The BRCA1-interacting helicase BRIP1 is deficient in Fanconi anemia

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Items 201–300 of 370

1. FANCJ is essential to maintain microsatellite structure genome-wide during replication stress
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2. Challenges in the identification and use of rare disease-associated predisposition variants
   Luis G. Carvajal‐Carmona · 2010 · Current Opinion in Genetics & Development
3. BRCA-FA Pathway as a Target for Anti-Tumor Drugs
   Rachel Litman Flynn, Rigu Gupta, Robert M. Brosh, Sharon B. Cantor · 2008 · Anti-Cancer Agents in Medicinal Chemistry
4. Towards a Molecular Understanding of the Fanconi Anemia Core Complex
   Charlotte Hodson, Helen Walden · 2012 · Anemia
5. BRCA1 the Versatile Defender: Molecular to Environmental Perspectives
   Amy X. Zhong, Yumay Chen, Phang‐Lang Chen · 2023 · International Journal of Molecular Sciences
6. The involvement of FANCM, FANCI, and checkpoint proteins in the interstrand DNA crosslink repair pathway is conserved in C. elegans
   Kyong Yun Lee, Kee Yang Chung, Hyeon‐Sook Koo · 2010 · DNA repair
7. Molecular profiles of hereditary epithelial ovarian cancers and their implications for the biology of this disease
   Amir Anthony Jazaeri · 2009 · Molecular Oncology
8. Bone Marrow Failure: A Child Is Not Just a Small Adult (But an Adult Can Have a Childhood Disease)
   Blanche P. Alter · 2005 · Hematology
9. Comprehensive Mutational Analysis of the BRCA1-Associated DNA Helicase and Tumor-Suppressor FANCJ/BACH1/BRIP1
   Jennifer A. Calvo, Briana Fritchman, Desiree Hernandez, Nicole S. Persky, Cory M. Johannessen, Federica Piccioni, Brian A. Kelch, Sharon B. Cantor · 2021 · Molecular Cancer Research
10. An emerging picture of FANCJ’s role in G4 resolution to facilitate DNA replication
    Robert M. Brosh, Yuliang Wu · 2021 · NAR Cancer
11. The Fanconi Anemia Proteins FANCD2 and FANCJ Interact and Regulate Each Other's Chromatin Localization
    Xiaoyong Chen, James B. Wilson, Patricia A. McChesney, Stacy A. Williams, Youngho Kwon, Simonne Longerich, Andrew S. Marriott, Patrick Sung, Nigel J. Jones, Gary M. Kupfer · 2014 · Journal of Biological Chemistry
12. An MLH1 Mutation Links BACH1/FANCJ to Colon Cancer, Signaling, and Insight toward Directed Therapy
    Jenny Xie, Shawna Guillemette, Min Peng, Candace A. Gilbert, Andrew B. Buermeyer, Sharon B. Cantor · 2010 · Cancer Prevention Research
13. Screening for large genomic rearrangements of the BRIP1 and CHK1 genes in Finnish breast cancer families
    Szilvia Sólyom, Katri Pylkäs, Robert Winqvist · 2010 · Familial Cancer
14. Getting Ready for the Dance: FANCJ Irons Out DNA Wrinkles
    Sanjay Bharti, Sanket Awate, Taraswi Banerjee, Robert M. Brosh · 2016 · Genes
15. Patient-derived C-terminal mutation of FANCI causes protein mislocalization and reveals putative EDGE motif function in DNA repair
    Luca Colnaghi, Mathew V. Jones, Xiomaris M. Cotto-Rios, Detlev Schindler, Helmut Hanenberg, Tony T. Huang · 2010 · Blood
16. Validation of Fanconi anemia complementation Group A assignment using molecular analysis
    Nabil N. Moghrabi, Monique Johnson, Marvin J. Yoshitomi, Xiaoman Zhu, Muhsen Al-Dhalimy, Susan B. Olson, Markus Grompe, C. Sue Richards · 2009 · Genetics in Medicine
17. Helicases as Prospective Targets for Anti-Cancer Therapy
    Rigu Gupta, Robert M. Brosh · 2008 · Anti-Cancer Agents in Medicinal Chemistry
18. G-quadruplex-mediated genomic instability drives SNVs in cancer
    Richl, Tilmann, Kuper, Jochen, Kisker, Caroline · 2024 · Nucleic Acids Research
19. First evidence for the contribution of the genetic variations of BRCA1-interacting protein 1 (BRIP1) to the genetic susceptibility of cervical cancer
    X.D. Ma, G.Q. Cai, Wei Zou, Yanhong Huang, J.R. Zhang, D.T. Wang, B.L. Chen · 2013 · Gene
20. Protein Degradation Pathways Regulate the Functions of Helicases in the DNA Damage Response and Maintenance of Genomic Stability
