Structural insights into the assembly and activation of IL-1β with its receptors
DOI 10.1038/ni.1925
Cited by (162)
Items 101–162 of 162
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- X‐ray crystal structure localizes the mechanism of inhibition of an IL‐36R antagonist monoclonal antibody to interaction with Ig1 and Ig2 extra cellular domainsEric T. Larson, Debra L. Brennan, Eugene R. Hickey, Rajkumar Ganesan, Rachel Kroe‐Barrett, Neil A. Farrow · 2020 · Protein Science
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- Glycan-mediated functional assembly of IL-1RI: structural insights into completion of the current description for immune responseMaryam Azimzadeh Irani, Mohammad Reza Ejtehadi · 2020 · Journal of Biomolecular Structure and Dynamics
- Dermatologic Manifestations of Noninflammasome-Mediated Autoinflammatory DiseasesDörte Symmank, Carina Borst, Mathias C. Drach, Wolfgang Weninger · 2022 · JID Innovations
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- Macrophage-derived IL-1β directs fibroblast progenitor cell fate via metabolic reprogramming in wound healingHuanyu Luo, Xiaoyi Yu, Tianmeng Sun, Zewen Sun, Tianyuan Zhao, Li Chen, Ana Angelova Volponi, Fabian Flores‐Borja, Hongchen Sun, Zhengwen An · 2025 · Communications Biology
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- In Silico and In Vitro Analysis of IL36RN Alterations Reveals Critical Residues for the Function of the Interleukin-36 Receptor ComplexKaroliina Hassi, Timir Weston, Giulia Rinaldi, Joseph Chi-Fung Ng, Asma Smahi, Sophie Twelves, Camilla S. A. Davan-Wetton, Dana Fakhreddine, Franca Fraternali, Francesca Capon · 2023 · Journal of Investigative Dermatology
- Characterization and Validation of Arg286 Residue of IL-1RAcP as a Potential Drug Target for OsteoarthritisAngela Dailing, Kelsey C. Mitchell, Ngoc Vuong, Kyung Hyeon Lee, Reva Joshi, Virginia A. Espina, Amanda Haymond Still, Carter J. Gottschalk, Anne M. Brown, Mikell A. Paige et al. · 2021 · Frontiers in Chemistry
- Preclinical Efficacy of a Capsid Virus-like Particle-Based Vaccine Targeting IL-1β for Treatment of Allergic Contact DermatitisLouise Goksøyr, Anders B. Funch, Anna Kathrine Okholm, Thor Grundtvig Theander, Willem Adriaan de Jongh, Charlotte Menne Bonefeld, Adam Frederik Sander · 2022 · Vaccines
- Structural Perturbations Present in the Folding Cores of Interleukin-33 and Interleukin-1β Correlate to Differences in Their FunctionV. V. Hemanth Giri Rao, Shachi Gosavi · 2015 · The Journal of Physical Chemistry B
- Beyond Negative Regulation: IL‐1R8 and IL‐1R2 as Novel Immune CheckpointsDomenico Supino, Roberto Garuti, Cecília Garlanda · 2025 · European Journal of Immunology
- Immunomodulatory Activity of Water Extract of Ulmus macrocarpa in MacrophagesDa Hye Kwon, Hye-Joo Kang, Yung Hyun Choi, Kyung Tae Chung, Jong Hwan Lee, Kyung Hwa Kang, Sook Kyung Hyun, Byung Woo Kim, Hye Jin Hwang · 2016 · Journal of Life Science
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- Therapeutic targeting of inflammasome signaling by blocking interleukin-1Rebecca C. Coll · 2022 · Elsevier eBooks
- IL-1 Receptor Accessory Protein-Ig/IL-1 Receptor Type II-Ig Heterodimer Inhibits IL-1 Response More Strongly than Other IL-1 Blocking Biopharmaceutical AgentsHaruo Hanawa, Yoshimi Ota, Limin Ding, He Chang, Kaori Yoshida, Keita Otaki, Kazuhisa Hao, Sou Kasahara, Makoto Kodama, Mikio Nakazawa et al. · 2010 · Journal of Clinical Immunology
- The Interleukin-1 FamilyCharles Anthony Dinarello, Mihai Gheorghe Netea · 2013 · Springer eBooks
