dong Chang, Xiaoyu Zhang, Tongqing Zhang, Jichuan Geng, Xiaoxia Zhang, Menghan Lin, Hu Chen et al. · 2025 · Cell Reports
  56. Drug-Sensitive DNA Polymerase δ Reveals a Role for Mismatch Repair in Checkpoint Activation in Yeast
    Linda J. Reha-Krantz, Md. Shahjahan P. Siddique, Kelly M. Murphy, Andrea J. C. Tam, Michelle O’Carroll, Sam Lou, Amy Schultz, Charles M. Boone · 2011 · Genetics
  57. Apoptotic effect of ethyl-4-isothiocyanatobutanoate is associated with DNA damage, proteasomal activity and induction of p53 and p21cip1/waf1
    Juraj Bodo, Jana Jakubı́ková, Ivan Chalupa, Zdena Bartošová, Katarina Horakova, Lubomir Floch, Ján Sedlák · 2006 · APOPTOSIS
  58. Advances in diagnostic and therapeutic applications of mismatch repair loss in cancer
    J. DeWitt, D. Jimenez-Tovar, A. Mazumder, S. Haricharan · 2025 · DNA Repair
  59. Вовлеченность генов белков BRСA1-ассоциированного комплекса наблюдения за геномом (BASC) в развитие многофакторной патологии
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  60. MMR/c-Abl-dependent activation of ING2/p73α signaling regulates the cell death response to N-methyl-N′-nitro-N-nitrosoguanidine
    Guoming Sun, Shunqian Jin, Rathinasamy Baskaran · 2009 · Experimental Cell Research
  61. Integration of Principles of Systems Biology and Radiation Biology: Toward Development of in silico Models to Optimize IUdR-Mediated Radiosensitization of DNA Mismatch Repair Deficient (Damage Tolerant) Human Cancers
    Timothy James Kinsella, Evren Gürkan-Çavusoglu, Weinan Du, Kenneth A. Loparo · 2011 · Frontiers in Oncology
  62. Involvement of Variants in the Genes Encoding BRCA1-Associated Genome Surveillance Complex (BASC) in the Development of Human Common Diseases
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  64. Hypoxia and the DNA Damage Response
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