    Joshua A. Sommers, Avvaru N. Suhasini, Robert M. Brosh · 2015 · Biomolecules
21. Association between BRIP1 (BACH1) polymorphisms and breast cancer risk: a meta-analysis
    Noel Pabalan, Hamdi Jarjanazi, Hilmi Özçelik · 2012 · Breast Cancer Research and Treatment
22. The Fanconi Anemia Core Complex Acts as a Transcriptional Co-regulator in Hairy Enhancer of Split 1 Signaling
    Cedric Stevens Tremblay, Caroline Huard, FengFei Huang, Ouassila Habi, Valérie Bourdages, Georges Lévesque, Madeleine Carreau · 2009 · Journal of Biological Chemistry
23. Lack of large genomic deletions in BRIP1, PALB2, and FANCD2 genes in BRCA1/2 negative familial breast cancer
    Najim Ameziane, Ans M.W. van den Ouweland, Muriel A. Adank, R. Vijzelaar, Abdellatif Errami, Josephine C. Dorsman, Hans Joenje, Hanne E.J. Meijers-Heijboer, Quinten Waisfisz · 2009 · Breast Cancer Research and Treatment
24. Biological Function and Medicinal Research Significance of G-Quadruplex Interactive Proteins
    Jun Qiu, Mingxue Wang, Yan Zhang, Ping Zeng, Tian‐Miao Ou, Jia‐Heng Tan, Shi‐Liang Huang, Lin‐Kun An, Honggen Wang, Lian‐Quan Gu et al. · 2015 · Current Topics in Medicinal Chemistry
25. FANCJ helicase controls the balance between short- and long-tract gene conversions between sister chromatids
    Sarmi Nath, Kumar Somyajit, Anup Mishra, Ralph Scully, Ganesh Nagaraju · 2017 · Nucleic Acids Research
26. The DNA-helicase HELLS drives ALK− ALCL proliferation by the transcriptional control of a cytokinesis-related program
    Annalisa Tameni, Elisabetta Sauta, Valentina Mularoni, Federica Torricelli, Gloria Manzotti, Giorgio Inghirami, Riccardo Bellazzi, Valentina Fragliasso, Alessia Ciarrocchi · 2021 · Cell Death and Disease
27. Fanconi Anemia Proteins and Their Interacting Partners: A Molecular Puzzle
    Tagrid Kaddar, Madeleine Carreau · 2012 · Anemia
28. CHL-1 provides an essential function affecting cell proliferation and chromosome stability in Caenorhabditis elegans
    George Chung, Nigel J. O’Neil, Ann M. Rose · 2011 · DNA repair
29. FANCJ Expression Predicts the Response to 5-Fluorouracil-Based Chemotherapy in MLH1-Proficient Colorectal Cancer
    Ryota Nakanishi, Hiroyuki Kitao, Yoshihiko Fujinaka, Nami Yamashita, Makoto Iimori, Eriko Tokunaga, Natsumi Yamashita, Masaru Morita, Yoshihiro Kakeji, Yoshihiko Maehara · 2012 · Annals of Surgical Oncology
30. Clinical characteristics and genetic subtypes of Fanconi anemia in Saudi patients
    Yahya Q. Ghazwani, Mohammed A. Al Balwi, Ibrahim B. Alabdulkareem, Mohammed Al-Dress, Talal Al‐Harbi, Reem M. Al-Sudairy, Ali Alomari, Khalid Aljamaan, Mohammed Al Essa, Mohsen Alzahrani et al. · 2016 · Cancer Genetics
31. HP1 regulates the localization of FANCJ at sites of DNA double‐strand breaks
    Wenwen Wu, Yukiko Togashi, Yoshikazu Johmura, Yasuo Miyoshi, Sachihiko Nobuoka, Makoto Nakanishi, Tomohiko Ohta · 2016 · Cancer Science
32. Ovarian toxicity of carboplatin and paclitaxel in mouse carriers of mutation in BRIP1 tumor suppressor gene
    Elissavet Ntemou, P. Diaz Vidal, Chrysanthi Alexandri, Géraldine Van Den Steen, Matteo Lambertini, Isabelle Demeestere · 2022 · Scientific Reports
33. Insight into the Roles of Helicase Motif Ia by Characterizing Fanconi Anemia Group J Protein (FANCJ) Patient Mutations
    Manhong Guo, Venkatasubramanian Vidhyasagar, Hao Ding, Yuliang Wu · 2014 · Journal of Biological Chemistry
34. Analysis of SLX4/FANCP in non-BRCA1/2-mutated breast cancer families
    Juana Fernández‐Rodríguez, Francisco Quiles, Ignacio Blanco, Àlex Teulé, Lídia Feliubadaló, Jesús Del Valle, Mónica Salinas, Á. Izquierdo, Esther Darder, Detlev Schindler et al. · 2012 · BMC Cancer
35. Aberrant recombination and repair during immunoglobulin class switching in BRCA1-deficient human B cells
    Andrea Björkman, Per Qvist, Likun Du, Margarita Bartish, Apostolos Zaravinos, Konstantinos E. Georgiou, Anders Dupont Børglum, Richard A. Gatti, Therese Törngren, Qiang Pan‐Hammarström · 2015 · Proceedings of the National Academy of Sciences