- Computational Cosolvent Mapping Analysis Leads to Identify Salicylic Acid Analogs as Weak Inhibitors of ST2 and IL33 BindingXinrui Yuan, Krishnapriya Chinnaswamy, Jeanne A. Stuckey, Chao‐Yie Yang · 2022 · The Journal of Physical Chemistry B
- Identification of critical regions within the TIR domain of IL-1 receptor type IJürgen Radons, Werner Falk, Stefan Dove · 2015 · The International Journal of Biochemistry & Cell Biology
- Cytokine Receptors and Their LigandsKaren S. Cheung Tung Shing, Winnie L. Kan, Tracy L. Nero, Timothy R. Hercus, Denis Tvorogov, Riley D. Metcalfe, Michael D. W. Griffin, Nicole A. de Weerd, Mark A. Guthridge, Paul J. Hertzog et al. · 2022 · Elsevier eBooks
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- Case Study of Hydrogen Bonding in a Hydrophobic CavityYi-Chen Chen, Chao‐Sheng Cheng, Siu-Cin Tjong, Hsien-Sheng Yin, Shih‐Che Sue · 2014 · The Journal of Physical Chemistry B
- Semi-synthetic approaches to bile acids and preclinical evaluation of chenodeoxycholic acid in acute and chronic cutaneous inflammation with docking insightsJuan Carlos Barragán‐Gálvez, Maria L. González-Rivera, Lorena Vanessa Bolaños Sáenz, Sabino de Jesús García Barajas, Abraham Vidal-Limon, Juan Ramón Zapata‐Morales, Mario Alberto Isiordia‐Espinoza, David Cruz Cruz, Angel Josabad Alonso-Castro, Clarisa Villegas Gómez · 2026 · Results in Chemistry
- Regulation of Immunity and Disease by the IL-1 Receptor Family Members IL-1R2 and IL-1R8Martina Molgora, Domenico Supino, Cecília Garlanda · 2018 · Springer eBooks
- Quantitative assessment of extracellular IL-1 regulationLuis F. Ponce, Karina García‐Martínez, Kalet León · 2019 · Journal of Theoretical Biology
- Structural basis of pro-inflammatory signaling via the Interleukin-36 receptor (IL-36R) mediated by IL-36γ and IL-37Julie Andries, Martin Toul, Jan Félix, Danielle M. Clancy, Savvas N. Savvides · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- The Interleukin-1 FamilyCecília Garlanda, Irene Di Ceglie, Sébastien Jaillon · 2025 · Elsevier eBooks
- Characterization of System xc -, a Cystine-Glutamate Amino Acid Transporter, as an Effector of Interleukin-1β-Mediated Injury and NeuroprotectionNicole A. Jackman · 2013 · OpenCommons at University of Connecticut (University of Connecticut)
- Cytokine Receptors and Their LigandsUrmi Dhagat, Tracy L. Nero, Winnie L. Kan, Timothy R. Hercus, Sophie E. Broughton, Nicole A. de Weerd, Brendan John Jenkins, Ashley S. Mansell, Mark A. Guthridge, Paul J. Hertzog et al. · 2015 · Elsevier eBooks
- A genetic and functional analysis of novel chicken interleukin-1 gene family membersMark S. Gibson · 2012 · UCL Discovery (University College London)
- Regulation of ABCB1 expression and activity in porcine brain endothelial cellsPablo Vergara · 2016 · Research Explorer (The University of Manchester)
- Structural Insights into the Assembly of Large Oligomeric Signalosomes in the Toll-Like ReceptorInterle ukin-1 Receptor SuperfamilyRev I Ew · 2016
- Microscale thermophoresis in the investigation of biomolecular interactions2020 · Journal of Chinese Pharmaceutical Sciences
- Autoinflammatory DisordersYoshiro Maru · 2016 · Springer eBooks
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- The role of the interleukin family in neuroinflammation caused by substance dependenceXuan Fan · 2024
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- Integrating multi-omics and machine learning to reveal IL1R2-driven macrophage-fibroblast spatial interactions in polycyclic aromatic hydrocarbon-induced pulmonary fibrosisXin Tang, Peiyi Bai, Qinyang Du, Wulin Yang, Gaopeng Li · 2026 · Frontiers in Immunology