36. RUNX1 deficiency cooperates with SRSF2 mutation to induce multilineage hematopoietic defects characteristic of MDS
    Yi-Jou Huang, Jiayu Chen, Ming Yan, Amanda G Davis, Sayuri Miyauchi, Liang Chen, Yajing Hao, Sigrid Katz, Rafael L. Bejar, Omar Ibrahim Abdel-Wahab et al. · 2022 · Blood Advances
37. Heterozygous Mutations in DNA Repair Genes and Hereditary Breast Cancer: A Question of Power
    Nathan A. Ellis, Kenneth Offit · 2012 · PLoS Genetics
38. Mechanistic and biological considerations of oxidatively damaged DNA for helicase-dependent pathways of nucleic acid metabolism
    Jack D. Crouch, Robert M. Brosh · 2016 · Free Radical Biology and Medicine
39. Fatal Myelotoxicity Following Palliative Chemotherapy With Cisplatin and Gemcitabine in a Patient With Stage IV Cholangiocarcinoma Linked to Post Mortem Diagnosis of Fanconi Anemia
    Nils W. Engel, Simon Schliffke, Ulrich Schüller, Christian Frenzel, Carsten Bokemeyer, Christian Kubisch, Davor Lessel · 2019 · Frontiers in Oncology
40. Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality
    Ásmundur Oddsson, Patrick Sulem, Garðar Sveinbjörnsson, Gudny Anna Arnadottir, Valgerður Steinthórsdóttir, Gisli Hreinn Halldorsson, Bjarni A. Atlason, Gudjon R. Oskarsson, Hannes Helgason, Henriette Svarre Nielsen et al. · 2023 · Nature Communications
41. Loss of heterozygosity in FANCG, FANCF and BRIP1 from head and neck squamous cell carcinoma of the oral cavity
    Christin Türke, Susanne Horn, Carola Petto, Dirk Labudde, Günter Lauer, Gretel Wittenburg · 2017 · International Journal of Oncology
42. The role of the Fanconi anemia network in the response to DNA replication stress
    Kerstin Gari, Angelos Constantinou · 2009 · Critical Reviews in Biochemistry and Molecular Biology
43. Upregulated ATM Gene Expression and Activated DNA Crosslink-Induced Damage Response Checkpoint in Fanconi Anemia: Implications for Carcinogenesis
    Kazuhiko Yamamoto, Abdallah Nihrane, Jason A. Aglipay, Juan Sironi, Steven Arkin, Jeffrey Michael M Lipton, Toru Ouchi, Johnson M. Liu · 2008 · Molecular Medicine
44. FANCJ at the FORK
    Sharon B. Cantor, Sumeet U. Nayak · 2016 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
45. Mutational analysis of FANCJ helicase
    Manhong Guo, Venkatasubramanian Vidhyasagar, Tanu Talwar, Ahmad Kariem, Yuliang Wu · 2016 · Methods
46. Phenotyping Genetic Diseases Using an Extension of µ-Scores for Multivariate Data
    José F. Morales, Tingting Song, Arleen D. Auerbach, Knut M. Wittkowski · 2008 · Statistical Applications in Genetics and Molecular Biology
47. 17q23.2q23.3 de novo duplication in association with speech and language disorder, learning difficulties, incoordination, motor skill impairment, and behavioral disturbances: a case report
    Karen Wessel, Jehan Suleiman, Tamam Khalaf, Shivendra Kishore, Arndt Rolfs, Ayman W. El‐Hattab · 2017 · BMC Medical Genetics
48. BLM’s balancing act and the involvement of FANCJ in DNA repair
    Srijita Dhar, Robert M. Brosh · 2018 · Cell Cycle
49. Fanconi anemia (FA) and crosslinker sensitivity: Re‐appraising the origins of FA definition
    Giovanni Pagano, Marco d’Ischia, Federico Vicente Pallardó · 2015 · Pediatric Blood & Cancer
50. Two new cases with microdeletion of 17q23.2 suggest presence of a candidate gene for sensorineural hearing loss within this region
    Bitten Schönewolf‐Greulich, Anne Ronan, Kristine Ravn, Peter Baekgaard, Marianne Lodahl, Kate Nielsen, Nanna Dahl Rendtorff, Lisbeth Tranebjærg, Karen Brøndum‐Nielsen, Zeynep Tümer · 2011 · American Journal of Medical Genetics Part A
51. FANCJ DNA helicase is recruited to the replisome by AND-1 to ensure genome stability
    2024
52. Spectrum of variations in dog-1/FANCJ and mdf-1/MAD1 defective Caenorhabditis elegans strains after long-term propagation
    Maja Tarailo‐Graovac, Tammy Wong, Zhaozhao Qin, Stéphane Flibotte, Jon C. Taylor, Donald G. Moerman, Ann M. Rose, Nansheng Chen · 2015 · BMC Genomics
53. Analysis of BRIP1 Variants among Korean Patients with BRCA1/2 Mutation-Negative High-Risk Breast Cancer
    Haeyoung Kim, Dae-Yeon Cho, Doo Ho Choi, Gee Hue Jung, Inkyung Shin, Won Park, Seung Jae Huh, Seok Jin Nam, Jeong Eon Lee, Won Ho Gil et al. · 2016 · Cancer Research and Treatment
54. ERRATUM: "Identifying Mutation Specific Cancer Pathways Using a Structurally Resolved Protein Interaction Network"
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55. The role of BACH1 , BARD1 and TOPBP1 genes in familial breast cancer
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56. Guardians of the Genome: Iron–Sulfur Proteins in the Nucleus
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57. Familial Breast Cancer Risk
    Kara N. Maxwell, Susan M. Domchek · 2013 · Current Breast Cancer Reports
58. Revisiting the Implications of Positive Germline Testing Results Using Multi-gene Panels in Breast Cancer Patients
    Georgios Tsaousis, Eirini Papadopoulou, Κωνσταντίνος Αγιαννιτόπουλος, Georgia Pepe, Νικόλαος Τσούλος, Ioannis Boukovinas, Theofanis Floros, Rodoniki Iosifidou, Ourania Katopodi, Anna A. Koumarianou et al. · 2021 · Cancer Genomics & Proteomics
59. Assembling an orchestra: Fanconi anemia pathway of repair
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60. IDENTIFYING MUTATION SPECIFIC CANCER PATHWAYS USING A STRUCTURALLY RESOLVED PROTEIN INTERACTION NETWORK
    Hatice Billur Engin, Matan Hofree, Hannah K. Carter · 2014 · Pacific Symposium on Biocomputing (PSB)
61. Systematic investigation of BRCA1-A, -B, and -C complexes and their functions in DNA damage response and DNA repair
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62. Inhibited, trapped or adducted: the optimal selective synthetic lethal mix for BRCAness
    Andrew N.J. Tutt · 2017 · Annals of Oncology
63. A Protein Prioritization Approach Tailored for the FA/BRCA Pathway
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64. Association of Single-Nucleotide Polymorphisms in Monoubiquitinated FANCD2-DNA Damage Repair Pathway Genes With Breast Cancer in the Chinese Population
    Feiyu Chen, Hao Wang, Hui Li, Xueli Hu, Xu Dai, Shou-Man Wang, Guo-Jiao Yan, Pinglan Jiang, Yuanping Hu, Juan Huang et al. · 2018 · Technology in Cancer Research & Treatment
65. The repair gene BACH1 - a potential oncogene
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66. Cancer in Fanconi Anemia and Fanconi Anemia Genes in Cancer
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67. Loss of the Fanconi anemia–associated protein NIPA causes bone marrow failure
    Stefanie Kreutmair, Miriam Erlacher, Geoffroy Andrieux, Rouzanna Istvánffy, Alina Rudorf, Melissa Zwick, Tamina Rückert, Milena Pantić, Teresa Poggio, Khalid Shoumariyeh et al. · 2020 · Journal of Clinical Investigation
68. Inherited Bone Marrow Failure Syndromes
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69. Absence of the FANCM c.5101C>T mutation in BRCA1/2-negative triple-negative breast cancer patients from Pakistan
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70. Combining identity by descent and association in genetic case-control studies
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71. TOPBP1 , CLSPN and PALB2 genes in familial breast cancer susceptibility
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72. A DOG’s View of Fanconi Anemia: Insights fromC. elegans
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73. Cytogenetic and molecular diagnosis of Fanconi anemia revealed two hidden phenotypes: Disorder of sex development and cerebro‐oculo‐facio‐skeletal syndrome
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74. Identification, developmental expression and regulation of the Xenopus ortholog of human FANCG/XRCC9
    Stacie Stone, Alexandra Sobeck, Margriet van Kogelenberg, Bendert de Graaf, Hans Joenje, Jan L. Christian, Maureen E. Hoatlin · 2007 · Genes to Cells
75. Helicase-inactivating BRIP1 mutation yields Fanconi anemia with microcephaly and other congenital abnormalities
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76. Iron–Sulfur Clusters: Assembly and Biological Roles
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77. Dominant‐negative pathogenic variant BRIP1 c. 1045G >C is a high‐risk allele for non‐mucinous epithelial ovarian cancer: A case‐control study
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78. BCLAF1, a functional partner of BACH1, participates in DNA damage response
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79. The fanconi anemia pathway promotes homologous recombination repair in DT40 cell line
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80. ADN hélicases et maladies associées
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81. BRCA/Fanconi anemia pathway genes in hereditary predisposition to breast cancer
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82. Hereditary predisposition to breast cancer – with a focus on AATF , MRG15 , PALB2 , and three Fanconi anaemia genes
    Maria K. Haanpää · 2014
83. C t IP ‐ and ATR ‐dependent FANCJ phosphorylation in response to DNA strand breaks mediated by DNA replication
    Ryo Sakasai, Akiko Sakai, Makoto Iimori, Shinichi Kiyonari, Kazuaki Matsuoka, Yoshihiro Kakeji, Hiroyuki Kitao, Yoshihiko Maehara · 2012 · Genes to Cells
84. The mutation landscape of multiple cancer predisposition genes in Chinese familial/hereditary breast cancer families
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85. Four common polymorphisms of BRIP1 (rs2048718, rs4988344, rs4986764, and rs6504074) and cancer risk: evidence from 13,716 cancer patients and 15,590 cancer-free controls
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86. Coregulation of FANCA and BRCA1 in human cells
    Anneke Haitjema, Berber M. Mol, Irsan E. Kooi, Maarten P.G. Massink, Jens AL Jørgensen, Davy Rockx, Martin A. Rooimans, Johan P. de Winter, Hanne E.J. Meijers-Heijboer, Hans Joenje et al. · 2014 · SpringerPlus
87. Fanconi anemia: genetic analysis of a human disease using chicken system
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88. Fanconi anemia in 55‐year‐old identical twins first presenting as fatal post‐chemotherapy pancytopenia
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89. ATM , ATR and Mre11 complex genes in hereditary susceptibility to breast cancer
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90. Risky business: getting a grip on BRIP
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91. Rare genetic diseases associated with G-quadruplex-induced replication stress
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92. Microarray mRNA expression analysis of Fanconi anemia fibroblasts
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93. Ubiquitin and FANC Stress Responses
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94. Faculty Opinions recommendation of Carboplatin in BRCA1/2-mutated and triple-negative breast cancer BRCAness subgroups: the TNT Trial.
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95. Effects of hydrazone-based G-quadruplex ligands on FANCJ/BRIP1-depleted cancer cells and a Caenorhabditis elegans dog-1−/− strain
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96. Association of variations in the Fanconi anemia complementation group and prognosis in Non–small cell lung cancer patients with Platinum-based chemotherapy
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97. Fanconi Anemia: A Pathway of Hematopoiesis and Cancer Predisposition
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98. Identification of new RAD51D-regulating microRNAs that also emerge as potent inhibitors of the Fanconi anemia/homologous recombination pathways
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99. Clonal evolution analyses of a chronic myeloid leukemia patient with hematopoietic stem cell transplantation based on deep sequencing
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100. Ubiquitin and Fanconi Anemia
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